Man

Francisca Andrea Alcayaga Miranda

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

Líneas de Investigación


Cell Therapy, stem cells, regenerative medicine, extracellular vesicles, exosomes, cancer, angiogenesis

Educación

  •  Veterinaria, Universidad Autonoma de Barcelona. España, 2009
  •  Medico Veterinario, Universidad Mayor. Chile, 2002

Experiencia Académica

  •   Profesor Instructor Full Time

    Universidad de los Andes

    Medicina

    Santiago, Chile

    2011 - A la fecha

Experiencia Profesional

  •   Profesor Instructor Full Time

    Universidad de los Andes

    Chile

    2011 - A la fecha

  •   Investigador Senior Full Time

    Cells for Cells

    Santiago, Chile

    2011 - A la fecha

Formación de Capital Humano


DIRECCIÓN DE TESIS PRE- Y POST-GRADO
2013-2014: Antonella Rossati. Tesis. Veterinaria. Universidad de Viña del Mar. Director de Tesis.
2012-2014: Diego Seguel. Tesis. Ingeniería en Biotecnología. USACH. Co-Director de Tesis.
2020-2021: Nicolas Georges. Tesis. Ingeniería en Biotecnología. UTEM. Director de Tesis
2020-2021: Darío Donoso Meneses. Tesis. Bioquímica. Universidad de Chile. Director de Tesis



 

Article (17)

A Chemically Defined, Xeno- and Blood-Free Culture Medium Sustains Increased Production of Small Extracellular Vesicles From Mesenchymal Stem Cells
Camouflage strategies for therapeutic exosomes evasion from phagocytosis
Exosomes on the border of species and kingdom intercommunication
Stem cell exosomes inhibit angiogenesis and tumor growth of oral squamous cell carcinoma
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial
The Reparative Abilities of Menstrual Stem Cells Modulate the Wound Matrix Signals and Improve Cutaneous Regeneration
Antimicrobial Activity of Mesenchymal Stem Cells: Current Status and New Perspectives of Antimicrobial Peptide-Based Therapies
Safety and Efficacy of the Intravenous Infusion of Umbilical Cord Mesenchymal Stem Cells in Patients With Heart Failure A Phase 1/2 Randomized Controlled Trial (RIMECARD Trial [Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy])
Harnessing the Angiogenic Potential of Stem Cell-Derived Exosomes for Vascular Regeneration.
Prostate tumor-induced angiogenesis is blocked by exosomes derived from menstrual stem cells through the inhibition of reactive oxygen species
The Immunosuppressive Signature of Menstrual Blood Mesenchymal Stem Cells Entails Opposite Effects on Experimental Arthritis and Graft Versus Host Diseases
Characterization of menstrual stem cells: angiogenic effect, migration and hematopoietic stem cell support in comparison with bone marrow mesenchymal stem cells.
Chorion Mesenchymal Stem Cells Show Superior Differentiation, Immunosuppressive, and Angiogenic Potentials in Comparison With Haploidentical Maternal Placental Cells
Combination therapy of menstrual derived mesenchymal stem cells and antibiotics ameliorates survival in sepsis
The promising potential of menstrual stem cells for antenatal diagnosis and cell therapy.
Minimal RB-responsive E1A promoter modification to attain potency, selectivity, and transgene-arming capacity in oncolytic adenoviruses.
Osteosarcoma cells as carriers to allow antitumor activity of canine oncolytic adenovirus in the presence of neutralizing antibodies.

Abstract (1)

CONDITIONAL IMMUNOSUPRESSIVE PROPERTY OF MENSTRUAL BLOOD-DERIVED STEM CELLS IN VITRO

Proyecto (9)

Investigating the effect of MAVs-enriched mitochondrial transplantation on intracellular antiviral immunity and their restorative and immunomodulatory effects in a viral-induced acute lung injury model
INVESTIGATING THE IMMUNOREGULATORY AND ANTI-RHEUMATOID ARTHRITIS ACTIVITIES OF SMALL EXTRACELLULAR VESICLES-SHUTTLED BIOACTIVE MICRORNA DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM CELL
Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue
Desarrollo y validación de un producto celular alogénico derivado de células madre estromales para su uso en síndrome de distrés respiratorio agudo
Exospand=> suplemento humano para expansión de células progenitoras hematopoyéticas
REGENERO The Chilean Stem Cell Consortium
‘Evaluación del efecto anti- tumoral de las MSC-derivadas del fluido menstrual (MenSC) en un sistema de cocultivo’
Investigando las propiedades inmunomodulatorias de una nueva población stem cell de fluido menstrual recientemente caracterizada y exploración de su aplicación potencial en enfermedades inflamatorias’
Investigating the anti-angiogenic effect of exosome-mediated delivery of functionally active miRNA-149-3p,145-5p and 6131 to tumor tissue
13
Francisca Alcayaga

Profesor Asociado

Facultad de Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

7
Maroun Khoury

Professor

Faculty of Medicine

Universidad de Los Andes

santiago, Chile

5
Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile

2
Fernando Figueroa

Director

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago de Chile, Chile

2
Fernando Ezquer

Full Professor

Center for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

2
Aliosha Figueroa

Asistente de Investigación

Consorcio Regenero S.A.

Santiago, Chile

1
María Cádiz

JEFA DE PRODUCCIÓN

PRODUCCIÓN

CELLS FOR CELLS S.A.

SANTIAGO, Chile

1
Mónica Kurte

Investigador

Laboratorio de Inmunologìa

Universidad de los Andes

Santiago, Chile

1
Fernando Verdugo

Residente

Cardiologia

Clinica Las Condes

Santiago, Chile

1
Francisco Espinoza

Profesor Asistente

Medicina Interna

Universidad de los Andes

Santiago, Chile

1
Christina Schuh

Assistant Professor

Centre for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

1
Mario Orrego

Académico

Traumatología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
José Matas

Jefe Departamento de Traumatologia

Traumatologia

Universidad de Los Andes

Santiago, Chile

1
Yessia Hidalgo

Flow Facility manager

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

1
Valentina Castillo

Estudiante de Doctorado

Ingeniería

Pontificia Universidad Católica de Chile

Santiago, Chile