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Wladimir Rodrigo Mardones Opazo

Investigador Joven

Instituto Milenio de Biología Integrativa

Santiago, Chile

Biodegradación de lignocelulosa; Genómica de hongos; Transcriptómica y Proteómica

Licenciado en Bioquímica, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2008
Doctorado en Biociencias Moleculares, UNIVERSIDAD ANDRES BELLO. Chile, 2015
Bioquímico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2009

Instructor Part Time

UNIVERSIDAD ANDRES BELLO

2010 - 2011
Instructor Ayudante Part Time

UNIVERSIDAD ANDRES BELLO

2013 - 2013
Profesor a Honorarios Part Time

UNIVERSIDAD DE SANTIAGO DE CHILE

2016 - At present

Profesor Laboratorio de Análisis Instrumental

Universidad Andrés Bello

Chile

2010 - 2010
Profesor Laboratorio de Análisis Instrumental

Universidad Andrés Bello

Chile

2011 - 2011
Ayudante

Universidad Andrés Bello

Chile

2013 - 2013
Posición Postdoctoral Full Time

Universidad de Santiago de Chile

Chile

2015 - 2017
Profesor a Honorarios

Universidad de Santiago de Chile

Chile

2016 - At present
Profesor a Honorarios Full Time

Universidad Andrés Bello

Santiago, Chile

2017 - At present
Posición Postdoctoral Full Time

Instituto Milenio de Biologia Integrativa (iBio)

Chile

2018 - 2019
Posición Postdoctoral Full Time

Universidad de Santiago de Chile

Chile

2019 - 2021
Posición Postdoctoral Full Time

Instituto Milenio de Biologia Integrativa (iBio)

Chile

2022 - 2023
Investigador Joven Full Time

Instituto Milenio de Biologia Integrativa (iBio)

Chile

2024 - At present

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Experimental Evolution and Hybridization Enhance the Fermentative Capacity of Wild Saccharomyces eubayanus Strains Article FEMS YEAST RESEARCH (2025)
Addition of<i> Saccharomyces</i><i> eubayanus</i> to SCOBY fermentations modulates the chemical and volatile compound profiles in kombucha Venegas, Camila A. Article ISI FOOD MICROBIOLOGY (2023)
Rapid selection response to ethanol in Saccharomyces eubayanus emulates the domestication process under brewing conditions Pena, Tomas A.; Nespolo, Roberto F.; Cubillos, Francisco A. Article ISI MICROBIAL BIOTECHNOLOGY (2022)
Fungal Diversity Analysis of Grape Musts from Central Valley-Chile and Characterization of Potential New Starter Cultures Mandakovic, Dinka; Pulgar, Rodrigo; Maldonado, Jonathan; Cubillos, Francisco A. Article ISI MICROORGANISMS (2020)
Molecular profiling of beer wort fermentation diversity across natural Saccharomyces eubayanus isolates Krogerus, Kristoffer; O'Donnell, Samuel; Minebois, Romain; Fischer, Gilles; Querol, Amparo; Gibson, Brian; Cubillos, Francisco A. Article ISI MICROBIAL BIOTECHNOLOGY (2020)
Corncob and sugar beet pulp induce specific sets of lignocellulolytic enzymes in Penicillium purpurogenum Mardones, W.; Callegari, E.; Eyzaguirre, J. Article MYCOLOGY (2018)
The genome sequence of the soft-rot fungus Penicillium purpurogenum reveals a high gene dosage for lignocellulolytic enzymes Mardones W.; CortÃ©s M.P. Article SCOPUS Mycology (2018)
Genomics Perspectives on Metabolism, Survival Strategies, and Biotechnological Applications of Brettanomyces bruxellensis LAMAP2480 Silva-Moreno, Evelyn; Mardones, Wladimir; Guzman, Darwin; Ganga, Angélica Article ISI SCOPUS JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Heterologous expression of a Penicillium purpurogenum exo-arabinanase in Pichia pastoris and its biochemical characterization Mardones W.; Callegari E.; Eyzaguirre, J Article ISI SCOPUS Fungal Biology (2015)
Characterization of a recombinant alpha-glucuronidase from Aspergillus fumigatus Rosa L.; Mardones W.; Eyzaguirre, J Article ISI SCOPUS Fungal Biology (2013)
Differential expression of genes from Penicillium purpurogenum when grown on sugar beet pulp and glucose as carbon sources Klagges, C.; Mardones W.; Eyzaguirre, J Article SCOPUS Mycology (2012)

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Cloning, sequencing, expression, and characterization of an alpha-glucuronidase from the fungus Aspergillus fumigatus Eyzaguirre, J; Rosa L.; Mardones W. Abstract ISI ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2012)
Penicillium purpurogenum secretes a bifunctional arabinofuranosidase (ABF3) Eyzaguirre, J; Rosa L.; Mardones W. Abstract ISI ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2011)

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EFFECT OF SEXUAL REPRODUCTION ON EVOLVING YEAST Proyecto (2024)
IDENTIFICATION OF THE MOLECULAR BASES OF ADAPTATION TO BREWING CONDITIONS OF NATIVE S. EUBAYANUS MARDONES OPAZO, WLADIMIR RODRIGO Proyecto (2019)
Instituto Milenio de Biología Integrativa de Sistemas y Sintética, iBio Iniciativa Cientifíca Milenio (iBio) Proyecto 2018-2018 Postdoctorado
Millennium Nucleus for Fungal Integrative and Synthetic Biology Iniciativa Cientifíca Milenio (FISB) Proyecto 2015-2016 Postdoctorado
ANALYSIS OF THE GENOME, TRANSCRIPTOME AND SECRETOME OF THE LIGNOCELLULOLYTIC FUNGUS PENICILLIUM PURPUROGENUM ALLOWS THE IDENTIFICATION OF ENZYMES RESPONSIBLE FOR THE BIODEGRADATION OF XYLAN AND PECTIN BY THE FUNGUS. FONDECYT (1130180) Proyecto 2013-2015 Tesista
THE SECRETOME OF PENICILLIUM PURPUROGENUM CONTAINS A LARGE SET OF XYLANOLYTIC AND PECTINOLYTIC ENZYMES. IDENTIFICATION, EXPRESSION AND CHARACTERIZATION OF THESE PROTEINS SHOULD PROVIDE VALUABLE INFORMATION ON THESE IMPORTANT BIODEGRADATION FONDECYT (1100084) Proyecto 2010-2013 Tesista
ANALISIS DEL SECRETOMA DEL HONGO PENICILLIUM PURPUROGENUM=> FUNCION Y PROPIEDADES DE LAS ENZIMAS QUE DEGRADAN EL XILANO . ¿PARA QUE PRODUCE NUMEROSAS ISOENZIMAS?. FONDECYT (1070368) Proyecto 2007-2010 Tesista