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Thomas Warwick Ledger Hermosilla

Associate Professor

UNIVERSIDAD ADOLFO IBÁÑEZ

Santiago, Chile

Líneas de Investigación


EVOLUTIONARY MICROBIOLOGY; MOLECULAR GENETICS; MICROBIAL MUTUALISTIC AND SYMBIOTIC INTERACTIONS; ENVIRONMENTAL MICROBIOLOGY

Educación

  •  Biological Sciences, Genetics and Microbiology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
  •  Biochemist, UNIVERSIDAD DE CHILE. Chile, 2003
  •  Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2000

Experiencia Académica

  •   Post Doctoral Researcher Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Facultad de Ciencias Biológicas

    Santiago, Chile

    2008 - 2009

  •   Post Doctoral Researcher Full Time

    UNIVERSIDAD ADOLFO IBANEZ

    Facultad de Ingeniería y Ciencias

    Santiago, Chile

    2009 - 2010

  •   Assistant Professor Full Time

    UNIVERSIDAD ADOLFO IBANEZ

    Facultad de Ingeniería y Ciencias

    Santiago, Chile

    2010 - 2017

  •   Associate Professor Full Time

    UNIVERSIDAD ADOLFO IBÁÑEZ

    Facultad de Ingeniería y Ciencias

    Santiago, Chile

    2017 - A la fecha

  •   Profesor Part Time

    UNIVERSIDAD SANTO TOMÁS

    Facultad de Biología

    Santiago, Chile

    2007 - 2009

Experiencia Profesional

  •   Professional Practice Other

    Universidad de Chile

    Santiago, Chile

    1999 - 1999

Formación de Capital Humano


In the last three years, I have directed 4 professional practices of engineering students specialized in bioengineering, 4 Master Theses in Biotechnology and Bioengineering. I have advised several biochemistry students in research seminars, and given general advisory for doctoral students in the bioengineering laboratory. Currently, I have sponsored 1 postdoctoral research work financed by Conicyt (finalized in 2016).

Teaching activities have involved 4 undergraduate courses a year for Bioengineering students, and a yearly participation in 2 postgraduate courses (Programa de Doctorado en Ingeniería de Sistemas Complejos, Universidad Adolfo Ibáñez). Seminars and short presentations for University and High School students have been carried out 4-5 times a year.


Difusión y Transferencia


Dissemination activities have included public and/or University conferences once a year. Technology transfer activities have been carried out in the form of applied projects for biostimulation and biofertilization of agricultural crops.


Premios y Distinciones

  •   Award for an Original Invention intended for a Patent Application

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2009

    Award Granted by OTRI Chile S. A., P. Universidad Católica de Chile.


 

Article (18)

The Arabidopsis holobiont: a (re)source of insights to understand the amazing world of plant-microbe interactions
Lac Operon Boolean Models: Dynamical Robustness and Alternative Improvements
The microbial community from the early-plant colonizer (Baccharis linearis) is required for plant establishment on copper mine tailings
Exploring the evolution of multicellularity in Saccharomyces cerevisiae under bacteria environment: An experimental phylogenetics approach
Non-halophilic endophytes associated to the euhalophyte Arthrocnemum macrostachyum and their plant growth promoting activity potential
Inferring bistable lac operen Boolean regulatory networks using evolutionary computation
Volatile-mediated effects predominate in paraburkholderia phytofirmans growth promotion and salt stress tolerance of Arabidopsis thaliana.
Burkholderia phytofirmans PsJN induces long-term metabolic and transcriptional changes involved in Arabidopsis thaliana salt tolerance
Quorum Sensing and Indole-3-Acetic Acid Degradation Play a Role in Colonization and Plant Growth Promotion of Arabidopsis thaliana by Burkholderia phytofirmans PsJN
Simultaneous assessment of the effects of an herbicide on the triad: rhizobacterial community, an herbicide degrading soil bacterium and their plant host
Aromatic compounds degradation plays a role in colonization of Arabidopsis thaliana and Acacia caven by Cupriavidus pinatubonensis JMP134
IncP-1 epsilon plasmids are important vectors of antibiotic resistance genes in agricultural systems: diversification driven by class 1 integron gene cassettes
The Complete Multipartite Genome Sequence of Cupriavidus necator JMP134, a Versatile Pollutant Degrader
3-Chlorobenzoate is taken up by a chromosomally encoded transport system in Cupriavidus necator JMP134
Chlorophenol hydroxylases encoded by plasmid pJP4 differentially contribute to chlorophenoxy acetic acid degradation
Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathways
Efficient turnover of chlorocatechols is essential for growth of Ralstonia eutropha JMP134(pJP4) in 3-chlorobenzoic acid
Novel insights into the interplay between peripheral reactions encoded by xyl genes and the chlorocatechol pathway encoded by tfd genes for the degradation of chlorobenzoates by Ralstonia eutropha JMP134

ConferencePoster (7)

Burkholderia phytofirmans PsJN regulates Arabidopsis growth through a signaling mechanism dependent of auxin and ethylene
Experimental phylogenies using yeasts: the role of bacterial environment on performance and morphology in experimental diversification
Exploring the microbiota associated to euhalophytes of the Salicornoideae family
Phytostimulation of drought stressed Arabidopsis by B. phytofirmans PsJN results from an interplay among contact-­dependent induction of stress tolerance and volatile-­‐‑mediated plant growth promotion
Arabidopsis thaliana growth and salinity tolerance induction by Burkholderia phytofirmans PsJN: Specific plant responses to bacterial emission of a blend of volatile signals
Burkholderia phytofirmans PsJN primes Arabidopsis thaliana plants to enhance salt-­‐‑stress tolerance
Increased tolerance to drought in Arabidopsis thaliana inoculated with Burkholderia phytofirmans PsJN: differential effects of colonization and the emission of volatile compounds.

Patent (1)

PGPR Compositions and Methods for Cultivation of Tomato and Potato Species

Proyecto (20)

Centro de Ecología Aplicada y Sustentabilidad-CAPES
Núcleo Milenio en Biología Sintética y Biología de Sistemas Vegetales
Papel de los factores sigma de función extracitoplasmática de la bacteria promotora del crecimiento Burkholderia phytofirmans PsJN en la colonización rizosférica y endofítica de plantas
Papel de los factores sigma de función extracitoplasmática de la bacteria promotora del crecimiento Burkholderia phytofirmans PsJN en la colonización rizosférica y endofítica de plantas
Influence of plant derived phenolic compounds on the ability of mutualistic proteobacteria to promote plant growth
Influence of plant derived phenolic compounds on the ability of mutualistic proteobacteria to promote plant growth.
Formulación y obtención de una mezcla definida de bacterias promotoras de crecimiento (PGPR) y su procedimiento de utilización durante el proceso de cultivo de las especies papa (Solanum tuberosum) y tomate (Solanum lycopersicum)
Fortalecimiento de la Investigación y la Docencia en Ciencias Biológicas Mediante la inserción de Investigadores Postdoctorales en Áreas Relevantes de la Bioingeniería
"Fortalecimiento de la investigación y la docencia en Ciencias Biológicas mediante la inserción de investigadores postdoctorales en áreas relevantes de la Bioingeniería".
Contribución de los plasmidios IncP-1 a la diversidad y adaptabilidad bacteriana
Effect of Burkholderia phytofirmans PsJN colonization on plant growth and resistance to abiotic stress
Effect of Burkholderia phytofirmans PsJN colonization on plant growth and resistance to abiotic stress.
Análisis de la expresión génica en el catabolismo de compuestos aromáticos y cloroaromáticos en el modelo bacteriano Cupriavidus necator, en cultivos líquidos y en microcosmos de suelos / planta
Núcleo Milenio en Ecología Microbiana y Microbiología y Biotecnología Ambiental EMBA
Interaccion entre el plasmidio catabolico pJP4 y el cromosoma de Ralstonia eutropha en la adaptacion y evolucion de vias del catabolismo de contaminantes cloroaromaticos en bacterias.
Interaccion entre el plasmidio catabolico pJP4 y el cromosoma de Ralstonia eutropha en la adaptacion y evolucion de vias del catabolismo de contaminantes cloroaromaticos en bacterias.
Expresión de genes microbianos involucrados en el catabolismo de compuestos aromáticos, lignina, y hemicelulosa, a nivel de laboratorio y en el ambiente
Regulacion de la Expresion y Actividad de las Integrinas por Estimulos Fisicos y Bioquimicos en Cultivos de Cardiomiocitos de Rata
Mejoramiento de las capacidades catabólicas hacia análogos clorados en microorganismos que degradan compuestos aromáticos, mediante transferencia de genes que codifican para enzimas de la degradación de clorocatecoles
Centro de Ecología Aplicada y Sustentabilidad (CAPES)
33
Thomas Ledger

Associate Professor

UNIVERSIDAD ADOLFO IBÁÑEZ

Santiago, Chile

15
Bernardo González

Full Professor

UNIVERSIDAD ADOLFO IBAÑEZ

Santiago, Chile

5
Danilo Pérez

Investigador

Programa Institucional de Fomento a la Investigación, Desarrollo e Innovación

UNIVERSIDAD TECNOLÓGICA METROPOLITANA

Santiago, Chile

4
María Poupin

Associate Professor, Academic Director of Executive Education

Facultad de Ingeniería y Ciencias

Universidad Adolfo Ibáñez

Santiago, Chile

2
Ana Zúñiga

postdoctoral research fellow

Centre de Biologie Structurale

Montpellier, Francia

2
Raúl Donoso

Investigador

PIDi

Universidad Tecnológica Metropolitana

Santiago, Chile

1
Marlene Manzano

Coordinador de Investigacion

Universidad Mayor

Santiago, Chile

1
Rodrigo Gutierrez

Full Professor

Molecular Genetics & Microbiology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Nicolas Guiliani

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Roberto Nespolo

Titular Professor

Instituto de Ciencias Ambientales y Evolutivas

Universidad Austral de Chile

Valdivia, Chile

1
Rodrigo De la Iglesia

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Nicole Trefault

Vicerrectora de Investigación

UNIVERSIDAD MAYOR

Santiago, Chile

1
Jaiber Solano

Investigador Senior

Departamento de Salud Hidrobiològica

Instituto de Fomento Pesquero

Puerto Montt, Chile

1
Julian Quintero

Investigador ICAEV

Instituto de Ciencias Ambientales y Evolutivas

Universidad Austral de Chile

Valdivia, Chile