Generation and modulation of the respiratory rhythm; Central Chemoreception; Gliotransmission; Sudden Infant Death Syndrome; Biological Oscillators; Postnatal respiratory dysfunctions induced by prenatal exposure to drugs

GRADUATE THESIS DIRECTION
12 tutorships finished
• Infante C D. (2001), Ampuero E. (2002), Guzmán L (2006), Otárola M (2006), Mariqueo T. (2006), Beltrán S (2009), Bravo K (2011), González C (2012), Olivares M J (2014), and Irribarra E (2018) Licentiates in Biochemistry, Universidad de Santiago de Chile.
• Carrasco C (2006) Licentiate in Engineering Biotechnology, Universidad Tecnológica de Chile
1 co-tutorship finished
Saez JJ. (2008) Licentiate in Biology, Fac. Cs. Biológicas PUC (Tutor: Dr. R. von Bernhardi, PUC)

PhD THESIS TUTOR finished
2007 Cerpa V.J. PhD Program in Biological Sciences, mention Physiological Sciences, P.Univ. Católica de Chile.
2014 Beltrán S, PhD Program in Neuroscience, Universidad de Santiago de Chile
2014 Bravo E. PhD Program in Biotechnology, Universidad de Santiago de Chile
2015 Campos M. PhD Program in Biotechnology, Universidad de Santiago de Chile
2016 Bravo K, PhD Program in Neuroscience, Universidad de Santiago de Chile
2018 Oivares MJ, PhD Program in Neuroscience, Universidad de Santiago de Chile

POSTDOCTORATE
1999-01 Dr. Luis Constandil. Project “c-Fos expression in brainstem cholinergic neurons”
2007-08 Dr. Claudio Coddou. Project "Purinergic receptors as modulator of fictive respiration in neonates”.
Postdoctorate funding by Vice-rectory of Research and Development, Universidad de Santiago de Chile.
2016-17 Dr. Sebastián Beltran, Project USA 1498 y USA 1555 de la Universidad de Santiago de Chile
2018-19 Dr. María José Olivares, Project “Astrocytic D-serine and ATP interaction in the respiratory response to hipercapnia” (021843EL-postdoc)

TUTORIAL RESEARCH UNITS
Postgraduate
Since 2001 Tutor of Research Unit for 16 PhD students from PhD Programms: 1 Biological Sciences (PUC), 3 Biotechnology (USACH), 8 Neuroscience (USACH)
Undergraduate research units
Since 2001: 41 Medical students (Fac. Medical Sciences, USACH), 26 Biochemistry students (Fac. Chemistry and Biology, USACH), 1 Biology student, Fac. Biological Sciences, PUC, 2 Pharmaceutic Chemists (Fac. Chemistry and Biology USACH)

TEACHING IN POSTGRADUATE AND UNDERGRADUATE COLLECTIVE COURSES
Postgraduate
Director of the Projects of Creation of PhD Programs in Biotechnology (2002) and Neuroscience (2010)
Director of the PhD Program in Biotechnology USACH (2003-05)
Director of the PhD program in Neuroscience (2011-13) and (2016-present)

Responsible coordinator of Courses: “Topics in Biomedicine” (2003-16), PhD in Biotechnology, USACH; “Bibliographic Units I and II” (2011-present) Ph D in Neuroscience, USACH; “Systemic bases of Neuroscience” (2016-present), core course Ph D in Neuroscience, USACH.
Participation as teacher in multiple courses of PhD Programs in Biotechnology and Neuroscience (USACH) and invited professor in Neurobiological courses (Integrative Neurobiology, Sensory Biology) in ”, PhD in Biological Sciences, P. Universidad Católica de Chile, and in “Advanced Neurosciences”, PhD program in Biomedicine - Universidad de Chile
Professor in International Brain Research Organization (IBRO) “Visiting Lecture Programme”, Cuzco and Chiclayo (Perú), in the IX Latinoamerican School for Neuroscience (Escuela Latinoamericana de Neurociencias), IBRO, Santiago (Chile), and in the international course for postgraduate students: CURSO LATINOAMERICANO IBRO, “Biological Bases for the Nervous System Diseases”
Undergraduate Collective Courses
Since 1998, Responsible Teacher Course: Clinical Physiology, for Medical students, USACH; Multiple participation in Physiology courses for nursery, obstetrics, biochemistry, and physical education
Responsible Teacher for elective Course: Topics in Neuroscience, and participation in Courses of Physiological Chemistry and Biophysics for Biochemistry students, USACH

POSTGRADUATE COLLECTIVE COURSES
2002-04 Invited professor “Neurobiología integrativa”, PhD in Biological Sciences, P. Universidad Católica de Chile.
2003-09 Responsible Teacher, Course: Topics in Biomedicine, PhD programme in Biotechnology, USACH
2003-07 Teacher, Course: “Biological Process: from molecules to physiology”, PhD programme in Biotechnology, USACH
2003-10 Teacher, Course: Bibliographic Seminar I, PhD programme in Biotechnology, USACH.
2004 Invited professor “Neurobiología Sensorial (BIO-408)”, PhD in Biological Sciences, P. Universidad Católica de Chile.
2004 Teacher IX Latinoamerican School for Neuroscience (Escuela Latinoamericana de Neurociencias), IBRO, Santiago, Chile.
2005 Teacher, Course “Advanced Neurosciences”, PhD program on Neuroscience - Universidad de Chile.
2005 Teacher for the international course for postgraduate students: CURSO LATINOAMERICANO IBRO, “Biological Bases for the Nervous System Diseases” (Bases Biológicas de las Enfermedades del Sistema Nervioso).
2005-07 Invited profesor, Course: “Neurobiología”, PhD in Biological Sciences, P. Universidad Católica de Chile.

UNDERGRADUATE COLLECTIVE COURSES
1998-10 Responsible Teacher Course: Clinical Physiology, for Medical students, USACH
1997 Responsible Teacher Course: Topics in Neuroscience, for Biochemistry students, USACH
1995-04 Teacher Course: Physiology, for Nursery students, USACH
1995-06 Teacher Course: Physiology, for Obstetric students, USACH
2004-06 Teacher Course: Physiological Chemistry, for Biochemistry students, USACH
2005 Teacher Course: Physiology, for Licentiate in Physical Sciences, USACH
1995-08 Teacher Course: Animal Physiology, for Biochemistry students, USACH
2007-08 Teacher Course: Biohysics, for Biochemistry students, USACH

SELECTED INVITATIONS TO INTERNATIONAL COURSES (since 2002)
2002 Visiting Lecture Team Program IBRO, Cuzco, Perú.
2003 Visiting Lecture Team Program IBRO, Chiclayo, Perú.
2004 IX Latinoamerican School of Neuroscience, IBRO, Santiago-Valparaíso, Chile
2005 IBRO Latinoamerican Course: “Biological Basis of Nervous System Diseases”, Santiago, Chile
2013 Curso de Neurociencias avanzadas, Universidad de Sao Paulo, Riberao Pretto

SELECTED INVITATIONS TO INTERNATIONAL SIMPOSIA (since 2008)
2008 Discussion meeting, Brainstem: neural networks vital for life, The Royal Society, London Simposium: “Neural control of cardiorespiratory function”.
2012 First Congress of FALAN (Federation of societies of neuroscience of Latin America, the Caribbean and Iberian Peninsula), Cancún, México
2014 Simposium: “The Clinical Relevance of Cellular and Network Integration in Cardiorespiratory Control”, presentación de la ponencia: “Mechanism of neonatal respiratory rhythm dysfunction:
serotonin neurons as target of prenatal nicotine exposure”. First Panamerican Congress in Physiological Sciences, Foz de Iguazú, Brasil
2015 Conferencia: “Alteraciones serotoninérgicas por nicotina prenatal: implicancias para el sindrome de muerte súbita del lactante”. Primer Congreso Nacional e Internacional de la Academia de
Neurociencia del Perú, Lima, Perú.
2015 Conferencia: “Looking for mechanisms leading to the Sudden Infant Death Syndrome” Center for Integrative Research, Seattle Children’s Research Institute, Seattle, USA.
2016 Prof. John G. Nicholls celebration symposium: “Function, repair and training of the nervous system”. Second Congress of FALAN (Federation of societies of neuroscience of Latin America, the
Caribbean and Iberian Peninsula). The alteration of neonatal raphe neurons by prenatal-perinatal nicotine exposure. Meaning for Sudden Infant Death Syndrome
2019 "D-serine contributes to the respiratory response to hypercapnia"The 4th International Conference of D-Amino Acid Research (IDAR) that will take place in Tokyo in Japan from September 10 to
13,.2019

LECTURES AND SIMPOSIA IN CHILE (since 2014)
2014 Lecture: "Disfunción de la red neural respiratoria neonatal inducida por nicotina prenatal", Facultad de Ciencias Universidad de Valparaíso (10 octubre, Valparaíso).
2014 Lecture: "¿Es nicotina el nexo entre tabaquismo materno y muerte súbita del lactante?", Facultad de Medicina, Universidad Autónoma de Talca
2017 Lecture: “Astrocitos en el control neural respiratorio”, Seminario Depto Biología USACH.
2017 Lecture: “Astrocytic D-serine is a new player in the chemosensory control of breathing”, Symposium Glial cell-neuron Crosstalk in health and disease, XIII Annual Meeting Sociedad Chilena de
Neurociencia, Hotel de la Isla, Castro, Chile, October 1st 2017
2018 Lecture: "Bases neurobiológicas del Sindrome de Muerte Súbita del lactante" Simposio Actualizaciones en Psiquiatría y Neurología; de la ciencia básica a la cínica. Campus República,
Universidad Andrés Bello.

OUTREACH
2016 Guided visit to the laboratory and discussion about SIDS with 17 high school students form Colegio Municipal Santa María de Las Condes
2019 Lecture: "Comentarios de un creyente, católico practicante y neurocientífico sobre el libro “Las neuronas de Dios”
de Diego Golembek" in Seminar: “Neurocientíficos estudian fenómenos religiosos: ¿Un aval para la religiosidad? Universidad de Santiago, 8 abril 2019