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Fernando Rodrigo Delgado Lopez

Associate Professor

Universidad Catolica del Maule

Talca, Chile

The overall goal of my research is to find further mechanistic explanations as to how Receptor Internalization and Degradation (RID) an adenoviral protein, blocks signaling triggered by TNF and LPS in human cancer and endothelial cells.

PhD, Albert Einstein College of Medicine. Estados Unidos, 2006
Master of Sciences, Albert Einstein Coillege of Medicine. Estados Unidos, 2002
Bioquimico, Universidad Austral de Chile. Chile, 1993

Visiting Scientist Full Time

Albert Einstein College of Medicine

Medicine

New York, Estados Unidos

1997 - 1999
Postdoctoral Research Associate Full Time

YALE UNIVERSITY

Health Sciences

New Heaven, Estados Unidos

2006 - 2007
Profesor Conferenciante Full Time

UNIVERSIDAD DE TALCA

Health Sciences

Talca, Chile

2011 - 2012
Profesor Asociado Full Time

Universidad Catolica del Maule

Medicine

Talca, Chile

2012 - At present
Postdoctoral Research Associate Full Time

Montefiore Medical Center

Medicine

New York, Estados Unidos

2007 - 2010

Laboratory Manager Full Time

Albert Einstein College of Medicine

New York, Estados Unidos

1997 - 2006
Research Fellow Full Time

Memorial Sloan Kettering Cancer Center

New York, Estados Unidos

1994 - 1997

Co-tutoring of doctoral thesis of

Joshua Friedman
Kathya Rekhman (MD-PhD)
Alex Leshokin
Adam Buntzman

Co-tutoring of training of:
Dr. Tsoline Kojaoghlanian (MD Fellow)

Currently mentoring Francisco Monsalve PhD student at Universidad de Talca
Currently in thesis committee of
Co-tutor of Ricardo Huilcaman at magister in biomedicine at Universidad de Talca

Lecturing to graduate and undergraduate students at Universidad de Talca and Universidad Catolica del Maule (courses of Pathophysiology, Molecular Medicine and Cell and Molecular Biology)

Young Investigator Award

Montefiore Medical Center

Estados Unidos, 2008

Award given by Montefiore on a yearly basis. There was an open competition where postdocs within the institution presented their work for evaluation. I was granted third place among the twenty Works compiting. My work was related to mapping and interaction of TEM8 in angiogénesis.


Breast Cancer and Environmental Contamination: A Real Connection? Delgado-Lopez, Fernando; Zamora-Leon, Sonia Article Cogent Medcine (2018)
HMGB1 enhances the protumoral activities of M2 macrophages by a RAGE-dependent mechanism Rojas A.; Delgado-Lopez, F; Perez-Castro R.; Gonzalez, I; Romero J.; Rojas I.; Araya, P; Añazco C.; Morales E. ; Llanos J. Article ISI SCOPUS TUMOR BIOLOGY (2016)
Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40-and Akt-dependent mechanism Puebla, C; Cisterna B.A.; Salas D.P.; Delgado-Lopez, F; Lampe P.D.; Sáez, J.C. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2016)
Tumor-associated macrophages in gastric cancer: more than bystanders in tumor microenvironment Rojas A.; Delgado-Lopez, F; Gonzalez, I Article SCOPUS Gastric Cancer (2016)
Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling Wernstedt Asterholm I, Tao C, Morley TS, Wang QA, Delgado-Lopez F, Wang ZV, Scherer PE. Article ISI SCOPUS CELL METABOLISM (2014)
Differential expression of two-pore domain potassium channels in rat cerebellar granule neurons Burgos P.; Zúñiga R.; Dominguez, P.; Delgado-Lopez, F; Plant, LD; Zuniga, L. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules Dalyot-Herman, Nava; Delgado-Lopez, Fernando; Gewirtz, David A.; Gupton, John T.; Schwartz, Edward L. Article ISI BIOCHEMICAL PHARMACOLOGY (2009)
Adenovirus RID alpha beta complex inhibits lipopolysaccharide signaling without altering TLR4 cell surface expression Delgado-Lopez, F; Horwitz, MS Article ISI JOURNAL OF VIROLOGY (2006)
Inhibition of chemokine expression by adenovirus early region three (E3) genes Lesokhin, AM; Delgado-Lopez, F; Horwitz, MS Article ISI JOURNAL OF VIROLOGY (2002)
Expression of Granulocyte-macrophage colony-stimulating factor receptors in human prostate cancer RIVAS, Coralia I.; Vera, Juan C.; Delgado-Lopez, Fernando; Heaney, Mark L.; Guaiquil, Victor H.; Zhang, Rong H.; Scher, HI; CONCHA, Ilona I.; Nualart, Francisco; Cordon-Cardo, Carlos; Golde, David W. Article ISI BLOOD (1998)
Hexose transporter expression and function in mammalian spermatozoa: Cellular localization and transport of hexoses and vitamin C Angulo, C; Rauch M.C.; Droppelmann A.; Reyes A.M.; Slebe J.C; Concha I.I.; Delgado-Lopez, F; Guaiquil V.H.; Vera, J. C. Article JOURNAL OF CELLULAR BIOCHEMISTRY (1998)
Expression of the fructose transporter GLUT5 in human breast cancer Zamora-Leon S.P.; Golde, D. W.; Rivas C.I.; Delgado-Lopez, F; Vera, J. C.; Baselga, J; Concha I.I.; Nualart, F. Article PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1996)
Nuclear Sm antigens in the sperm of different organisms Delgado, Fernando; Brito, Monica; Concha, Ilona; Schroeder, Ricardo; Burzio, Luis Article ISI ZYGOTE (1994)


Mechanisms of E3 modulation of immune and inflammatory responses Fessler, Shawn P.; Delgado-Lopez, Fernando; Horwitz, Marshall S. BookSection Medline (2004)


RAGE at tumor microenvironment. Looking at tumor-associated macrophages Delgado-Lopez, F; Rojas A. Editorial SCOPUS Chinese Journal of Lung Cancer (2015)


Skewed Signaling through the Receptor for Advanced Glycation End-Products Alters the Proinflammatory Profile of Tumor-Associated Macrophages Rojas A.; Araya P.; Romero J.; Delgado-LÃ³pez F.; Gonzalez I.; AÃ±azco C.; Perez-Castro R. Review ISI SCOPUS (2018)
Lysyl oxidase isoforms in gastric cancer Anazco, C; Delgado-Lopez, F; Araya, P; González, I; MORALES, E; Perez-Castro, R; romero, J; Rojas, A Review ISI SCOPUS BIOMARKERS IN MEDICINE (2016)
The Emerging Role of the Receptor for Advanced Glycation End Products on Innate Immunity Rojas A.; Perez-Castro, R; Gonzalez, I; Delgado F.; Romero J.; Rojas I. Review ISI INTERNATIONAL REVIEWS OF IMMUNOLOGY (2014)
Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases Monsalve, Francisco A.; Pyarasani, Radha D.; Delgado-Lopez, Fernando; Moore-Carrasco, Rodrigo Review ISI SCOPUS Mediators of Inflammation (2013)
The receptor for advanced glycation end-products: A complex signaling scenario for a promiscuous receptor Rojas A.; Delgado-Lopez, F; Gonzalez, I; Perez-Castro, R; Romero J.; Rojas I. Review ISI SCOPUS Cellular Signalling (2013)