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María Lorena Oróstica Arévalo

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 2016
Bioquimico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2009
Licenciatura en Bioquimica, UNIVERSIDAD DE CHILE. Chile, 2009


Molecular Mechanisms of Androstenediol in the Regulation of the Proliferative Process of Human Endometrial Cells Plaza-Parrochia, Francisca; Oróstica, Lorena; García, Paula; Vera, Carolina; Romero, Carmen; Valladares, Luis; Vega, Margarita Article Reproductive Sciences (2017)
Prolactin gene expression in the pituitary of rats subjected to vaginocervical stimulation requires Erk-1/2 signaling. Reuquen, Patricia; Guajardo-Correa, Emanuel; Oróstica, María L; Curotto, Constanza; Parada-Bustamante, Alexis; Cardenas, Hugo; Orihuela, Pedro A Article Reproductive biology (2017)
Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer Retamales-Ortega, Rocío; Oróstica, Lorena; Vera, Carolina; Cuevas, Paula; Hernández, Andrea; Hurtado, Iván; Vega, Margarita; Romero, Carmen Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells Vera, Carolina Andrea; Oróstica, Lorena; Gabler, Fernando; Ferreira, Arturo; Selman, Alberto; Vega, Margarita; Romero, Carmen Aurora Article INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas, C; Orostica, L; Poblete, C; Carvajal, R; Gabler, F; Romero, C; Lavandero, S; Vega, M Article ISI REPRODUCTIVE SCIENCES (2016)
Proinflammatory environment and role of TNF-alpha in endometrial function of obese women having polycystic ovarian syndrome Orostica, L; Astorga, I; Plaza-Parrochia, F; Vera, C; Garcia, V; Carvajal, R; Gabler, F; Romero, C; Vega, M Article ISI SCOPUS INTERNATIONAL JOURNAL OF OBESITY (2016)
Endometria from Obese PCOS Women with Hyperinsulinemia Exhibit Altered Adiponectin Signaling Garcia V, Oróstica L.; Poblete, C; Rosas C, Astorga; I, Romero C Article Hormone and Metabolic Research (2015)
Estradiol increases IP3 by a nongenomic mechanism in the smooth muscle cells from the rat oviduct Reuquén P, Orostica ML; Rojas I, Díaz P; parada Bustamante A, orihuela pa Article Reproduction (2015)
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas C, Oróstica L.; Poblete, C; Carvajal R, Gabler F; Romero C, Lavandero S Article Reproductive Sciences (2015)
Estradiol increases cAMP in the oviductal secretory cells through a nongenomic mechanism Orostica ML, Lopez J; Rojas I, Rocco; J, Díaz P; Reuquén P, Cardenas H; parada Bustamante A, orihuela pa Article Reproduction (2014)
Mating Decreases Plasma Levels of TGF beta 1 and Regulates Myosalpinx Expression of TGF beta 1/TGFBR3 in the Rat Orostica M.L., Lopez J; Zuniga L.M., Utz D.; Díaz P, Reuquén P; parada Bustamante A, Cardenas H Article Molecular Reproduction and Development (2014)
Changes in the gene expression pattern induced by 2-methoxyestradiol in the mouse uterus Rincon-Rodriguez, RJ; Orostica ML, Díaz P; Reuquén P, Cardenas H Article Endocrine (2013)
Tumour necrosis factor-alpha is the signal induced by mating to shutdown a 2-methoxyestradiol nongenomic action necessary to accelerate oviductal egg transport in the rat Orostica ML, Zuñiga LM; Utz D., parada Bustamante A; Velasquez LA, Cardenas H Article Reproduction (2013)
A non-genomic signaling pathway shut down by mating changes the estradiol-induced gene expression profile in the rat oviduct parada Bustamante A, orihuela pa; Rios M, Cuevas CA; Orostica ML, Velasquez LA; Villalón MJ, Croxatto HB Article Reproduction (2010)


Advanced Center for Chronic Diseases (ACCDiS) FONDAP (15130011) Proyecto 2017-2018 Postdoctorado
Role of nerve growth factor on the regulation of miRNA-23b and -145 and inflammatory molecules involved in cell proliferation and tumor angiogenesis of epithelial ovarian cancer FONDECYT (1160139) Proyecto 2016-2020 Personal técnico y/o de apoyo
Involvement of Adiponectin in the Regulation of Endometrial Metabolic Function of Obese Women bearing Polycystic Ovarian Syndrome and Hyperinsulinism FONDECYT (1130053) Proyecto 2013-2016 Tesista
Signaling Cascades Elucitaded by TNF-alpha to shut down an estradiol non-genomic pathway in oviductal epithelial cells FONDECYT (1110662) Proyecto 2011-2014 Personal técnico y/o de apoyo
Proyecto BASAL=> Centro para el Desarrollo de Nanociencia y Nanotecnología (CEDENNA) FONDAP (FB08-07) Proyecto 2009-2015 Personal técnico y/o de apoyo
Mecanismos celulares y moleculares activados por el coito implicados en el silenciamiento de la vía de señalización no-genómica del estradiol en el oviducto FONDECYT (1080523) Proyecto 2008-2010 Personal técnico y/o de apoyo
Mecanismos celulares y moleculares activados por el coito implicados en el silenciamiento de la vía de señalización no-genómica del estradiol en el oviducto FONDECYT (1080523) Proyecto 2008-2010 Tesista


Exosomes in bile as potential pancreatobiliary tumor biomarkers Sagredo, AI; Sepulveda, SA; Roa, JC; Orostica, L Review ISI SCOPUS Translational Cancer Research (2017)
Altered Steroid Metabolism and Insulin Signaling in PCOS Endometria: Impact in Tissue Function Orostica, L; Rosas, C; Plaza-Parrochia, F; Astorga, I; Gabler, F; Garcia, V; Romero, C; Vega, M Review ISI SCOPUS CURRENT PHARMACEUTICAL DESIGN (2016)
The role of mating in oviduct biology Parada-Bustamante, A; Orostica, ML; Reuquen, P; Zuniga, LM; Cardenas, H; Orihuela, PA Review ISI SCOPUS MOLECULAR REPRODUCTION AND DEVELOPMENT (2016)

María Oróstica

Santiago Sepúlveda

Profesional Tecnólogo Médico

Anatomía Patológica

Pontificia Universidad Católica de Chile

Santiago, Chile

Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

Patricia Reuquén

PROFESOR POR HORA

BIOLOGIA

Universidad de Santiago de Chile

SANTIAGO, Chile

Alexis Parada

PROFESOR ASOCIADO

REPRODUCCION

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

María Lorena Oróstica Arévalo

Líneas de Investigación

Educación

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 2016

Bioquimico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2009

Licenciatura en Bioquimica, UNIVERSIDAD DE CHILE. Chile, 2009

Article (14)

Molecular Mechanisms of Androstenediol in the Regulation of the Proliferative Process of Human Endometrial Cells

Prolactin gene expression in the pituitary of rats subjected to vaginocervical stimulation requires Erk-1/2 signaling.

Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer

The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells

Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells

Proinflammatory environment and role of TNF-alpha in endometrial function of obese women having polycystic ovarian syndrome

Endometria from Obese PCOS Women with Hyperinsulinemia Exhibit Altered Adiponectin Signaling

Estradiol increases IP3 by a nongenomic mechanism in the smooth muscle cells from the rat oviduct

Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells

Estradiol increases cAMP in the oviductal secretory cells through a nongenomic mechanism

Mating Decreases Plasma Levels of TGF beta 1 and Regulates Myosalpinx Expression of TGF beta 1/TGFBR3 in the Rat

Changes in the gene expression pattern induced by 2-methoxyestradiol in the mouse uterus

Tumour necrosis factor-alpha is the signal induced by mating to shutdown a 2-methoxyestradiol nongenomic action necessary to accelerate oviductal egg transport in the rat

A non-genomic signaling pathway shut down by mating changes the estradiol-induced gene expression profile in the rat oviduct

Proyecto (7)

Advanced Center for Chronic Diseases (ACCDiS)

Role of nerve growth factor on the regulation of miRNA-23b and -145 and inflammatory molecules involved in cell proliferation and tumor angiogenesis of epithelial ovarian cancer

Involvement of Adiponectin in the Regulation of Endometrial Metabolic Function of Obese Women bearing Polycystic Ovarian Syndrome and Hyperinsulinism

Signaling Cascades Elucitaded by TNF-alpha to shut down an estradiol non-genomic pathway in oviductal epithelial cells

Proyecto BASAL=> Centro para el Desarrollo de Nanociencia y Nanotecnología (CEDENNA)

Mecanismos celulares y moleculares activados por el coito implicados en el silenciamiento de la vía de señalización no-genómica del estradiol en el oviducto

Mecanismos celulares y moleculares activados por el coito implicados en el silenciamiento de la vía de señalización no-genómica del estradiol en el oviducto

Review (3)

Exosomes in bile as potential pancreatobiliary tumor biomarkers

Altered Steroid Metabolism and Insulin Signaling in PCOS Endometria: Impact in Tissue Function

The role of mating in oviduct biology

María Oróstica

Santiago Sepúlveda

Carmen Romero

Patricia Reuquén

Alexis Parada

Juan Roa