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Leonardo Esteban Guzman Martinez

Investigador Asociado

Centro Internacional de Biomedicina ICC

Santiago, Chile

Desarrollo de biomarcadores diagnóstico y nuevas terapias para enfermedades neurodegenerativas como la enfermedad de Alzheimer.

Bioquimico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2006
Ciencias y Humanidades, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000

Profesor ayudante de laboratorio Other

UNIVERSIDAD DE SANTIAGO DE CHILE

Quimica y Biología

Santiago, Chile

2002 - 2002
Profesor ayudante de laboratorio Other

UNIVERSIDAD DE SANTIAGO DE CHILE

Química y Biología

Santiago, Chile

2002 - 2005

Investigador asistente Full Time

Fundación Biociencia

Santiago, Chile

2005 - 2008
Investigador Asistente Full Time

Internacional Center for Biomedicine ICC

Santiago, Chile

2009 - 2014
Investigador Asociado Full Time

Internacional Center for Biomedicine ICC

Santiago, Chile

2014 - A la fecha


Biomarkers for Alzheimer's Disease Guzman-Martinez, Leonardo; Maccioni, Ricardo B.; Farías, Gonzalo A.; Fuentes, Patricio; Navarrete, Leonardo P. Article ISI SCOPUS CURRENT ALZHEIMER RESEARCH (2019)
CDK5: A Unique CDK and Its Multiple Roles in the Nervous System Cortes, Nicole; Guzman-Martinez, Leonardo; Andrade, Victor; Gonzalez, Andrea; Maccioni, Ricardo B Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2019)
The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population Guzman-Martinez, Leonardo; Tapia, Jose; Farias, Gonzalo A.; Gonzalez, Andrea; Estrella, Matias; Maccioni, Ricardo B Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2019)
Alzheimer´s Disease in the Perspective of Neuroimmunology Maccioni, Ricardo B; González, Andrea; Andrade, Víctor; Cortés, Nicole; Tapia, José Pablo; Guzmán-Martínez, Leonardo Article SCOPUS Open Neurology Journal (2018)
Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease Slachevky, Andrea; Guzman-Martinez, Leonardo; Delgado, Carolina Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2017)
Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer’s Disease Slachevsky, Andrea; Guzmán-Martínez, Leonardo; Delgado, Carolina; Reyes, Pablo; Farías, Gonzalo A.; Muñoz-Neira, Carlos; Bravo, Eduardo; Farías, Mauricio; Flores, Patricia; Garrido, Cristian; Becker, James T.; López, Oscar L.; Maccioni, Ricardo B.; Caramelli, Paulo Article Journal of Alzheimer's Disease (2016)
Biochemical Markers for Alzheimer’s and Parkinson’s Disease Farias, GA.; Arata, L.; Guzmán-Martínez, L.; Morales, I.; Tapia, JP.; Maccioni, RB. Article (2015)
Molecules of the Quinoline Family Block Tau Self-Aggregation: Implications Toward a Therapeutic Approach for Alzheimer's Disease Navarrete, L.P.; Guzman, L; San Martin, A; Astudillo Saavedra L.; Maccioni, R. B. Article ISI SCOPUS Journal of Alzheimer's Disease (2012)
Shilajit: A natural phytocomplex with potential procognitive activity Carrasco-Gallardo C.; Guzman, L; Maccioni, R. B. Article SCOPUS International Journal of Alzheimer's Disease (2012)
Mechanisms of tau self-aggregation and neurotoxicity FarÃas G.; Cornejo A.; JimÃ©nez J.; GuzmÃ¡n L.; Maccioni, R. B. Article ISI SCOPUS Current alzheimer Research (2011)


Tau Platelets Biomarker Correlates with Clinical Features of Alzheimer's Disease Slachevsky, A; Delgado C.; Guzman, L; Reyes, P; Farías G.; Lopez, O; Becker, J.; Munoz-Neira, C; Bravo, E.; Flores P.; Maccioni, R Abstract ISI NEUROLOGY (2013)


The promise for Alzheimer´s disease treatment: bioactive compounds Andrade, Victor; Guzman-Martinez, Leonardo; Cortes, Nicole; Maccioni, Ricardo Benjamin; Ghosh, Dilip; Mukherjee, Pulok K BookSection (2019)
Neuroimmune Dynamics in Alzheimer’s Disease Progression Andrade, Victor; Guzman-Martinez, Leonardo; Vergara-Pulgar, Katiana; Maccioni, Ricardo Benjamin; Aranda-Abreu, Gonzalo BookSection (2017)


Pathway to Tau Modifications and the Origins of Alzheimers Disease Maccioni, RB; Tapia, JP; Guzman-Martinez, L EditorialMaterial ISI SCOPUS ARCHIVES OF MEDICAL RESEARCH (2018)


Biomarcador para Alzheimer. maccioni, ricardo; Guzman-Martinez, Leonardo Proyecto (0)


Neuroinflammation as a Common Feature of Neurodegenerative Disorders Guzman-Martinez L.; Maccioni, R. B.; Andrade V.; Navarrete, L.P.; Pastor M.G.; Ramos-Escobar N. Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
Neuroimmune Tau Mechanisms: Their Role in the Progression of Neuronal Degeneration Cortes N.; Andrade, V; Guzman-Martinez, L; Estrella, M; Maccioni, RB Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches Morales, I; Guzman-Martinez, L; Cerda-Troncoso, C; Farias, GA; Maccioni, RB Review ISI FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Nutraceuticals: A Novel Concept in Prevention and Treatment of Alzheimer's Disease and Related Disorders Farías, Gonzalo A.; Guzmán-Martínez, Leonardo; Delgado, Carolina; Maccioni, Ricardo B Review ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2014)
Tau oligomers as potential targets for Alzheimer's diagnosis and novel drugs Guzman-Martinez, L; Farias, GA; Maccioni, RB Review ISI FRONTIERS IN NEUROLOGY (2013)
Emerging Noninvasive Biomarkers for Early Detection of Alzheimer's Disease Guzman-Martinez, L; Farías G.A.; Maccioni, R. B. Review ISI SCOPUS Archives of Medical Research (2012)

21

Leonardo Guzman

Investigador Asociado

Diagnóstico

Centro Internacional de Biomedicina ICC

Santiago, Chile

15

Ricardo Maccioni

DIRECTOR

RESEARCH AND DEVELOPMENT

CENTRO INTERNACIONAL DE BIOMEDICINA (ICC)

SANTIAGO, Chile

5

Gonzalo Farías

Profesor Asistente

Departamento de Neurología y Neurocirugía Norte y Departamento de Neurociencias

Facultad de Medicina, Universidad de Chile

Santiago, Chile

3

CAROLINA DELGADO

ASSOCIATE PROFESSOR

NEUROLOGÍA y neurocirugía

HOSPITAL CLINICO UNIVERSIDAD DE CHILE

SANTIAGO, Chile

3

Nicole Cortés

Coordinadora de Estudios Clínicos

Laboratorio de Biología Celular, Molecular y Neurociencias, Corporación Centro Internacional de Biomedicina, ICC

Santiago, Chile

3

Andrea González

Investigadora Asociada

CENTRO INTERNACIONAL DE BIOMEDICINA (ICC)

Santiago, Chile

2

Leonardo Navarrete

Jefe de Laboratorio

Centro Internacional de Biomedicina

Santiago, Chile

1

José Tapia

Ingeniero de Proyectos

Corporación Centro Internacional de Biomedicina

Santiago, Chile

1

Andrea Slachevsky

Associate Professor

ICBM

UNIVERSIDAD DE CHILE

Chile, Chile

1

José Jiménez

Postdoc

Investigación

Fundacion Ciencia y Vida

Santiago, Chile

1

Patricio Fuentes

Medico Neurologo

Medicina

Hospital Clínico Universidad de Chile

Santiago, Chile

1

AURELIO SAN MARTIN

Profesor Asociado (media jornada)

de Ciencias y Recursos Naturales

FACULTAD DE CIENCIAS

Punta Arenas, Chile