PDI - Resultado de Búsqueda

Alejandro Castro Alvarez

Académico

Universidad de La Frontera

Temuco, Chile

Química orgánica computacional, organocatálisis, química medicinal

Organic Chemistry, UNIVERSIDAD DE BARCELONA. España, 2018
Computational Organic Chemistry, UNIVERSIDAD DE BARCELONA. España, 2013
Pharmacist, UNIVERSIDAD CATOLICA DEL NORTE. Chile, 2009

Académico Full Time

UNIVERSIDAD DE LA FRONTERA

Facultad de Medicina

Temuco, Chile

2021 - A la fecha


New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs Vesela, Denisa; Vojackova, Veronika; Faúndez, Mario; Strnad, Miroslav Article ISI PHARMACEUTICS (2024)
Nickel(II)-Catalyzed Formal [3+2] Cycloadditions between Indoles and Donor-Acceptor Cyclopropanes Nachtigall, Fabiane M.; Reis, Francisco A. A.; Santos, Leonardo S. Article ISI Molecules (2024)
Application of Synchrotron Radiation-Based Fourier-Transform Infrared Microspectroscopy for Thermal Imaging of Polymer Thin Films Ng, Ryan C.; Sandell, Susanne; He, Jianying; Torres, Clivia M. Sotomayor; Kreuzer, Martin Article ISI POLYMERS (2023)
Exploring the Potential of Green Hydrogen Production and Application in the Antofagasta Region of Chile Sapunar, Nicolas; Henríquez, Francisco; Saavedra, Javier; Rodriguez, Sebastian; Cornejo, Ivan Article ISI Energies (2023)
Improved High Temperature Thermoelectric Properties in Misfit Ca<sub>3</sub>Co<sub>4</sub>O<sub>9</sub> by Thermal Annealing Chatterjee, Arindom; El Sachat, Alexandros; Banik, Ananya; Biswas, Kanishka; Sotomayor Torres, Clivia M. M. Article ISI Energies (2023)
In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies Garate, Jose Antonio; Morales, Cesar; Mella, Jaime Article ISI JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2023)
Computational Comparison of the Stability of Iminium Ions and Salts from Enals and Pyrrolidine Derivatives (Aminocatalysts) Fillot, Daniel Article ISI EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2022)
Computational Study of the Stability of Pyrrolidine-Derived Iminium Ions: Exchange Equilibria between Iminium Ions and Carbonyl Compounds Article ISI ACS OMEGA (2022)
Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis Bustos, Luis Article ISI Molecules (2022)
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia Bertrand, Jeanluc; Dostalova, Hana; Krystof, Vladimir; Jorda, Radek; Delgado, Thalia; Mella, Jaime; Faúndez, Mario Article ISI PHARMACEUTICS (2022)
Spectroscopic and Thermal Characterization of Extra Virgin Olive Oil Adulterated with Edible Oils Puertas, Blanca; Soliva Fortuny, Robert Article ISI FOODS (2022)
Substituted Purines as High-Affinity Histamine H<sub>3</sub> Receptor Ligands Leitzbach, Luisa; Anazco, Tito; Silva, Maria J.; Stark, Holger Article ISI PHARMACEUTICALS (2022)
Synthesis, antitumor activity, 3D-QSAR and molecular docking studies of new iodinated 4-(3H)-quinazolinones 3N-substituted Puelles, Arturo Article ISI RSC ADVANCES (2022)
Thermal Rectification and Thermal Logic Gates in Graded Alloy Semiconductors Sotomayor-Torres, Clivia M. Article ISI Energies (2022)
Amino-Catalyzed Reactions of Aldehydes with Chiral Nitroalkenes Cascales, Victor; Carneros, Hector; Costa, Anna M.; Vilarrasa, Jaume Article ISI ORGANIC LETTERS (2021)
Convergent synthesis, drug target prediction, and docking studies of new 2,6,9-trisubstituted purine derivatives Villegas, Alondra; Ballesteros-Casallas, Andres; Castro, Alejandro Article ISI JOURNAL OF HETEROCYCLIC CHEMISTRY (2021)
Review on Sol-Gel Synthesis of Perovskite and Oxide Nanomaterials Article ISI GELS (2021)
Understanding the Molecular Basis of 5-HT4 Receptor Partial Agonists through 3D-QSAR Studies Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
High performance single-molecule magnets, Orbach or Raman relaxation suppression? Aravena, Daniel Article ISI INORGANIC CHEMISTRY FRONTIERS (2020)
New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia Bertrand J.; DostÃ¡lovÃ¡ H.; Krystof V.; Jorda R.; MarÃa Zarate A.; Salas, C. O. Article ISI SCOPUS (2020)
NMR and Computational Studies on the Reactions of Enamines with Nitroalkenes That May Pass through Cyclobutanes Calafat, Jaume; Marco, Cristian Article ISI ACS OMEGA (2019)
Further Insight into the Interactions of the Cytotoxic Macrolides Laulimalide and Peloruside A with Their Common Binding Site Pineda, Oriol Article ISI ACS OMEGA (2018)
Further Insight into the Interactions of the Cytotoxic Macrolides Laulimalide and Peloruside A with Their Common Binding Site Alejandro Castro-Alvarez, Oriol Pineda Article ACS Omega (2018)
Mechanisms behind the enhancement of thermal properties of graphene nanofluids M. Rocio Rodríguez-Laguna, Alejandro Castro-Alvarez; Marianna Sledzinska, Jeremie Maire; Francesca Costanzo, Bernd Ensing; Miguel Pruneda, Pablo Ordejón; Clivia Sotomayor Torres, Pedro Gómez-Romero Article Nanoscale (2018)
Computer-Aided Insight into the Relative Stability of Enamines Article ISI SYNTHESIS-STUTTGART (2017)
The performance of several docking programs at reproducing protein–macrolide-like crystal structures Alejandro Castro-Alvarez, Anna M. Costa Article Molecules (2017)
Further insights into the organocatalytic reaction of 2,2-dimethyl-1,3-dioxan-5-one with alpha-silyloxy aldehydes Dani Sanchez, Hector Carneros; Alejandro Castro-Alvarez, Enric Llàcer; Ferran Planas, Jaume Vilarrasa Article Tetrahedron Letters (2016)
Importance of the electron correlation and dispersion corrections in calculations involving enamines, hemi-aminals, and aminals. Comparison of B3LYP, M06-2X, MP2, and CCSD results with experimental data Alejandro Castro-Alvarez, Dani Sanchez; Hector Carneros, Jaume Vilarrasa Article Journal of Organic Chemistry (2015)
How small amounts of impurities are sufficient to catalyze the interconversion of carbonyl compounds and iminium ions, or is there a metathesis through 1,3-oxazetidinium ions? Experiments, speculations, and calculations Dieter Seebach, Tomohiro Yoshinari; Albert K. Beck, Marc-Olivier Ebert; Alejandro Castro-Alvarez, Jaume Vilarrasa Article Helvetica Chimica Acta (2014)
Oxazolidinone/enamine ratios in the reactions of alpha-silyloxy and alpha-alkoxy aldehydes with proline Dani Sanchez, Alejandro Castro-Alvarez Article Tetrahedron Letters (2013)


Macrolidos como agentes antitumorales y antiviricos Ministerio de Economía y Competitividad (CTQ2012-39230) Proyecto 2012-2015 Tesista


Functionalizing Dendrimers for Targeted Delivery of Bioactive Molecules to Macrophages: A Potential Treatment for <i>Mycobacterium tuberculosis</i> Infection-A Review Review ISI PHARMACEUTICALS (2023)
Lanthanide SMMs Based on Belt Macrocycles: Recent Advances and General Trends Fuentealba, Pablo; Spodine, Evgenia; Aravena, Daniel Review ISI CHEMISTRY-A EUROPEAN JOURNAL (2022)
Structure, controlled release mechanisms and health benefits of pectins as an encapsulation material for bioactive food components Morales-Medina, Rocio; Drusch, Stephan; Benie, Astrid; Dragosavac, Marijana M.; Defain Tesoriero, Maria Victoria; Lowenstein, Patricia; Yonaha, Veronica; Iturralde, Ramiro; Peter, Regina Gauna Review ISI FOOD & FUNCTION (2022)