Man

Jaime Adolfo Valderrama Guerrero

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Líneas de Investigación


Quinone Chemistry; Bioactive Natural Products; Medicinal Chemistry; Química de Quinonas; Química Heterocíclica; Química Médica


 

Article (18)

Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells
An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities
Gastroprotective Effect and Cytotoxicity of Labdeneamides with Amino Acids
Redox-Active Quinones and Ascorbate: An Innovative Cancer Therapy That Exploits the Vulnerability of Cancer Cells to Oxidative Stress
Studies on quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents
The solar-chemical photo-Friedel-Crafts heteroacylation of 1,4-quinones
Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents
Studies on quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimidoisoquinolinequinones
Part 2: Influence of 2-Euryfuryl-1,4-naphthoquinone and Its peri-Hydroxy Derivatives on Both Cell Death and Metabolism of TLT Cells, a Murine Hepatoma Cell Line. Modulation of Cytotoxicity by Vitamin C
Regiochemical control in the amination reaction of phenanthridine-7,10-quinones
Studies on quinones. Part 45: Novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines
Synthesis and antitumor evaluation of 8-phenylaminopyrimido[4,5-c]isoquinolinequinones
Synthesis and Antitumor Evaluation of Thiophene Analogs of Kigelinone
Design and synthesis of angucyclinone AB-pyrido[2,3-d] pyrimidine analogues
Part 1: Effect of vitamin C on the biological activity of two euryfurylbenzoquinones on TLT, a murine hepatoma cell line
Studies on quinones. Part 42: Synthesis of furylquinone and hydroquinones with antiproliferative activity against human tumor cell lines
Studies on quinones. Part 43: Synthesis and cytotoxic evaluation of polyoxyethylene-containing 1,4-naphthoquinones
Studies on quinones. Part 44: Novel angucyclinone N-heterocyclic analogues endowed with antitumoral activity

Review (1)

Molecular Chaperone Hsp90 as a Target for Oxidant-Based Anticancer Therapies
19
Jaime Valderrama

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

9
Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

6
Pedro Buc

Profesor titular

Quimica y Farmacia

UNIVERSITE CATHOLIQUE DE LOUVAIN

Iquique, Chile

5
David Vásquez

Profesor Asistente

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Juana Ibacache

académico

Ciencias del ambiente

Universidad de Santiago de Chile

Santiago, Chile

2
Leonel Rojo

Profesor Asociado

Departamento de Biología

Universidad de Santiago de Chile

Estación Central, Chile

1
Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

1
Veronica Arancibia

Profesor horas

Quimica Inorganica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Patricia Diaz

Academic

University of Connecticut Health Center

Farmington, CT, Estados Unidos