Man

Juan Pablo Acevedo Cox

Profesor Asistente

Universidad de los Andes

Santiago, Chile

Líneas de Investigación


Profesor asistente e Investigador; Ingeniería de Biomateriales y Tecnología de Microfluidos; Ingeniería de Proteínas

Educación

  •  Biología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2003
  •  DOCTOR EN CIENCIAS DE LA INGENIERIA C/M INGENIERIA QUIMICA, UNIVERSIDAD DE CHILE. Chile, 2008

Experiencia Académica

  •   Postdoctoral fellow Full Time

    Max-Planck Institut für Kohlenforschung

    Mûlheim an der Ruhr, Alemania

    2008 - 2011

  •   Visiting Faculty/miembro investigador Full Time

    Harvard-MIT's Division of Health Sciences and Technology

    Boston, Chile

    2011 - 2012

  •   Profesor asistente e Investigador Full Time

    Universidad de los Andes

    Medicina

    Santiago, Chile

    2012 - At present

Experiencia Profesional

  •   Profesor Asistente Full Time

    Universidad de los Andes

    Santiago, Chile

    2012 - At present

Difusión y Transferencia


2016-2018: CORFO Technology Contract (Director). “Development of a new Bioink for cellularized 3D bioprinting of high resolution using the Polyjet technology” 15CONTEC-47942
2015-2017: FONDEF IDEA en dos etapas (Director). “Applied engineering for design and production of small-diameter cellularized coronary graft” ID15I10545

2015-2017: FONDEF IDEA en dos etapas (Investigador Asociado). “Desarrollo de un proceso de síntesis de policaprolactona a partir de ciclohexanona combinando dos reacciones biocatalíticas mediante el uso de dióxido de carbono supercrítico” ID14I10219

2014: Silicon Valley-Go to Market, Corfo, Finalist (Director).

2014-2020: PMI (Institutional Improvement Program): Development of the Biomedical Engineering Research as a Platform to Potentiate the Tissue Engineering and Cell Therapy Research. MECESUP. UAN1301(Principal Investigator).

2013-2016: Corfo, R & D Project line 2: Stemfit: Potency test for adult stem cells, N° 13IDL2-18745 (Director).

2013-2014: MIT-Chile seed Fund for collaborative project with Prof. Robert Langer and Ali Khademhosseini from MIT in Stem cells diagnostic devices (Director).

2011-2012: FAI Fellowship from the University of the Andes for a Visiting Faculty stay at MIT.

2008-2011: Postdoctoral scholarship “Max Planck Society”. Max-Planck-Institut für Kohlenforschung (Prof. Manfred T. Reetz)

2006: Fellowship of University of Chile for patenting process, “Development of industrial enzymes: Cold-active proteases”, Asenjo J.A., Andrews B.A., Acevedo J.P, Reyes F., Burzio L. (US $ 48.000)

2006: Fellowship of OTRI Chile for patenting process, “Development of industrial enzymes: Cold-adapted Lipases”, Asenjo J.A., Andrews B.A., Parra L.P., Reyes F., Acevedo J.P., Burzio L. (US $ 48.000)

2004-2007: Doctoral scholarship “National Commission for Scientific and Technological
Research” CONICYT

2003: Graduated with high honors from Catholic University of Chile, ranked second in generation

2000-2002: Fellowship of John Paul II Foundation, Santiago, Chile



 

Article (20)

Single cell migration profiling on a microenvironmentally tunable hydrogel microstructure device that enables stem cell potency evaluation
Cold-adaptation of a methacrylamide gelatin towards the expansion of the biomaterial toolbox for specialized functionalities in tissue engineering
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries
Microtechnology applied to stem cells research and development
Bioprinted 3D vascularized tissue model for drug toxicity analysis
Layer-by-layer approach for a uniformed fabrication of a cell patterned vessel-like construct
One-step combined focused epPCR and saturation mutagenesis for thermostability evolution of a new cold-active xylanase
Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer-Villiger conversion of cyclohexanone to caprolactone
A New Type of Stereoselectivity in Baeyer–Villiger Reactions: Access to E- and Z-Olefins
Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabile subtilisin-like protease
Coordinated endotelial nitric oxide synthase activation by translocation and phosphorylation determines flow-induced nitric oxide production in resistance vessels
Hydrogel-coated microfluidic channels for cardiomyocyte culture
Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis
Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution
Tuning a P450 Enzyme for Methane Oxidation
Directed evolution of enantioconvergency: the case of an epoxide hydrolase-catalyzed reaction of a racemic epoxide
Induced allostery in the directed evolution of an enantioselective Baeyer-Villiger monooxygenase
Creation of an amino acid network of structurally coupled residues in the directed evolution of a thermostable enzyme
Cloning and fusion expression of a cold-active lipase from marine Antarctic origin
Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique

Abstract (2)

Automated Micro-Fabrication of a Small Diameter Vascular Graft Mimicking the Structure and Mechanical Properties of Human Vessels
A NEW TOOL FOR THE ASSESSMENT OF STEM CELLS (SC) POTENCY USING MICROFLUIDIC-BASED 3D DIRECTED MIGRATION

Proyecto (14)

Arthroscopic device for the treatment of osteoarthritis through 3D bioprinting of chondral lesions
Producción automatizada y escalable de prótesis coronarias bioinspiradas y de pequeño calibre con contenido celular y mecánica natural
Desarrollo de una biotinta para bioimpresión 3D celularizada a alta resolución utilizando la tecnología Polyjet
Desarrollo de un proceso de síntesis de policaprolactona a partir de ciclohexanona combinando dos reacciones biocatalíticas mediante el uso de dióxido de carbono supercrítico
Ingeniería aplicada para diseño y producción de prótesis coronarias celularizadas de pequeño calibre
Desarrollo de una plataforma en Ingeniería biomédica para potenciar la investigación en terapia celular e Ingeniería de Tejidos
Fundamentals of natural polymers and composites for applications in food science and technology, and tissue engineering
A new in vitro migration assay for functional isolation of mesenchymal stem cell subpopulation (MSCs) and therapeutic quality control
Desarrollo de un Test de Potencia Terapéutica, Stemfit, para Células Madre adultas de origen Hematopoyéticas y Mesenquimal
Potency Test for Stem Cell Therapy
Estudio de migración y funcionalidad de subpoblaciones de células madre mesenquimales y desarrollo de dispositivos de migración como nueva herramienta de clasificación y selección de subpoblaciones
Cardiac based microfluidic biosensor
Chemo- and stereoselective methodologies in organic chemistry using protein engineering and directed evolution of enzymes (Lipases, Epoxide Hydrolases and monooxygenases)
Research, Development and Production of Comercial Cryophilic Proteases and Lipases from Antartic Krill and Bacteria
10
Juan Pablo Acevedo

Profesor Asistente

Universidad de los Andes

Santiago, Chile

5
Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

2
Javier Enrione

Profesor Titular

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

1
Flavia Zacconi

Associate Professor

Organic Chemistry

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Claudio Garcia

Associate Professor

Departamento de Ingenieria Mecanica

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Paulo Diaz

Profesor Asociado

Escuela de Nutrición y Dietética

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Cristina Padilla

Administrador de laboratorio e Investigador

Centro de Investigaciones Biomedicas

Universidad de Los Andes

Santiago, Chile

1
Patricia Luz

Profesor asistente

Universidad de los Andes

Santiago , Chile

1
Loreto Valenzuela

Profesor Asociado

Ingeniería Química y Bioprocesos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Franck Quero

Profesor Asociado

Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

1
Franck Quero

Profesor Asistente

Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

1
Karina Pino

Group Leader/Associate Professor

Centro de Investigación Biomédica

Universidad de los Andes

Santiago, Chile

1
gabriela zavala

Investigador post-doctoral

Cells for Cells

Universidad de los Andes

Santiago, Chile

1
Camila Wilkens

COO

IctioBiotic

Santiago, Chile

1
jose Vargas

profesor asistente adjunto

cirugia vascular y endovascular

Pontificia Universidad Católica de Chile

santiago, Chile