PDI - Resultado de Búsqueda

Alberto Jesús Cornejo Mora

ICC

Santiago, Chile


Internalization of external tau aggregates co-localize with early endocytic markers and lysosomes Melo, F; Flores, N; Navarrete, I; Caballero, L; Cornejo, A Article ISI SCOPUS Biophysical Chemistry (2025)
Rosmarinic acid turned α-syn oligomers into non-toxic species preserving microtubules in Raw 264.7 cells Flores, N; Rivillas-Acevedo, L; Caballero, J; Melo, F; Caballero, L; Areche, C; Fuentealba, D; Aguilar, F.; Cornejo, A Article ISI SCOPUS Bioorganic Chemistry (2024)
α-Synuclein Drives Tau's Cytotoxic Aggregates Formation through Hydrophobic Interactions Ojeda, Ana; Cofré, Valentina; Melo, Francisco; CABALLERO-AVIAL, LEONARDO ANTONIO; FUENTEALBA-PATINO, DENIS; Cornejo, Alberto Article ISI SCOPUS ChemPlusChem (2023)
Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera Sepulveda, Beatriz; Cornejo, Alberto; Barcenas-Perez, Daniela; Cheel, Jose; Areche, Carlos Article ISI Healthcare (2022)
Dammarane triterpenes targeting alpha-synuclein: biological activity and evaluation of binding sites by molecular docking Cornejo, Alberto; Caballero, Julio; Simirgiotis, Mario; Areche, Carlos; Alfaro, Sergio; Caballero, Leonardo Article ISI JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
The Cytotoxic Effect of alpha-Synuclein Aggregates Caballero, Leonardo; Zamorano, Esteban; Ventura, Natalia; Navarro, Camilo; Doll, Irving; Zamorano, Pedro; Cornejo, Alberto Article ISI CHEMPHYSCHEM (2021)
Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine‐Cysteine Interaction Areche, Carlos; Zapata, Francisca; González, Mathias; Díaz, Esteban; Montecinos, Rubén; Hernández, Marcos; Melo, Francisco and Cornejo Article CHEMISTRYOPEN (2019)
Continental and Antarctic Lichens=> isolation, identification and molecular modeling of the depside tenuiorin from the Antarctic lichen Umbilicaria antarctica as tau protein inhibitor. Salgado, Francisco; Caballero, Julio; Vargas, Reinaldo; Cornejo, Alberto; Areche, Carlos Article Natural product research (2018)
Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS Francisco Salgado, Laura Albornoz; Carmen Cortéz, Elena Stashenko; Kelly Urrea-Vallejo, Edgar Nagles; Cesar Galicia-Virviescas, Alberto Cornejo; Alejandro Ardiles, Mario Simirgiotis; Olimpo García-Beltrán, and Carlos Areche. Article MOLECULES (2018)
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer's disease. Alberto Cornejo, Felipe Aguilar Sandoval; Leonardo Caballero, Luis Machuca; Patricio Muñoz, Julio Caballero; George Perry, Alejandro Ardiles; Carlos Areche, and Francisco Melo. Article J Enzyme Inhib Med Chem (2017)
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to b sheet in tau protein linked to Alzheimer’s disease Cornejo, Alberto; Aguilar Sandoval, Felipe; Caballero, Leonardo; Machuca, Luis; Muñoz, Patricio; Caballero, Julio; Perry, George=> Ardiles; Alejandro, Areche; Carlos and Melo, Francisco. Article JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons Sook Wern Chua, Alberto Cornejo; Janet van Eersel, Claire H. Stevens; Inmaculada Vaca, Mercedes Cueto; Michael Kassiou , Amadeus Gladbach; Alex Macmillan, Lev Lewis ; Renee Whan, and Lars M. Ittner Article ACS Chemical Neuroscience (2017)
Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its Gastroprotective Effect in Mouse Model Areche, C; Benites, J; Cornejo, A; García-Beltran, O; Simirgiotis, MJ; Sepúlveda, B Article ISI SCOPUS Marine Drugs (2015)
Fulvic Acid Inhibits Aggregation and Promotes Disassembly of Tau Fibrils Associated with Alzheimer's Disease Cornejo, A; Jimenez, JM; Caballero, L; Melo, F; Maccioni, RB Article ISI SCOPUS Journal of Alzheimer's Disease (2011)
Mechanisms of Tau Self-Aggregation and Neurotoxicity G. Farías*, A. Cornejo; J. Jiménez, L. Guzmán and R.B. Maccioni Article Current Alzheimer Research (2011)
Calcineurin B of the human protozoan parasite Trypanosoma cruzi is involved in cell invasion Cornejo, A; Orrego, PR; Cordero, EM; Cortez, M; Olivares, H; Neira, I; Sagua, H; da Silveira, JF; Yoshida, N; Gonzalez, J Article ISI SCOPUS MICROBES AND INFECTION (2008)
A novel protein phosphatase 2A (MA) is involved in the transformation of human protozoan parasite Trypanosoma cruzi Gonzalez, J; Cornejo, A; Santos, MRM; Cordero, EM; Gutierrez, B; Porcile P.; Mortara, RA; Sagua, H; da Silveira, JF Article ISI SCOPUS BIOCHEMICAL JOURNAL (2003)


Might paretin have effect against tau protein? Cornejo, A; Areche, C; Perez, E; Sepúlveda, B; Maccioni, RB Abstract ISI PLANTA MEDICA (2012)


DEPSIDES, DEPSIDONES AND ANTHRAQUINONES FROM CHILEAN LICHENS=> ISOLATION, MOLECULAR SIMULATION AND BIOLOGICAL ACTIVITY AS TAU-REDUCING AGENTS FONDECYT (1150745) Proyecto 2015-2019 Coinvestigador(a)
Polifenoles aislados de liquenes de la antartica con actividad inhibitoria de la agregación de la proteina tau Título INACH (RT1313) Proyecto 2014-2016 Coinvestigador(a)
Polyphenolic molecules attenuate tau pathology in a transgenic mice model FellowShip Becas Chile (N° 74140034) Proyecto 2013-2014 Inv. Principal
CELLULAR AND MOLECULAR ASPECTS OF NEUROIMMUNOMODULATION IN THE ALZHEIMER S TYPE NEURONAL DEGENERATION FONDECYT (1110373) Proyecto 2011-2015 Personal técnico y/o de apoyo
IN THE SEARCH OF TAU BINDING MOLECULES WITH BIOMEDICAL RELEVENCE FOR ALZHEIMER S DISEASE=> STRUCTURAL AND FUNCIONAL STUDIES ON THE INTERACTIONS OF TAU WITH BENZIMIDAZOLES. FONDECYT (1080254) Proyecto 2008-2011 Tesista

2

Ricardo Maccioni

DIRECTOR

RESEARCH AND DEVELOPMENT

CENTRO INTERNACIONAL DE BIOMEDICINA (ICC)

SANTIAGO, Chile

11

Alberto Cornejo

ICC

Santiago, Chile

4

Carlos Areche

ASSOCIATE PROFESSOR

CHEMISTRY

UNIVERSIDAD DE CHILE

Santiago, Chile

1

PEDRO ZAMORANO

Profesor Asociado

Depto Biomédico

Universidad de Antofagasta

Antofagasta, Chile

1

Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1

Julio Caballero

Full Professor

Departamento de Bioinformática

Universidad de Talca

Talca, Chile

5

Francisco Melo

FULL PROFESSOR

FISICA

UNIVERSIDAD DE SANTIAGO DE CHILE

SANTIAGO, Chile

2

MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2

Jorge Araya

Profesor Asociado

Departamento de Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

2

Esteban Cordero

Assistant Professor

Universidad Mayor

Santiago, Chile

1

José Jiménez

Postdoc

Investigación

Fundacion Ciencia y Vida

Santiago, Chile

1

Bessy Gutiérrez

PROFESORA

TECNOLOGÍA MÉDICA

Universidad de Antofagasta

Antofagasta, Chile

1

IVAN NEIRA

Académico

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile