Man

Romina Victoria Sepúlveda Sepúlveda

Profesor Investigador

Universidad Andrés Bello

Santiago, Chile

Líneas de Investigación


Mis lineas de investigación estan dedicadas a resolver problemas biológicos con estrategias computacionales. Especificamente en el área de simulación molecular de complejos proteína-proteína y caracterización de membranas prebioticas.

Educación

  •  Bioinformática, UNIVERSIDAD ANDRES BELLO. Chile, 2018

Experiencia Académica

  •   FONDECYT Postdoctorado Full Time

    UNIVERSIDAD ANDRES BELLO

    Ciencias Biologicas

    Santiago, Chile

    2020 - A la fecha

Experiencia Profesional

  •   PostDoc FONDEF ID19I10160 Full Time

    UNAB

    Santiago, Chile

    2020 - 2020

  •   Senior Bioinformatician Full Time

    uBiome

    Santiago, Chile

    2018 - 2019

  •   Tesista doctoral Full Time

    Universidad Andres Bello

    Santiago, Chile

    2013 - 2018


 

Article (18)

The Emergence of New Catalytic Abilities in an Endoxylanase from Family GH10 by Removing an Intrinsically Disordered Region
A method for characterizing the thermal stability and antimicrobial binding to Lipopolysaccharides of Gram-negative isogenic mutant strains
A rationally designed orthogonal synthetase for genetically encoded fluorescent amino acids
Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin
The molecular nature of the 17 beta-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel beta 1 subunit
Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase
MOLECULAR DETERMINANTS OF BK CHANNEL FUNCTIONAL DIVERSITY AND FUNCTIONING
Structural determinants of 5 ',6 '-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel
?1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel
Structure-Driven Pharmacology of Transient Receptor Potential Channel Vanilloid 1
Effects of the Accessory Subunit gamma 1 on the External Architecture of BK Channel
Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel
Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels
Molecular Determinants of Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P-2) Binding to Transient Receptor Potential V1 (TRPV1) Channels
Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels
Substitutions at F380 in S6 by Small Hydrophobic Amino Acids Makes the Opening Transition in BK Channels Rate Limiting
Turning a Small into Large Conductance K-Channel - How Far Can We Go?
K+ Conduction and Mg2+ Blockade in a Shaker Kv-Channel Single Point Mutant with an Unusually High Conductance

Abstract (4)

Thermal Diffusion Pathways of TRPV1
17 beta-Estradiol Binds and Modulates BK Channel through its beta 1 Auxiliary Subunit
Structural Characterization of Ligand-Specific Interactions in TRPV1 Channel: Gating Mechanism by Capsaicin and Capsazepine
Rational discovery of new capsaicin analogues as TRPV1 activators
22
Romina Sepúlveda

Profesor Investigador

Facultad de Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

11
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

6
ramon latorre

Profesor

Instituto de Neurociencia

Universidad de Valparaíso

5, Chile

3
Ignacio Diaz

Profesor asistente

Centro e Bioinformatica y Biologia Integrativa

Universidad Andrés Bello

Santiago, Chile

2
Daniel Aguayo

Assistant Professor

Molecular Biophysics & Bioinformatics Group

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
David Naranjo

Profesor titular

Neurociencia

Universidad de Valparaíso

VALPARAISO, Chile

1
VALERIA MARQUEZ

Profesor Asistente

Centro de Nanotecnologia Aplicada

Universidad Mayor de Chile

SANTIAGO, Chile

1
Matías Zúñiga

Postdoctorado

Centro de Bioinformática y Simulación Molecular

Universidad de Talca

TALCA, Chile

1
Horacio Poblete

Profesor Conferenciante

Universidad de Talca

Talca, Chile

1
GUSTAVO CONTRERAS

Centro Interdisciplinario de Neurociencias de Valparaíso

Valparaiso, Chile

1
Pablo Olivero

Profesor Adjunto

Patologia y Fisiologia

Universidad de Valparaiso

Viña del Mar, Chile

1
Karen Castillo

Investigadora

Laboratorio de Sensores Moleculares, Centro Interdisciplinario de Neurociencia de Valparaíso (CINV), Facultad de Ciencias, Universidad de Valparaíso

Valparaiso, Chile

1
Jimmy Stehberg

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

1
Juan Castillo

lecturer

physics department

Universidad de Santiago de Chile

santiago, Chile

1
Nieves Navarro

Lab Manager

Biología Molecular

Centro interdisciplinario de neurociencia de Valparaíso

Valparaíso, Chile