
Fernando Eduardo Ezquer Romero
Full Professor
Universidad del Desarrollo
Santiago, Chile
Regenerative Medicine, Mesenchymal Stem Cells, Induced Pluripotent Stem Cells, Animal Models, Diabetes Mellitus, Alcoholism, Addictions
-
Cell Biology, Molecular Biology and Neuroscience, UNIVERSIDAD DE CHILE. Chile, 2006
-
Molecular Biologist, Universidad Nacional de San Luis. Argentina, 2001
-
Associate Professor Full Time
Universidad del Desarrollo
Medicine
Santiago, Chile
2006 - 2020
-
Full Professor Full Time
Universidad del Desarrollo
Medicine
Santiago, Chile
2020 - At present
-
Vice-Director Center for Regenerative Medicine Full Time
Universidad del Desarrollo
Santiago, Chile
2016 - At present
Human Capital Training
Undergraduate Thesis
Karla Leal Villegas, Biotecnology, Faculty of Agricultural and Forestry Sciences, Universidad de la Frontera. Finished 2014 (Role: Director)
Scarlet Montecino Villalobos, Biochemist, Faculty of Sciences, Pontificia Universidad Catolica de Valparaiso. Finished 2015 (Role: Director)
Katheryne Gonzalez Bravo, Medical Technology, Universidad Pedro de Valdivia. Finished 2018 (Role: Director)
Diego Díaz Gomez, Biochemist, Faculty of Sciences, Pontifícia Universidad Católica de Valparaiso. Finished 2019 (Role: Director)
María Constanza Cárcamo Aguilera, Biochemist, Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile. Finished 2020 (Role: Director)
Esteban Ariel Rodríguez Sanhueza, Biochemist, Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile. Finished 2021 (Role: Director)
Carolina Ponce, Biotecnology, Faculty of Agricultural and Forestry Sciences, Universidad de la Frontera. Finished 2021 (Role: Director)
Master Thesis
Martina Redel Villaroel. Master in Neuroscience. Faculty of Medicine. Universidad de Chile. Finished 2021. (Role: Co-Director).
PhD Thesis
Andrea Tapia Bustos, PhD in Pharmacology, Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile. Finished 2020 (Role: Co-Director)
José Luis Ordoñes Belmar, PhD in Pharmaceutical Sciences, Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile. Under developing (Role: Co-Director)
Alba Avila. PhD in Science and Innovation in Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo. Under developiung (Role: Director).
Mauricio Quezada Diez. PhD in Science and Innovation in Medicine, Faculty of Medicine Clínica Alemana-Universidad del Desarrollo. Under developing (Role: Director).
Marta Catalina Zamorano Cataldo. PhD in Pharmacology. Faculty of Medicine. Universidad del Desarrollo. Under developing (Role: Co-Director).
Invention patents associated with Biopharmaceuticals
Ezquer M, Ezquer F. Pattent Application N°201502971 (5/10/2015). Biopharmacological composition that comprises components produced and / or secreted by mesenchymal stem cells (MSC) that allow to recover the tissue regenerative capacity, in a situation of hepatic steatosis or where the endogenous regenerative capacity of the liver tissue is inhibited.
Ezquer F, Israel Y, Ezquer M, Quintanilla ME, Morales P, Herrera-Marschitz M. Pattent Application Nº 201700237 (27/01/2017). Injectable or intranasal composition comprising unstimulated or preconditioned mesenchymal stem cells (MSC), culture media derived from preconditioned MSC or exosomes derived from their culture and excipients; and its use to reduce drug use or block relapse due to deprivation, in a person with addiction.
Ezquer F, Israel Y, Ezquer M, Quintanilla ME, Morales P, Herrera-Marschitz M,. Pattent Application Nº PCT/CL2018/050063 (3/08/2018). Pharmaceutical composition for the treatment of addiction to psychoactive substances and / or for the prevention of relapses to said addiction
Clinical Studies
Autores: Mizón C, Conget P, Ezquer F, Ezquer M. Administración intravenosa de células madre mesenquimáticas alogénicas contribuyen al tratamiento de pacientes con diabetes mellitus tipo 1. Clínica Alemana de Santiago (2015-2018).
Stem cells for the treatment of patients with type 1 diabetes mellitus |
Development of Novel Therapeutic Alternatives for Alcohol-Use Disorders: A Multidisciplinary Approach |
Acute on chronic liver failure: reversion by systemic administration of 3D spheroids-derived mesenchymal stem cells |
Opioid addiction and associated cognitive damage: Inhibition by intranasal mesenchymal stem cell secretome administration |
MESENCHYMAL STEM CELLS-SECRETOME PROVIDES PROTECTION IN NEONATAL HYPOXIA-REOXYGENATION. MECHANISMS AND TRANSLATIONAL STUDIES |
THE OXIDATIVE STRESS-NEUROINFLAMMATION SYNERGY=> ROLE IN THE PERPETUATION OF ALCOHOL INTAKE AND THERAPEUTIC AVENUES |
INTERNATIONAL RESEARCH NETWORK FOR THE DEVELOPMENT OF INDUCED PLURIPOTENT STEM CELL TECHNOLOGY |
TREATING THE WHOLE NOT THE HOLE=> ADMINISTRATION OF ACELLULAR DERIVATIVE FROM MESENCHYMAL STEM CELLS SUBJECTED TO A PRECONDITIONING STIMULUS REVERTS DIABETIC NEUROPATHY AND PREVENTS DIABETIC FOOT ULCERS |
EVALUATION OF THE THERAPEUTIC EFFECT OF MESENCHYMAL STEM CELL -ACELULAR DERIVATE- ON DRUG INDUCED STEATOSIS, IN A MODEL OF NORMAL AND IMPAIRED LIVER REGENERATION CAPACITY |
DONOR MULTIPOTENT MESENCHYMAL STROMAL CELLS MODIFY THE NATURAL EVOLUTION OF RETINAL DAMAGE IN DIABETIC MICE |
THE ETIOLOGY OF DIABETES AND/OR THE STAGE OF DIABETIC NEPHROPATHY MODIFY THE RENOPROTECTIVE EFFECT OF DONOR MULTIPOTENT MESENCHYMAL STROMAL CELLS? |
IDENTIFICATION OF CELLULAR AND MOLECULAR MECHANISMS BEHIND BETA-PANCREATIC ISLETS REGENERATION INDUCED BY MULTIPOTENT MESENCHYMAL STROMAL CELLS ADMINISTRATION INTO TYPE 1 DIABETIC MICE. |
IDENTIFICACION DE EPITOPES INMUNODOMINANTES INVOLUCRADOS EN LA RESPUESTA INMUNE CELULAR CONTRA HANTAVIRUS ANDES Y CARACTERIZACION DE LOS LINFOCITOS T RESPONSABLES=> BASE PARA EL DESARROLLO DE UNA VACUNA. |

Fernando Ezquer
Full Professor
Center for Regenerative Medicine
Universidad del Desarrollo
Santiago, Chile

Eduardo Ezquer
Director/Full Professor
Centro de Medicina Regenerativa
UNIVERSIDAD DEL DESARROLLO, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS
Santiago, Chile

Paola Morales
Profesor Asociado
Programa Farmacología Molecular & Clínica, ICBM,
Universidad de Chile
Santiago, Chile

J Daniel Carpio
Director Ejecutivo-Profesor Asociado
Unidad Microscopía Electrónica
Universidad Austral de Chile
Valdivia, Chile

María Quintanilla
PROFESOR ASOCIADO
FARMACOLOGÍA MOLECULAR Y CLÍNICA
UNIVERSIDAD DE CHILE, FACULLTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA
Santiago, Chile

Maria Olivares
Docente Investigador
Instituto de Ciencias e Innovación en Medicina
Universidad del Desarrollo
Santiago, Chile

Agustin Martinez
Profesor Titular
Instituto de Neurociencia
UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO
Valparaíso, Chile

Lorena Lobos
Principal Investigator-Associate Proffesor
Facultad of Medicine - Clinic Alemana
Universidad Del Desarrollo
santiago, Chile

Micaela Ricca
Subdirección Área Veterinaria
Área Veterinaria
Fundación Ciencia & Vida
Santiago, Chile

Yedy Israel
Profesor Titular
Farmacologia Molecular y Clinica
UNIVERSIDAD DE CHILE, FACULTAD DE CS QUIMICAS Y FARMACÉUTICAS, LAB. FARMACOTERAPIA GÉNICA
Santiago, Chile

Marcelo Kogan
Academico
Quimica Farmacologica y Toxicologica
UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS
Santiago, Chile

Carolina Oliva
Investigadora y Coordinadora Áreas STEM
Vicerrectoría de Investigación y Doctorados
Universidad Autónoma de Chile
Santiago, Chile

Vania Figueroa
Directora InES Género y CTGénero, Coordinadora de Vinculación de Investigación Aplicada
Centro de Comunicación de las Ciencias
Universidad Autónoma de Chile
Santiago, Chile

Jaime Gutierrez
Associate Professor and Researcher
Tecnología Médica
Universidad San Sebastián
Santiago, Chile

Daniel Cabrera
Investigador Adjunto
Gastroenterología
Pontificia Universidad Catolica de Chile
santiago, Chile

Cristhian Urzúa
Director
Oftalmologia
Laboratorio de Enfermedades Autoinmunes Oculares y Sistémicas. Universidad de Chile
Santiago, Chile

Vinicius Ramos Henriques
Associate Professor
Advanced Center for Chronic Diseases - ACCDiS
Univesidad de Chile
Santiago, Chile

LUIS SOBREVIA
Professor
Division of Obstetrics and Gynaecology
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
SANTIAGO, Chile

Rodrigo Del Rio
Assistant Professor
Physiology
Pontificia Universidad Católica de Chile
Santiago, Chile

Mauricio Retamal
Associate Professor
Programa de Comunicación Celular en Cancer
Universidad del Desarrollo
Santiago, Chile

Maria Paz Marzolo
Profesor Titular
Departamento de Biología Celular y Molecular
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, FAC. CIENCIAS BIOLOGICAS, DEPTO. BIOLOGIA
Santiago, Chile

Maria-Isabel Yuseff
Associate Professor
Cellular and Molecular Biology
Pontificia Universidad Católica de Chile
Santiago, Chile

Valentina Castillo
Investigadora Postdoctoral
Instituto de Ingeniería Biológica y Médica
Pontificia Universidad Católica de Chile
Santiago, Chile

Gonzalo Encina
Investigador
Instituto de Ciencias e Innovación en Medicina
Universidad del Desarrollo
Santiago, Chile