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Fernando Andres Ortiz Cisternas

profesor asistente

Universidad de Santiago de Chile

Santiago, Chile

Demyelinating diseases; Neuroinflammation; Myelin synthesis and repair; Glia-neuron and glia-glia interaction, Pathophysiology of astrocytes and oligodendrocytes precursor cells. Vagal nerve stimulation

Licenciatura en Cs Mn Biologia, UNIVERSIDAD DE CHILE. Chile, 2005
Magister en Cs Fisiologicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Doctorado en Cs Biologicas Mn Cs Fisiologicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2011

profesor asistente Full Time

UNIVERSIDAD AUTONOMA DE CHILE

Ciencias de la Salud

Santiago, Chile

2017 - 2022
profesor encargado, curso Morfofisiología Part Time

UNIVERSIDAD CENTRAL DE CHILE

Educación

Santiago, Chile

2011 - 2011
Instructor, curso Fisiologia Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2011 - 2011
profesor, curso fisiologia oral Part Time

UNIVERSIDAD AUTONOMA DE CHILE

Santiago, Chile

2011 - 2011
profesor, curso Neurobiología Full Time

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2009 - 2011
Instructor, curso Fisiologia Part Time

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

2009 - 2010
Instructor, curso Biofisica y fisiologia general Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biologicas

Santiago, Chile

2008 - 2008
Instructor, curso Fisiologia de sistemas Other

UNIVERSIDAD DE CHILE

Ciencias

Santiago, Chile

2005 - 2009
Investigador Postdoctoral Full Time

Universidad Paris Sorbona, Paris-V

Medicina

Paris, Francia

2014 - 2016
Investigador Part Time

NATIONAL INSTITUTE OF HEALTH

Bethesda, Estados Unidos

2013 - 2013
Becario Postdoctoral Full Time

Universidad Paris Sorbona, Paris-V

Medicina

Paris, Francia

2011 - 2014
Estudiante doctorado Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biologicas

Santiago, Chile

2006 - 2011
Asistente tecnico, proyecto FONDECYT 1090157 Part Time

UNIVERSIDAD DE CHILE

Ciencias

Santiago, Chile

2010 - 2011
Asistente tecnico, proyecto FONDECYT 1040638 Part Time

UNIVERSIDAD DE CHILE

Ciencias

Santiago, Chile

2006 - 2007
Assistant professor Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Chemistry and Biology

Chile

2023 - At present

Assistant Professor Full Time

Universidad Autonoma de Chile

Chile

2017 - 2022
Assitant professor Full Time

Universidad de Santiago de Chile

Chile

2023 - At present

THESIS AND INTERNSHIP DIRECTION

2019- To date. PhD Thesis Direction. PhD program on Biomedical Sciences, Universidad Autónoma de Chile.
Student: Coram Guevara.
Subject: Role of astrocytic cytokines on remyelination.

2018- To date. PhD Thesis Direction. PhD program on Biomedical Sciences, Universidad Autónoma de Chile.
Student: Sebastian Vejar.
Subject: Astrocyte-oligodendrocyte interaction on myelin metabolic supply to axon under demyelinated conditions.

2019- To date. Internship. School of Medicine, Universidad Autónoma de Chile.
Student: Andres Munoz.
Subject: Setting a new model of multiple sclerosis: demyelinated lesions in cerebellum,
Funded by ‘UA-Scientific Initiation Fellowship’.

2018 Internship. María García- Blanes Martínez, Biochemist, Universidad Autónoma de Madrid.
Subject: Immunohistochemistry and confocal imaging of glial in demyelinated lesions.

2018 Profesional Practice. Pontificia Universidad Católica de Valparaíso.
Student: Sebastian Vejar, Biochemist.
Subject: Setting a station for electrophysiological recordings, electrophysiological characterization of glial cells.

2017-2018 Internship. School of Medicine, Universidad Autónoma de Chile.
Student: Benjamin Suarez Camus.
Subject: Immunohistochemistry and electrophysiological characterization of demyelinated lesions
Funded by ‘UA-Scientific Initiation Fellowship’.

2014-2015 M. Sc . Thesis Co-Direction.
Student: Pierre-Yves Houry.
Thesis: Role of the Neuronal Activity on the oligodendroglia during the remyelination of corpus callosum.
Master Biologie et Santé-signalisation cellulaire-neuroscience, Paris Sud University.

2013-2014 M. Sc . Thesis Co-Direction.
Student: Nour Barça.
Thesis: Expression of NMDA receptor-mediated currents of oligodendrocyte precursor cells during early postnatal development and following demyelination of the mouse corpus callosum.
Master II recherche de science et technologie Mention Biologie intégrative et physiologie, Spécialité neurosciences. Paris Descartes University.

PARTICIPATION IN EXAMINING COMMITTEES

-2019. Undergraduate thesis. External examiner.
Student: Felipe Alvarez
Thesis: Estudio de efectos de trauma agudo sobre astrocitos del hipocampo en ratones de 2 meses de edad
Biochemistry. P. Universidad Catolica de Chile (in progress)

-2019. PhD thesis. External examiner.
Student: Amber Philp,
Tthesis: The Role of Platelets in Remyelination of the Central Nervous System.
PhD in Medical Sciences program. Universidad Austral de Chile (in progress)

-2018. MSc thesis. External examiner.
Student: Diego Becerra,
Thesis: Olfactory pattern separation in behaving mice.
Master in Biological Sciences program. Universidad de Chile (graduate in December 2019)

-2018. PhD thesis. Internal Member.
Student: Carola Tapia,
Thesis: Contribución del poro de transición de permeabilidad mitocondrial al daño mitocondrial y alteraciones sinápticas inducidas por la proteína tau clivada por caspasa 3.
PhD in Biomedical Sciences program. Universidad Autonoma de Chile (in progress)

-2018. PhD thesis. Internal Member.
Student: Camilo Toledo
Thesis: Rol del nucleo retrotrapezoide en el Desarrollo de alteraciones cardiorespiratorias en insuficiencia cardiaca.
PhD in Biomedical Sciences program. Universidad Autónoma de Chile (graduate in July 2018)

OUTREACH ACTIVITIES

-Scientific content creator developing audovisual products for scientific divulgation. Associated with Samuel Restucci (cartoonist-cinema director) we are creating short-animated movies and virtual reality educational environments for divulgation.
https://www.youtube.com/watch?v=0nV_Ck7k-8U&feature=emb_title

-Scientific content creator developing books for scientific divulgation to adolescents. Associated with the center of scientific communication, Universidad Autónoma de Chile.
https://ciencias.uautonoma.cl/relatos-de-tu-conciencia/
.
-Internships in the Myelin Laboratory. We have created a program for short-internships of high school students in our laboratory. The associated schools belong to the metropolitan area.
https://myelin-lab.cl/divulgacion/

- Member of “Fundación Chile Hace Ciencia”. Nonprofit organization aiming to scientific divulgation. I participate as a scientific content collaborator, presenting seminars and organizing products for divulgation (i.e. currently we are preparing a book for high school students)
https://chilehaceciencia.wordpress.com/

Travel Award

CONICYT

Chile, 2008

It cover the expenses to attend the ISAC international meeting at Valladolid, Spain
Travel Award

CONICYT

Chile, 2009

It cover the expenses to attend the SfN meeting at Chicago, USA
Travel Award

VRAID-PUC

Chile, 2010

It cover the expenses to attend the SfN meeting at San Diego, USA
Best Oral Communication

ARSEP (French Society for Multiple Sclerosis)

Francia, 2015

Best Oral Communication in the Annual Meeting on Multiple Sclerosis, ARSEP Foundation, Paris.
Best Poster presentation

ARSEP (French Society for Multiple Sclerosis)

Chile, 2014

Best poster presentation in the Annual Meeting on Multiple Sclerosis, ARSEP Foundation, Paris.


A preclinical mice model of multiple sclerosis based on the toxin-induced double-site demyelination of callosal and cerebellar fibers Vejar, Sebastian; Pizarro, Ignacio S.; Pulgar-Sepulveda, Raul; Vicencio, Sinay C.; Polit, Andres; Amador, Cristian A.; del Rio, Rodrigo; Varas, Rodrigo; Orellana, Juan A.; Ortiz, Fernando C. Article ISI BIOLOGICAL RESEARCH (2024)
Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage Gomez, Gonzalo I.; Alvear, Tanhia F.; Roa, Daniela A.; Farias-Pasten, Arantza; Vergara, Sergio A.; Mellado, Luis A.; Martinez-Araya, Claudio J.; Prieto-Villalobos, Juan; Garcia-Rodriguez, Claudia; Sanchez, Natalia; Saez, Juan C.; Ortiz, Fernando C.; Orellana, Juan A. Article ISI BIOLOGICAL RESEARCH (2024)
Evidence for TGF-β1/Nrf2 Signaling Crosstalk in a Cuprizone Model of Multiple Sclerosis. Guevara C, Vicencio SC, Pizarro IS, Villavicencio-Tejo F, Quintanilla RA, Astudillo P, Ampuero E, Varas R, Orellana JA, Ortiz FC Article WOS ANTIOXIDANTS (2024)
A New Bioassay for the Detection of Paralytic and Amnesic Biotoxins Based on Motor Behavior Impairments of Zebrafish Larvae de la Paz, Javiera F. F.; Zambrano, Nicolas O.; Ortiz, Fernando O. C.; Llanos-Rivera, Alejandra Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Cardiovascular and autonomic dysfunction in long-COVID syndrome and the potential role of non-invasive therapeutic strategies on cardiovascular outcomes Allendes, Francisca J.; Diaz, Hugo S.; Ortiz, Fernando C.; Marcus, Noah J.; Quintanilla, Rodrigo; Inestrosa, Nibaldo C.; Del Rio, Rodrigo Article ISI FRONTIERS IN MEDICINE (2023)
Lipid-Encapsuled Grape Tannins Prevent Oxidative-Stress-Induced Neuronal Cell Death, Intracellular ROS Accumulation and Inflammation Diaz, Hugo S.; Rios-Gallardo, Angelica; Ortolani, Domiziana; Diaz-Jara, Esteban; Jose Flores, Maria; Vera, Ignacio; Monasterio, Angela; Ortiz, Fernando C.; Brossard, Natalia; Osorio, Fernando; Del Rio, Rodrigo Article ISI ANTIOXIDANTS (2022)
Potential Role of the Retrotrapezoid Nucleus in Mediating Cardio-Respiratory Dysfunction in Heart Failure With Preserved Ejection Fraction. Toledo, Camilo; Ortolani, D; Ortiz, FC; Marcus, NJ; Del Rio, Rodrigo Article FRONTIERS IN PHYSIOLOGY (2022)
Sleep dysregulation in sympathetic-mediated diseases: implications for disease progression Olivares MJ; Toledo, Camilo; Ortolani, D; Ortiz, FC; Diaz, HS; Iturriaga R; del Rio, Rodrigo Article SLEEP (2022)
Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure Schwarz, Karla G.; Pereyra, Katherin, V; Toledo, Camilo; Andrade, David C.; Diaz, Hugo S.; Diaz-Jara, Esteban; Ortolani, Domiziana; Rios-Gallardo, Angelica; Arias, Paulina; Las Heras, Alexandra; Vera, Ignacio; Ortiz, Fernando C.; Inestrosa, Nibaldo C.; Vio, Carlos P.; Del Rio, Rodrigo Article ISI BIOLOGICAL RESEARCH (2021)
Exercise intolerance in volume overload heart failure is associated with low carotid body mediated chemoreflex drive Andrade, David C.; Diaz-Jara, Esteban; Toledo, Camilo; Schwarz, Karla G.; Pereyra, Katherin V.; Diaz, Hugo S.; Marcus, Noah J.; Ortiz, Fernando C.; Rios-Gallardo, Angelica P.; Ortolani, Domiziana; Del Rio, Rodrigo Article ISI SCIENTIFIC REPORTS (2021)
Exercise training reduces brainstem oxidative stress and restores normal breathing function in heart failure Diaz-Jara, Esteban; Diaz, Hugo S.; Rios-Gallardo, Angelica; Ortolani, Domiziana; Andrade, David C.; Toledo, Camilo; V. Pereyra, Katherin; Schwarz, Karla; Ramirez, Gigliola; Ortiz, Fernando C.; Andia, Marcelo E.; Del Rio, Rodrigo Article ISI FREE RADICAL BIOLOGY AND MEDICINE (2021)
Glial-derived transforming growth factor β1 (TGF-β1): a key factor in multiple sclerosis neuroinflammation Guevara, C; Ortiz, FC Article NEURAL REGENERATION RESEARCH (2021)
Heart rate and cardiac autonomic responses to concomitant deep breathing, hand grip exercise, and circulatory occlusion in healthy young adult men and women Andrade, David C.; Melipillan, Claudia; Toledo, Camilo; Rios-Gallardo, Angelica; Marcus, Noah J.; Ortiz, Fernando C.; Martinez, Gonzalo; Munoz Venturelli, Paula; Del Rio, Rodrigo Article ISI SCIELO BIOLOGICAL RESEARCH (2021)
Paraquat herbicide diminishes chemoreflex sensitivity, induces cardiac autonomic imbalance and impair cardiac function in rats Pereyra, Katherin, V; Schwarz, Karla G.; Andrade, David C.; Toledo, Camilo; Rios-Gallardo, Angelica; Diaz-Jara, Esteban; Bastias, Sussy S.; Ortiz, Fernando C.; Ortolani, Domiziana; Del Rio, Rodrigo Article ISI AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2021)
Pannexin 1-based channels activity as a novel regulator of multiple sclerosis progression Ortiz, FC; Puebla, C Article ISI SCOPUS NEURAL REGENERATION RESEARCH (2020)
Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species Saez, Juan C.; Vargas, Anibal A.; Hernandez, Diego E.; Ortiz, Fernando C.; Giaume, Christian; Orellana, Juan A. Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Connexin and Pannexin-Based Channels in Oligodendrocytes: Implications in Brain Health and Disease Vejar, Sebastián; Oyarzún, Juan E.; Retamal, Mauricio A; Ortiz, Fernando C.; Orellana, Juan A. Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Neuronal activity in vivo enhances functional myelin repair Ortiz F.C.; Habermacher C.; Graciarena M.; Houry P.-Y.; Nishiyama A.; Oumesmar B.N.; Angulo M.C. Article ISI SCOPUS JCI INSIGHT (2019)
Carotid Body Type-I Cells Under Chronic Sustained Hypoxia: Focus on Metabolism and Membrane Excitability Pulgar-Sepúlveda, R; Varas, R; Iturriaga, R; Del Rio, R; Ortiz, F.C. Article ISI FRONTIERS IN PHYSIOLOGY (2018)
Carotid Body Type-I Cells Under Chronic Sustained Hypoxia=> Focus on Metabolism and Membrane Excitability. Pulgar-Sepúlveda, Raúl; Varas, Rodrigo; Iturriaga, Rodrigo; Del Rio, Rodrigo; Ortiz, Fernando C Article Frontiers in physiology (2018)
In vivo optogenetic approach to study neuron-oligodendroglia interactions in mouse pups Ortolani D.; Manot-Saillet B.; Orduz D.; Ortiz F.C.; Angulo M.C. Article ISI SCOPUS Frontiers in Cellular Neuroscience (2018)
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain Remaud, S; Ortiz, FC; Perret-Jeanneret, M; Aigrot, MS; Gothie, JD; Fekete, C; Kvarta-Papp, Z; Gereben, B; Langui, D; Lubetzki, C; Angulo, MC; Zalc, B; Demeneix, B Article ELIFE (2017)
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain Remaud, S; Ortiz, FC; Perret-Jeanneret, M; Aigrot, MS; Gothie, JD; Fekete, C; Kvarta-Papp, Z; Gereben, B; Langui, D; Lubetzki, C; Angulo, MC; Zalc, B; Demeneix, B Article ELIFE (2017)
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain Remaud, S; Ortiz, FC; Perret-Jeanneret, M; Aigrot, MS; Gothie, JD; Fekete, C; Kvarta-Papp, Z; Gereben, B; Langui, D; Lubetzki, C; Angulo, MC; Zalc, B; Demeneix, B Article ISI ELIFE (2017)
A commentary on: "Anti-muscarinic adjunct therapy accelerates functional human oligodendrocyte repair" Ortiz, Fernando C.; Balia, Maddalena; Orduz, David Article ISI FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Alteration of synaptic connectivity of oligodendrocyte precursor cells following demyelination Sahel, Aurelia; Ortiz, Fernando C.; Kerninon, Christophe; Maldonado, Paloma P.; Angulo, Maria Cecilia; Nait-Oumesmar, Brahim Article ISI FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons Wake, Hiroaki; Ortiz, Fernando C.; Woo, Dong Ho; Lee, Philip R.; Angulo, Maria Cecilia; Fields, R. Douglas Article ISI NATURE COMMUNICATIONS (2015)
Micromolar copper modifies electrical properties and spontaneous discharges of nodose ganglion neurons in vitro Ortiz, FC; Vergara C., Alcayaga J. Article BIOMETALS (2014)
Micromolar copper modifies electrical properties and spontaneous discharges of nodose ganglion neurons in vitro. Ortiz, Fernando C; Vergara, Cecilia; Alcayaga, Julio Article Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine (2014)
Inhibition of rat carotid body glomus cells TASK-like channels by acute hypoxia is enhanced by chronic intermittent hypoxia Ortiz, FC; Del Rio R., Ebensperger G.; Reyes, VR; Alcayaga J., Varas; R., Iturriaga R. Article Respiratory Physiology and Neurobiology (2013)
Inhibition of rat carotid body glomus cells TASK-like channels by acute hypoxia is enhanced by chronic intermittent hypoxia. Ortiz, Fernando C; Del Rio, Rodrigo; Ebensperger, German; Reyes, Victor R; Alcayaga, Julio; Varas, Rodrigo; Iturriaga, Rodrigo Article Respiratory physiology & neurobiology (2013)
Contribution of TASK-Like Potassium Channels to the Enhanced Rat Carotid Body Responsiveness to Hypoxia Ortiz, FC; Del Rio R., Varas; R., Iturriaga R. Article Advances in Experimental Medicine and Biology (2012)
Contribution of TASK-like potassium channels to the enhanced rat carotid body responsiveness to hypoxia. Ortiz, Fernando C; Del Rio, Rodrigo; Varas, Rodrigo; Iturriaga, Rodrigo Article Advances in experimental medicine and biology (2012)
Functional expression of the alpha 7 and alpha 4-containing nicotinic acetylcholine receptors on the neonatal rat carotid body Meza R.C.; Ortiz, F.C.; Bravo, E.; Iturriaga-Vasquez, P; Eugenin, J.L.; Varas, R. Article ISI SCOPUS NEUROCHEMISTRY INTERNATIONAL (2012)
Muscarinic modulation of TASK-like background potassium channel in rat carotid body chemoreceptor cells Ortiz, FC; Varas, R. Article Brain Research (2010)
Muscarinic modulation of TASK-like background potassium channel in rat carotid body chemoreceptor cells. Ortiz, Fernando C; Varas, Rodrigo Article Brain research (2010)
Responses induced by acetylcholine and ATP in the rabbit petrosal ganglion Soto, CR; Ortiz, FC; Vargas, RV; Arroyo, J. Article Respiratory Physiology and Neurobiology (2010)
Responses induced by acetylcholine and ATP in the rabbit petrosal ganglion. Soto, Carolina R; Ortiz, Fernando C; Vargas, Romina V; Arroyo, Jorge; Alcayaga, Julio Article Respiratory physiology & neurobiology (2010)
Sustained hypoxia enhances TASK-like current inhibition by acute hypoxia in rat carotid body type-I cells. Ortiz, F; Iturriaga, R; Varas, R Article Advances in experimental medicine and biology (2009)
Carotid body transmitters actions on rabbit petrosal ganglion in vitro Alcayaga, Y; Soto, CR; Vargas, RV; Ortiz, FC; Arroyo, J. Article Advances in Experimental Medicine and Biology (2006)
Carotid body transmitters actions on rabbit petrosal ganglion in vitro. Alcayaga, Julio; Soto, Carolina R; Vargas, Romina V; Ortiz, Fernando C; Arroyo, Jorge; Iturriaga, Rodrigo Article Advances in experimental medicine and biology (2006)


Caracterización de las vías colinérgicas del troncoencéfalo en las etapas desmielinizantes de un modelo murino de esclerosis múltiple , Daniza Del Carmen Vicencio Sandoval; Vejar, Sebastián; Guevara, C; Reyes, Javier; Varas, Rodrigo; Ortiz, FC ConferencePoster (2022)
Impact of Vagal Nerve Stimulation on the progression of demyelinated lesions in a murine model of Multiple sclerosis Vejar, Sebastián; sepulveda raul; Guevara, C; Vicencio S.; Del Rio R.; Varas, Rodrigo; Ortiz, FC ConferencePoster (2022)
Efecto de la estimulación vagal sobre la remielinización en un modelo murino de EM MuÑoz A.; Vejar, S; Varas, Rodrigo; Ortiz, FC ConferencePoster (2021)
Rol de los canales formados por panexina-1 en la progression de lesiones desmielinizantes Pulgar-Sepulveda, R; Vejar, Sebastián; Puebla, Carlos; Ortiz, FC ConferencePoster (2021)
Contribution of Reactive Astrocytes to Myelin Repair Carrillo-de Sauvage MA, Pulgar-Sepúlveda R., Vejar S, Flament J, Escartin C, Ortiz FC ConferencePoster (2019)
Dissecting the Contribution of Reactive Astrocytes to Myelin Repair Pulgar-Sepúlveda R., Carrillo-de Sauvage MA, Vejar S, Flament J, Escartin C, Ortiz FC ConferencePoster (2019)
Effect of Astrocytes Photo-activation on Remyelination in Freely Moving Mice Vejar S, Habermacher C, Guevara C, Pulgar-Sepúlveda R, Angulo MC, Varas R, Ortiz FC ConferencePoster (2019)
Exploring the Contribution of Reactive Astrocytes to Myelin Repair Pulgar-Sepúlveda R., Carrillo-de Sauvage MA, Vejar S, Flament J, Escartin C, Ortiz FC ConferencePoster (2019)
Focal Demyelination in the Cerebellum: a Preclinical Model for the Study of Multiple Sclerosis Guevara C, Muñoz A, Nuñez A, Pulgar-Sepúlveda R, Cea LA, Andrade D, Toledo C, Del Rio R, Ortiz FC ConferencePoster (2019)
Alpha–linolenic acid decreases the myogenic differentiation of c2c12 cells Gomez G, Avendaño B, Ortiz FC, Puebla C. ConferencePoster (2018)
An in vivo optogenetic approach to study neuron-oligodendroglia interactions in mouse pups Ortolani D, Manot-Saillet B, Ortiz FC, Angulo MC ConferencePoster (2018)
Dissecting astrocyte- activity contribution to myelin repair García-Blanes M, Pulgar-Sepúlveda R, Vejar S, Suarez B, Varas R, Ortiz FC ConferencePoster (2018)
Effect of astrocyte activity on axon-oligodendroglia glutamatergic transmission Vejar S, Pulgar-Sepúlveda R, Varas R, Ortiz FC ConferencePoster (2018)
Effects of astrocyte activity on axon-OPC glutamatergic transmission, Pulgar-Sepúlveda R, Vejar S, Varas R, Ortiz FC ConferencePoster (2018)
Effects of astrocyte activity on myelin regeneration Pulgar-Sepúlveda R, García-Blanes M, Vejar S, Suarez B, Varas R, Ortiz FC ConferencePoster (2018)
Increased neuronal activity on remyelination Habermacher C, Ortiz FC, Houry PY, Graciarena M., Nait-Oumesmar B., Angulo MC ConferencePoster (2018)
Effect of increased neuronal activity on remyelination in freely moving mice Habermacher C, Ortiz FC, Houry PY, Graciarena M., Nait-Oumesmar B., Angulo MC ConferencePoster (2017)
Improved remyelination by increasing neuronal activity in freely moving mice Ortiz FC, Habermacher C, Houry PY, Lopez C, Graciarena M., Nait-Oumesmar B., Angulo MC ConferencePoster (2017)
Improved remyelination by increasing neuronal activity in freely moving mice Ortiz FC, Habermacher C, Houry PY, Lopez C, Graciarena M., Nait-Oumesmar B., Angulo MC ConferencePoster (2017)
Increased neuronal activity on remyelination in freely moving mice Ortiz FC, Habermacher C, Houry PY, Graciarena M., Nait-Oumesmar B., Angulo MC ConferencePoster (2017)
An optogenetic approach to evaluate activity-dependent remyelination Ortiz FC, Houry PY, Angulo MC ConferencePoster (2015)
An optogenetic approach to evaluate the effect of neuronal activity on remyelination Ortiz FC, Habermacher C, Houry PY, Angulo MC ConferencePoster (2015)
Impact of Gabaergic activity on cortical oligodendrogenesis Ortolani D, Ortiz FC, Orduz D, Angulo MC ConferencePoster (2015)
Is remyelination dependent on neuronal activity? Ortiz FC ConferencePoster (2015)
Alterations of synaptic connectivity of oligodendrocyte progenitor cells following central nervous system demyelination Ortiz FC, Sahel A, Kerninon C, Audinat E, Maldonado PP, Angulo MC, Nait Oumesmar B ConferencePoster (2014)
Non-synaptic junctions on myelinating glia promote preferential myelination of electrically-active axons Fields RD, Wake H, Ortiz FC, Lee PR, Angulo MC ConferencePoster (2014)
Regulation of glutamatergic transmission in myelin repair Ortiz FC, Gracianera M, Barça N, Nait Oumesmar B, Angulo MC ConferencePoster (2014)
Alterations of NG2 cell synaptic connectivity following demyelination of corpus callosum Ortiz FC, Sahel A, Kerninon C, Maldonado PP, Angulo MC, Nait Oumesmar B. ConferencePoster (2013)
Influences of Neuronal-NG2 cell synapses on myelin Sahel A, Ortiz FC, Maldonado PP, Kerninon C, Angulo MC, NaitOumesmar B. ConferencePoster (2012)
Chronic intermittent hypoxia increases the inhibition of TASK-like current and the depolarization evoked by acute hypoxia in rat CB type-I cells Ortiz FC, Alcayaga J, Varas R, Iturriaga R ConferencePoster (2011)
Contribution of the Carotid Body to the Cardiorespiratory alterations induced by intermittent hypoxia Iturriaga, R. Del Rio R, Moya E.A, Ortiz FC, Alcayaga J ConferencePoster (2011)
Electrophysiological evidence of two hyperpolarization- activated inward currents in petrosal ganglion neurons Boncompte G, Ortiz FC, Alcayaga J. ConferencePoster (2011)
Activation of α7 and α4β2 nicotinic acetylcholine receptor regulates catecholamine release in the rat carotid body Meza RC, Ortiz FC, Iturriaga-Vásquez P, Varas R ConferencePoster (2010)
Functional expression of a hypoxia sensitive TASK-like potassium channel in adult rat carotid body type-1 cells Ortiz FC, Del Rio R, Varas R, Iturriaga R ConferencePoster (2010)
Functional expression of an oxygen-sensitive TASK-like background K+ channel in the adult rat carotid body type-I cells Ortiz FC, Del Rio R, Iturriaga R, Varas R ConferencePoster (2010)
The role of the TASK-like background potassium channel in carotid body function Varas R, Ortiz FC ConferencePoster (2010)
Muscarinic acetylcholine receptor activation inhibits TASK-likeK+ current in rat carotid body chemoreceptor cells Ortiz FC, Varas R ConferencePoster (2009)
Chronic hypoxia enhanced the TASK-like current inhibition evoked by acute hypoxia in rat carotid body Ortiz FC, Varas R, Iturriaga R ConferencePoster (2008)
Evidences for regulation by external acidosis of nicotinic acetylcholine receptors in rat chemoreceptor cells Ortiz FC, Varas R, Iturriaga R ConferencePoster (2008)
Sustained hypoxia potentiates the inhibitory effect of acute hypoxia on TASK-like potassium current in carotid body chemoreceptor cells Ortiz FC, Varas R, Iturriaga R ConferencePoster (2008)
La hipoxia crónica potencia la inhibicion de la corriente tipo TASK evocada por hipoxia aguda Ortiz FC, Varas R, Iturriaga R ConferencePoster (2007)
Efecto del cobre sobre las propiedades eléctricas de neuronas nodosas de conejo Ortiz FC, Vergara C, Alcayaga J ConferencePoster (2006)
El cobre modifica la excitabilidad de neuronas del ganglio nodoso de conejo Ortiz FC, Vergara C, Alcayaga J ConferencePoster (2006)
Electrophysiological characterization of rabbit petrosal and nodose ganglion neurons Ortiz, FC; Alcayaga, J ConferencePoster (2006)
Carotid body transmitters actions on rabbit petrosal ganglion in vitro Soto CR, Vargas RV, Ortiz FC, Arroyo J, Iturriaga R, Alcayaga J ConferencePoster (2005)
Propiedades eléctricas de neuronas de ganglios petrosos y nodosos de conejo, poster session Ortiz FC, Alcayaga J ConferencePoster (2005)
Serotonin induced responses in the rabbit petrosal ganlion in vitro, poster session Alcayaga J, Soto CR, Vargas RV, Ortiz FC, Arroyo J ConferencePoster (2005)
Efecto de serotonina sobre la frecuencia de descarga del nervio carotideo de conejo Soto CR, Vargas RV, Ortiz FC, Arroyo J, Mateluna C, Muñoz DB, Alcayaga J ConferencePoster (2004)


Editorial: Physiology of Myelin Forming Cells, From Myelination to Neural Modulators Baraban M.; Retamal M.A.; Ortiz F.C. Editorial ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2019)


ASTROCYTIC CYTOKINE SIGNALING IN MULTIPLE SCLEROSIS: A NOVEL TARGET TO REDUCE DISEASE PROGRESSION Ortiz FC Proyecto (2022)
Astrocytic cytokine signaling in multiple sclerosis: implications in disease progression Ortiz, Fernando C. Proyecto (2021)
Vagal nerve stimulation: a new approach to treat MS Varas, Rodrigo; Ortiz, FC Proyecto (2021)
Multi-Target Drug Design Against Neurodegenerative Diseases Ramirez, David Proyecto (2020)
Role of myelination and oligodendroglia development on chronic social defeat stress Ortiz, Fernando C.; Graciarena, Mariana Proyecto (2020)
CENTRAL ROLE OF ASTROCYTES IN NEURONAL-DRIVEN REMYELINATION PCI (ECOS180013) Proyecto 2019-2021 Inv. Responsable
Cortical myelination in a murine autistic model Graciarena, Mariana Proyecto (2019)
Efecto de la foto-activación de astrocitos sobre la diferenciación de oligodendrocitos en lesiones desmielinizadas. VRIP Universidad Autonoma de Chile (DIUA127-2018) Proyecto 2018-2019 Inv. Principal
Manipulation of astrocyte reactivity in demyelinated lesions) PCI (REDI170037) Proyecto 2018-2019 Inv. Responsable
Role of reactive astrocytes at the different stages of remyelination in an in vivo model of multiple sclerosis NeurATRIS-EATRIS (EU) (Neuratris_00) Proyecto 2018-2020 Inv. Responsable
Role of reactive astrocytes at the different stages of remyelination in an in vivo model of multiple sclerosis NeurATRIS (“translational research infrastructure for innovative therapies in Neuroscience-EU/France”) (ANR-11-INBS-0011) Proyecto 2018-2020 Inv. Responsable
Manipulación de la reactividad de astrocitos en lesiones desmielinizantes PCI (REDI170037) Proyecto 2017-2019 Inv. Responsable
ROLE OF ASTROCYTES IN THE REMYELINATION OF THE CORPUS CALLOSUM IN A MODEL OF MULTIPLE SCLEROSIS-LESIONS FONDECYT (11160616) Proyecto 2016-2019 Inv. Responsable
Regulation of myelin repair by glutamatergic transmission between axons and NG2 cells ARSEP (Fondation pour l'aide à la recherche sur la sclérose en plaques) (no aplica) Proyecto 2014-2014 Investigador(a)
Synaptic control of NG2 cell fate during myelination and myelin repair in white matter ANR blanche (France) (no aplica) Proyecto 2011-2014 Investigador(a)
CONTRIBUTION OF THE CAROTID BODY TO THE HYPERTENSION INDUCED BY INTERMITTENT HYPOXIA IN A RAT MODEL OF SLEEP APNEA=> ROLE OF THE SYMPATHETIC SYSTEM, OXIDATIVE STRESS AND PRO-INFLAMMATORY CYTOKINES. FONDECYT (1100405) Proyecto 2010-2014 Personal técnico y/o de apoyo
PARTICIPATION OF PETROSAL GANGLION NEURONS IN THE INCREASED CHEMOREFLEX SENSIBILTY DURING HYPOXIC VENTILATORY ACCLIMATIZATION. FONDECYT (1090157) Proyecto 2009-2012 Personal técnico y/o de apoyo
CONSECUENCIAS FISIOPATOLOGICAS DE LA HIPOXIA INTERMITENTE CRONICA SOBRE LA QUIMIORRECEPCION CAROTIDEA Y LA REGULACION CARDIORESPIRATORIA. FONDECYT (1070584) Proyecto 2007-2010 Personal técnico y/o de apoyo
CARACTERIZACION ELECTROFISIOLOGICA Y FARMACOLOGICA DE LOS RECEPTORES INVOLUCRADOS EN LA GENERACION DE LA ACTIVIDAD AFERENTE QUIMIOSENSORIAL ARTERIAL EN NEURONAS PETROSAS. FONDECYT (1040638) Proyecto 2004-2008 Personal técnico y/o de apoyo


Neuroinflammation in Demyelinating Diseases: Oxidative Stress as a Modulator of Glial Cross-Talk Varas R.; Ortiz F.C. Review ISI SCOPUS CURRENT PHARMACEUTICAL DESIGN (2019)