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Francisca Alejandra Cornejo Castillo

Assistant professor

Universidad Mayor

Santiago, Chile

Neurosciences, Alzheimer's disease, glial cells, aging, autism spectrum disorders, neurodevelopmental diseases, neural precursor cells and gliogenesis

PhD in Medical Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2017
Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2011
Bs in Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009

Postdoc Full Time

UNIVERSIDAD ANDRES BELLO

Ciencias Biológicas

Santiago, Chile

2017 - 2018
Postdoc Full Time

UNIVERSIDAD MAYOR

Ciencias

Santiago, Chile

2018 - At present
Assistant professor Full Time

UNIVERSIDAD MAYOR

Santiago, Chile

2022 - At present

Teaching Assistant Part Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2009 - 2011
Research Assistant Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2011 - 2012
PhD Student Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2012 - 2017

Beca Doctorado Nacional

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2012

La Beca de Doctorado Nacional tiene por objeto apoyar financieramente los estudios de doctorado en todas las áreas del conocimiento, en programas acreditados en conformidad con la Ley Nº 20.129 e impartidos por universidades chilenas, por un plazo máximo de cuatro años, contados desde la fecha de inicio del programa de estudios, además, en caso que corresponda, una extensión de los beneficios de mantenimiento, hasta por un máximo de seis meses, para la redacción de la tesis doctoral.
Latin American Training Program

Society for Neuroscience

Estados Unidos, 2014

The Latin American Training Program (LATP) is a comprehensive, year-long online training program. It provides webinars, recorded content, and online discussions on cutting edge science and professional development to young investigators from Latin America and the Caribbean.
Postdoctorado Nacional

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2019

El objetivo de este concurso es estimular la productividad y liderazgo científico futuro de jóvenes investigadores(as) con grado académico de Doctor (según lo previsto en el numeral 2.1.1. de las presentes bases), mediante la realización de proyectos de investigación con miras a su inserción laboral en el ámbito académico u otro, a través de su incorporación en grupos de investigación consolidados que contribuirán a su desarrollo científico y que, a su vez, se verán fortalecidos por su participación. Los proyectos tendrán una duración de 2 o 3 años y el(la) Investigador(a) Responsable deberá tener dedicación exclusiva al trabajo de investigación.


Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex Cornejo, Francisca; Franchini, Nayhara; Cortes, Bastian I.; Elgueta, Daniela; Cancino, Gonzalo I. Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2024)
LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain Cornejo, F; Cortés, BI; Findlay, GM; Cancino, GI Article ISI, SCOPUS FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis Tomita, Hideaki; Cornejo, Francisca; Aranda-Pino, Begona; Woodard, Cameron L.; Rioseco, Constanza C.; Neel, Benjamin G.; Alvarez, Alejandra R.; Kaplan, David R.; Miller, Freda D.; Cancino, Gonzalo I Article ISI SCOPUS CELL REPORTS (2020)
The Role of the Rodent Insula in Anxiety Mendez-Ruette, M; Linsambarth, S; Moraga-Amaro, R; Quintana-Donoso, D; Mendez, L; Tamburini, G; Cornejo, F; Torres, RF; Stehberg, J Article ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2019)
Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimers disease pathophysiology Cornejo, F; Vruwink, M; Metz, C; Munoz, P; Salgado, N; Poblete, J; Andres, ME; Eugenin, J; von Bernhardi, R Article ISI SCOPUS BRAIN BEHAVIOR AND IMMUNITY (2018)
Age-Dependent Changes in the Activation and Regulation of Microglia Cornejo, F; von Bernhardi, R Article ISI SCOPUS GLIAL CELLS IN HEALTH AND DISEASE OF THE CNS (2016)
Expression Pattern of Scavenger Receptors and Amyloid-beta Phagocytosis of Astrocytes and Microglia in Culture are Modified by Acidosis: Implications for Alzheimer's Disease eugenin, j; Vecchiola, A; Murgas, P; Arroyo, P; Cornejo, F; von Bernhardi, R Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2016)
Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function Escobar, AP; Cornejo, FA; Olivares-Costa, M; Gonzalez, M.; Fuentealba, JA; Gysling, K; Espana, RA; Andres, ME Article ISI SCOPUS Journal of Neurochemistry (2015)
Role of TGF beta signaling in the pathogenesis of Alzheimer's disease von Bernhardi R.; Cornejo F.; Parada, GE; Eugenín J. Article ISI SCOPUS Frontiers in Cellular Neuroscience (2015)
SR-A Regulates the Inflammatory Activation of Astrocytes Murgas, P; Cornejo, FA; Merino, G; von Bernhardi R. Article ISI SCOPUS NEUROTOXICITY RESEARCH (2014)
Repeated treatment with the kappa opioid receptor agonist U69593 reverses enhanced K+ induced dopamine release in the nucleus accumbens, but not the expression of locomotor sensitization in amphetamine-sensitized rats Del Pilar Escobar A.; Cornejo F.A.; Andres, M. E.; Fuentealba J.A. Article ISI SCOPUS Neurochemistry International (2012)


EVALUATING THE ROLE OF PTPRD IN TAU PHOSPHORYLATION AND ALZHEIMER'S DISEASE PATHOLOGY Cornejo, Francisca Proyecto (2022)
THE ROLE OF THE ASD-RELATED GENE PTPRD IN GLIOGENESIS DURING CORTICAL BRAIN DEVELOPMENT Cornejo, Francisca Proyecto (2019)
THE IMPACT OF THE TYROSINE PHOSPHATASE PTPRD IN NEURAL STEM CELL BIOLOGY AND ITS CONTRIBUTION TO AUTISM SPECTRUM DISORDER ETIOLOGY Cancino, Gonzalo I Proyecto (2016)
THE IMPACT OF THE TYROSINE PHOSPHATASE PTPRD IN NEURAL STEM CELL BIOLOGY AND ITS CONTRIBUTION TO AUTISM SPECTRUM DISORDER ETIOLOGY FONDECYT (1161374) Proyecto 2016-2020 Personal técnico y/o de apoyo
THE ROLE OF THE INSULA IN ANXIETY AND IN ANXIETY-RELATED DISORDERS IN THE RAT Stehberg, Jimmy R. Proyecto (2016)
THE ROLE OF THE INSULA IN ANXIETY AND IN ANXIETY-RELATED DISORDERS IN THE RAT. FONDECYT (1160986) Proyecto 2016-2020 Personal técnico y/o de apoyo
PARTICIPATION OF SCAVENGER RECEPTOR A IN THE INFLAMMATORY ACTIVATION OF GLIAL CELLS=> A POTENTIAL TARGET FOR THERAPEUTIC INTERVENTION IN ALZHEIMERS DISEASE Bernhardi M., Rommy von Proyecto (2013)
PARTICIPATION OF SCAVENGER RECEPTOR A IN THE INFLAMMATORY ACTIVATION OF GLIAL CELLS=> A POTENTIAL TARGET FOR THERAPEUTIC INTERVENTION IN ALZHEIMERS DISEASE. FONDECYT (1131025) Proyecto 2013-2017 Tesista
MOLECULAR AND NEUROCHEMICAL DYSFUNCTIONS IN AN ANIMAL MODEL OF OBSESSIVE-COMPULSIVE DISORDER FONDECYT (1110352) Proyecto 2011-2015 Personal técnico y/o de apoyo
MOLECULAR AND NEUROCHEMICAL DYSFUNCTIONS IN AN ANIMAL MODEL OF OBSESSIVECOMPULSIVE DISORDER Andrés, Maria Estela Proyecto (2011)
BIOCHEMICAL AND CELLULAR MECHANISMS REGULATING NURR1-DEPENDENT TRANSCRIPTIONAL ACTIVITY Andrés, Maria Estela Proyecto (2007)
BIOCHEMICAL AND CELLULAR MECHANISMS REGULATING NURR1-DEPENDENT TRANSCRIPTIONAL ACTIVITY. FONDECYT (1070349) Proyecto 2007-2011 Tesista


Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer's Disease Cornejo F.; von Bernhardi R. Review ISI SCOPUS Mediators of Inflammation (2013)