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Juan Esteban Oyarzún Isamitt

Investigador postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

1. Efectos del estrógeno sobre el desarrollo del hígado graso no alcohólico 2. Efectos de extractos derivados del polen apícola en el desarrollo del hígado graso no alcohólico 3. Análisis del hígado graso no alcohólico por resonancia magnética

Investigación Clínica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2019
Biólogo, mención Bioprocesos, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012

Ayudante Bioquímica y Genética Molecular Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Bilógicas

Santiago, Chile

2010 - 2012
Ayudante del ramo Procesos Biológicos Básicos de Enfermedades Humanas Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

santiago, Chile

2017 - 2017

Investigador Full Time

Empresa biotecnológica Virobay Inc.

Santiago, Chile

2013 - 2013
Investigador Postdoctoral Full Time

Pontificia Universidad Católica de Chile

santiago, Chile

2019 - At present


Hepatoprotective species from the Chilean medicinal flora: Junellia spathulata (Verbenaceae) Bridi, Raquel; Lino von Poser, Gilsane; Gómez, Miguel; Andia, Marcelo E; Oyarzún, Juan Esteban; Núñez, Paula; Vasquez Arias, Ariadsna Jael; Espinosa-Bustos, Christian Article Journal of Ethnopharmacology (2021)
Honeybee Pollen Extracts Reduce Oxidative Stress and Steatosis in Hepatic Cells Oyarzún, Juan Esteban; Andia, Marcelo E; Uribe, Sergio; Núñez Pizarro, Paula; Núñez, Gabriel; Montenegro, Gloria; Bridi, Raquel Article MOLECULES (2021)
Connexin 43 hemichannels and pannexin-1 channels contribute to the alpha-synuclein-induced dysfunction and death of astrocytes Díaz, Esteban F.; Labra, Valeria C.; Alvear, Tanhia F.; Mellado, Luis A.; Inostroza, Carla A.; Oyarzún, Juan E.; Salgado, Nicole; Quintanilla, Rodrigo A.; Orellana, Juan A. Article ISI SCOPUS GLIA (2019)
Connexin and Pannexin-Based Channels in Oligodendrocytes: Implications in Brain Health and Disease Vejar, Sebastián; Oyarzún, Juan E.; Retamal, Mauricio A; Ortiz, Fernando C.; Orellana, Juan A. Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
The Opening of Connexin 43 Hemichannels Alters Hippocampal Astrocyte Function and Neuronal Survival in Prenatally LPS-Exposed Adult Offspring ChÃ¡vez C.E.; OyarzÃºn J.E.; AvendaÃ±o B.C.; Mellado L.A.; Inostroza C.A.; Alvear T.F.; Orellana J.A. Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Gadolinium chloride rescues Niemann–Pick type C liver damage Klein A.D.; OyarzÃºn J.E.; Cortez C.; Zanlungo S. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Heavy Alcohol Exposure Activates Astroglial Hemichannels and Pannexons in the Hippocampus of Adolescent Rats: Effects on Neuroinflammation and Astrocyte Arborization Gómez, Gonzalo I.; Falcon, Romina V.; Maturana, Carola J.; Labra, Valeria C.; Salgado, Nicole; Rojas, Consuelo A.; Oyarzun, Juan E.; Cerpa, Waldo; Quintanilla, Rodrigo A.; Orellana, Juan A. Article ISI SCOPUS Frontiers in Cellular Neuroscience (2018)
Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer Graumann R.; Capua G.A.D.; Oyarzún J.E.; Vásquez M.A.; Liao C.; Brañes J.A.; Roa I.; Casanello P.; Corvalán A.H.; Owen G.I.; Delgado I.; Zangemeister-Wittke U.; Ziegler A. Article ISI SCOPUS PLOS ONE (2017)
Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis Contreras O.; Rebolledo D.L.; Oyarzún J.E.; Olguín H.C.; Brandan, E. Article ISI SCOPUS CELL AND TISSUE RESEARCH (2016)


Searching for Common Pathogenic Pathways leading to Neuronal and Hepatic Damage in Niemann-Pick Diseases. FONDECYT (1150186) Proyecto 2015-2018 Tesista
Efficacy of the cathepsin B inhibitor VBY-376 for treatment of liver disease in the mouse model of Niemann-Pick type C disease Empresa biotecnológica Virobay Inc. Proyecto 2013-2013 Personal técnico y/o de apoyo
Exploring new pathophysiological pathways in nonalcoholic fatty liver disease FONDECYT (1110455) Proyecto 2011-2015 Personal técnico y/o de apoyo


Lysosome motility and distribution: Relevance in health and disease OyarzÃºn J.E.; Lagos J.; VÃ¡zquez M.C.; Valls C.; De la Fuente C.; Yuseff M.I.; Alvarez A.R.; Zanlungo S. Review ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)