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Juan Pablo González Gutiérrez

Desarrollo y diseño de nuevos compuestos orgánicos con potencial actividad farmacológica sobre los receptores nAChR, mAChR M1, inhibidores AChE, SERT y DAT.

Química, UNIVERSIDAD DE CHILE. Chile, 2020
Licenciado en Ciencias con mencion en Quimica, UNIVERSIDAD DE CHILE. Chile, 2013

academico a honorarios Other

UNIVERSIDAD DE CHILE

ciencias quimicas y farmaceuticas

Santiago, Chile

2017 - A la fecha
Docente Adjunto Part Time

UNIVERSIDAD SAN SEBASTIAN

MEDICINA Y CIENCIA

Santiago, Chile

2021 - A la fecha
PROFESOR INVESTIGADOR Full Time

UNIVERSIDAD AUTONOMA DE CHILE

FACULTAD DE INGENIERIA

TALCA, Chile

2022 - A la fecha

Profesor Quimica Full Time

Preuniversitario Universidad Catolica

Santiago, Chile

2019 - A la fecha

1) Desing and synthesis of new ligands with activity on AChE and affinity on SERT - Damian Castillo Ríos y Maisa Orellana Contreras. Química y Farmacia, Facultad de Salud, Universidad Autonoma de Chile. 2024

2) Synthesis and Antibacterial Evaluation of Novel 1,2,3,4-Tetrahydroisoquinoline Derivatives Against Staphylococcus aureus and Escherichia coli - Valentina Valenzuela Fuentes. Química y Farmacia, Facultad de Salud, Universidad Autonoma de Chile. 2024


SYNTHESIS OF NOVEL LIPOIC ACID DERIVATIVES Juan Pablo Gonzï¿½lez-Gutiï¿½rrez; S. Moris; C. Barrientos Article SCIELO Journal of the Chilean Chemical Society (2024)
SYNTHESIS OF NOVEL NEONICOTINOIDS DERIVATIVES Juan Pablo Gonzï¿½lez; Silvana Moris; Claudio Barrientos Article ISI SCIELO Journal of the Chilean Chemical Society (2023)
UFR2709, an Antagonist of Nicotinic Acetylcholine Receptors, Delays the Acquisition and Reduces Long-Term Ethanol Intake in Alcohol-Preferring UChB Bibulous Rats Gonzalez-Gutierrez, Juan Pablo; Quilaqueo, Maria Elena Article ISI BIOMEDICINES (2022)
Nicotinic Antagonist UFR2709 Inhibits Nicotine Reward and Decreases Anxiety in Zebrafish Quiroz, Gabriel Article ISI MOLECULES (2020)
Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues Hodar M.; Viscarra F.; Paillali P.; Guerra-DÃaz N.; HernÃ¡ndez-Morantes J.J.; PÃ©rez-SÃ¡nchez H.; BermÃºdez I. Article ISI SCOPUS MOLECULES (2019)
Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine alpha 4 beta 2, Dopamine and Serotonin Transporters GonzÃ¡lez-GutiÃ©rrez J.P.; Pessoa-Mahana H.A.; Iturriaga-VÃ¡squez P.E.; Reyes-Parada M.I.; Guerra-DÃaz N.E.; Hodar-Salazar M.; Lorca-Carvajal M.A.; ZÃºÃ±iga M.C. Article ISI SCOPUS MOLECULES (2019)
UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats Vizcarra F.; Bermudez I.; Quintanilla M.E.; Lagos D. Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
Neonicotinic analogues: Selective antagonists for alpha 4 beta 2 nicotinic acetylcholine receptors Faundez-Parraguez, M; Farias-Rabelo, N; Gonzalez-Gutierrez, JP; Etcheverry-Berrios, A; Alzate-Morales, J; Adasme-Carreno, F; Varas, R.; Bermudez I.; Iturriaga-Vasquez, P Article ISI SCOPUS Bioorganic and Medicinal Chemistry (2013)


Design, Synthesis and Pharmacological Evaluation of Dual Nicotinic Agonist and MAO-B Inhibitors Activity for Regulation of Dopamine Level in the Brain. FONDECYT (1100452) Proyecto 2010-2013 Personal técnico y/o de apoyo