Man

Nicolas Guiliani

Profesor Titular

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Microbiologia molecular y celular; Proteomica funcional; Metabolismo bacteriano; Quorum Sensing; c-di-GMP pathway; Biomiming microorganisms

Educación

  •  Microbiología, Université Aix-MArseille. Francia, 1996

Experiencia Académica

  •   Profesor Titular Full Time

    UNIVERSIDAD DE CHILE

    Ciencias

    Santiago, Chile

    2015 - A la fecha

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE CHILE

    Ciencias

    Santiago, Chile

    2009 - 2015

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Ciencias

    Santiago, Chile

    2003 - 2009

Formación de Capital Humano


He sido director de memoria de título (6), de tesis de magister (2) y de doctorado (6).
He sido co-director de tesis de magister (1) y de doctorado (2).



 

Article (30)

Quorum Sensing Signaling Molecules Positively Regulate c-di-GMP Effector PelD Encoding Gene and PEL Exopolysaccharide Biosynthesis in Extremophile Bacterium Acidithiobacillus thiooxidans
Does Bacterial Elasticity Affect Adhesion to Polymer Fibers?
Nucleotide Second Messenger-Based Signaling in Extreme Acidophiles of the Acidithiobacillus Species Complex: Partition Between the Core and Variable Gene Complements
The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase
Biofilm Formation by the Acidophile Bacterium Acidithiobacillus thiooxidans Involves c-di-GMP Pathway and Pel exopolysaccharide
Insights into the Quorum Sensing Regulon of the Acidophilic Acidithiobacillus ferrooxidans Revealed by Transcriptomic in the Presence of an Acyl Homoserine Lactone Superagonist Analog
Diguanylate Cyclase Null Mutant Reveals That C-Di-GMP Pathway Regulates the Motility and Adherence of the Extremophile Bacterium Acidithiobacillus caldus
Growth Inhibition of Bacterial Fish Pathogens and Quorum-Sensing Blocking by Bacteria Recovered from Chilean Salmonid Farms
Multiple antibiotic susceptibility of polyphosphate kinase mutants (ppk1 and ppk2) from Pseudomonas aeruginosa PAO1 as revealed by global phenotypic analysis
Biofilm formation, communication and interactions of leaching bacteria during colonization of pyrite and sulfur surfaces
AHL signaling molecules with a large acyl chain enhance biofilm formation on sulfur and metal sulfides by the bioleaching bacterium Acidithiobacillus ferrooxidans
Bioinformatic Prediction of Gene Functions Regulated by Quorum Sensing in the Bioleaching Bacterium Acidithiobacillus ferrooxidans
Quorum Sensing and Indole-3-Acetic Acid Degradation Play a Role in Colonization and Plant Growth Promotion of Arabidopsis thaliana by Burkholderia phytofirmans PsJN
The extremophile Acidithiobacillus ferrooxidans possesses a c-di-GMP signalling pathway that could play a significant role during bioleaching of minerals
Polyphosphate Synthesis as a Target for Novel Antibiotics
AHL communication is a widespread phenomenon in biomining bacteria and seems to be involved in mineral-adhesion efficiency
Identification of differentially expressed genes in an industrial bioleaching heap processing low-grade copper sulphide ore elucidated by RNA arbitrarily primed polymerase chain reaction
Molecular insights into quorum sensing in Acidithiobacillus ferrooxidans bacteria via molecular modelling of the transcriptional regulator AfeR and of the binding mode of long-chain acyl homoserine lactones
Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator
The chemolithoautotroph Acidithiobacillus ferrooxidans can survive under phosphate-limiting conditions by expressing a C-P lyase operon that allows it to grow on phosphonates
Evidence for a functional quorum-sensing type AI-1 system in the extremophilic bacterium Acidithiobacillus ferrooxidans
Differential protein expression during growth of Acidithiobacillus ferrooxidans on ferrous iron, sulfur compounds, or metal sulfides
Proteomic and genomic analysis of the phosphate starvation response of Acidithiobacillus ferrooxidans
An exported rhodanese-like protein is induced during growth of Acidithiobacillus ferrooxidans in metal sulfides and different sulfur compounds
The glycogen-bound polyphosphate kinase from Sulfolobus acidocaldarius is actually a glycogen synthase
Construction and characterization of a recA mutant of Thiobacillus ferrooxidans by marker exchange mutagenesis
Molecular cloning, sequencing, and expression of omp-40, the gene coding for the major outer membrane protein from the acidophilic bacterium Thiobacillus ferrooxidans
Characterization of an Operon Encoding Two c-Type Cytochromes, an aa3-Type Cytochrome Oxidase, and Rusticyanin in Thiobacillus ferrooxidansATCC 33020
Sequence and expression of the rusticyanin structural gene from Thiobacillus ferrooxidans ATCC33020 strain
Alanyl-tRNA synthetase gene of the extreme acidophilic chemolithoautotrophic Thiobacillus ferrooxidans is highly homologous to alaS genes from all living kingdoms but cannot be transcribed from its promoter in Escherichia coli

BookSection (2)

Cyclic di-GMP Signaling in Extreme Acidophilic Bacteria
Biofilm Formation by Acidophile Bacteria and Archaea

BookWhole (1)

Microbial Cyclic Di-Nucleotide Signaling

ConferencePaper (8)

Biofilm formation, communication and interactions of mesophilic leaching bacteria during pyrite oxidation
Characterization of the quorum sensing regulon in Acidithiobacillus ferrooxidans
Functional analysis of c-di-GMP pathway in biomining bacteria Acidithiobacillus thiooxidans
C-di-GMP pathway in biomining bacteria
C-di-GMP pathway in Acidithiobacillus ferrooxidans: analysis of putative diguanylate cyclases (DGCs) and phosphodiesterases (PDEs) bifunctional proteins
Differential genetic expression in heap bioleaching of low-grade copper sulphide ore at Escondida Mine, Chile
Is the quorum sensing type AI-1 system of Acidithiobacillus ferrooxidans involved in its attachment to mineral surfaces?
Proteomic studies in Acidthiobacillus ferrooxidans cells induced by synthetic acyl-homoserine lactones

Errata (1)

The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase (vol 10, 1499, 2019)

Proyecto (9)

DISSECTING C-DI-GMP NETWORKS AND BIOFILM ARCHITECTURE IN ACIDOPHILIC BACTERIA BELONGING TO THE NEW CLASS OF PROTEOBACTERIA ACIDITHIOBACILLIA
MODELLING AND OPTIMIZATION OF BIOFILM DEVELOPMENT ON METAL SULFIDES FOR INFLUENCING THEIR BIOLEACHING RATES
DEVELOPMENT AND EVALUATION OF NOVEL ANTI-MICROBIAL AGENTS BASED ON THE INHIBITION OF POLYPHOSPHATE SYNTHESIS IN OPPORTUNISTIC PATHOGENIC BACTERIA.
QUORUM SENSING SYSTEM AND C-DI-GMP PATHWAY IN BIOMINING BACTERIA (PART II)=> TIME FOR GENE SPECIFIC MUTAGENESIS, A CHALLENGING OUTLOOK.
Manipulation of Quorum Sensing systems in bioleaching bacteria=> Influences on biofilm formation and extracellular polymeric substances (EPS) production
Studies of the Quorum Sensing and its function during the bioleaching process in the bacterium Acidithio bacillus ferro oxidans. An interdisciplinary challenge at the chemical/biology/biothechnology frontier
"QUORUM SENSING" Y "C-DI-GMP PATHWAY" EN MICROORGANISMOS BIOMINEROS.
Studies of the inhibition of the afeI/afeR quorum sensing in the extremophile bacteria Acidithio bacillus ferro oxidans
ESTUDIO DEL "QUORUM SENSING" DE TIPO AL-1 MEDIADO POR EL PAR GENICO afeR/afel EN LA BACTERIA EXTREMOFILA ACIDOFILA ACIDITHIOBACILLUS FERROOXIDANS.

Review (1)

Genomics, metagenomics and proteomics in biomining microorganisms
41
Nicolas Guiliani

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

7
Lina Ruiz

Academico Docente Investigador

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

5
Mario Vera

Profesor Asistente

Instituto de Ingeniería Biológica y Medica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

5
Matías Castro

Investigador

Ingeniería y Tecnología

Universidad San Sebastián

Concepción, Chile

4
Alex Gonzalez

Profesor Asociado

Ciencias Biologicas

Universidad de los Lagos

Osorno, Chile

3
FRANCISCO REMONSELLEZ

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

3
Cecilia Demergasso

Directora

Centro de Biotecnología "Profesor Alberto Ruiz"

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

2
Felipe Galleguillos

Profesional

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

2
Pedro Galleguillos

Investigador

Centro de Investigación Científico y Tecnológico para la Minería

Antofagasta, Chile

2
Pedro Galleguillos

Investigador Titular

Minería

CICITEM

Antofagasta, Chile

2
SIMON BEARD

Investigador

Facultad de Medicina y Ciencia,

Universidad San Sebastián

Santiago, Chile

1
Paz Jopia

Investigador

Farmacia

Universidad de Valparaíso

Valparaíso, Chile

1
Raúl Donoso

Investigador postdoctoral

PIDi

Universidad Tecnológica Metropolitana

Santiago, Chile

1
Laura Tamayo

PROFESOR ASISTENTE

DEPARTAMENTO DE QUÍMICA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Víctor Zepeda

Investigador

Centro de Investigación Científico y Tecnológico para la Minería

Antofagasta, Chile

1
Claudio Miranda

Profesor Asociado

Departamento de Acuicultura

UNIVERSIDAD CATÓLICA DEL NORTE

Coquimbo, Chile

1
Francisco Chávez

Profesor Asistente

Departamento de Biología

Universidad de Chile

Santiago, Chile

1
Michael Seeger

Full Professor

Chemistry

UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

Valparaíso, Chile

1
Raquel Quatrini

Research Associate

Fundación Ciencia & Vida

Santiago, Chile

1
Sebastián Fuentes

Profesor asociado

Universidad Bernardo O'Higgins

Santiago, Chile

1
Francisco Melo

FULL PROFESSOR

FISICA

UNIVERSIDAD DE SANTIAGO DE CHILE

SANTIAGO, Chile

1
Sylvia Copaja

Profesor Asistente

Quimica

Universidad de Chile

Santiago, Chile

1
Homero Urrutia

Profesor titular

Facultad de Ciencias Biológicas

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Katherine Sossa

Associate professor

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

1
Gerardo Gonzalez

Full Professor

Microbiology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Alex Echeverría

Académico Adjunto

Centro de Investigación en Estudios Avanzados del Maule (CIEAM)

Universidad Católica del Maule

Talca, Chile

1
Ana Zúñiga

postdoctoral research fellow

Centre de Biologie Structurale

Montpellier, Francia

1
David Holmes

Head, Laboratory of Bioinformatics and Genome Biology

Center for Bioinformatics and Genome Biology

FUNDACION CIENCIA & VIDA

Santiago, Chile

1
pablo alviz

Unity chief

Laboratorio Hospital Regional de Copiapó

Servicio de Salud Atacama

copiapo, Chile

1
Matías Leal

Investigador Postdoctoral

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

1
Bernardo González

Full Professor

UNIVERSIDAD ADOLFO IBAÑEZ

Santiago, Chile

1
Rodrigo Gutierrez

Full Professor

Molecular Genetics & Microbiology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Thomas Ledger

Associate Professor

UNIVERSIDAD ADOLFO IBÁÑEZ

Santiago, Chile

1
María Poupin

Associate Professor, Academic Director of Executive Education

Facultad de Ingeniería y Ciencias

Universidad Adolfo Ibáñez

Santiago, Chile

1
Felipe Galleguillos

Director

Líneas nativas

Talca, Chile

1
Marcela Urzúa

Associate Professor

Chemistry

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Luis Hamm

Profesor Asociado

Física

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile