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Sebastián Daniel Aguayo Paul

Assistant Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Biofilm-mediated diseases Bacterial adhesion to surfaces and biofilm formation Collagen alterations in dentistry Collagen biomaterials

Educación

  •  Biomaterials, UNIVERSITY COLLEGE LONDON. Reino Unido, 2017
  •  Dentistry, UNIVERSIDAD DE CONCEPCION. Chile, 2011
  •  Dentistry, UNIVERSIDAD DE CONCEPCION. Chile, 2011
  •  Education, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2020

Experiencia Académica

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2017 - A la fecha

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Instituto de Ingeniería Biológica y Médica (IIBM)

    Santiago, Chile

    2020 - A la fecha

Experiencia Profesional

  •   Dentist Part Time

    Odontocentro

    Chile

    2011 - 2013

  •   Research Assistant Other

    GSK

    Reino Unido

    2016 - 2016

Premios y Distinciones

  •   Best Researcher School of Dentistry

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2018

    2018 Best Researcher for the School of Dentistry, at the Faculty of Medicine annual meeting

  •   1st Place Eastman Dental Institute Postgraduate Research Prize

    UNIVERSITY COLLEGE LONDON

    Reino Unido, 2016

    1st place PhD prize at the 2016 Eastman Dental Institute Postgraduate Day, UCL, London


 

Article (29)

Aloe vera peel-derived nanovesicles display anti-inflammatory properties and prevent myofibroblast differentiation
Microfabrication-based engineering of biomimetic dentin-like constructs to simulate dental aging
Applied biophysics of the tooth and dental materials
Atomic force microscopy-mediated mechanobiological profiling of complex human tissues
Modulation of the biophysical and biochemical properties of collagen by glycation for tissue engineering applications
Nanoscale Dynamics of Streptococcal Adhesion to AGE-Modified Collagen
Quantitative nanohistology of aging dermal collagen
Royal jelly extracellular vesicles promote wound healing by modulating underlying cellular responses
Case-based learning to teach scientific thinking to dental students
Nanomechanical and Molecular Characterization of Aging in Dentinal Collagen
Ultrastructural characterisation of young and aged dental enamel by atomic force microscopy
Antibacterial Effect of Honey-Derived Exosomes Containing Antimicrobial Peptides Against Oral Streptococci
Bacterial adhesion to collagens: implications for biofilm formation and disease progression in the oral cavity
Dependency of hydration and growth conditions on the mechanical properties of oral biofilms
Modulatory Effect of Glycated Collagen on Oral Streptococcal Nanoadhesion
Complex Interaction between Resident Microbiota and Misfolded Proteins: Role in Neuroinflammation and Neurodegeneration
In Vivo Relationship between the Nano-Biomechanical Properties of Streptococcal Polysaccharide Capsules and Virulence Phenotype
Type I collagen hydrogels as a delivery matrix for royal jelly derived extracellular vesicles
Exosome-like vesicles in Apis mellifera bee pollen, honey and royal jelly contribute to their antibacterial and pro-regenerative activity
Phenotypic Properties of Collagen in Dentinogenesis Imperfecta Associated with Osteogenesis Imperfecta
A Multi-scale Biophysical Approach to Develop Structure-Property Relationships in Oral Biofilms
Early Adhesion of Candida albicans onto Dental Acrylic Surfaces.
Quantitative nanohistological investigation of scleroderma=> an atomic force microscopy-based approach to disease characterization.
Influence of biomaterial nanotopography on the adhesive and elastic properties of Staphylococcus aureus cells
Mechanics of Bacterial Cells and Initial Surface Colonisation.
Probing the nanoadhesion of Streptococcus sanguinis to titanium implant surfaces by atomic force microscopy.
A simple and robust method for pre-wetting poly (lactic-co-glycolic) acid microspheres.
Nanoadhesion of Staphylococcus aureus onto Titanium Implant Surfaces.
Single-bacterium nanomechanics in biomedicine=> unravelling the dynamics of bacterial cells.

Proyecto (4)

EFFECT OF METHYLGLYOXAL-DERIVED ADVANCED GLYCATION END-PRODUCTS ON STREPTOCOCCUS MUTANS DYSBIOTIC COLONIZATION IN ROOT CARIES
Influence of age-derived dental collagen glycation on bacterial adhesion and initial biofilm formation of oral streptococci.
Candida albicans adhesion to acrylic dental surfaces at the nanoscale
Early-stage adhesion of microbes onto oral biomaterials at the nanoscale

Review (2)

Potential Novel Strategies for the Treatment of Dental Pulp-Derived Pain: Pharmacological Approaches and Beyond
Association between Alzheimers Disease and Oral and Gut Microbiota: Are Pore Forming Proteins the Missing Link?
24
Sebastián Aguayo

Assistant Professor

Dentistry

Pontificia Universidad Católica de Chile

Santiago, Chile

9
Christina Schuh

Assistant Professor

Centre for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

4
Nelson Barrera

Associate Professor

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

3
simon alvarez

Asistente de investigación

Facultad de Medicina

Universidad del Desarrollo

Santiago, Chile

2
Bruna Benso

Profesora Asistente

Facultad de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
gabriela zavala

Investigador post-doctoral

Cells for Cells

Universidad de los Andes

Santiago, Chile

1
Claudia Véliz

Profesor Asociado

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Cynthia Cantarutti

Profesor Asociado

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Benjamin Vicente

Director de Departamento

Psiquiatría y Salud Mental

FACULTAD DE MEDICINA UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

1
Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

1
Duniel Ortuño

Profesor e Investigador

Odontología

Universidad de Los Andes

Santiago de Chile, Chile