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Marcelo Andrés Muñoz Flores

Profesor Auxiliar

Universidad Austral de Chile

Valdivia, Chile

QuÃmica y actividad biolÃ³gica de los metabolitos aislados Â de plantas y microorganismos; BiotransformaciÃ³n de metabolitos secundarios; QuÃmica Ambiental; Natural Products Chemistry; Stereochemistry; Organic Synthesis; SÃntesis de Eteres y PoliÃ©teres; SÃntesis de SulfÃ³xidos; Modificaciones SintÃ©ticas de Compuestos Naturales; NEUROFISIOLOGIA; NEUROFARMACOLOGIA; BUSQUEDA DE COMPUESTOS NEUROACTIVOS; Quimica de Productos Naturales; Estudios de actividad Neuromoduladora de metabolitos secundarios

Química, UNIVERSIDAD DE CHILE. Chile, 2008
Química, UNIVERSIDAD DE CHILE. Chile, 2003

Profesor Auxiliar Full Time

UNIVERSIDAD AUSTRAL DE CHILE

Ciencias

Valdivia, Chile

2008 - A la fecha

Profesor Auxiliar Full Time

Universidad Austral de Chile

Valdivia, Chile

2003 - A la fecha


A SINGLE COLUMN CHIROPTICAL HPLC BATCH ANALYSIS OF TEN AROMATIC ALCOHOLS María-Paz Orellana; Daniela Poblete Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2019)
CHIRAL CHROMATOGRAPHIC ANALYSIS AND ABSOLUTE STEREOCHEMISTRY OF RACEMIC CHLORPHENERAMINE USING CHIRAL HPLC-CD-OR AND TD-DFT CALCULATIONS Article ISI SCIELO Journal of the Chilean Chemical Society (2018)
ABSOLUTE CONFIGURATION ASSIGNMENT IN RACEMIC trans-STILBENE OXIDE USING CHIRAL LIQUID CHROMATOGRAPHY WITH COMBINED CHIROPTICAL DETECTION AND TIME-DEPENDENT DENSITY FUNCTIONAL THEORY CALCULATIONS JUAN P CASTILLO-GONZÁLEZ; NATALIA I GONZÁLEZ-PEÑA; Marcelo A. Muñoz Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2016)
Enantiomeric high-performance liquid chromatography resolution and absolute configuration of 6 beta-benzoyloxy-3 alpha-tropanol Article ISI SCOPUS JOURNAL OF SEPARATION SCIENCE (2016)
Vibrational Circular Dichroism Absolute Configuration of 9,12-Cyclomulin-13-ol, a Diterpene from Azorella and Laretia Species Munoz, MA; San-Martin, A; Joseph-Nathan, P Article NATURAL PRODUCT COMMUNICATIONS (2015)
Absolute configuration of scopadulane diterpenes from Calceolaria species Chamy, C; Bucio, MA; Hernandez-Barragan, A; Joseph-Nathan, P Article ISI SCOPUS TETRAHEDRON LETTERS (2014)
Chiral Resolution and Absolute Configuration of 3 alpha,6 beta-Dicinnamoyloxytropane and 3 alpha,6 beta-Di(1-ethyl-1H-pyrrol-2-ylcarbonyloxy)tropane, Constituents of Erythroxylum Species Munoz, MA; Arriagada, S; Joseph-Nathan, P Article NATURAL PRODUCT COMMUNICATIONS (2014)
Stereospecific (5)J(Hortho,OMe) couplings in methoxyindoles, methoxycoumarins, and methoxyflavones Alvarez-Cisneros, C; Munoz, MA; Suarez-Castillo, OR; Perez-Hernandez, N; Cerda-Garcia-Rojas, CM; Morales-Rios, MS; Joseph-Nathan, P Article MAGNETIC RESONANCE IN CHEMISTRY (2014)
Chiroptical Studies of Flavanone Bucio, María A. Article NATURAL PRODUCT COMMUNICATIONS (2013)
Absolute Configuration and H-1 NMR Characterization of Rosmaridiphenol Diacetate Muñoz M.A.; Perez-Hernandez, N; Pertino M.W.; Schmeda-Hirschmann, G; Joseph-Nathan, P Article ISI SCOPUS Journal of Natural Products (2012)
Absolute configuration and stereochemical analysis of 3 alpha,6 beta-dibenzoyloxytropane Muñoz M.A.; Martínez M; Joseph-Nathan, P Article ISI SCOPUS Phytochemistry Letters (2012)
ABSOLUTE CONFIGURATION OF THE MERODITERPENOIDS TAONDIOL AND EPITAONDIOL DIACETATES BY VIBRATIONAL CIRCULAR DICHROISM Muñoz M.A.; Areche, C; Rovirosa, J; Gordillo-Roman B.; Joseph-Nathan, P Article ISI SCOPUS Heterocycles (2012)
Determination of absolute configuration of salvic acid, an ent-labdane from Eupatorium salvia, by vibrational circular dichroism Muñoz M.A.; Urzúa, A; Echeverría, J.; Hernandez-Barragan, A; Joseph-Nathan, P Article ISI SCOPUS Phytochemistry (2012)
Inhibitory Activities on Mammalian Central Nervous System Receptors and Computational Studies of Three Sesquiterpene Lactones from Coriaria ruscifolia subsp ruscifolia Pérez, C.; Becerra, J.; Manriquez-Navarro, P; Silva, M; Aguayo, L. G.; Fuentealba, J; Guzmán J.L.; Joseph-Nathan, P; Jimenez, V; Muñoz M.A. Article ISI SCOPUS Chemical and Pharmaceutical Bulletin (2011)
Solid State Structure and Absolute Configuration of Filifolinol Acetate Urzúa, A; Echeverría, J.; Modak,B; Joseph-Nathan, P Article ISI SCOPUS Natural Product Communications (2011)
Stereochemical Analysis of Leubethanol, an Anti-TB-Active Serrulatane, from Leucophyllum frutescens Molina-Salinas, GM; Rivas-Galindo, VM; Said-Fernandez, S; Lankin, DC; Joseph-Nathan, P; Pauli, GF; Waksman N. Article ISI SCOPUS Journal of Natural Products (2011)
Absolute Configuration Determination and Conformational Analysis of (-)-(3S,6S)-3 alpha,6 beta-Diacetoxytropane Using Vibrational Circular Dichroism and DFT Techniques Muñoz, O.; Joseph-Nathan, P Article ISI SCOPUS Chirality (2010)
ABSOLUTE CONFIGURATION OF SARGAOL ACETATE USING DFT CALCULATIONS AND VIBRATIONAL CIRCULAR DICHROISM Areche, C; Rovirosa, J; San Martin, A; Joseph-Nathan, P Article ISI SCOPUS Heterocycles (2010)
DFT-GIAO(1)H NMR chemical shifts prediction for the spectral assignment and conformational analysis of the anticholinergic drugs (-)-scopolamine and (-)-hyoscyamine Munoz, MA; Joseph-Nathan, P Article MAGNETIC RESONANCE IN CHEMISTRY (2010)
Stereostructure Reassignment and Absolute Configuration of Isoepitaondiol, a Meroditerpenoid from Stypopodium flabelliforme Areche, C; San Martin, A; Rovirosa, J; Hernandez-Barragan, A; Bucio, MA; Joseph-Nathan, P Article ISI SCOPUS Journal of Natural Products (2010)
DFT-GIAO H-1 and C-13 NMR prediction of chemical shifts for the configurational assignment of 6 beta-hydroxyhyoscyamine diastereoisomers Munoz, MA; Joseph-Nathan, P Article MAGNETIC RESONANCE IN CHEMISTRY (2009)
Diastereoisomeric Assignment in a Pacifenol Derivative Using Vibrational Circular Dichroism Chamy, C; Carrasco, A.; Rovirosa, J; Martin, AS; Joseph-Nathan, P Article ISI SCOPUS Chirality (2009)
VCD Determination of the Absolute Configuration of Stypotriol Areche, C; San Martin, A; Rovirosa, J; Joseph-Nathan, P Article ISI SCOPUS NATURAL PRODUCT COMMUNICATIONS (2009)
Absolute configuration of natural diastereoisomers of 6 beta-hydroxyhyoscyamine by vibrational circular dichroism Munoz, MA; Munoz, O; Joseph-Nathan, P Article JOURNAL OF NATURAL PRODUCTS (2006)
Simultaneous determination of N-butylscopolamine and oxazepam in pharmaceutical formulations by first-order digital derivative spectrophotometry Toral, MI; Munoz, MA; Orellana, SL Article JOURNAL OF AOAC INTERNATIONAL (2005)


CHRIAL HPLC WITH MULTIPLE CHIROPTICAL DETECTIONS AND QUANTUM CHEMICAL CALCULATIONS. DEVELOPMENT OF A NOVEL AND RELIABLE METHOPDOLOGY FOR THE ON-LINE DETERMINATION OF ABSOLUTE CONFIGURATION IN ENANTIOMERIC MIXTURES FONDECYT (1141071) Proyecto 2014-2017 Inv. Responsable
Stereochemical Analysis and Absolute Configuration of Biologically Interesting Compounds Through Chromatographic, Chiroptical and Computacional Techniques - Análisis Estereoquímico y Configuración Absoluta de Compuestos de Interés Biológico Mediante Técnicas Cromatográficas, Quirópticas y Computacionales Dirección de Investigación - UACh (S-2013-02) Proyecto 2013-2014 Inv. Principal
Strengthening Capacities to Generate and Transfer Nano-technological Materials of High Added Value - Fortalecimiento de Capacidades para Generar y Transferir Materiales Nanotecnológicos de Alto Valor Agregado Fondo de Innovación para la Competitiviadad - Región de Los Ríos (FIC-2012) Proyecto 2012-2012 Investigador(a)
Identification and Purification of Poli-phenols isolated from Native Cypress of Patagonic-Andine Forests and Evaluation of their Potencial Anti-oxidant, Anti-bacterial, Anti-fungic and Neuroprotecting Capacities Centro de Investigación en Ecosistemas de la Patagonia (CIEP-2009) Proyecto 2009-2011 Coinvestigador(a)
PREPARATION AND ABSOLUTE CONFIGURATION DETERMINATION OF CHIRAL TROPANE ALKALOIDS OF PHARMACOLOGICAL INTEREST FONDECYT (11090083) Proyecto 2009-2012 Inv. Responsable
Stereoselective Preparation and Absolute Configuration Determination of Tropane Alkaloids with Potencial Anti-cancer Activity - Preparación Estereoselectiva y Determinación de la Configuración Absoluta de Alcaloides del Tropano con Potencial Actividad Anti-cancerígena Dirección de Investigación - UACh (DID S-2009-14) Proyecto 2009-2011 Inv. Principal