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Carlos Areche Medina

ASSOCIATE PROFESSOR

UNIVERSIDAD DE CHILE

Santiago, Chile

PRODUCTOS NATURALES; Fungal secondary metabolism; Biotechnology of Natural Products y sus aplicaciones biologicas; Biotransformaciones; Natural Product Chemistry; Pharmacological activity; Medicinal Chemistry; protein NMR.

Natural Product Chemistry, UNIVERSIDAD DE TALCA. Chile, 2007
Organic chemistry, universidad Nacional de Ingenieria. Peru, 2003
Quimico Farmaceutico, UIGV. Chile, 1999

PROFESOR ASOCIADO Full Time

UNIVERSIDAD DE CHILE

CIENCIAS

Santiago, Chile

2009 - A la fecha

pharmacist Full Time

Public Heath Institute

Lima, Peru

1999 - 2003

UNDERGRADUATE STUDENTS

1.- Diego Alonso Vilches Retamal. Purificación de Meroditerpenoides policíclicos del alga parda Stypopodium Flabelliforme. Grado académico de Licenciado en Química. Universidad de Chile. 2009.

2.- Teresa Parra. Síntesis y actividad biológica de diterpenos de Baccharis tola. Grado académico de Químico industrial. UTEM. 2012.

3.- Solange Nuñez. Sintésis del flavonoide pinocembrina. Grado académico de Licenciado en Química. Universidad de Chile. 2012.

4.- Camila Barahona. Sintésis de flavanonas. Grado académico de Licenciado en Química. Universidad de Chile. 2012.

5.- Pamela Labbe. Biotransformacion del meroditerpeno acetato de stypotriol. Químico Industrial UTEM 2013.

6.- Francisco Salgado. Biotransformacion del diterpeno ácido mulin-11,13-dien-20-oico mediante hongos filamentosos. Grado académico de Licenciado en Química. Universidad de Chile. 2013.

7.- Felipe Valdevenito. Estudio Químico de Beilschmiedia miersii “belloto” en curso. Grado académico de Licenciado en Química. Universidad de Chile.

8.- Sebastian Cifuentes. Pruebas de eficiencia de nuevos antioxidantes mediante dpph: extraidos a partir de vegetales endémicos. En curso. Químico Industrial UTEM.

POSTGRADUATE STUDENTS

Qco. Carlos Lima. Estudiante de Doctorado en Ciencias Químicas. UNIDAD EN CURSO

Qco. Francisco Salgado. Estudiante de Maestria en Ciencias Químicas. EN CURSO

ESTANCIA POSTDOCTORAL

CSIC, IPNA

España, 2010

ESTANCIA POSTDOCTORAL EN EL LAB. DE PRODUCTOS MARINOS DEL PROFESOR JOSE DARIAS. IPNA, CSIC, TENERIFE, ESPAÑA.
COIMBRA FELLOWSHIP

IRB, BARCELONA, ESPAÑA

Chile, 2012

ESTANCIA POSTDOCTORAL EN EL LABORATORIO DE RESONANCIA MAGNETICA NUCLEAR DE PROTEINAS BAJO LA DIRECCION DEL PROFESOR MARIA JOSE MACIAS, IRB, BARCELONA, ESPAÑA.


A sustainable application for the extraction of lichen metabolites from Usnea cornuta: nontargeted metabolomics and antioxidant activity Sepúlveda Beatriz; Vargas, Reinaldo; Areche, Carlos Article ISI NATURAL PRODUCT RESEARCH (2023)
Antioxidant activity and enzymatic of lichen substances: A study based on cyclic voltammetry and theoretical Osorio, Edison; Tiznado, William; Ruiz, Lina; Nagles, Orlando; Castaneta, Grover; Areche, Carlos Article ISI CHEMICO-BIOLOGICAL INTERACTIONS (2023)
Phenolic Profile, Antioxidant and Enzyme Inhibition Properties of the Chilean Endemic Plant Ovidia pillopillo (Gay) Meissner (Thymelaeaceae) Gonzalez-Cabrera, Diego A.; Pertino, Mariano Walter; Areche, Carlos; Sepúlveda Beatriz; Borquez, Jorge Article ISI METABOLITES (2022)
Activity of Semi-Synthetic Mulinanes against MDR, Pre-XDR, and XDR Strains of Mycobacterium tuberculosis Martinez-Gonzalez, Maria Alejandrina; Uc-Cachon, Andres Humberto; Borquez, Jorge; Barrios-Garcia, Hugo Brigido; Loyola, Luis Alberto; Areche, Carlos; Dzul-Beh, Angel de Jesus; Barrios-Payan, Jorge Alberto; Escalante-Erosa, Fabiola; Molina-Salinas, Gloria Maria Article ISI METABOLITES (2021)
Coumarin-Chalcone Hybrids as Inhibitors of MAO-B: Biological Activity and In Silico Studies Areche, Carlos Article ISI MOLECULES (2021)
Dammarane triterpenes targeting alpha-synuclein: biological activity and evaluation of binding sites by molecular docking Cornejo, Alberto; Caballero, Julio; simirgiotis, mario; Areche, Carlos; Alfaro, Sergio; Caballero, Leonardo Article ISI JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
Green ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent? Sepúlveda Beatriz; Benites, Derin; Albornoz, Laura; simirgiotis, mario; Castro, Olivio; Areche, Carlos Article ISI NATURAL PRODUCT RESEARCH (2021)
In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease Areche, Carlos; Tiznado, William; Gonzalez-Nilo, Fernando Article ISI FRONTIERS IN CHEMISTRY (2021)
Structure-antioxidant activity relationships in boldine and glaucine: a DFT study Osorio, Edison; Areche, Carlos; Ruiz, Lina M.; Cassels, Bruce K.; Tiznado, William Article ISI NEW JOURNAL OF CHEMISTRY (2021)
Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease Areche, Carlos; Sandoval-Aldana, Angelica; Gonzalez-Nilo, Fernando; Matos, Maria Joao; Osorio, Edison; Tiznado, William Article ISI BIOMEDICINE & PHARMACOTHERAPY (2021)
Are Ionic Liquids Better Extracting Agents Than Toxic Volatile Organic Solvents? A Combination of Ionic Liquids, Microwave and LC/MS/MS, Applied to the Lichen Stereocaulon glareosum Areche, Carlos; Sepúlveda Beatriz Article FRONTIERS IN CHEMISTRY (2020)
Corryocactus brevistylus (K. Schum. ex Vaupel) Britton Rose (Cactaceae): Antioxidant, Gastroprotective Effects, and Metabolomic Profiling by Ultrahigh-Pressure Liquid Chromatography and Electrospray High Resolution Orbitrap Tandem Mass Spectrometry Areche, Carlos; simirgiotis, mario; Borquez, Jorge; Sepúlveda Beatriz Article ISI FRONTIERS IN PHARMACOLOGY (2020)
Isolation, Gastroprotective Effects and Untargeted Metabolomics Analysis of Lycium Minutifolium J. Remy (Solanaceae) Pertino, Mariano Walter; simirgiotis, mario; Borquez, Jorge; Cornejo, Alberto; Areche, Carlos; Sepúlveda Beatriz Article FOODS (2020)
The crystal structure of 1-carboxy-2-(1H-indol-3-yl)-N,N,N-trimethylethan-1-ammonium chloride, C14H19N2O2Cl Areche, Carlos; Moris, Silvana Article ISI ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES (2020)
Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction. Areche, Carlos; Zapata, Francisca; González, Mathias; Díaz, Esteban; Montecinos, Rubén; Hernández, Marcos; Melo, Francisco; Cornejo, Alberto Article ChemistryOpen (2019)
Biological activity and chemical characterization of Pouteria lucuma seeds=> A possible use of an agricultural waste. Guerrero-Castillo, Pedro; Reyes, Sarita; Robles, Juana; Simirgiotis, Mario J; Sepulveda, Beatriz; Fernandez-Burgos, Ronald; Areche, Carlos Article Waste management (New York, N.Y.) (2019)
Mulinane and Azorellane Diterpenoid Biomarkers by GC-MS from a Representative Apiaceae (Umbelliferae) Species of the Andes. Simoneit, Bernd R T; Oros, Daniel R; Jaffé, Rudolf; Didyk-Peña, Alexandra; Areche, Carlos; Sepúlveda, Beatriz; Didyk, Borys M Article Molecules (Basel, Switzerland) (2019)
Mulinum crassifolium Phil; Two New Mulinanes, Gastroprotective Activity and Metabolomic Analysis by UHPLC-Orbitrap Mass Spectrometry De Terrones T.C. Article ISI SCOPUS MOLECULES (2019)
Phytochemical Profiling of (Cactaceae) Growing in Greenhouse Conditions Using Ultra-High-Performance Liquid Chromatographyâ�»Tandem Mass Spectrometry. Cabañas-García, Emmanuel; Areche, Carlos; Jáuregui-Rincón, Juan; Cruz-Sosa, Francisco; Pérez-Molphe Balch, Eugenio Article Molecules (Basel, Switzerland) (2019)
Characterization and Salt Response in Recurrent Halotolerant Exiguobacterium sp SH31 Isolated From Sediments of Salar de Huasco, Chilean Altiplano Fortt, J; Fuentes, B.; Aguayo, D Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)
Continental and Antarctic Lichens=> isolation, identification and molecular modeling of the depside tenuiorin from the Antarctic lichen Umbilicaria antarctica as tau protein inhibitor. Salgado, Francisco; Caballero, Julio; Vargas, Reinaldo; Cornejo, Alberto; Areche, Carlos Article Natural product research (2018)
Gastroprotective Activity of Parastrephia quadrangularis (Meyen), Cabrera from the Atacama Desert Ardiles, Alejandro; Barrientos, Ruth; Simirgiotis, Mario J; Borquez, Jorge; Sepúlveda Beatriz; Areche, Carlos Article ISI SCOPUS MOLECULES (2018)
Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS Salgado, F; Albornoz, L.; Cortez, C; Stashenko, E; Urrea-Vallejo, K; Galicia-Virviescas, C; Ardiles, A; Areche, C Article ISI SCOPUS MOLECULES (2018)
UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC. - Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties Jimenez-Gonzalez, A; Quispe, C; Riveros F.; Simirgiotis, MJ Article ISI SCOPUS JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)
Metabolomic Analysis of the Lichen Everniopsis trulla Using Ultra High Performance Liquid Chromatography-Quadrupole-Orbitrap Mass Spectrometry (UHPLC-Q-OT-MS) Castro, Olivio N.; Santiago, Julio C. Article ISI SCOPUS CHROMATOGRAPHIA (2017)
Metabolomic Analysis of Two Parmotrema Lichens=> P-robustum (Degel.) Hale and P-andinum (Mull. Arg.) Hale Using UHPLC-ESI-OT-MS-MS Torres-Benitez, A; Rivera-Montalvo, M; Sepulveda, B; Castro, ON; Nagles, E; Simirgiotis, MJ; Garcia-Beltran, O; Areche, C Article MOLECULES (2017)
Metabolomic Analysis of Two Parmotrema Lichens=> P-robustum (Degel.) Hale and P-andinum (Mull. Arg.) Hale Using UHPLC-ESI-OT-MS-MS Torres-Benitez, A; Rivera-Montalvo, M; Sepulveda, B; Castro, ON; Nagles, E; Simirgiotis, MJ; Garcia-Beltran, O; Areche, C Article MOLECULES (2017)
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to beta sheet in tau protein linked to Alzheimer's disease Article ISI SCOPUS JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
UHPLC high resolution orbitrap metabolomic fingerprinting of the unique species Ophryosporus triangularis Meyen from the Atacama Desert, Northern Chile Mocan, Andrei; Villatoro, José Miguel; Echiburu-Chau, Carlos Article ISI SCOPUS Revista d’educació superior en Farmàcia. Edusfarm. (2017)
Fast Detection of Phenolic Compounds in Extracts of Easter Pears (Pyrus communis) from the Atacama Desert by Ultrahigh-Performance Liquid Chromatography and Mass Spectrometry (UHPLC-Q/Orbitrap/MS/MS) Simirgiotis, MJ; Quispe, C; Bórquez J.; Areche, C; Sepúlveda B. Article ISI SCOPUS MOLECULES (2016)
Gastroprotective activity of synthetic coumarins: Role of endogenous prostaglandins, nitric oxide, non-protein sulfhydryls and vanilloid receptors Torres-Benítez, Alfredo; Reyes-Ortíz, Johanna Article ISI SCOPUS BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2016)
Gastroprotective effects of new diterpenoid derivatives from Azorella cuatrecasasii Mathias & Constance obtained using a beta-cyclodextrin complex with microbial and chemical transformations Article ISI SCOPUS BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2016)
Phenolic Compounds in Chilean Mistletoe (Quintral, Tristerix tetrandus) Analyzed by UHPLC-Q/Orbitrap/MS/MS and Its Antioxidant Properties simirgiotis, m. j.; Quispe, C; Areche, C; Sepúlveda B. Article ISI SCOPUS MOLECULES (2016)
Secondary Metabolites in Ramalina terebrata Detected by UHPLC/ESI/MS/MS and Identification of Parietin as Tau Protein Inhibitor Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
3-Nitroasterric Acid Derivatives from an Antarctic Sponge-Derived Pseudogymnoascus sp Fungus Figueroa L.; Jiménez C; Rodriguez J.; Areche, C; Chavez, R; Henriquez, M.; de la Cruz, M; Díaz, C.; Segade, Y; Vaca I. Article ISI SCOPUS Journal of Natural Products (2015)
Antioxidant Capacities and Analysis of Phenolic Compounds in Three Endemic Nolana Species by HPLC-PDA-ESI-MS Simirgiotis, MJ; Benites, J.; Areche, C; Sepúlveda B. Article ISI SCOPUS MOLECULES (2015)
Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls Parra, T; Benites, J.; Sepúlveda B.; Simirgiotis, M.; Areche, C Article ISI SCOPUS Bioorganic and Medicinal Chemistry Letters (2015)
Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its Gastroprotective Effect in Mouse Model Areche, C; Benites, J.; Cornejo A.; Garcia-Beltran, O; Simirgiotis, MJ; Sepúlveda B. Article ISI SCOPUS MARINE DRUGS (2015)
A new mulinane diterpenoid from the cushion shrub Azorella compacta growing in Peru Salgado, F; Areche, C; Sepúlveda B.; Simirgiotis, MJ; Cáceres F.; Quispe, C; Quispe, L; Cano, T Article ISI SCOPUS PHARMACOGNOSY MAGAZINE (2014)
An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers Areche, Carlos; Sepúlveda Beatriz; Martin, Aurelio San; Garcia-Beltrán, Olimpo; simirgiotis, mario; Cañete, Alvaro Article ISI SCOPUS ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Anthocyanin Characterization, Total Phenolic Quantification and Antioxidant Features of Some Chilean Edible Berry Extracts Brito, Angel; Areche, Carlos; Sepúlveda Beatriz; Kennelly, Eduard; simirgiotis, mario Article ISI SCOPUS MOLECULES (2014)
Concise and Straightforward Asymmetric Synthesis of a Cyclic Natural Hydroxy-Amino Acid simirgiotis, m. j.; Vallejos J.; Areche, C; Sepúlveda B. Article ISI SCOPUS MOLECULES (2014)
Coumarins isolated from Esenbeckia alata (Rutaceae) Garcia-Beltran, O; Areche, C; Cassels, B.K.; Cuca Suarez L.E. Article ISI SCOPUS BIOCHEMICAL SYSTEMATICS AND ECOLOGY (2014)
HPLC-PDA-MS Profiles of Phenolic Compounds and Antioxidant Activity of Fruits From Three Citrus Species Consumed in Northern Chile. Brito, Angel; Areche, Carlos; Sepúlveda Beatriz; simirgiotis, mario Article MOLECULES (2014)
HPLC-UV-MS Profiles of Phenolic Compounds and Antioxidant Activity of Fruits from Three Citrus Species Consumed in Northern Chile Brito A.; Areche, C; Sepúlveda B.; Simirgiotis, MJ Article ISI SCOPUS MOLECULES (2014)
Further mulinane diterpenoids from Azorella compacta Areche, C; Rojas-Alvarez, F; Campos-Briones, C; Lima, C; Sepúlveda B. Article ISI SCOPUS Journal of Pharmacy and Pharmacology (2013)
LICHENS: MIGHT BE CONSIDERED AS A SOURCE OF GASTROPROTECTIVE MOLECULES? Sepúlveda Beatriz; CHAMY, MARIA CRISTINA; PIOVANO, MARISA; Areche, Carlos Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2013)
Variations in the chemical profile and biological activities of licorice (Glycyrrhiza glabra L.), as influenced by harvest times Cheel J.; Tumova, L; Areche, C; Van Antwerpen, P; Neve, J; Zouaoui-Boudjeltia, K; Martin, AS; Vokral, I; Wsol, V; Neugebauerova, J Article ISI SCOPUS Acta Physiologiae Plantarum (2013)
Why is quercetin a better antioxidant than taxifolin? Theoretical study of mechanisms involving activated forms Osorio, E; Areche, C; Florez E.; Tiznado, W Article ISI SCOPUS JOURNAL OF MOLECULAR MODELING (2013)
ABSOLUTE CONFIGURATION OF THE MERODITERPENOIDS TAONDIOL AND EPITAONDIOL DIACETATES BY VIBRATIONAL CIRCULAR DICHROISM Muñoz M.A.; Areche, C; Rovirosa, J; Gordillo-Roman B.; Joseph-Nathan, P Article ISI SCOPUS Heterocycles (2012)
Biological Activity of Isoflavonoids from Azorella madreporica Quesada, L; Areche, C; Astudillo, L; Gutiérrez M; Sepúlveda B.; San Martin, A Article ISI SCOPUS Natural Product Communications (2012)
STRUCTURAL REASSIGNMENT OF EPIERYTHRATIDINE, AN ALKALOID FROM Erythrina fusca, BASED ON NMR STUDIES AND COMPUTATIONAL METHODS Garcia-Beltran, O; Soto-Delgado, J; Iturriaga-Vasquez, P; Areche, C; Cassels, B.K. Article ISI SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2012)
STRUCTURAL REASSIGNMENT OF EPIERYTHRATIDINE, AN ALKALOID FROM Erythrinafusca, BASED ON NMR STUDIES AND COMPUTATIONAL METHODS Garcia-Beltrán, Olimpo; SOTO-DELGADO, JORGE; Iturriaga-Vásquez, Patricio; Areche, Carlos; Cassels, Bruce K. Article Journal of the Chilean Chemical Society (2012)
Anti-Proliferative Activity of Meroditerpenoids Isolated from the Brown Alga Stypopodium flabelliforme against Several Cancer Cell Lines Pereira, DM; Cheel J.; Areche, C; San Martin, A; Rovirosa, J; Silva, LR; Valentao P.; Andrade, PB Article ISI SCOPUS MARINE DRUGS (2011)
Biotransformation of Stypotriol triacetate by Aspergillus niger Areche, C; Vaca I.; Labbé P.; Soto-Delgado, J; Astudillo, L; Silva, M; Rovirosa, J; San Martin, A Article ISI SCOPUS Journal of Molecular Structure (2011)
Gastroprotective Activity of Epitaondiol and Sargaol Areche, C; San Martin, A; Rovirosa, J; Sepúlveda B. Article ISI SCOPUS Natural Product Communications (2011)
ABSOLUTE CONFIGURATION OF SARGAOL ACETATE USING DFT CALCULATIONS AND VIBRATIONAL CIRCULAR DICHROISM Areche, C; Rovirosa, J; San Martin, A; Joseph-Nathan, P Article ISI SCOPUS Heterocycles (2010)
Diterpenoids from Azorella madreporica and Their Antibacterial Activity Areche, C; Vaca I.; Bórquez J.; Rovirosa, J; San Martin, A Article ISI SCOPUS PLANTA MEDICA (2010)
Stereostructure Reassignment and Absolute Configuration of Isoepitaondiol, a Meroditerpenoid from Stypopodium flabelliforme Areche, C; San Martin, A; Rovirosa, J; Hernandez-Barragan, A; Bucio, MA; Joseph-Nathan, P Article ISI SCOPUS Journal of Natural Products (2010)
An unusual halogenated meroditerpenoid from Stypopodium flabelliforme: Studies by NMR spectroscopic and computational methods Areche, C; San Martin, A; Rovirosa, J; Soto-Delgado, J; Contreras R. Article ISI SCOPUS PHYTOCHEMISTRY (2009)
Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean Lamiaceae Sphacele chamaedryoides (Balbis) Briq. Areche, C; Schmeda-Hirschmann, G; Theoduloz, C; Rodriguez JA. Article ISI SCOPUS JOURNAL OF PHARMACY AND PHARMACOLOGY (2009)
TRITERPENOIDS FROM Azorella trifurcata (Gaertn.) Pers AND THEIR EFFECT AGAINST THE ENZYME ACETYLCHOLINESTERASE Areche, C; Cejas, P; Thomas P.; San Martin, A; Astudillo, L; Gutiérrez M Article ISI SCOPUS QUIMICA NOVA (2009)
VCD Determination of the Absolute Configuration of Stypotriol Areche, C; San Martin, A; Rovirosa, J; Joseph-Nathan, P Article ISI SCOPUS NATURAL PRODUCT COMMUNICATIONS (2009)
Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells de Jesus, MB; Zambuzzi, WF; de Sousa, RRR; Areche, C; de Souza, ACS; Aoyama, H; Schmeda-Hirschmann, G; Rodriguez JA.; Brito, ARMD; Peppelenbosch, MP; et al. Article ISI SCOPUS BIOCHIMIE (2008)
Gastroprotective activity of ferruginol in mice and rats: effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls Areche, C; Theoduloz, C; Yanez, T; Souza-Brito, ARM; Barbastefano, V; de Paula, D; Ferreira, AL; Schmeda-Hirschmann, G; Rodriguez JA. Article ISI SCOPUS JOURNAL OF PHARMACY AND PHARMACOLOGY (2008)
Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus Areche, C; Bórquez J.; Rovirosa, J; San Martin, A Article ISI SCOPUS MAGNETIC RESONANCE IN CHEMISTRY (2008)
Gastroprotective and cytotoxic effect of semisynthetic ferruginol derivatives Areche, C; Rodriguez JA.; Razmilic I.; Yanez, T; Theoduloz, C; Schmeda-Hirschmann, G Article ISI SCOPUS JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)


Depsides, despsidones and anthraquinones from Chilean lichens=> Isolation, molecular simulation and biological activity as tau-reducing agents. FONDECYT (1150745) Proyecto 2015-2018 Inv. Principal
Polyphenols isolated from antarctic Lichens as inhibitors of tau aggregation INACH (RT 13-13) Proyecto 2013-2016 Inv. Principal
Terrestrial and marine organism as source of gastroprotective drugs FONDECYT (11110241) Proyecto 2011-2014 Inv. Responsable
azorella compacta como fuente de metabolitos activos VID (Universidad de Chile) (VID I-09/18-2) Proyecto 2009-2011 Inv. Principal
Natural or Hemisynthetic products of Pharmacological agrochemical and forestry interest and its possible biotechnological development PIA (ACT-38) Proyecto 2006-2009 Investigador(a)

José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

Mario Silva

Emeritus Professor

Botany Department

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

margarita gutierrez

Proffesor

UNIVERSIDAD DE TALCA

Talca, Chile

Renato Chavez

Full Professor

Biology

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Inmaculada Vaca

Associate Professor

Chemistry Department

UNIVERSIDAD DE CHILE

Santiago, Chile

AURELIO SAN MARTIN

Profesor Asociado (media jornada)

de Ciencias y Recursos Naturales

FACULTAD DE CIENCIAS

Punta Arenas, Chile

Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Lina Ruiz

Academico Docente Investigador

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Bruce Cassels

Profesor Titular

Departamento de Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE QUÍMICA

Santiago, Chile

Carlos Areche

ASSOCIATE PROFESSOR

CHEMISTRY

UNIVERSIDAD DE CHILE

Santiago, Chile

Bárbara Fuentes

Acádemcia, Investigadora, Jefe de Carrera

Departamento de Ingeniería Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

FRANCISCO REMONSELLEZ

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

EDWIN PÉREZ

Profesor Asociado

Departamento de Química Orgánica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Alvaro Cañete

Profesor-investigador

instituto de ciencias químicas aplicadas

Universidad Autónoma de Chile

Santiago, Chile

Juana Rovirosa

Professor Ad. Honorem

Ciencias

Facultad de Ciencias y Recursos Naturales

Punta Arenas, Chile

Marcelo Muñoz

Profesor Auxiliar

Instituto de Ciencias Químicas

Universidad Austral de Chile

Valdivia, Chile

Javier Echeverría

Profesor Asistente e Investigador

Departamento de Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

Luisa Quesada

Docente e investigadora

Nutrición y Dietética

Universidad San Sebastián

Valdivia, Chile

Jorge Soto

Profesor Asistente

Departamento de Ciencias Quimicas

Universidad Andrés Bello

Viña del Mar, Chile

Edison Osorio

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

William Tiznado

Full professor

Chemical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Manuel Osorio

Docente

Medicina

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

Daniel Aguayo

Associate Professor

ITISB

UNIVERSIDAD ANDRES BELLO

Viña del Mar, Chile

Reinaldo Vargas

Académico

Departamento de Biología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

Julio Caballero

Full Professor

Departamento de Bioinformática

Universidad de Talca

Talca, Chile

Renato Contreras

professor

Quimica

Universidad de Chile

Santiago, Chile

Francisco Melo

FULL PROFESSOR

FISICA

UNIVERSIDAD DE SANTIAGO DE CHILE

SANTIAGO, Chile

Felipe Aguilar

Académico

UNIVERSIDAD DE AYSEN

Coyhaique, Chile

Javier Romero

Profesor Asistente

Departamento de Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Beatriz Sepúlveda

Profesor adjunto

UNIVERSIDAD ANDRES BELLO

Jessica Bravo

Profesor asociado, investigador jornada

UNIVERSIDAD DIEGO PORTALES

santiago, Chile

CLAUDIO PARRA

Profesor Asistente

Química Orgánica

Universidad de Concepción

Concepción, Chile

Alejandro Vásquez

Profesor Asistente

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

silvana moris

Investigadora

vicerrectoria de investigacion y postgrado

Universidad Católica del Maule

Talca, Chile

MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Cristina Quispe

ACADEMICO

FACULTAD DE CIENCIAS DE LA SALUD

UNIVERSIDAD ARTURO PRAT

IQUIQUE, Chile

osvaldo yañez

Académico Investigador

Facultad de Ingeniería y Negocios

Universidad de Las Américas

Santiago, Chile

Jorge Borquez

Académico

Química

Universidad de Antofagasta

Antofagasta, Chile

Coral Pardo

Investigador postdoctoral

Universidad Católica del Norte

antofagasta, Chile

Juan Castro

Post-Doctorante

Universidad Católica del Norte

Antofagasta, Chile

Sergio Barahona

Pablo Aguilar

Academico

Departamento de Biotecnologia

Universidad de Antofagasta

Antofagasta, Chile

Rogelio Hernández

Jefe de la unidad Patología Experimental

DEPARTAMENTO DE PATOLOGÍA

INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICICIÓN SALVADOR ZUBIRAN

Ciudad México, México

Marlene Henríquez

Gestora de Transferencia Tecnológica

Dirección de Gestión Tecnológica

Universidad de Santiago de Chile

Santiago, Santiago Metropolitan, Chile, Chile

Ruth Barrientos

Docente

Química y Farmacia

Universidad San Sebastián

Puerto Montt, Chile

Carlos Areche Medina

Líneas de Investigación

Educación

Natural Product Chemistry, UNIVERSIDAD DE TALCA. Chile, 2007

Organic chemistry, universidad Nacional de Ingenieria. Peru, 2003

Quimico Farmaceutico, UIGV. Chile, 1999

Experiencia Académica

PROFESOR ASOCIADO Full Time

Experiencia Profesional

pharmacist Full Time

Formación de Capital Humano

Premios y Distinciones

ESTANCIA POSTDOCTORAL

COIMBRA FELLOWSHIP

Article (67)

Proyecto (5)

Depsides, despsidones and anthraquinones from Chilean lichens=> Isolation, molecular simulation and biological activity as tau-reducing agents.

Polyphenols isolated from antarctic Lichens as inhibitors of tau aggregation

Terrestrial and marine organism as source of gastroprotective drugs

azorella compacta como fuente de metabolitos activos

Natural or Hemisynthetic products of Pharmacological agrochemical and forestry interest and its possible biotechnological development