
Mauricio Antonio Retamal Lucero
Associate Professor
Universidad del Desarrollo
Santiago, Chile
Study of the molecular mechanisms of opening and closing of the channels formed by connexins. And the study of hemichannels in various cellular functions under physiological and pathological conditions.
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Bachelor of Science / Biology, UNIVERSIDAD DE CHILE. Chile, 2000
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PhD in Physiology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005
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Associate Professsor Full Time
Universidad del Desarrollo
Medicina
santiago, Chile
2008 - At present
Postdoctoral Tutor training of Dr. Rodrigo Acuña. 2016-2020.
Tutor of PhD student. Ms Fernanda Rozas. 2016-present.
Tutor of PhD student Ms Viviana Orellana. 2017-present.
Tutor of PhD student Ms Ainoa Fernandez. 2019-present.
Classes in General Physiology for Medicine - UDD
Classes of Advanced Topics in Physiology - DICIM
Class on cellular communication in Biomedical Sciences - U. Autónoma
In all these courses, I have told students about connexins, hemichannels, cleft junctions, and lab results.
In 2018, I participated in the science week of the Alianza Francesa school, Chamisero headquarters. On that occasion, during one morning I talked to kindergarteners about science and also did a series of basic experiments on chemistry and physics.
Also during 2018, I gave several interviews to electronic newspapers and radio and TV programs, about the role of Cx46 in diseases such as cancer.
https://m.elmostrador.cl/agenda-pais/vida-en-linea/vida-destacados/2019/01/10/estudio-podria-ayudar-adetener-metastasis-en-mujeres-con-cancer-de- mama / https://www.duna.cl/programa/aire-fresco/2019/01/10/programa-de-comunicacion-celular-en-cancer-udd-quebusca-mejorar-la-eficacia-de-los- current-treatments / http://biut.latercera.com/salud/2019/01/expertos-descubren-tratamiento-que-podria-disminuir-los-efectos-delcancer-de-mama/ https: //www.24horas. cl / videos / interviews24 / Chilean-study-could-help-stop-the-metastasis-of-breast-cancer-3058983 https://www.pauta.cl/ciencia-y-tecnologia/avanza-estudio-que -seeks-to-stop-metastasis-in-women-with-breast-cancer
- Also during 2018 and 2019 I participated in the Biology Study group 2 in ANID.
Finally, during the months of July and October 2019, with a group of 5 girls from Boston College La Farfana School in the Maipú commune, we did experiments in my laboratory on the effect of Chilote garlic and different types of paprika on the death of cancer cells in mom. They learned from cell culture to doing cell death experiments on a Nikon microscope. They found that a chilote garlic extract induces cell death even when the extract was highly diluted.
Dopamine inhibits ATP-induced responses in the cat petrosal ganglion in vitro (vol 966, pg 283, 2003) |
The C-terminal of Cx46 modulates the phosphorylation of Akt1 through protein-protein interactions. |
CARBON MONOXIDE INHIBITS CX46 HCS THROUGH A LIPID PEROXIDATION-DEPENDENT PROCESS WHICH INCREASES CX46- CA2+ SENSITIVITY |
Carbon monoxide inhibits Cx46 HCs through a lipid peroxidation-dependent process, which increases Cx46- Ca2+ sensitivity |
CARDIORESPIRATORY IMBALANCE IN HIGHT-OUTPUT HEART FAILURE: DISTINCT ROLES FOR THE CENTRAL PRE-SYMPATHETIC NEURONS AND THE PERIPHERAL CAROTID CHEMORECEPTORS IN THE PROGRESSION OF THE DISEASE |
CARDIORESPIRATORY IMBALANCE IN HIGHT-OUTPUT HEART FAILURE=> DISTINCT ROLES FOR THE CENTRAL PRE-SYMPATHETIC NEURONS AND THE PERIPHERAL CAROTID CHEMORECEPTORS IN THE PROGRESSION OF THE DISEASE |
Estudio de vías de señalización intracelulares activadas por ácidos grasos omega-3 y sus efectos en el estado funcional de Hemicanales formados por Cxs del Cristalino |
UNSATURATED FATTY ACIDS CHANGE CX43, CX46 AND CX50 HEMICHANNELS PROPERTIES INDUCING LENS CELLS DAMAGE. |
Sensor de Voltaje de Canales de Iones=> Desde la Estructura a la Función |
Unsaturated fatty acids change Cx43, Cx46 and Cx50 hemichannels properties inducing lens cells damage |
NITRIC OXIDE INDUCES FUNCTIONAL AND STRUCTURAL MODIFICATIONS IN CX46 GAP-JUNCTION HEMICHANNELS AND CHANNELS. |
NITRIC OXIDE INDUCES FUNCTIONAL AND STRUCTURAL MODIFICATIONS IN CX46 GAP-JUNCTION HEMICHANNELS AND CHANNELS. |
PROGRAMA BECAS DE APOYO PARA LA REALIZACION DE TESIS DOCTORAL |
Beca Doctorado - Conicyt |
PROGRAMA NACIONAL DE BECAS DE POSTGRADO - DOCTORADO |
Sensor de Voltage de Canales de Iones: Desde la Estructura a la Función |

Mauricio Retamal
Associate Professor
Programa de Comunicación Celular en Cancer
Universidad del Desarrollo
Santiago, Chile

Juan Orellana
Associate Professor
Departamento de Neurología
PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE
Santiago, Chile

Julio Alcayaga
Profesor Titular
Biología
UNIVERSIDAD DE CHILE, FAC. CIENCIAS, DEPTO. BIOLOGÍA
Santiago, Chile

Rodrigo Del Rio
Assistant Professor
Physiology
Pontificia Universidad Católica de Chile
Santiago, Chile

Vania Figueroa
Directora InES Género y CTGénero, Coordinadora de Vinculación de Investigación Aplicada
Centro de Comunicación de las Ciencias
Universidad Autónoma de Chile
Santiago, Chile

Claudia Lucero
Asistente Investigación-Docente
Instituto de Ciencias Biomédicas
Universidad Autónoma de Chile
Santiago, Chile

Rodrigo Iturriaga
Chairman of the Department of Physiology
Physiology
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Santiago, Chile

Rodrigo Moraga
Postdoctoral researcher
Nuklear Medizin
Medizinische Hochschule Hannover
Hannover, Alemania

Agustin Martinez
Profesor Titular
Instituto de Neurociencia
UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO
Valparaíso, Chile

Fernando Ortiz
profesor asistente
Departmento de Biología, Facultad de Quimica y Biología
Universidad de Santiago de Chile
Santiago, Chile

Ivan Alfaro
Associate Professor, Director of Innovation and Technology Development
Faculty of Medicine
Universidad del Desarrollo
Santiago, Chile

Carolina Oliva
Investigadora y Coordinadora Áreas STEM
Vicerrectoría de Investigación y Doctorados
Universidad Autónoma de Chile
Santiago, Chile

Fernando Ezquer
Full Professor
Center for Regenerative Medicine
Universidad del Desarrollo
Santiago, Chile

Carlos Manuel González
DIRECTOR ESCUELA
FACULTAD CIENCIAS DE LA VIDA
UNIVERSIDAD ANDRES BELLO
SANTIAGO, Chile

Eduardo Ezquer
Director/Full Professor
Centro de Medicina Regenerativa
UNIVERSIDAD DEL DESARROLLO, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS
Santiago, Chile

Felipe Simon
Profesor Titular
Department of Biological Sciences
UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS
Santiago, Chile

Andrés Tittarelli
Profesor Asociado
Instituto Universitario de Investigación y Desarrollo Tecnológico (IDT)
Universidad Tecnológica Metropolitana
Santiago, Chile

Pablo Vial
Professor
School of Medicine
ICIM/UNIVERSIDAD DEL DESARROLLO - CLÍNICA ALEMANA
Santiago, Chile

Wendy Gonzalez
Director of the Center for Bioinformatics, Simulations and Modeling (CBSM)
Bioinformática
CENTRO DE BIOINFORMÁTICA Y SIMULACIÓN MOLECULAR (CBSM)/ UNIVERSIDAD DE TALCA
Talca, Chile