Man

Inmaculada Vaca Cerezo

Associate Professor

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Natural Product Chemistry; Microbiology Chemistry, Fungal secondary metabolism; Biotechnology; Molecular genetic of filamentous fungi

Educación

  •  Chemist, Universidad de Valladolid. España, 2000
  •  Biotechnology, Universidad de Leon. España, 2008

Experiencia Académica

  •   Assistant Professor Full Time

    Universidad de Chile

    Faculty of Sciences

    Santiago, Chile

    2009 - 2019

  •   Associate Professor Full Time

    UNIVERSIDAD DE CHILE

    Faculty of Sciences

    Santiago, Chile

    2019 - A la fecha

  •   Ayudante Part Time

    Universidad de Leon

    Faculty of Sciences

    León, España

    2017 - 2018

Experiencia Profesional

  •   Academic Full Time

    University of Chile

    Santiago, Chile

    2009 - A la fecha

Formación de Capital Humano


Marlene Henríquez Urrutia (2015). Master's Thesis in Biological Sciences, Universidad de Chile. "Detection and characterization of the secondary metabolites of Penicillium roqueforti associated with the expression of a polyketide synthase".

Mauricio Jose Rozas Painemilla (2019). Seminar Title, Environmental Chemistry. "Identification of secondary metabolites with biological activity biosynthesized by the Antarctic fungal strain Pseudogymnoascus sp. 071209-E2-C3-CA "

Felipe Andrés Vega Silva (2016). Seminar Title, Engineering in Molecular Biotechnology, University of Chile. "Development of molecular tools for the study of the biosynthetic clusters of PKS and NRPS in the Antarctic fungus Pseudogymnoascus sp. 131209-E2A-C5II-EB"

Karen Alejandra Toro Tasso (2015). Seminar Title, Degree in Chemistry, University of Chile. "Isolation and identification of secondary metabolites produced by the Antarctic strain Trichocladium sp."

Marcelo Flores Catalán (2014). Seminar Title, Degree in Chemistry, University of Chile. "Analysis of the ability to produce bioactive compounds of two Antarctic fungal strains _Geomyces sp."

Marlene Henríquez Urrutia (2013). Seminar Title, Engineering in Molecular Biotechnology, University of Chile. " Fungal biodiversity associated with Antarctic marine sponges and their potential as producers of bioactive secondary metabolites"

Luis Ignacio Figueroa Gómez (2013). Undergraduate thesis, Biochemistry, University of Chile. "Purification of bioactive secondary metabolites of filamentous fungi isolated from Antarctic marine sponges."

Ivanna Araya Hormazabal (2013). Seminar Title, Degree in Chemistry, University of Chile. "Purification and characterization of secondary metabolites from the Antarctic strain Penicillium sp. 071209-E4-C5 "

Francisco Salgado (2013). Seminar Title, Degree in Chemistry, University of Chile. "Biotransformation of muelin-oic acid 11,13-dien-20-acid with different strains of Penicillium roqueforti."


Premios y Distinciones

  •   Best Poster

    Federation of European Microbiologist

    Alemania, 2013

    Award to the Best Poster- 5th Congress of European Microbiologists 2013.


 

Article (35)

Fungal Planet Description Sheets: 951-1041
Genetic Transformation of the Filamentous Fungus Pseudogymnoascus verrucosus of Antarctic Origin
Cold-active pectinolytic activity produced by filamentous fungi associated with Antarctic marine sponges
Heterologous expression, purification and characterization of a highly thermolabile endoxylanase from the Antarctic fungus Cladosporium sp.
The developmental regulator Pcz1 affects the production of secondary metabolites in the filamentous fungus Penicillium roqueforti
Heterotrimeric G protein alpha subunit controls growth, stress response, extracellular protease activity and cyclopiazonic acid production in Penicillium camemberti
Role of sfk1 Gene in the Filamentous Fungus Penicillium roqueforti
The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti
The biosynthetic gene cluster for andrastin A in Penicillium roqueforti
The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons.
Identification and functional analysis of the mycophenolic acid gene cluster of Penicillium roqueforti
Identification and Functional Analysis of the Mycophenolic Acid Gene Cluster of Penicillium roqueforti
3-Nitroasterric Acid Derivatives from an Antarctic Sponge-Derived Pseudogymnoascus sp. Fungus
3-Nitroasterric Acid Derivatives from an Antarctic Sponge-Derived Pseudogymnoascus sp. Fungus
Filamentous fungi from extreme environments as a promising source of novel bioactive secondary metabolites
Filamentous fungi from extreme environments as a promising source of novel bioactive secondary metabolites
The pcz1 Gene, which Encodes a Zn(II)(2)Cys(6) Protein, Is Involved in the Control of Growth, Conidiation, and Conidial Germination in the Filamentous Fungus Penicillium roqueforti
The pcz1 gene, which encodes a Zn(II)2Cys6 protein, is involved in the control of growth, conidiation, and conidial germination in the filamentous fungus Penicillium roqueforti
Cold-Active Xylanase Produced by Fungi Associated with Antarctic Marine Sponges
Diversity of cultivable fungi associated with Antarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential
Leucosporidium escuderoi f.a., sp nov., a basidiomycetous yeast associated with an Antarctic marine sponge
Cultivable psychrotolerant yeasts associated with Antarctic marine sponges
Rhodotorula portillonensis sp nov., a basidiomycetous yeast isolated from Antarctic shallow-water marine sediment
Glucose-induced production of a Penicillium purpurogenum xylanase by Aspergillus nidulans
Motifs in the C-terminal region of the Penicillium chrysogenum ACV synthetase are essential for valine epimerization and processivity of tripeptide formation
A preparative method for the purification of isopenicillin N from genetically blocked Acremonium chrysogenum strain TD189: studies on the degradation kinetics and storage conditions
Biotransformation of Stypotriol triacetate by Aspergillus niger
NEW BUTYROLACTONE FROM A MARINE-DERIVED FUNGUS ASPERGILLUS SP
Production of a heterologous recombinant protein using fragments of the glyceraldehyde-3-phosphate dehydrogenase promoter from Penicillium camemberti
Characterization of a novel peroxisome membrane protein essential for conversion of isopenicillin N into cephalosporin C
Diterpenoids from Azorella madreporica and Their Antibacterial Activity
Evaluation of properties of several cheese-ripening fungi for potential biotechnological applications
Molecular characterization of a fungal gene paralogue of the penicillin penDE gene of Penicillium chrysogenum
Molecular characterization of the niaD and pyrG genes from Penicillium camemberti, and their use as transformation markers
The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production

Proyecto (8)

GENOME MINING FOR NOVEL NATURAL PRODUCTS DISCOVERY FROM AN ANTARCTIC FUNGAL STRAIN
Identification of new fungal species from Antarctic marine sponges
Producción de pigmentos naturales con propiedades antioxidantes a partir de cepas antárticas del hongo filamentoso Epicoccum sp.
SEARCH AND CHARACTERIZATION OF NEW GENES DOWNSTREAM FROM THE ALPHA SUBUNIT OF HETEROTRIMERIC G PROTEINS PUTATIVELY INVOLVED IN DEVELOPMENT, PHENOTYPE AND PRODUCTION OF SECONDARY METABOLITES IN PENICILLIUM ROQUEFORTI
Búsqueda de actividades enzimáticas con potencial biotecnológico, en hongos filamentosos y levaduras aisladas desde esponjas marinas Antárticas de Bahía Fildes (isla Rey Jorge).
Bioactive compounds obtained from new fungi isolated from Antarctic marine sponges
Academia support of bioorganic chemistry area
Beta-lactam biosynthesis by Penicillium chrysogenum
35
Inmaculada Vaca

Associate Professor

Chemistry Department

UNIVERSIDAD DE CHILE

Santiago, Chile

10
Renato Chavez

Full Professor

Biology

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

5
Carlos Areche

ASSOCIATE PROFESSOR

CHEMISTRY

UNIVERSIDAD DE CHILE

Santiago, Chile

5
Carlos Gil

Docente Adjunto

Estudios interdisciplinarios

Universidad Mayor de Chile

Santiago de Chile, Chile

5
Juana Rovirosa

Professor Ad. Honorem

Ciencias

Facultad de Ciencias y Recursos Naturales

Punta Arenas, Chile

5
Gloria Levican

Académica Profesora Titular

Departamento de Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

4
AURELIO SAN MARTIN

Profesor Asociado (media jornada)

de Ciencias y Recursos Naturales

FACULTAD DE CIENCIAS

Punta Arenas, Chile

2
Mario Silva

Emeritus Professor

Botany Department

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
KATHERINNE NAVARRETE

PhD student

King's College London

Chile

1
Leonora Mendoza

Académico JC

Departamento de Química de los Materiales

Universidad de Santiago de Chile

Santiago, Chile

1
Rubén Polanco

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO (UNAB)

SANTIAGO, Chile

1
María Ravanal

Académico

Universidad Austral de Chile

Valdivia, Chile

1
Luis Larrondo

Associate Professor

Genetica Molecular y Microbiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Exequiel Medina

Researcher

BIología

Universidad de Chile

Santiago, Chile

1
Lorena Rosa

PhD

Departamento de Patología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
María Vargas

Postdoctoral

Departamento de Química

Laboratorio de Microbiología Molecular y Biotecnología Ambiental

Valparaíso, Chile

1
Jorge Soto

Profesor Asistente

Departamento de Ciencias Quimicas

Universidad Andrés Bello

Viña del Mar, Chile

1
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
Alejandra Goity

Investigador postdoctoral iBio

Genética Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile