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Guillermo Schmeda Hirschmann

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

Natural Products Chemistry; Biological activity of naturally occurring compounds and semisynthetic derivatives; Ethnopharmacology; Biodiversity; Food Chemistry

Bioquímico, Universidad Nacional de Asuncion, Paraguay. Paraguay, 1978
Organic Chemistry, TECHNISCHE UNIVERSITAT BERLIN. Alemania, 1984

Profesor Investigador Full Time

Universidad Nacional de Asunción, Paraguay

Facultad de Ciencias Químicas

Asunción (San Lorenzo), Paraguay

1981 - 1989
Asesor Científico Part Time

Universidad Nacional de Asunción, Paraguay

Facultad de Ciencias Veterinarias

Asunción (San Lorenzo), Paraguay

1987 - 1989
Profesor Titular Full Time

Universidad de Talca

Talca, Chile

1989 - A la fecha

Microbiólogo Full Time

Cervecería Paraguaya S.A.

Asunción, Paraguay

1978 - A la fecha

Dirección de Tesis de Doctorado finalizadas: 8
Co-dirección de Tesis de Doctorado finalizadas: 4
Dirección de Tesis de Doctorado y Magister 2014-2017: Doctorado: 1 finalizada, dos en ejecución; Magister: dos completadas (una como Director, otra como co-Director).
Los doctorandos que se encuentran realizando sus Tesis, así como los nuevos alumnos de Doctorado que iniciarán actividades este año, investigan distintos aspectos de la relación entre composición, identidad de componentes y bioactividad en alimentos sudamericanos. La investigación incluye chemical profiling, identificación de compuestos bioactivos, mecanismos de acción de extractos y compuestos en distintos modelos biológicos in vitro y en cultivos de células humanas.

COLABORACIONES en PUBLICACIONES RECIENTES

Thomas Efferth, Abteilungsleiter, Johannes Gutenberg-Universität, Institut für Pharmazie, D-55128 Mainz, Alemania

Camille Oger, Thierry Durand, Institut des Biomolécules Max Mousseron, IBMM, UMR 5247, University of Montpellier, CNRS, ENSCM, Montpellier, France

Ángel Gil-Izquierdo, Raúl Domínguez-Perles, Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), University Campus of Espinardo, Edif. 25, 30100, Murcia, Spain

Luis Bustamante, Claudia Mardones, Departamento de Análisis Instrumental, Facultad de Farmacia, Universidad de Concepción, Chile

Katherine Márquez, David Contreras, Biotechnology Centre and Chemical Sciences Faculty, University of Concepcion, Concepcion, Chile

Ana Ladio, Laboratorio Ecotono, INIBIOMA (CONICET), Universidad Nacional del Comahue, Bariloche, Río Negro, Argentina

Jaume Bastida, Grup de Productes Naturals, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain

Laura Edith Alché, Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428BGA Buenos Aires, Argentina

María Inés Isla (F. Cattaneo, M.S. Costamagna, I.C. Zampini, J. Sayago, M.R. Alberto, V. Chamorro, A. Pazos), INQUINOA (CONICET), 4000 S.M. de Tucumán, Tucumán, Argentina, Fundación Miguel Lillo, 4000 S.M. de Tucumán, Tucumán, Argentina

Felix A. Urra, Cesar Cardenas, Programa de Anatomía y Biología del Desarrollo, Instituto de Ciencias Biomedicas (ICBM), Facultad de Medicina, Universidad de Chile and Geroscience Center for Brain Health and Metabolism, Santiago, Chile

Nibaldo C. Inestrosa, Juan M. Zolezzi, Centro de Envejecimiento y Regeneracion (CARE), Departamento de Biologia Celular y Molecular, Facultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile

AvH Stipendium

ALEXANDER VON HUMBOLDT FOUNDATION

Alemania, 1996

Research on microbial metabolites and biotechnology, Kaiserslautern. Germany


Antiviral effect of natural and semisynthetic diterpenoids against adenovirus infection in vitro. Bidart, J.E., Pertino, M.W., Schmeda-Hirschmann, G., Alché, L.E., Petrera, E. Article PLANTA MEDICA (2023)
Chemical profile and bioactivity of Chilean bean landraces (Phaseolus vulgaris L.). Nina, N., Theoduloz, C., Paillán, H., Jiménez-Aspee, F., Márquez, K., Schuster, K., Becker, L., Oellig, C., Frank, J., Schmeda-Hirschmann, G. Article Journal of Fuctional Foods (2023)
Inhibition of platelet aggregation by extracts and compounds from leaves of Chilean bean landraces (Phaseolus vulgaris L.) Fuentes, E., Rodríguez, L., Méndez, D., Alarcón-Espósito, J., Nina, N., Burgos-Edwards, A., Carrasco, B., Palomo, I., Schmeda-Hirschmann, G. Article JOURNAL OF FUNCTIONAL FOODS (2023)
Leaf development in Chilean bean landraces (Phaseolus vulgaris) affects phenolic composition and α-glucosidase inhibition. Burgos-Edwards, A., Theoduloz, C., Márquez, K., Carrasco, B., Schmeda-Hirschmann, G. Article SCIENTIA HORTICULTURAE (2023)
A Paraguayan toad Rhinella schneideri preparation based on Mbya tradition increases mitochondrial metabolism with migrastatic effects on breast cancer cells. Schmeda-Hirschmann, G., Burgos-Edwards, A., Rojas de Arias, A., López-Torres, C., Palominos, C., Fuentes-Retamal, S., Herrera, Y., Urra, F.A. Article JOURNAL OF ETHNOPHARMACOLOGY (2022)
Are fruit surface differences in two blueberry cultivars major drivers of contrasting postharvest dynamics? Moggia, C., Lara, I., Jordi Graell, J., Schmeda-Hirschmann, G., Thomas-Valdés, S., Gustavo A. Lobos, G.A. Article HORTICULTURAE (2022)
Arylated analogues of cypronazole: fungicidal efect and activity on human fibroblasts. Docking analysis and molecular dynamics simulations. Herrera-Cano, N., Andujar, S.A., Theoduloz, C., Wunderlin, D.A., Santiago, A.N., Schmeda Hirschmann, G., Enriz, R.D., Feresin, G.E. Article Natural Products and Bioprospecting (2022)
Clinal vs. disruptive latitudinal variation in fruit traits of a South American mistletoe. Amico, G.C., Di Virgilio, A., Schmeda-Hirschmann, G., Aizen, M.A. Article OECOLOGIA (2022)
Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces. Avila, F., Cruz, N., Alarcon-Espósito, J., Nina, N., Paillan, H., Marquez, K., Fuentealba, D., Burgos-Edwards, A., Theoduloz, C., Vejar-Vivar, C., Schmeda-Hirschmann, G. Article JOURNAL OF FUNCTIONAL FOODS (2022)
Iridoids and polyphenols from chilean Gaultheria spp. berries decrease the glucose uptake in Caco-2 cells after simulated gastrointestinal digestion Mieres-Castro, Daniel; Theoduloz, Cristina; Sus, Nadine; Burgos-Edwards, Alberto; Schmeda-Hirschmann, Guillermo; Frank, Jan; Jimenez-Aspee, Felipe Article ISI FOOD CHEMISTRY (2022)
Phenolic Composition and alpha-Glucosidase Inhibition of Leaves from Chilean Bean Landraces Alarcon-Esposito, Jazmin; Nina, Nelida; Theoduloz, Cristina; Burgos-Edwards, Alberto; Paillan, Hernan; Schmeda-Hirschmann, Guillermo Article ISI PLANT FOODS FOR HUMAN NUTRITION (2022)
The use of medicinal plants by Paraguayan migrants in the Atlantic Forest of Misiones, Argentina, is based on Guarani tradition, colonial and current plant knowledge Kujawska, Monika; Schmeda-Hirschmann, Guillermo Article ISI JOURNAL OF ETHNOPHARMACOLOGY (2022)
Antiglycating Effect of Phenolics from the Chilean Currant Ribes cucullatum under Thermal Treatment Avila, Felipe; Ravello, Natalia; Manriquez, Camila; Jimenez-Aspee, Felipe; Schmeda-Hirschmann, Guillermo; Theoduloz, Cristina Article ISI ANTIOXIDANTS (2021)
Improving Fruit Quality, Bioactive Compounds, and Storage Life of Date Palm (Phoenix dactylifera L., cv. Barhi) Using Natural Elicitors Ahmed, Zienab F. R.; Al Shaibani, Fatima Y. Y.; Kaur, Navjot; Maqsood, Sajid; Schmeda-Hirschmann, Guillermo Article ISI HORTICULTURAE (2021)
Phenolic composition, antioxidant capacity and α-glucosidase inhibitory activity of raw and boiled Chilean Araucaria araucana kernels Schmeda-Hirschmann, Guillermo; Antileo-Laurie, Javier; Theoduloz, Cristina; Jiménez-Aspee, Felipe; Avila, Felipe; Burgos-Edwards, Alberto; Olate-Olave, Verónica Article FOOD CHEMISTRY (2021)
Seasonal Variation of Plant Defense Inductor Ellagitannins in Strawberry Leaves under Field Conditions for Phytosanitary Technological Applications Grellet-Bournonville, Carlos F.; de los Angeles Di Peto, Pia; Cervino Dowling, Ana M.; Castagnaro, Atilio P.; Schmeda-Hirschmann, Guillermo; Diaz Ricci, Juan C.; Mamani, Alicia, I; Filippone, Maria P. Article ISI JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)
Synergistic Effect of Preharvest Spray Application of Natural Elicitors on Storage Life and Bioactive Compounds of Date Palm (Phoenix dactylifera L., cv. Khesab) Ahmed, Zienab F. R.; Alblooshi, Shamsa S. N. A.; Kaur, Navjot; Maqsood, Sajid; Schmeda-Hirschmann, Guillermo Article ISI HORTICULTURAE (2021)
Bioactive constituents from South American Prosopis and their use and toxicity. Schmeda-Hirschmann, G., Theoduloz, C., Jiménez-Aspee, F., Echeverría, J Article CURRENT PHARMACEUTICAL DESIGN (2020)
Cyclic dipeptides from the Chilean hazelnut cotyledons (Gevuina avellana Mol., Proteaceae). Schmeda Hirschmann, G., de Andrade, J.P., Jiménez-Aspee, F., Mieres-Castro, D. Article SCIENTIFIC REPORTS (2020)
Effects of gastrointestinal digested polyphenolic enriched extracts of Chilean currants (Ribes magellanicum and Ribes punctatum) on in vitro fecal microbiota Burgos-Edwards, A; Fernandez-Romero, A; Carmona, M; Thuissard-Vasallo, I; Schmeda-Hirschmann, G; Larrosa, M Article WOS ex (ISI). FOOD RESEARCH INTERNATIONAL (2020)
Integral use of Argentinean Solanum betaceum red fruits as functional food ingredient to prevent metabolic syndrome: effect of in vitro simulated gastroduodenal digestion Orqueda M.E.; Torres S.; Zampini, I.C.; Cattaneo F.; Di Pardo A.F.; Valle E.M.; JimÃ©nez-Aspee F.; Schmeda-Hirschmann G.; Isla, M.I. Article SCOPUS Heliyon (2020)
Iridoids and Amino Acid Derivatives from the Paraguayan Crude Drug Adenocalymma marginatum (ysypo hu) Schmeda-Hirschmann G.; Burgos-Edwards A.; JimÃ©nez-Aspee F.; Mieres-Castro D.; Theoduloz C.; Pormetter L.; Fogel R.; CÃ©spedes C.; Soria N.; Valdez S. Article ISI SCOPUS MOLECULES (2020)
Isolation and characterization of secondary metabolites from Gaultheria tenuifolia berries. Mieres-Castro, D., Schmeda-Hirschmann, G., Theoduloz, C., Rojas, A., Piderit, D., Jiménez-Aspee, F. Article JOURNAL OF FOOD SCIENCE (2020)
Phenolics from the Bolivian highlands food plant Ombrophytum subterraneum (Aspl.) B. Hansen (Balanophoraceae): Antioxidant and α-glucosidase inhibitory activity Nelida, N; Theoduloz, C; Gimenez, A; Schmeda-Hirschmann, G Article WOS (ex ISI) FOOD RESEARCH INTERNATIONAL (2020)
Synthesis, trypanocidal and anti-leishmania activity of new triazole-lapachol and nor-lapachol hybrids Walter Pertino, Mariano; de la Torre, Alexander F.; Schmeda-Hirschmann, Guillermo; Vega, Celeste; Rolon, Miriam; Coronel, Cathia; de Arias, Antonieta Rojas; Leal Lopez, Karla; Carranza-Rosales, Pilar; Viveros Valdez, Ezequiel Article ISI BIOORGANIC CHEMISTRY (2020)
The Parotoid Gland Secretion from Peruvian Toad Rhinella horribilis (Wiegmann, 1833): Chemical Composition and Effect on the Proliferation and Migration of Lung Cancer Cells Schmeda-Hirschmann, Guillermo; de Andrade, Jean Paulo; Soto-Vasquez, Marilu Roxana; Alvarado-Garcia, Paul Alan Arkin; Palominos, Charlotte; Fuentes-Retamal, Sebastian; Mellado, Mathias; Correa, Pablo; Urra, Felix A. Article ISI TOXINS (2020)
Fabiana imbricata Ruiz et Pav. (Solanaceae), a review of an important Patagonian medicinal plant. Schmeda-Hirschmann, G., Theoduloz, C. Article JOURNAL OF ETHNOPHARMACOLOGY (2019)
An efficient cyclization of Lapachol to new benzo[h]chromene hybrid compounds: Tandem vs one-pot esterification-click (CuAAC) study. de la Torre, A.F., Ali, A., Westermann, B., Schmeda-Hirschmann, G., Pertino, M.W. Article New Journal of Chemistry (2019)
Andean Prumnopitys Andina (Podocarpacae) Fruit Extracts: Characterization of Secondary Metabolites and Potential Cytoprotective Effect Jimenez-Aspee, Felipe; THEODULOZ, CRISTINA; Pormetter, Lisa; Mettke, Judith; Avila, Felipe; Schmeda-Hirschmann, Guillermo Article ISI SCOPUS MOLECULES (2019)
Anti-inflammatory effect of polyphenols from Chilean currants (Ribes magellanicum and R. punctatum) after in vitro gastrointestinal digestion on Caco-2 cells. Burgos-Edwards, A., Martín Pérez, L., Jiménez-Aspee, F., Theoduloz, C., Schmeda Hirschmann, G., Larrosa, M. Article JOURNAL OF FUNCTIONAL FOODS (2019)
Antioxidant activity and isolation of polyphenols and new iridoids from Chilean Gaultheria phillyreifolia and G. poeppigii berries Mieres-Castro, D., Schmeda-Hirschmann, G., Theoduloz, C., Gómez-Alonso, S., Pérez Navarro, J., Márquez, K., Jiménez-Aspee, F. Article ISI, SCOPUS FOOD CHEMISTRY (2019)
Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms Abdelfatah S.; Lu X.; Schmeda-Hirschmann G.; Efferth T. Article ISI SCOPUS JOURNAL OF ETHNOPHARMACOLOGY (2019)
Effect of simulated gastrointestinal digestion on polyphenols and bioactivity of the native Chilean red strawberry (Fragaria chiloensis ssp. chiloensis f. patagonica) Thomas-Valdes, S; Theoduloz, C; Jimenez-Aspee, F; Schmeda-Hirschmann, G Article WOS (ex ISI). FOOD RESEARCH INTERNATIONAL (2019)
Male sexual enhancers from the Peruvian Amazon. Schmeda-Hirschmann, G., Burgos-Edwards, A., Theoduloz, C., Jiménez-Aspee, F., Vargas-Arana, G. Article Journal of Ethnopharmacology (2019)
Patagonian berries as native food and medicine. Schmeda-Hirschmann, G., Jimenez-Aspee, F., Theoduloz, C., Ladio, A.H. Article JOURNAL OF ETHNOPHARMACOLOGY (2019)
Phenolic, oxylipin and fatty acid profiles of the Chilean hazelnut (Gevuina avellana): Antioxidant activity and inhibition of pro-inflammatory and metabolic syndrome-associated enzymes Ramos, LLP; Jimenez-Aspee, F; Theoduloz, C; Burgos-Edwards, A; Dominguez-Perles, R; Oger, C; Durand, T; Gil-Izquierdo, A; Bustamante, L; Mardones, C; Marquez, K; Contreras, D; Schmeda-Hirschmann, G Article WOS ex (ISI). FOOD CHEMISTRY (2019)
Polyphenol Composition and (Bio)Activity of Berberis Species and Wild Strawberry from the Argentinean Patagonia Chamorro M.F.; Reiner G.; Theoduloz C.; Ladio A.; Schmeda-Hirschmann G.; GÃ³mez-Alonso S.; JimÃ©nez-Aspee F. Article ISI SCOPUS MOLECULES (2019)
Tetraglochin andina Ciald.: a medicinal plant from the Argentinean highlands with potential use in vaginal candidiasis. Moreno, M.A., Córdoba, S., Zampini, I.C., Alberto, M.R., Mercado, M.I., Nader-Macias, M.E.F., Sayago, J., Burgos-Edwards, A., Schmeda-Hirschmann, G., Isla, M.I. Article JOURNAL OF ETHNOPHARMACOLOGY (2018)
Argentinean Larrea dry extracts with potential use in vaginal candidiasis. Moreno, M.A., Córdoba, S., Zampini, I.C., Mercado, M.I., Ponessa, G., Sayago, J.E., Pino R., L.L., Schmeda-Hirschmann, G., Isla, M.I. Article Natural Products Communications (2018)
Changes in polyphenol composition and bioactivity of the native Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) after in vitro gastrointestinal digestion Thomas-Valdes, S; Theoduloz, C; Jimenez-Aspee, F; Burgos-Edwards, A; Schmeda-Hirschmann, G Article WOS (ex ISI) FOOD RESEARCH INTERNATIONAL (2018)
Cholinesterase inhibition activity, alkaloid profiling and molecular docking of Chilean Rhodophiala (Amaryllidaceae). Tallini, L.R., Bastida, J., Cortes, N., Osorio, E.H., Theoduloz, C., Schmeda-Hirschman, G. Article ISI MOLECULES (2018)
Colonic fermentation of polyphenols from Chilean currants (Ribes spp.) and its effect on antioxidant capacity and metabolic syndrome-associated enzymes Burgos-Edwards, A.; Jimenez-Aspee, F.; Theoduloz, C.; Schmeda-Hirschmann, G Article WOS (ex ISI). FOOD CHEMISTRY (2018)
Effect of polyphenols from wild Chilean currants (Ribes spp.) on the activity of intracellular antioxidant enzymes in human gastric AGS cells. Jimenez-Aspee, F., Theoduloz, C., Burgos-Edwards; A., Schmeda-Hirschmann, G. Article Food Bioscience (2018)
Electrosprayed chitosan microcapsules as delivery vehicles for vaginal phytoformulations Moreno, M.A., Gómez-Mascaraque, L.G., Arias, M., Zampini, I.C., Sayago, J.E., Pino R., L.L., Schmeda-Hirschmann, G., López-Rubio, A., Isla, M.I. Article ISI CARBOHYDRATE POLYMERS (2018)
Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: in vitro and in silico studies. Theoduloz, C., Alzate-Morales, J., Jiménez-Aspee, F., Isla, M.I., Alberto, M.R., Pertino, M.W., Schmeda-Hirschmann, G. Article ISI Chemical Biology & Drug Design (2018)
Neuroprotective effects of ferruginol, jatrophone, and junicedric acid against amyloid-β injury in hippocampal neurons. . Zolezzi, J.M., Lindsay, C.B., Serrano, F.G., Ureta, R.C., Theoduloz, C., Schmeda-Hirschmann, G., Inestrosa, N.C. Article Journal of Alzheimer's Disease (2018)
Polyphenolic profile and antioxidant activity of meristem and leaves from "chagual" (Puya chilensis Mol.), a salad from central Chile Jimenez-Aspee, F; Theoduloz, C; Gomez-Alonso, S; Hermosin-Gutierrez, I; Reyes, M; Schmeda-Hirschmann, G Article WOS (ex ISI) FOOD RESEARCH INTERNATIONAL (2018)
Synthesis, antiviral and cytotoxic activity of novel terpenyl hybrid molecules prepared by click chemistry. . Pertino, M.W., Petrera, E., Alché, L.E., Schmeda-Hirschmann, G. Article MOLECULES (2018)
The major chromophore arising from glucose degradation and oxidative stress occurrence during lens proteins glycation induced by glucose. Ávila, F., Schmeda-Hirschmann, G., Silva, E. Article MOLECULES (2018)
Antiprotozoal Activity of Triazole Derivatives of Dehydroabietic Acid and Oleanolic Acid Pertino M.W.; Vega C.; Rolón M.; Coronel C.; De Arias A.R.; Schmeda-Hirschmann G. Article ISI SCOPUS MOLECULES (2017)
Chemical and functional characterization of seed, pulp and skin powder from chilto (Solanum betaceum), an Argentine native fruit. Phenolic fractions affect key enzymes involved in metabolic syndrome and oxidative stress Orqueda, M.E., Rivas, M., Zampini, I.C., Alberto, M.R., Torres, S., Cuello, S., Sayago, J., Thomas-Valdes, S., Jiménez-Aspee, F., Schmeda-Hirschmann, G., Isla, M.I. Article ISI SCOPUS FOOD CHEMISTRY (2017)
Chemical and functional characterization of skin, pulp and seed powder from the Argentine native fruit Mistol (Ziziphus mistol). Effects of phenolic fractions on key enzymes involved in metabolic syndrome and oxidative stress. Orqueda, M.E., Zampini, I.C., Torres, S., Alberto, M.R., Pino Ramos, L.L., Schmeda-Hirschmann, G., Isla, M.I. Article JOURNAL OF FUNCTIONAL FOODS (2017)
Cytoprotective effect mediated by polyphenols from Chilean native berries against free radical-induced damage on AGS cells. Ávila, F., Theoduloz, C., López-Alarcón, C., Dorta, E., Schmeda-Hirschmann, G. Article Oxidative Medicine and Cellular Longevity (2017)
Inhibition of of pro-inflammatory enzymes by medicinal plants from the Argentinean highlands (Puna) Torres Carro, R., Isla, M.I., Thomas-Valdes, S., Jiménez-Aspee, F., Schmeda-Hirschmann, G., Alberto, M.R. Article ISI SCOPUS JOURNAL OF ETHNOPHARMACOLOGY (2017)
Isovitexin as marker and bioactive compound in the antinociceptive activity of the Brazilian crude drug extracts of Echinodorus scaber and E. grandiflorus. Strada, C.L., da Costa Lima, K., da Silva, V.C., Ribeiro, R.V., Dores, E.F.G de C., Dall'Oglio, E.L., Schmeda-Hirschmann, G., Carollo, C.A., Martins, D.T. de O., de Sousa Junior, P.T. Article Revista Brasileira de Farmacognosia (2017)
Qualitative and quantitative changes in polyphenol composition and bioactivity of Ribes magellanicum and R. punctatum after in vitro gastrointestinal digestion Burgos-Edwards A., Jiménez-Aspee F., Thomas-Valdés S., Schmeda-Hirschmann G., Theoduloz C. Article ISI SCOPUS FOOD CHEMISTRY (2017)
The native fruit Geoffroea decorticans from the arid northern Chile: phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome associated enzymes. Jiménez-Aspee, F., Theoduloz, C., Soriano, M. del P. C., Ugalde-Arbizu, M., Alberto, M.R., Zampini, I.C., Isla, M.I., Simirgiotis, M.J., Schmeda-Hirschmann, G. Article MOLECULES (2017)
The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells Schmeda-Hirschmann, G., Burgos-Edwards, A., Rojas de Arias, A., Vega G., C., Alfonso, J., Rolon, M., Brusquetti, F., Netto, F., Urra, F.A., Cárdenas, C. Article ISI SCOPUS JOURNAL OF ETHNOPHARMACOLOGY (2017)
Antibacterial and leishmanicidal activity of Bolivian propolis. Nina, N., Lima, B., Feresin, G.E., Giménez, A., Salamanca C., E., Schmeda-Hirschmann, G. Article LETTERS IN APPLIED MICROBIOLOGY (2016)
Antifungal activities of extracts produced by liquid fermentation of Chilean Stereum species against Botrytis cinerea (grey mould agent). Aqueveque, P., Céspedes, C.L., Alarcón, J., Schmeda-Hirschmann, G., Cañumir, J.A., Becerra, J., Silva, J., Sterner, O., Radrigán, R., Aranda, M. Article CROP PROTECTION (2016)
Antioxidant activity and phenolic profiles of the wild currant Ribes magellanicum from Chilean and Argentinean Patagonia. Jiménez-Aspee, F., Valdés, S.T., Schulz, A., Ladio, A., Theoduloz, C., Schmeda-Hirschmann, G. Article ISI SCOPUS FOOD SCIENCE NUTRITION (2016)
Antiproliferative activity and chemical composition of the venom from the Amazonian toad Rhinella marina (Anura: Bufonidae) Schmeda-Hirschmann, Guillermo; Quispe, Cristina; Arana, Gabriel Vargas; Theoduloz, Cristina; Urra, F?lix A.; C?rdenas, C?sar Article ISI SCOPUS TOXICON (2016)
Biological activities of polyphenols-enriched propolis from Argentina arid regions. Salas, A., Alberto, M.R., Zampini, C., Cuello, S., Maldonado, L., Rios, J.L., Isla, M.I., Schmeda-Hirschmann, G. Article PHYTOMEDICINE (2016)
Chemical profiling and antioxidant activity of Bolivian propolis Nina, N; Quispe, C; Jimenez-Aspee, F; Theoduloz, C; Gimenez, A; Schmeda-Hirschmann, G Article WOS ex (ISI). JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2016)
Fast high resolution Orbitrap MS fingerprinting of the resin of H. taltalense Phil. from the Atacama Desert. Simirgiotis, M.J., Quispe, C., Bórquez, J., Schmeda-Hirschmann, G., Avendaño, M., Sepúlveda, B., Winterhalter, P. Article INDUSTRIAL CROPS AND PRODUCTS (2016)
Flour from Prosopis alba cotyledons: A natural source of nutrient and bioactive phytochemicals Cattaneo F.; Costamagna M.S.; Zampini, I.C.; Sayago, J; Alberto, M.R.; Chamorro V.; Pazos, A.; Thomas-Valdés S.; Schmeda-Hirschmann, G; Isla, M.I. Article ISI SCOPUS FOOD CHEMISTRY (2016)
Fruit characteristics and cuticle triterpenes as related to postharvest quality of highbush blueberries Moggia, Claudia; Graell, Jordi; Lara, Isabel; Schmeda-Hirschmann, Guillermo; Thomas-Vald?s, Samanta; Lobos, Gustavo A. Article ISI SCOPUS SCIENTIA HORTICULTURAE (2016)
New homoisoflavanes, a new alkaloid and spirostane steroids from the roots of Herreria montevidensis Klotzsch ex Griseb. (Herreriaceae). Dutra-Behrens, M., Schmeda-Hirschmann, G. Article MOLECULES (2016)
Phenolics from the Patagonian currants Ribes spp.: isolation, characterization and cytoprotective effect in AGS cells. Jiménez-Aspee, F., Theoduloz, C., Vieira, M.N., Rodriguez-Werner, M.A., Schmalfuss, E., Winterhalter, P., Schmeda-Hirschmann, G. Article WOS (ex ISI) JOURNAL OF FUNCTIONAL FOODS (2016)
Polyphenol rich fraction from Geoffroea decorticans fruits flour affects key enzymes involved in metabolic syndrome, oxidative stress and inflammatory process. Costamagna, M.S., Zampini, I.C., Alberto, M.R., Cuello, S., Torres, S., Perez, J., Quispe, C., Schmeda-Hirschmann, G., Isla, M.I. (2016). Food Chemistry 190, 392-402. Article FOOD CHEMISTRY (2016)
The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells Jimenez-Aspee, F; Theoduloz, C; Avila, F; Thomas-Valdes, S; Mardones, C; von Baer, D; Schmeda-Hirschmann, G Article WOS (ex ISI) FOOD CHEMISTRY (2016)
Anti-inflammatory activity of Copao (Eulychnia acida Phil., Cactaceae) fruits. Jimenez-Aspee, F., Alberto, M.R., Quispe, C., Soriano, M. del P.C., Theoduloz, C., Isla, M.I., Schmeda-Hirschmann, G. Article PLANT FOODS FOR HUMAN NUTRITION (2015)
Antibacterial activity, antioxidant effect and chemical composition of propolis from Región del Maule, central Chile. Nina, V., Quispe, C., Jimenez-Aspee, F., Theoduloz, C., Leiva, E., Feresin, G.E., Lima, B., Schmeda-Hirschmann, G. Article MOLECULES (2015)
Chilean Prosopis mesocarp flour: phenolic profiling and antioxidant activity. Schmeda-Hirschmann, G, Quispe, C., Soriano, M.del P.C., Theoduloz, C., Jiménez-Aspee, F., Pérez, M.J., Cuello, A.S., Isla, M.I. Article MOLECULES (2015)
Efficacy of quercetin against chemically induced murine oral squamous cell carcinoma. Droguett D., Castillo C., Leiva E., Theoduloz C., Schmeda-Hirschmann G., Kemmerling U. Article ONCOLOGY LETTERS (2015)
Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway. Bueno, C.A., Michelini, F.M., Pertino, M.W., Gomez, C.A., Schmeda-Hirschmann, G., Alché, L. Article MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2015)
Phenolic profiling of the South American “Baylahuen” tea (Haplopappus spp., Asteraceae) by HPLC-DAD-ESI-MS. Schmeda-Hirschmann, G., Quispe, C., González, B. Article MOLECULES (2015)
Phytophthora austrocedri elicitates changes in diterpene profile of Austrocedrus chilensis. Olate, V.R., Vélez, M.L., Greslebin, A., Schmeda-Hirschmann, G. (2015). Molecules 20, 15084-15097. Article MOLECULES (2015)
Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic acid and carnosol derivatives. Pertino, M.W., Theoduloz, C., Butassi, E., Zacchino, S., Schmeda-Hirschmann, G. Article MOLECULES (2015)
Topical anti-inflammatory activity of new hybrid molecules of terpenes and synthetic drugs. Theoduloz, C., Delporte, C., Valenzuela-Barra, G., Silva, X., Cádiz, S., Bustamante, F., Pertino, M.W., Schmeda-Hirschmann, G. Article MOLECULES (2015)
Anti-inflammatory activity of animal oils from the Peruvian Amazon. Schmeda-Hirschmann, G., Delporte, C., Valenzuela-Barra, G., Silva, X., Vargas A., G., Lima, B. Feresin, G.E. Article JOURNAL OF ETHNOPHARMACOLOGY (2014)
Antioxidant activity and characterization of constituents in copao fruits (Eulychnia acida Phil., Cactaceae) by HPLC-DAD-MS/MSn Jimenez-Aspee, F; Quispe C.; Soriano, MDPC; Gonzalez, JF; Haneke, E; Theoduloz, C; Schmeda-Hirschmann G. Article FOOD RESEARCH INTERNATIONAL (2014)
Antioxidant activity and characterization of constituents in Copao fruits (Eulychnia acida Phil., Cactaceae) by HPLC-DAD-MS/MSn. Jiménez-Aspee F., Quispe C., Soriano M.D.P.C., Fuentes G., J., Hüneke, E., Theoduloz, C., Schmeda-Hirschmann G. Article FOOD RESEARCH INTERNATIONAL (2014)
Antioxidant effect and characterization of South American Prosopis pods syrup. Quispe, C., Petroll, K., Theoduloz, C., Schmeda-Hirschmann, G. Article Food Research International (2014)
Antioxidant effect and characterization of South American Prosopis pods syrup. Quispe, C., Petroll, K., Theoduloz, C., Schmeda-Hirschmann, G. Article FOOD RESEARCH INTERNATIONAL (2014)
Antiproliferative activity and new argininyl bufadienolide esters from the “Cururú” toad Rhinella (Bufo) schneideri. Schmeda-Hirschmann, G., Quispe, C., Theoduloz, C., Teixeira de Sousa, P., Parizotto, C. Article JOURNAL OF ETHNOPHARMACOLOGY (2014)
Gastroprotective mechanisms of action of semisynthetic carnosic acid derivatives in human cells Theoduloz, C., Pertino, M.W., Schmeda-Hirschmann, G. Article MOLECULES (2014)
Gastroprotective mechanisms of action of semisynthetic carnosic acid derivatives in human cells. Theoduloz, C., Pertino, M.W., Schmeda-Hirschmann, G. (2014). Molecules 19, 581-594. Article MOLECULES (2014)
Lemon Grass (Cymbopogon citratus (D.C) Stapf) polyphenols protect human umbilical vein endothelial cell (HUVECs) from oxidative damage induced by high glucose, hydrogen peroxide and oxidized low-density lipoprotein. Campos, J., Schmeda-Hirschmann, G., Leiva, E., Guzmán, L., Orrego, R., Fernández, P., González, M., Radojkovic, C., Zuñiga, F.A., Lamperti, L., Pastene, E., Aguayo, C. Article FOOD CHEMISTRY (2014)
Polyphenolic compounds and anthocyanin content of Prosopis nigra and Prosopis alba pods flour and their antioxidant and anti-inflammatory capacity. Pérez, M.J., Cuello, A.S., Zampini, I.C., Ordoñez, R.M., Alberto, M.R., Quispe, C., Schmeda-Hirschmann, G., Isla, M.I. Article FOOD RESEARCH INTERNATIONAL (2014)
Seasonal Variation and Resin Composition in the Andean Tree Austrocedrus chilensis Olate, VR; Soto, A; Schmeda-Hirschmann G. Article Molecules (2014)
Seasonal variation and resin composition in the Andean tree Austrocedrus chilensis. Olate, V.R., Soto, A., Schmeda-Hirschmann, G. Article MOLECULES (2014)
Synthesis and antiproliferative activity of some novel triazole derivatives from dehydroabietic acid. Pertino, M.W., Verdugo, V., Theoduloz, C., Schmeda-Hirschmann, G. Article MOLECULES (2014)
Synthesis and antiproliferative activity of some novel triazole derivatives from dehydroabietic acid. Pertino, M.W., Verdugo, V., Theoduloz, C., Schmeda-Hirschmann, G. (2014). Molecules 19, 2523-2535. Article MOLECULES (2014)
1,2,3-Triazole-Substituted Oleanolic Acid Derivatives: Synthesis and Antiproliferative Activity Pertino, MW; Lopez, C; Theoduloz, C; Schmeda-Hirschmann G. Article Molecules (2013)
1,2,3-triazole-substituted oleanolic acid derivatives: synthesis and antiproliferative activity. Pertino, M.W., Lopez, C., Theoduloz, C., Schmeda-Hirschmann, G. Article ISI MOLECULES (2013)
Antioxidant capacity, polyphenolic content and tandem HPLC-DAD-ESI/MS profiling of phenolic compounds from the South American berries Luma apiculata and L. chequen Simirgiotis, MJ; Borquez J.; Schmeda-Hirschmann G. Article Food Chemistry (2013)
Antioxidant capacity, polyphenolic content and tandem HPLC-DAD-ESI/MS profiling of phenolic compounds from the South American berries Luma apiculata and Luma chequén. Simirgiotis, M.J., Bórquez, J., Schmeda-Hirschmann, G. Article ISI FOOD CHEMISTRY (2013)
Bioactive coumarins and HPLC-PDA-ESI-ToF-MS metabolic profiling of edible queule fruits (Gomortega keule), an endangered endemic Chilean species Simirgiotis, MJ; Ramirez, JE; Hirschmann, GS; Kennelly, EJ Article ISI SCOPUS Food Research International (2013)
Dimeric Labdane Diterpenes: Synthesis and Antiproliferative Effects Pertino, MW; Theoduloz, C; Bastias, M; Schmeda-Hirschmann, G Article ISI SCOPUS MOLECULES (2013)
Diterpenylquinone Hybrids: Synthesis and Assessment of Gastroprotective Mechanisms of Action in Human Cells Theoduloz, C; Bravo, I; Pertino, MW; Schmeda-Hirschmann, G Article ISI SCOPUS MOLECULES (2013)
Gastroprotective mechanisms of action of semisynthetic carnosic acid derivatives in human cells. Theoduloz, C., Pertino, M.W., Schmeda-Hirschmann, G. Article MOLECULES (2013)
HIGH SPEED CENTRIFUGAL COUNTERCURRENT CHROMATOGRAPHY (HSCCC) ISOLATION AND IDENTIFICATION BY LC-MSn ANALYSIS OF THE POLAR PHENOLICS FROM VASCONCELLEA QUERCIFOLIA Quispe, Cristina; Viveros Valdez, Ezequiel; YARLEQUE, JOSÉ A; ARONES, MARCO R; PANIAGUA, JUAN C; Schmeda-Hirschmann, Guillermo Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2013)
In vivo antimalarial activity of Keetia leucantha twigs extracts and in vitro antiplasmodial effect of their constituents Bero, J; Herent, MF; Schmeda-Hirschmann, G; Frederich, M; Quetin-Leclercq, J Article ISI SCOPUS Journal of Ethnopharmacology (2013)
Inhibition of arachidonic acid metabolism by the Andean crude drug Parastrephia lucida (Meyen) Cabrera D'Almeida, RE; Isla, MI; Vildoza, EDL; Quispe, C; Schmeda-Hirschmann, G; Alberto, MR Article ISI SCOPUS Journal of Ethnopharmacology (2013)
The Passiflora tripartita (banana passion) fruit: a source of bioactive flavonoid C-glycosides isolated by HSCCC and characterized by HPLC–DAD–ESI/MS/MS. Simirgiotis, M., Schmeda-Hirschmann, G., Borquez, J., Kennelly. E. Article MOLECULES (2013)
Antimicrobial phenylpropanoids from the Argentinean highland plant Parastrephia lucida (Meyen) Cabrera Dalmeida R.E.; Alberto, M.R.; Quispe, C; Schmeda-Hirschmann, G; Isla, M.I. Article ISI SCOPUS Journal of Ethnopharmacology (2012)
Direct characterisation of phenolic antioxidants in infusions from four Mapuche medicinal plants by liquid chromatography with diode array detection (HPLC-DAD) and electrospray ionisation tandem mass spectrometry (HPLC-ESI-MS) Simirgiotis M.J.; Silva M.; Becerra J.; Schmeda-Hirschmann G. Article Food Chemistry (2012)
Direct characterization of phenolic antioxidants in infusions from four medicinal Mapuche plants by liquid chromatography with diode array detection (HPLC-DAD) and electrospray ionization tandem mass spectrometry (HPLC-ESI-MS). Simirgiotis, M.J., Silva, M., Becerra, J., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2012)
New gastroprotective labdeneamides from (4S,9R,10R) methyl 18-carboxi-labda-8,13(E)-diene-15-oate. Olate, V.R., Pertino, M.W., Theoduloz, C., Yesilada, E., Monsalve, F., González, P., Droguett, D., Richomme, P., Hadi, A.H.A., Schmeda-Hirschmann, G. Article PLANTA MEDICA (2012)
New gastroprotective labdeneamides from (4S,9R,10R) methyl 18-carboxy-labda-8,13(E)-diene-15-oate. Olate, Verónica Rachel; Pertino, Mariano Walter; Theoduloz, Cristina; Yesilada, Erdem; Monsalve, Francisco; González, Paulo; Droguett, Daniel; Richomme, Pascal; Hadi, A Hamid; Schmeda-Hirschmann, Guillermo Article Planta medica (2012)
Phenolic Constituents of the Chilean Herbal Tea Fabiana imbricata R. et P. Quispe, C; Viveros-Valdez, E; Schmeda-Hirschmann, G Article ISI SCOPUS Plant Foods for Human Nutrition (2012)
Potential Gastroprotective Effect of Novel Cyperenoic Acid/Quinone Derivatives in Human Cell Cultures Theoduloz, C; Carrion I.; Pertino, M; Valenzuela, D; Schmeda-Hirschmann, G Article ISI SCOPUS Planta Medica (2012)
VCD absolute configuration and complete 1H NMR characterization of rosmaridiphenol diacetate. Muñoz, M.A., Perez-Hernandez, N., Pertino, M.W., Schmeda-Hirschmann, G., Joseph-Nathan, P. Article Journal of Natural Products (2012)
VCD absolute configuration and complete 1H NMR characterization of rosmaridiphenol diacetate. Muñoz, M.A., Perez-Hernandez, N., Pertino, M.W., Schmeda-Hirschmann, G., Joseph-Nathan, P. Article JOURNAL OF NATURAL PRODUCTS (2012)
Anti-inflammatory, antinociceptive, and antipyretic effects of methanol extract of Cariniana rubra stem bark in animal models. Santos, E.N., Lima, J.C.S., Noldin, V.F., Cechinel-Filho, V., Rao, V.S.N., Lima, E.F., Schmeda-Hirschmann, G., de Sousa Jr., P.T., Martins, D.T.O. Article SCOPUS Anais da Academia Brasileira de Ciencias (2011)
Antiplatelet, anticoagulant, and fibrinolytic activity in vitro of extracts from selected fruits and vegetables Torres-Urrutia C.; Guzman, L; Schmeda-Hirschmann, G; Moore-Carrasco, R; Alarcon M.; Astudillo, L; Gutiérrez M; Carrasco, G; Yuri, JA.; Aranda, E; Palomo I. Article ISI SCOPUS Blood Coagulation and Fibrinolysis (2011)
Diterpenes from the resin of Austrocedrus chilensis. A GC-MS and 1HNMR analysis. Olate, V.R., Goikoetxeaundia, O., Schmeda-Hirschmann, G. Article MOLECULES (2011)
Gastroprotective Effect and Cytotoxicity of Carnosic Acid Derivatives Theoduloz, C; Pertino, M; Rodriguez JA.; Schmeda-Hirschmann, G Article ISI SCOPUS Planta Medica (2011)
Gastroprotective Effect and Cytotoxicity of Labdeneamides with Amino Acids Schmeda-Hirschmann, G; Rodríguez, J. A.; Theoduloz, C; Valderrama, J.A. Article ISI SCOPUS Planta Medica (2011)
Resin diterpenes from Austrocedrus chilensis. Olate, Verónica Rachel; Usandizaga, Olatz Goikoetxeaundia; Schmeda-Hirschmann, Guillermo Article Molecules (Basel, Switzerland) (2011)
Synthesis and Pharmacological Activity of Diterpenylnaphthoquinone Derivatives Pertino, MW; Theoduloz, C; Palenzuela, JA; Afonso, MD; Yesilada, E; Monsalve, F; Gonzalez P.; Droguett, D.; Schmeda-Hirschmann, G Article ISI SCOPUS MOLECULES (2011)
Argentinean Propolis from Zuccagnia punctata Cav. (Caesalpinieae) Exudates: Phytochemical Characterization and Antifungal Activity Aguero, MB; Gonzalez, M.; Lima B.; Svetaz L.; Sánchez, M; Zacchino, S; Feresin, GE; Schmeda-Hirschmann, G; Palermo, J; Wunderlin, D; Tapia, A Article ISI SCOPUS Journal of Agricultural and Food Chemistry (2010)
Determination of phenolic composition and antioxidant activity in fruits, rhizomes and leaves of the white strawberry (Fragaria chiloensis spp chiloensis form chiloensis) using HPLC-DAD-electrospray tandem mass spectrometry and free radical quenching techniques. Simirgiotis, M.J., Schmeda-Hirschmann, G. Article JOURNAL OF FOOD COMPOSITION AND ANALYSIS (2010)
Determination of phenolic composition and antioxidant activity in fruits, rhizomes and leaves of the white strawberry (Fragaria chiloensis spp. chiloensis form chiloensis) using HPLC-DAD-ESI-MS and free radical quenching techniques Simirgiotis, MJ; Schmeda-Hirschmann G. Article JOURNAL OF FOOD COMPOSITION AND ANALYSIS (2010)
Direct identification of phenolic constituents in Boldo Folium (Peumus boldus Mol.) infusions by high-performance liquid chromatography with diode array detection (HPLC-DAD) and electrospray ionization tandem mass spectrometry (HPLC-MSn). Simirgiotis, M.J., Schmeda-Hirschmann, G. Article JOURNAL OF CHROMATOGRAPHY A (2010)
Direct identification of phenolic constituents in Boldo Folium (Peumus boldus Mol.) infusions by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry Simirgiotis, MJ; Schmeda-Hirschmann G. Article JOURNAL OF CHROMATOGRAPHY A (2010)
Gastroprotective Effect of Carnosic Acid gamma-Lactone Derivatives Pertino, MW; Theoduloz, C; Rodriguez, JA; Yanez, T; Lazo, V; Schmeda-Hirschmann G. Article JOURNAL OF NATURAL PRODUCTS (2010)
Gastroprotective effect of carnosic acid γ-lactone derivatives. Pertino, M., Rodríguez, J.A., Theoduloz, C., Yáñez, T., Lazo, V., Schmeda-Hirschmann, G. Article JOURNAL OF NATURAL PRODUCTS (2010)
Synthesis, Gastroprotective Effect and Cytotoxicity of New Amino Acid Diterpene Monoamides and Diamides Schmeda-Hirschmann, G; Pertino, MW; Rodriguez JA.; Monsalve, F; Droguett, D.; Theoduloz, C Article ISI SCOPUS MOLECULES (2010)
The Corrected Structure of Rosmaridiphenol, a Bioactive Diterpene from Rosmarinus officinalis Pertino, MW; Schmeda-Hirschmann G. Article PLANTA MEDICA (2010)
The corrected structure of rosmaridiphenol, a bioactive diterpene from Rosmarinus officinalis L. Pertino, M.W., Schmeda-Hirschmann, G. Article PLANTA MEDICA (2010)
Antimicrobial activity of extracts, essential oil and metabolites obtained from Tagetes mendocina Lima, B., Aguero, MB., Zygadlo, J., Tapia, A., Solis, C., M., Rojas de Arias, A., Yaluff, G., Zacchino, S., Feresin, G.E., Schmeda-Hirschmann, G. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2009)
Antimicrobial and antioxidant compound from the infusion and polar extract of Baccharis incarum (Wedd.) Perkins. Zampini, I.C., Isla, M.I., Schmeda-Hirschmann, G. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2009)
ANTIMICROBIAL AND ANTIOXIDANT COMPOUNDS FROM THE INFUSION AND METHANOLIC EXTRACT OF Baccharis incarum (WEDD.) PERKINS Zampini, IC; Isla, MI; Schmeda-Hirschmann G. Article Journal of the Chilean Chemical Society (2009)
Antiproliferative activity of the diterpenes jatrophone and jatropholone and their derivatives. Theoduloz, Cristina; Rodríguez, Jaime A; Pertino, Mariano; Schmeda-Hirschmann, Guillermo Article Planta medica (2009)
Antiproliferative activity of the diterpenes jatrophone and jatropholone and their derivatives. Theoduloz, C., Rodríguez, J.A., Pertino, M., Schmeda-Hirschmann, G. Article PLANTA MEDICA (2009)
Comparison of phenolic composition and antioxidant properties of two native Chilean and one domestic strawberry genotypes. Simirgiotis, M.J., Theoduloz, C., Caligari, P.D.S., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2009)
Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean lamiaceae Sphacele chamaedryodes (Balbis) Briq. Areche, C., Schmeda-Hirschmann, G., Theoduloz, C., Rodríguez, J.A. Article Journal of Pharmacy and Pharmacology (2009)
Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean Lamiaceae Sphacele chamaedryoides (Balbis) Briq. Areche, Carlos; Schmeda-Hirschmann, Guillermo; Theoduloz, Cristina; Rodríguez, Jaime A Article The Journal of pharmacy and pharmacology (2009)
Identification of phenolic compounds from the fruits of the mountain papaya Vasconcellea pubescens A. DC grown in Chile by liquid chromatography-uv detection–mass spectrometry. Simirgiotis, M.J., Caligari, P.D.S., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2009)
Main flavonoids, DPPH activity and metal content allow determining the geographical origin of propolis from the Province of San Juan (Argentina). Lima, B., Tapia, A., Luna, L., Fabani, M.P., Schmeda-Hirschmann, G., Podio, N.S., Wunderlin, D.A., Feresin, G.E. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Main Flavonoids, DPPH Activity, and Metal Content Allow Determination of the Geographical Origin of Propolis from the Province of San Juan (Argentina) Lima, B; Tapia, A; Luna, L; Fabani, MP; Schmeda-Hirschmann G.; Podio, NS; Wunderlin, DA; Feresin, GE Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Transcript profiling suggests transcriptional repression of the flavonoid pathway in the white-fruited Chilean strawberry, Fragaria chiloensis (L.) Mill. Saud, G; Carbone, F; Perrotta, G; Figueroa, CR; Moya, M; Herrera R.; Retamales, JB; Carrasco, B; Cheel, J; Schmeda-Hirschmann G.; Caligari, PDS Article GENETIC RESOURCES AND CROP EVOLUTION (2009)
Transcript profiling suggests transcriptional repression of the flavonoid pathway in the white-fruited Chilean strawberry, Fragaria chiloensis (L.) Mill. Saud, G., Carbone, F., Perrotta, G., Figueroa, C.R., Moya, M., Herrera, R., Retamales, J.B., Carrasco, B., Cheel, J., Schmeda-Hirschmann, G., D. S. Caligari, P.D.S. Article GENETIC RESOURCES AND CROP EVOLUTION (2009)
A new antifungal and antiprotozoal depside from the Andean lichen Protousnea poepigii. Schmeda-Hirschmann, G., Tapia, A., Lima, B., Pertino, M., Sortino, M., Zacchino, S., Rojas de Arias, A., Feresin, G.E. Article PHYTOTHERAPY RESEARCH (2008)
Cycloaspeptide A and pseurotin A from the endophytic fungus Penicillium janczewskii Schmeda-Hirschmann, G., Hormazabal, E., Rodríguez, J., Theoduloz, C. Article Zeitschrift für Naturforschung (2008)
Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells. Bispo de Jesus, M., Zambuzzi, W.F., Ruela de Sousa, R.R., Areche, C., Santos de Souza, A.C., Aoyama, H., Schmeda-Hirschmann, G., Rodríguez, J.A., de Souza Brito, A.R.M., Peppelenbosch, M.P., den Hertog, J., de Paula, E., Ferreira, C.V. Article Biochimie (2008)
Free radical scavengers from the Mexican herbal tea “poleo” (Hedeoma drummondii). Viveros-Valdez, E., Rivas-Morales, C., Carranza-Rosales, P., Mendoza, S., Schmeda-Hirschmann, G. Article Zeitschrift für Naturforschung C (2008)
Free radical scavengers from the Mexican herbal tea “poleo” (Hedeoma drummondii). Viveros-Valdez, E., Rivas-Morales, C., Carranza-Rosales, P., Mendoza, S., Schmeda-Hirschmann, G. Article Zeitschrift für Naturforschung (2008)
Gastroprotective activity of ferruginol in mice and rats: effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls. Areche, C., Theoduloz, C., Yañez, T., Souza-Brito, A.R.M., Barbastefano, V., de Paula, D., Ferreira, A.L., Schmeda-Hirschmann, G., Rodríguez, J.A. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2008)
New gastroprotective ferruginol derivatives with selective cytotoxicity against gastric cancer cells. Espinoza, M; Santos, LS ; Theoduloz, C ; Schmeda-Hirschmann, G; Rodriguez, JA. Article Planta Medica (2008)
Studies on quinones. Part 43: synthesis and cytotoxic avaluation of polyoxyethylene-containing 1,4-naphthoquinones Valderrama, J.A., Leiva, H., Rodriguez, J.A., Theoduloz, C., Schmeda-Hirschmann, G. Article BIOORGANIC AND MEDICINAL CHEMISTRY (2008)
Biotransformation of jatrophone by Aspergillus niger ATCC 16404 Pertino, M; Schmeda-Hirschmann G.; Santos, LS; Rodriguez, JA; Theoduloz, C Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES (2007)
Biotransformation of jatrophone by Aspergillus niger ATCC 16404. Pertino, M., Schmeda-Hirschmann, G., Santos, L.S., Rodriguez, J., Theoduloz, C. Article Zeitschrift für Naturforschung (2007)
Biotransformations of imbricatolic acid by Aspergillus niger and Rhizopus nigricans cultures. Schmeda-Hirschmann, G., Aranda, C., Kurina, M., Rodríguez, J., Theoduloz, C. Article MOLECULES (2007)
Free radical scavengers from Cymbopogon citratus (DC.) stapf plants cultivated in bioreactors by the temporary immersion (TIS) principle Tapia, A; Cheel, J; Theoduloz, C; Rodriguez J.; Schmeda-Hirschmann G.; Gerth, A; Wilken, D; Jordan, M; Jimenez-Gonzalez, E; Gomez-Kosky, R; Mendoza, EQ Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2007)
Free radical scavenging activity and phenolic content in achenes and thalamus from Fragaria chiloensis ssp chiloensis, F vesca and F. x ananassa cv. Chandler Cheel, J; Theoduloz, C; Rodriguez, JA; Caligari, PDS; Schmeda-Hirschmann G. Article Food Chemistry (2007)
Free radical scavenging activity and phenolic content in achenes and thalamus from Fragaria chiloensis ssp. chiloensis, F. vesca and F. x ananassa cv. Chandler. Cheel, J., Theoduloz, C., Rodriguez, J., Caligari, P., Schmeda-Hirschmann, G. Article ISI FOOD CHEMISTRY (2007)
Free radical scavenging activity and secondary metabolites from in vitro cultures of Sanicula graveolens Cheel, J; Schmeda-Hirschmann G.; Jordan, M; Theoduloz, C; Rodriguez, JA; Gerth, A; Wilken, D Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2007)
Free radical scavenging activity and secondary metabolites from in vitro cultures of Sanicula graveolens. Cheel, J., Schmeda-Hirschmann, G., Jordan, M., Gerth, A., Wilken, D. Article Zeitschrift für Naturforschung (2007)
Gastroprotective and cytotoxic effect of semisynthetic ferruginol derivatives. Areche, C., Rodríguez, J.A., Razmilic, I., Yañez, T., Theoduloz, C., Schmeda-Hirschmann, G. Article Pharmacy and Pharmacology (2007)
Gastroprotective effect and cytotoxicity of diterpenes from the Paraguayan crude drug “yagua rova” (Jatropha isabelii). Pertino M., Schmeda-Hirschmann G., Rodríguez J., Theoduloz C. Article JOURNAL OF ETHNOPHARMACOLOGY (2007)
Gastroprotective effect and cytotoxicity of labdenamides. Izquierdo, R., Astudillo, L., Rodríguez, J.A., Theoduloz C., Palenzuela, J. A., Schmeda-Hirschmann G. Article PLANTA MEDICA (2007)
Gastroprotective effect and cytotoxicity of semisynthetic jatropholone derivatives. Pertino M., Schmeda-Hirschmann G., Rodríguez J., Theoduloz C. Article PLANTA MEDICA (2007)
Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug yagua rova" (Jatropha isabelli)" Pertino, M; Schmeda-Hirschmann G.; Rodriguez, JA; Theoduloz, C Article JOURNAL OF ETHNOPHARMACOLOGY (2007)
4-Methyl-1-hepten-3-one, the defensive compound from Agathemera elegans (Philippi) (Phasmatidae), Insecta SCHMEDA-HIRSCHMANN, G. Article Zeitschrift für Naturforschung (2006)
Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives Pertino, M; Rodriguez, JA; Theoduloz, C; Razmilic, I; Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models. Rodríguez, J., Theoduloz, C., Yáñez, T., Becerra, J., Schmeda-Hirschmann, G Article ISI LIFE SCIENCES (2006)
Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: In vitro-in vivo relationships Sanchez, M; Theoduloz, C; Schmeda-Hitschmann, G; Razmilic, I; Yanez, T; Rodriguez, JA Article LIFE SCIENCES (2006)
Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships. Sanchez, M., Theoduloz, C., Schmeda-Hirschmann, G., Razmilic, I., Yañez, T., Rodriguez, J. Article LIFE SCIENCES (2006)
Gastroprotective effect and cytotoxicity of cyperenoic acid derivatives. Pertino M., Rodríguez J., Theoduloz C., Razmilic I., Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Studies on Quinones. Part 40. Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products. Valderrama J, Espinoza O, Gonzalez F, Tapia R, Rodríguez JA, Theoduloz C, Schmeda-Hirschmann G. Article TETRAHEDRON (2006)
Studies on quinones. Part 40: Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products Valderrama, JA; Espinoza O.; Gonzalez, MF; Tapia, RA; Rodriguez, JA; Theoduloz, C; Schmeda-Hirschmann G. Article TETRAHEDRON (2006)
Studies on quinones. Part 41: Synthesis and cytotoxicity of isoquinoline-containing polycyclic quinones Valderrama, JA; Gonzalez, MF; Pessoa-Mahana D.; Tapia, RA; Fillion, H; Pautet, F; Rodriguez, JA; Theoduloz, C; Schmeda-Hirschmann G. Article BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Synthesis and cytotoxic activity of isoquinoline-containing polycyclic quinones. Valderrama, J.A., González, M.F., Pessoa-Mahana, D., Tapia, R.A., Fillion, H., Pautet, F., Rodríguez, J.A., Theoduloz, C., Schmeda-Hirschmann, G. Article BIOORGANIC AND MEDICINAL CHEMISTRY (2006)
Antimicrobial butyrolactone I derivatives from the ecuadorian soil fungus Aspergillus terreus thorn. Var terreus Cazar, ME; Schmeda-Hirschmann, G; Astudillo, L Article ISI SCOPUS WORLD JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY (2005)
Bioactive metabolites from the fungus Nectria galligena, the main apple canker agent in Chile Gutiérrez M; Theoduloz, C; Rodriguez J.; Lolas M.; Schmeda-Hirschmann, G Article ISI SCOPUS JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
E-cinnamic acid derivatives and phenolics from Chilean strawberry fruits, Fragaria chiloensis ssp chiloensis Cheel J.; Theoduloz, C; Rodriguez J.; Saud, G; Caligari, PDS; Schmeda-Hirschmann, G Article ISI SCOPUS JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
Free radical scavengers and antioxidants from Cymbopogon citratus (DC.) Stapf. Cheel, J., Theoduloz, C., Rodríguez, J., Schmeda-Hirschmann, G. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
Gastroprotective activity of a new semi-synthetic solidagenone derivative in mice Rodriguez, JA; Theoduloz, C; Sanchez, M; Yanez, T; Razmilic, W; Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2005)
Gastroprotective activity of a new semi-synthetic solidagenone derivative in mice. Rodríguez, J.A., Theoduloz, C., Sanchez, M., Yáñez T., Razmilic I., Schmeda-Hirschmann, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2005)
Gastroprotective activity of sesquiterpene derivatives from Fabiana imbricata Reyes, M; Schmeda-Hirschmann, G; Razmilic I.; Theoduloz, C; Yanez, T; Rodriguez JA. Article ISI SCOPUS PHYTOTHERAPY RESEARCH (2005)
Gastroprotective and cytotoxic effect of dehydroabietic acid derivatives Sepúlveda B.; Astudillo, L; Rodriguez JA.; Yanez, T; Theoduloz, C; Schmeda-Hirschmann, G Article ISI SCOPUS PHARMACOLOGICAL RESEARCH (2005)
Gastroprotective and ulcer-healing effect of new solidagenone derivatives in human cell cultures Rodriguez JA.; Theoduloz, C; Sánchez, M; Razmilic I.; Schmeda-Hirschmann, G Article ISI SCOPUS LIFE SCIENCES (2005)
Gastroprotective effect and cytotoxicity of natural and semisynthetic labdane diterpenes from Araucaria araucana resin Schmeda-Hirschmann G.; Astudillo, L; Sepulveda B.; Rodriguez, JA; Theoduloz, C; Yanez, T; Palenzuela, JA Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2005)
Gastroprotective effect and cytotoxicity of natural and semisynthetic labdane diterpenes from Araucaria araucana. Schmeda-Hirschmann, G., Astudillo S., L.., Sepúlveda V., B., Rodríguez C. J., Theoduloz, C., Yáñez T., Palenzuela, J.A. Article Zeitschrift für Naturforschung (2005)
Gastroprotective effect of the Mapuche crude drug Araucaria araucana resin and its main constituents Schmeda-Hirschmann, G; Astudillo, L; Rodriguez J.; Theoduloz, C; Yanez, T Article ISI SCOPUS JOURNAL OF ETHNOPHARMACOLOGY (2005)
Metabolites from Microsphaeropsis olivacea (Bonord.) Hohn, an endophytic fungus of Pilgerodendron uviferum (D. Don) Florin. Hormazabal, E., Schmeda-Hirschmann, G., Astudillo, L., Rodríguez, J., Theoduloz, C. Article Zeitschrift für Naturforschung (2005)
Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum Hormazabal, E; Schmeda-Hirschmann G.; Astudillo, L; Rodriguez J.; Theoduloz, C Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2005)
Proximate composition and free radical scavenging activity of edible fruits from the Argentinian Yungas Schmeda-Hirschmann, G; Feresin, G; Tapia, A; Hilgert, N; Theoduloz, C Article ISI SCOPUS JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2005)
Secondary metabolite content in rhizomes, callus cultures and in vitro regenerated plantlets of Solidago chilensis Schmeda-Hirschmann G.; Jordan, M; Gerth, A; Wilken, D Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2005)
Secondary metabolite content in rhizomes, cell, callus cultures and in vitro regenerated plantlets of Solidago chilensis. Schmeda-Hirschmann, G., Jordan, M., Gerth, A., Wilken, D. Article Zeitschrift für Naturforschung (2005)
Secondary metabolites from endophytic fungi isolated from the Chilean gimnosperm Prumnopitys andina (Lleuque) Schmeda-Hirschmann, G., Hormazabal, E., Astudillo, L., Rodriguez, J., Theoduloz, C. Article World Journal of Microbiology and Biotechnology (2005)
Secondary metabolites from endophytic fungi isolated from the Chilean gymnosperm Prumnopitys andina (Lleuque) Schmeda-Hirschmann G.; Hormazabal, E; Astudillo, L; Rodriguez J.; Theoduloz, C Article WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2005)
Synthesis of tricyclic analogs of stephaoxocanidine and their evaluation as acetylcholinesterase inhibitors Bianchi, DA; Hirschmann, GS; Theoduloz, C; Bracca, ABJ; Kaufman, TS Article ISI SCOPUS BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2005)
Traditional medicine and gastroprotective crude drugs. Schmeda-Hirschmann, G., Yesilada, E. Article JOURNAL OF ETHNOPHARMACOLOGY (2005)
1 beta,7 beta-Dihydroxydehydroabietic acid, a new biotransformation product of dehydroabietic acid by Aspergillus niger Gouiric, SC; Feresin, GE; Tapia, AA; Rossomando, PC; Schmeda-Hirschmann G.; Bustos, DA Article WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2004)
1,7-Dihydroxydehydroabietic acid, a new biotransformation product of dehydroabietic acid by Aspergillus niger. Gouiric, S.C., Feresin, G.E., Tapia, A A., Rossomando, P. C., Schmeda-Hirschmann, G., Bustos, D. A.. Article World Journal of Microbiology and Biotechnology (2004)
Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi Svetaz, L; Tapia, A; Lopez, SN; Furlan, RLE; Petenatti, E; Pioli, R; Schmeda-Hirschmann G.; Zacchino, SA Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi. Svetaz, L., Tapia, A., López, S.N., Furlán, R.L.E., Petenatti, E., Pioli, R., Schmeda-Hirschmann, G., Zacchino, S.A. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Bioguided isolation and identification of the non-volatile antioxidant compounds from fennel (Foeniculum vulgare Mill.) waste. Parejo, I., Viladomat, F., Bastida, J., Schmeda-Hirschmann, G., Burillo, J., Codina, C. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Bioguided isolation and identification of the nonvolatile antioxidant compounds from fennel (Foeniculum vulgare Mill.) waste Parejo, I; Viladomat, F; Bastida, J; Schmeda-Hirschmann G.; Burillo, J; Codina, C Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Biotransformation of solidagenone by Alternaria alternata, Aspergillus niger and Curvularia lunata cultures Schmeda-Hirschmann G.; Astudillo, L; Palenzuela, JA Article WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2004)
Biotransformation of Solidagenone by Alternaria alternata, Aspergillus niger and Curvularia lunata cultures. Schmeda-Hirschmann, G., Astudillo S., L., Palenzuela, J.A. Article World Journal of Microbiology and Biotechnology (2004)
Free radical scavengers and antioxidants from Baccharis grisebachii. Tapia, A., Rodriguez, J., Theoduloz, C., Lopez, S., Egly Feresin, G., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2004)
Free radical scavengers and antioxidants from Baccharis grisebachii Tapia, A; Rodriguez J.; Theoduloz, C; Lopez, S; Feresin, GE; Schmeda-Hirschmann G. Article JOURNAL OF ETHNOPHARMACOLOGY (2004)
Free radical scavengers and antioxidants from Tagetes mendocina Schmeda-Hirschmann G.; Tapia, A; Theoduloz, C; Rodriguez J.; Lopez, S; Feresin, GE Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2004)
Free radical scavengers and antioxidants from Tagetes mendocina. Schmeda-Hirschmann G., Tapia A., Theoduloz, C., Rodriguez, J, A., Lopez, S., Egly Feresin, G. Article Zeitschrift für Naturforschung (2004)
Secondary metabolite content in Fabiana imbricata plants and in vitro cultures Schmeda-Hirschmann G.; Jordan, M; Gerth, A; Wilken, D; Hormazabal, E; Tapia, AA Article ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES (2004)
Secondary metabolite content in Fabiana imbricata plants and in vitro cultures. Schmeda-Hirschmann, G., Jordan, M., Gerth, A., Wilken, D., Hormazabal, E., Tapia, A.A. Article Zeitschrift für Naturforschung (2004)
Antimicrobial activity of the Argentinian medicinal plant Baccharis grisebachii (Asteraceae). Feresin, G.E., Tapia, A., Gimenez, A, Gutierrez Ravelo, A., Zacchino, S., Sortino, M., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2003)
Bioactive alkyl phenols and embelin from Oxalis erythrorhiza Feresin, GE; Tapia, A; Sortino, M; Zacchino, S; De Arias, AR; Inchausti, A; Yaluff, G; Rodriguez J.; Theoduloz, C; Schmeda-Hirschmann G. Article JOURNAL OF ETHNOPHARMACOLOGY (2003)
Bioactive alkyl phenols and embelin from Oxalis erythrorhiza. Feresin, G.E., Tapia, A., Sortino, M., Zacchino, S., Rojas de Arias, A., Inchausti, A., Yaluff, G., Rodriguez C., J., Theoduloz, C., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2003)
Constituents of the Argentinian medicinal plant Baccharis grisebachii and their antimicrobial activity Feresin, GE; Tapia, A; Gimenez, A; Ravelo, AG; Zacchino, S; Sortino, M; Schmeda-Hirschmann G. Article JOURNAL OF ETHNOPHARMACOLOGY (2003)
Free radical scavengers and antioxidants from Peumus boldus Mol. (“Boldo”). Schmeda-Hirschmann, G., Rodriguez, J., Theoduloz, C., Astudillo, S.L., Feresin, G.E., Article FREE RADICAL RESEARCH (2003)
Naphtoquinone derivatives and lignans from the Paraguayan crude drug "Tayï pytá" (Tabebuia heptaphylla). Schmeda Hirschmann, G., Papastergiou, F. Article ISI Zeitschrift für Naturforschung (2003)
Oleanolic acid promotes healing of acetic acid-induced chronic gastric ulcers in rats. Rodríguez, J.A., Astudillo, L., Schmeda-Hirschmann, G. Article PHARMACOLOGICAL RESEARCH (2003)
Free radical scavengers, anti-inflammatory and analgesic activity of Acaena magellanica Feresin, GE; Tapia, A; Gutierrez A.; Delporte, C; Erazo, NB; Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2002)
Free radical scavengers, antiinflammatory and analgesic activity of Acaena magellanica. Feresin, G. E., Tapia, A., Gutierrez R., A., Delporte, C., Backhouse E., N., Schmeda-Hirschmann, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2002)
Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in mice. Astudillo, L., Rodríguez, J.A., Schmeda-Hirschmann, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2002)
Gastroprotective activity of solidagenone on experimentally induced gastric lesions in rats. Rodríguez, J.A., Bustamante C., Astudillo, L., Schmeda-Hirschmann, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2002)
Gastroprotective activity of the diterpene solidagenone and its derivatives on experimentally induced gastric lesions in mice Schmeda-Hirschmann G.; Rodriguez J.; Astudillo, L Article JOURNAL OF ETHNOPHARMACOLOGY (2002)
Gastroprotective activity of the diterpene solidagenone and its derivatives on experimentally induced gastric lesions in mice. Schmeda-Hirschmann, G., Rodríguez, J.A., Astudillo, L. Article JOURNAL OF ETHNOPHARMACOLOGY (2002)
Saponins from Cariniana rubra (Lecythidaceae). Lima, E., de Sousa Filho, P. T., Bastida, J., Schmeda-Hirschmann, G. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2002)
Alkaline substances used with coca (Erythroxylum coca Lam., Erythroxylaceae) leaf insalivation in northwestern Argentina. Hilgert, N., Reyes, S., Schmeda-Hirschmann, G. Article ECONOMIC BOTANY (2001)
Cryptofolione derivatives from Cryptocarya alba. Schmeda-Hirschmann, G., Astudillo, L., Bastida, J., Codina, C., Rojas de Arias, A., Ferreira, M.E., Inchaustti, A., Yaluff, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2001)
Immunomodulatory activity of Chilean Cyttaria species in mice with L5178Y lymphoma Schmeda-Hirschmann G.; Villasenor-Garcia, MM; Lozoya, X; Puebla-Perez, AM Article JOURNAL OF ETHNOPHARMACOLOGY (2001)
Immunomodulatory activity of Chilean Cyttaria species in mice with L5178Y lymphoma. Schmeda-Hirschmann, G., Puebla-Pérez, A.M., Villaseñor-García, M.M., Lozoya, X. Article JOURNAL OF ETHNOPHARMACOLOGY (2001)
Inhibitory activity of xanthine-oxidase and superoxide scavenger properties of Inga verna subsp. affinis. Its morphological and micrographic characteristics Vivot, E., Muñoz, J., Cruañes, M., Tapia, A., Martinez, E., Schmeda-Hirschmann, G., Zacchino, S. Article JOURNAL OF ETHNOPHARMACOLOGY (2001)
A DNA binding compound from Prosopis tamarugo pods. Schmeda-Hirschmann, G., Jakupovic, J. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2000)
A DNA BINDING COMPOUND FROM PROSOPIS TAMARUGO PODS Schmeda-Hirschmann G.; Jakupovic, J Article Boletín de la Sociedad Chilena de Química (2000)
Acetophenone derivatives from a Chilean isolate of Trichoderma longibrachiatum. Astudillo, L., Schmeda-Hirschmann, G., Soto, R., Sandoval, C., Afonso, C., Kijjoa, A. Article World Journal of Microbiology and Biotechnology (2000)
Acetophenone derivatives from Chilean isolate of Trichoderma pseudokoningii Rifai Astudillo, L; Schmeda-Hirschmann G.; Soto, R; Sandoval, C; Afonso, C; Gonzalez, MJ; Kijjoa, A Article WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2000)
Activity of Amaryllidaceae alkaloids on the blood pressure of normotensive rats. Schmeda-Hirschmann, G., Rodriguez, J. A., Loyola, J. I., Astudillo, L., Bastida, J., Viladomat, F., Codina, C. Article ISI JOURNAL OF PHARMACY AND PHARMACOLOGY (2000)
Activity of Solidagenone and their semisynthetic derivatives on the glucocorticoid-mediated signal transduction. Razmilic B., I., Schmeda-Hirschmann, G. Article PLANTA MEDICA (2000)
Biologically active alkaloids and a free radical scavenger from Prosopis species Tapia, A; Feresin, GE; Bustos, D; Astudillo, L; Theoduloz, C; Schmeda-Hirschmann G. Article JOURNAL OF ETHNOPHARMACOLOGY (2000)
Biologically active alkaloids and a free radical scavenger from Prosopis species. Tapia, A., Feresin, G.E., Bustos, D., Astudillo, L., Theoduloz, C., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2000)
BIOLOGICALLY ACTIVE COMPOUNDS FROM CHILEAN PROPOLIS Astudillo, L; Avila, F; Morrison, R; Gutierrez, M; Bastida, J; Codina, C; Schmeda-Hirschmann G. Article Boletín de la Sociedad Chilena de Química (2000)
Biologically active compounds from Chilean propolis. Astudillo, L., Avila, F., Morrison, R., Gutierrez C., M., Bastida, J., Codina, C., Schmeda-Hirschmann, G. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2000)
DNA binding activity of Amaryllidaceae alkaloids Schmeda-Hirschmann G.; Astudillo, L; Bastida, J; Viladomat, F; Codina, C Article Boletín de la Sociedad Chilena de Química (2000)
DNA binding activity of Amaryllidaceae alkaloids. Schmeda-Hirschmann, G., Astudillo, L., Bastida, J., Viladomat, F., Codina, C. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2000)
Free radical scavenging activity of Lafoensia pacari Solon, S; Lopes, L; De Sousa, PT; Schmeda-Hirschmann G. Article JOURNAL OF ETHNOPHARMACOLOGY (2000)
Free radical scavenging activity of Lafoensia pacari. Solon, S., Lopes, L., Teixeira de Sousa Jr., P., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2000)
Proximate composition and biological activity of Chilean Prosopis species Astudillo, L; Schmeda-Hirschmann G.; Herrera, JP; Cortes M. Article JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2000)
Proximate composition and biological activity of Chilean Prosopis species. Astudillo, L., Schmeda-Hirschmann, G., Herrera, J. P., Cortés, M.. Article JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2000)
Schmeda-Hirschmann, G., Rodriguez, J. A., Loyola, J. I., Astudillo, L., Bastida, J., Viladomat, F., Codina, C. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2000)
Biological activity and food analysis of Cyttaria spp. (Discomycetes). Schmeda-Hirschmann, G., Razmilic, I., Reyes, S., Gutierrez, M. I., Loyola, J. I. Article ECONOMIC BOTANY (1999)
DNA BINDING ALKALOIDS FROM LOBELIA BRIDGESII HOOK ET ARN AND LOBELIA TUPA L Marambio O.; Monsalve E.; Schmeda-Hirschmann G. Article Boletín de la Sociedad Chilena de Química (1999)
DNA binding alkaloids from Lobelia bridgesii Hook et Arn.and Lobelia tupa L. Marambio, O., Monsalve, E., , Schmeda-Hirschmann, G. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (1999)
DNA binding alkaloids from Prosopis alba. Astudillo, L., Jürgens, K., Schmeda-Hirschmann, G., Griffith, G.A., Holt, D.J., Jenkins, P.R. Article PLANTA MEDICA (1999)
Free radical scavengers from Mutisia friesiana (Asteraceae) and Sanicula graveolens (Apiaceae). Viturro, C., Molina, A., Schmeda-Hirschmann, G. Article PHYTOTHERAPY RESEARCH (1999)
Proximate composition and biological activity of food plants gathered by Chilean amerindians. Schmeda-Hirschmann, G., Razmilic, I., Gutierrez, M. I., Loyola, J. I. Article ECONOMIC BOTANY (1999)
Etnobotánica Ayoreo. Contribución al estudio de la flora y vegetación del Chaco. XI. Schmeda Hirschmann, G. Article Candollea (1998)
Antiprotozoal activity of Jatrogrossidione from Jatropha grossidentata and Jatrophone from Jatropha isabellii. Schmeda-Hirschmann, G., Razmilic, I., Sauvain, M., Moretti, C., Muñoz, V., Ruiz, E., Balanza, E., Fournet, A. Article PHYTOTHERAPY RESEARCH (1996)
Biological activity and xanthine oxidase inhibitors from Scirpus californicus (C. A. Mey.) Steud. Schmeda-Hirschmann, G., Gutiérrez, M. I., Loyola, J. I., Zúñiga, J. Article PHYTOTHERAPY RESEARCH (1996)
Secoisotetrandrine from Laurelia sempervirens. Schmeda Hirschmann, G., Dutra Behrens, M., Habermehl, G., Jakupovic, J. Article PHYTOCHEMISTRY (1996)
Xanthine oxidase inhibitory activity of flavonoids and tannins from Hexachlamys edulis (Myrtaceae). Schmeda-Hirschmann, G., Zúñiga, J., Dutra-Behrens, M., Habermehl, G. Article PHYTOTHERAPY RESEARCH (1996)
Biological activity of medicinal plants of Ica (Perú). Klinar, S., Castillo, P., Chang, A., Schmeda-Hirschmann, G., Reyes, S., Theoduloz, C., Razmilic, I. Article FITOTERAPIA (1995)
Effect of Fabiana imbricata constituents on Rhopalosiphum padi and Heliothis zea. Schmeda Hirschmann, G., Román, P., Theoduloz, C., Donoso, C., Corcuera, L. Article PHYTOTHERAPY RESEARCH (1995)
Flavonoids from Calycorectes, Campomanesia, Eugenia, and Hexachlamys species (Myrtaceae). Schmeda Hirschmann, G. Article FITOTERAPIA (1995)
Madia sativa, a potential oil crop of central Chile. Schmeda Hirschmann, G. Article ECONOMIC BOTANY (1995)
(24S) 3ß hydroxy ergost 5 en 6 one and other sterines from Cyttaria johowii Espinosa. Abraham, W. R., Schmeda Hirschmann, G. Article PHYTOCHEMISTRY (1994)
Hypoglycaemic activity of Geranium core core, Oxalis rosea and Plantago major extract in rats. Rodriguez, J., Loyola, J. I., Maulén, G., Schmeda Hirschmann, G. Article PHYTOTHERAPY RESEARCH (1994)
Hypotensive and diuretic effect of Equisetum bogotense and Fuchsia magellanica extract in rats and micropropagation of E. bogotense. Rodriguez, J., Pacheco, P., Razmilic, I., Loyola, J. I., Schmeda Hirschmann, G., Theoduloz, C. Article PHYTOTHERAPY RESEARCH (1994)
Hypotensive effect of Laurelia sempervirens (Monimiaceae) on normotensive rats. Schmeda Hirschmann, G., Loyola, J. I., Rodríguez, J., Dutra-Behrens, M. Article PHYTOTHERAPY RESEARCH (1994)
Plant resources used by the Ayoreo of the Paraguayan Chaco. Schmeda Hirschmann, G. Article ECONOMIC BOTANY (1994)
Rutin and scopoletin content and micropropagation of Fabiana imbricata. Razmilic, I., Schmeda Hirschmann, G., Dutra Behrens, M., Reyes, S., Lopez, I., Theoduloz, C. Article PLANTA MEDICA (1994)
Sesquiterpenes from Fabiana imbricata. Schmeda Hirschmann, G., Papastergiou, F. Article PHYTOCHEMISTRY (1994)
Tree ash as an Ayoreo salt source in the Paraguayan Chaco. Schmeda Hirschmann, G. Article ECONOMIC BOTANY (1994)
ß Glucuronidase inhibition and diuretic activity of Fabiana imbricata (Solanaceae). Schmeda Hirschmann, G., Loyola, J. I., Dutra Behrens, M., Reyes, S., Hubert, E., Rodríguez, M., Rodríguez, J. Article PHYTOTHERAPY RESEARCH (1994)
Antiviral activity of Chilean medicinal plant extracts. Pacheco, P., Sierra, J., Schmeda Hirschmann, G., Potter, C. W., Jones, B. M., Moshref, M.. Article PHYTOTHERAPY RESEARCH (1993)
Magic and medicinal plants of the Ayoreos of the Chaco Boreal (Paraguay). Schmeda Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (1993)
Prevalence of Chagas' disease in Ayoreo communities of the Paraguayan Chaco. Rojas de Arias, A., de Guillén, I., Inchausti, A., Samudio, M., Schmeda Hirschmann, G. Article Tropical Medicine and Parasitology (1993)
Two new 17 progesterone transformation products from Nocardia DSM 43298. Choudhry, S., Halos, S., Krischenowski, D., Schmeda Hirschmann, G. Article World Journal of Microbiology and Biotechnology (1993)
A screening method for natural products on Triatomine bugs Schmeda Hirschmann, G., Rojas de Arias, A. Article PHYTOTHERAPY RESEARCH (1992)
Diterpenes and a lignan from Jatropha grossidentata. Schmeda Hirschmann, G., Tsichritzis, F., Jakupovic, J. Article PHYTOCHEMISTRY (1992)
Feeding deterrency and insecticidal effects of plant extracts on Lutzomyia longipalpis. Rojas de Arias, A., Schmeda Hirschmann, G. Article PHYTOTHERAPY RESEARCH (1992)
Hypoglycaemic activity of Hexachlamys edulis ("Yvahai") extract in rats. Rodríguez, J., Loyola, J.I., Schmeda Hirschmann, G. Article PHYTOTHERAPY RESEARCH (1992)
Hypotensic effect and enzyme inhibitory activity of Mapuche medicinal plant extracts. Schmeda Hirschmann, G., Loyola, J. I., Sierra, J., Retamal, R., Rodriguez, J. Article PHYTOTHERAPY RESEARCH (1992)
Xanthine oxidase inhibitory activity of Chilean Myrtaceae. Theoduloz, C., Pacheco, P., Schmeda Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (1991)
A survey of medicinal plants of Minas Gerais, Brazil. Schmeda-Hirschmann, G., Rojas de Arias, A. Article JOURNAL OF ETHNOPHARMACOLOGY (1990)
Paraguayan medicinal Compositae. Schmeda Hirschmann, G., Bordas, E. Article JOURNAL OF ETHNOPHARMACOLOGY (1990)
Indigo from Eupatorium laeve. Schmeda Hirschmann, G., Ferro, E. Article JOURNAL OF ETHNOPHARMACOLOGY (1989)
A labdan diterpene from Solidago chilensis roots. Schmeda Hirschmann, G. Article PLANTA MEDICA (1988)
Ethnobotanical observations on Paraguayan Myrtaceae I. Schmeda Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (1988)
Eugenia uniflora leaf extract and lipid metabolism in Cebus apella monkeys. Ferro, E., Schinini, A., Maldonado, M., Rosner, J., Schmeda Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (1988)
Pyrrolizidine alkaloids from Senecio deferens. Schmeda Hirschmann, G., Jakupovic, J. Article PLANTA MEDICA (1988)
Rhamnofolane derivatives from Jatropha grossidentata. Jakupovic, J., Grenz, M., Schmeda Hirschmann, G. Article PHYTOCHEMISTRY (1988)
The effects of Melia azederach fruits on Triatoma infestans bugs. Rojas de Arias, A., Schmeda Hirschmann, G. Article FITOTERAPIA (1988)
Xanthine oxidase inhibitory activity of Paraguayan Myrtaceae. Theoduloz, C., Franco, L., Ferro, E., Schmeda Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (1988)
A magic use of Crotalaria incana pods. Schmeda Hirschmann, G., Franco, L., Ferro, E. Article JOURNAL OF ETHNOPHARMACOLOGY (1987)
Beyerene derivatives and other terpenoids from Stevia aristata. Zdero, C., Bohlmann, F., Schmeda Hirschmann, G. Article PHYTOCHEMISTRY (1987)
Further eudesmane derivatives from Verbesina species Jakupovic, J., Ellmauer, E., Jia, Y., Bohlmann, F., Domínguez, X. A., Schmeda Hirschmann, G. Article PLANTA MEDICA (1987)
Germacra 1, 10Z, 4E dien 12,8 a olides from Mikania micrantha. Boeker, R., Jakupovic, J., Bohlmann, F., Schmeda Hirschmann, G. Article PLANTA MEDICA (1987)
Preliminary pharmacological studies on Eugenia uniflora leaves: Xanthine oxidase inhibitory activity. Schmeda Hirschmann, G., Theoduloz, C., Franco, L., Ferro, E., Rojas de Arias, A. Article JOURNAL OF ETHNOPHARMACOLOGY (1987)
Pyrrolizidine alkaloid content in some Senecio grisebachii populations. Schmeda Hirschmann, G., Ferro, E., Céspedes, C., Recalde, L., Theoduloz, C. Article FITOTERAPIA (1987)
Pyrrolizidine alkaloids from Senecio brasiliensis populations. Schmeda Hirschmann, G., Ferro, E., Franco, L., Recalde, L., Theoduloz, C. Article JOURNAL OF NATURAL PRODUCTS (1987)
A myrtenylfuroheliangolide from Calea rupicola. Schmeda Hirschmann, G., Boeker, R., Jakupovic, J., Bohlmann, F. Article PHYTOCHEMISTRY (1986)
Balansolide and other sesquiterpene lactones from Bejaranoa balansae. Schmeda Hirschmann, G., Jakupovic, J., Pathak, V. P., Bohlmann, F. Article PHYTOCHEMISTRY (1986)
Dimeric guajanolide and other constituents from Gochnatia species. Bohlmann, F., Zdero, C., Schmeda Hirschmann, G., Jakupovic, J., Domínguez, X. A., King, R.M., Robinson, H. Article ISI PHYTOCHEMISTRY (1986)
Further sesquiterpenelactones from Elephantopus mollis and Centratherum punctatum. Banerjee, S., Schmeda Hirschmann, G., Castro, V., Schuster, A., Jakupovic, J., Bohlmann, F. Article PLANTA MEDICA (1986)
Hirsutinolide, glaucolide and new type of sesquiterpene lactones from Vernonia species. Jakupovic, J., Schmeda Hirschmann, G., Schuster, A., Zdero, C., Bohlmann, F., King, R. M., Robinson, H., Pickardt, J. Article ISI PHYTOCHEMISTRY (1986)
Melampolides and germacranolides from Stevia amambayensis. Schmeda Hirschmann, G., Zdero, C., Bohlmann, F. Article PHYTOCHEMISTRY (1986)
Retrorsin from a Paraguayan herbal tea. Schmeda Hirschmann, G., Céspedes, C. Article JOURNAL OF ETHNOPHARMACOLOGY (1986)
The constituents of Ambrosia tenuifolia and Pectis odorata. Schmeda Hirschmann, G., Bohlmann, F., Jakupovic, J. Article Revista Latinoamericana de Química (1986)
A new type of pyrrolizidine alkaloid from Senecio grisebachii Baker var. grisebachii. Schmeda Hirschmann, G., Banerjee, S., Jakupovic, J. Article Revista Latinoamericana de Química (1985)
Clerodane and labdane diterpenoids from Baccharis species. Bohlmann, F., Banerjee, S., Jakupovic, J., Grenz, M., Misra, L.N., Schmeda Hirschmann, G., King, R. M., Robinson, H. Article Identification of new diterpenes and other compounds from Baccharis species PHYTOCHEMISTRY (1985)
Eremophilane derivatives and other constituents from Senecio species. Bohlmann, F., Zdero, C., Jakupovic, J., Misra, L. N., Banerjee, S., Singh, P., Baruah, R. N., Metwally, M. A., Schmeda Hirschmann, G., Vincent, L. P. D., King, R. M., Robinson, H. Article PHYTOCHEMISTRY (1985)
Further sesquiterpene lactones from Calea and Viguiera species. Schmeda Hirschmann, G., Zdero, C., Baruah, R. N., Bohlmann, F. Article PHYTOCHEMISTRY (1985)
Isodaucane derivatives, norsesquiterpenes and clerodanes from Chromolaena laevigata. Misra, L. N., Jakupovic, J., Bohlmann, F., Schmeda Hirschmann, G. Article TETRAHEDRON (1985)
New vernolepin derivatives from Vernonia glabra and glaucolides from Vernonia scorpioides. Jakupovic, J., Baruah, R. N., Thi, T. V. S., Bohlmann, F., Msonthi, J. D., Schmeda Hirschmann, G. Article PLANTA MEDICA (1985)
Further 6, 12 cis germacranolides and eudesmanolides from Montanoa species. Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J., Castro, V., Ciccio, J.F., Calvo, G. Article JOURNAL OF NATURAL PRODUCTS (1984)
Germacranolides from Gochnatia vernonioides. Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J., King, R.M., Robinson, H. Article PHYTOCHEMISTRY (1984)
Heliangolide, Trachyloban und Villanovan Derivate aus Viguiera Arten. Bohlmann, F., Zdero, C., Schmeda Hirschmann, G., Jakupovic, J., Castro, V., King, R.M., Robinson, H. Article EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (1984)
Neue Melampolide aus Acanthospermum australe. Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J. Article PLANTA MEDICA (1984)
New chromolaenin derivatives from Chromolaena christieana. Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J., Ates (Gören), N., King, R.M., Robinson, H. Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (1984)
New heliangolides and germacranolides from Disynaphia multicrenulata. Bohlmann, F., Schmeda Hirschmann, G. , Jakupovic, J. Article PHYTOCHEMISTRY (1984)
Nor ent Labdan Derivate aus Austroeupatorium inulaefolium. Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J. Article PLANTA MEDICA (1984)
The constituents from Achyrocline satureioides D.C. Schmeda Hirschmann, G. Article Revista Latinoamericana de Química (1984)
Decathieleanolide, ein dimeres Guajanolid aus Decachaeta thieleana. Castro, V., Ciccio, F., Alvarado, S., Bohlmann, F., Schmeda Hirschmann, G., Jakupovic, J. Article EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (1983)
The flavonoids from Eupatorium laeve D.C. Schmeda, G., Pacheco, P., Silva, M. Article Identification of flavonoids by chromatography and UV spectroscopy. Revista Latinoamericana de Química (1983)
Arylated analogues of cypronazole: fungicidal efect and activity on human fibroblasts. Docking analysis and molecular dynamics simulations Herrera-Cano, N., Andujar, S.A., Theoduloz, C., Wunderlin, D.A., Santiago, A.N., Schmeda Hirschmann, G., Enriz, R.D., Feresin, G.E. Article Natural Products and Bioprospecting
Phenolics from the Patagonian currants Ribes spp.: Isolation, characterization and cytoprotective effect in human AGS cells Jimenez-Aspee, F; Theoduloz, C; Vieira, MN; Rodriguez-Werner, MA; Schmalfuss, E; Winterhalter, P; Schmeda-Hirschmann, G* (*corresponding autor) Article JOURNAL OF FUNCTIONAL FOODS


Chilean White Strawberry: Phenolic Profiling of its Different Parts Schmeda-Hirschmann, G., Viveros-Valdez, E., Montenegro, R., Quispe, C., Simirgiotis, M.; A.M. Husaini and D. Neri BookSection (2016)
Ethnopharmacology as a basis for medicinal chemistry studies: combining natural products and semisynthesis for gastroprotective agents Schmeda-Hirschmann, G., Theoduloz, C.; Mukherjee, P.K. BookSection (2014)
Chemistry of the Chilean strawberry (Fragaria chiloensis spp. chiloensis). Schmeda-Hirschmann, G., Simirgiotis, M., Cheel, J.; Amjad M. Husaini and José A. Mercado BookSection (2011)
.Comparison of secondary plant metabolite production in cell suspensions, callus culture and temporary immersion system. Wilken, D., Jiménez, E., Hohe, A., Jordan, M., Gomez Kosky, R., Schmeda-Hirschmann, G., Gerth, A.; Hvoslef-Eide, A.K.; Preil, W. BookSection (2005)
Bioactive products from South American plants. Schmeda Hirschmann, G.; Jonas, R., Pandey, A., Tharum, G. BookSection (2004)


Usos de especie de Cittaria (Diguenes), para estimular la respuesta inmune del organismo, procedimiento para preparar los extractos solubles de Cittaria Schmeda Hirschmann, G. Patent (2009)


A metabolomic approach on the health promoting effect of phenolics and saponins from Chilean beans and squash Schmeda-Hirschmann, Guillermo; THEODULOZ, CRISTINA; Avila, Felipe; Droguett, Daniel Proyecto (2021)
Cape Horn International Center for Global Change Studies and Biocultural Conservation (CHIC) Rozzi, Ricardo; Schmeda-Hirschmann, G Proyecto (2021)
Multidisciplinary studies on bioactive compounds from the Chilean Phaseolus vulgaris L. landraces and their potential effects in the prevention of non-communicable chronic diseases Carrasco, Basilio Alejandro; Schmeda-Hirschmann, G Proyecto (2021)
Espectrómetro de Resonancia Magnética Nuclear de 500 MHz para potenciar investigaciones interdisciplinarias en química orgánica, caracterización de compuestos bioactivos y metabolómica en Chile y la Región del Maule. FONDEQUIP (EQM170074) Proyecto 2018-2033 Inv. Responsable
Phenolic metabolome of Chilean native nuts and seeds: antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome Schmeda Hirschmann, G.; Theoduloz, C.; Avila, F.; Jimenez-Aspee, F. Proyecto (2017)
Phenolic metabolome of Chilean native nuts and seeds=> antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome FONDECYT (1170090) Proyecto 2017-2021 Inv. Responsable
LA BIODIVERSIDAD IBEROAMERICANA COMO FUENTE DE RECURSOS NATURALES PARA SU EXPLOTACION SOSTENIBLE (BIFRENES) CYTED (Red 416RT0511) Proyecto 2016-2019 Coinvestigador(a)
METABOLOMICS OF CHILEAN NATIVE FRUITS FONDECYT (1120096) Proyecto 2012-2016 Inv. Responsable
Metabolomics of Chilean native fruits Schmeda Hirschmann, G.; Theoduloz, C. Proyecto (2012)
Novel hybrid terpene-naphthoquinone gastroprotective compounds: synthesis and assessment of action mechanisms using human cell culture models Theoduloz, C.; SCHMEDA-HIRSCHMANN, G. Proyecto (2011)
NOVEL HYBRID TERPENE-NAPHTHOQUINONE GASTROPROTECTIVE COMPOUNDS=> SYNTHESIS AND ASSESSMENT OF ACTION MECHANISMS USING HUMAN CELL CULTURE MODELS. FONDECYT (1110054) Proyecto 2011-2015 Coinvestigador(a)
Semisynthesis of new gastroprotective labdane diterpenes: structure-activity relationships Schmeda Hirschmann, G.; Theoduloz, C.; Rodríguez, J. Proyecto (2008)
SEMISYNTHESIS OF NEW GASTROPROTECTIVE LABDANE DITERPENES=> STRUCTURE-ACTIVITY RELATIONSHIPS. FONDECYT (1085306) Proyecto 2008-2012 Inv. Responsable
Fortalecimiento innovativo de la investigación en productos bioactivos (FIPROBIO). Schmeda Hirschmann, G. Proyecto (2007)
Estudio del mecanismo gastroprotector de diterpenos naturales y hemisinteticos derivados del ferruginol y carnosol, utilizando modelos animales y cultivo de celulas epiteliales gastricas humanas Rodriguez, J.; Theoduloz, C.; SCHMEDA-HIRSCHMANN, G. Proyecto (2006)
ESTUDIO DEL MECANISMO GASTROPROTECTOR DE DITERPENOS NATURALES Y HEMISINTETICOS DERIVADOS DEL FERRUGINOL Y CARNOSOL, UTILIZANDO MODELOS ANIMALES Y CULTIVO DE CELULAS EPITELIALES GASTRICAS HUMANAS. FONDECYT (1060841) Proyecto 2006-2010 Coinvestigador(a)
ACTIVIDAD ANTIULCEROGENICA DE PRODUCTOS DE HEMISINTESIS Y BIOTRANSFORMACIONES DEL ACIDO ABIETICO, DEHIDROABIETICO Y ACIDO IMBRICATOLICO. FONDECYT (1030583) Proyecto 2003-2007 Inv. Responsable
Antioxidants, antifungic and antiparasitary compounds from Protousnea poepigii, Tagetes mendocina, Usnea florida and Zucccagnia punctata. Schmeda Hirschmann, G.; Rojas de Arias, A.; Zacchino, S.; Furlan,R. Proyecto (2003)
Antiulcerogenic activity of hemisynthesis and biotransformation products from abietic-, dehydroabietic- and imbricatolic acid. Schmeda Hirschmann, G.; Theoduloz, C.; Rodríguez, J. Proyecto (2003)
ESTUDIO DE LA ACTIVIDAD GASTROPROTECTORA DEL ACIDO OLEANOLICO, SOLIDAGENONA Y DERIVADOS DE HEMISINTESIS Y BIOTRANSFORMACIONES, UTILIZANDO MODELOS BASADOS EN EL CULTIVO DE CELULAS EPITELIALES GASTRICAS. FONDECYT (1030792) Proyecto 2003-2006 Coinvestigador(a)
Geographic variation in mistletoe seed dispersal in southern South America (Argentina & Chile). Aizen, M.; Amico, G.; Kenigsten, A.; SCHMEDA-HIRSCHMANN, G. Proyecto (2003)
Mechanism of the gastroprotective activity of oleanolic acid, solidagenone and their hemisynthesis and biotransformation products on epitelial gastric cells in culture. Rodriguez, J.; SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (2003)
Free radical scavengers and enzyme inhibitors from South American medicinal and aromatic plants Schmeda Hirschmann, G. Proyecto (2000)
Programa de Investigación en Productos Naturales Bioactivos Schmeda Hirschmann, G. Proyecto (2000)
Biotransformaciones de acido oleanolico y solidagenona y su actividad antiulcerogenica. Biotransformations of oleanolic acid and solidagenone and its antiulcerogenic activity FONDECYT (1990872) Proyecto 1999-2001 Inv. Responsable
Biotransformations of oleanolic acid and solidagenone and its antiulcerogenic activity Schmeda Hirschmann, G.; Rodríguez, J.; Theoduloz, C. Proyecto (1999)
Actividad biológica y química del género Prosopis en Argentina y Chile Schmeda Hirschmann, G. Proyecto (1998)
Adaptación de Azadirachta indica y Melia azederach (Meliaceae) al secano costero de la VII Región Schmeda Hirschmann, G.; Muñoz, M.; Astudillo, L. Proyecto (1997)
New trends and know-how transfer in the search for bioactive compounds Schmeda Hirschmann, G. Proyecto (1997)
Plantas alimenticias y medicinales de Amerindios chilenos=> química y actividad biológica. FONDECYT (1941165) Proyecto 1994-1996 Inv. Principal
Plantas alimenticias y medicinales de Amerindios chilenos: química y actividad biológica Schmeda Hirschmann, G.; Theoduloz, C. Proyecto (1994)
Antiviral and antiprotozoal compounds from South American crude drugs Schmeda Hirschmann, G. Proyecto (1992)
Metabolitos secundarios biológicamente activos de plantas Sudamericanas Schmeda Hirschmann, G. Proyecto (1992)
The active constituents of Hexachlamys edulis (Myrtaceae), an hypoglycaemiating South American crude drug Schmeda Hirschmann, G. Proyecto (1992)
Química, actividad biológica y micropropagación de plantas medicinales Mapuches. FONDEF (039/90) Proyecto 1990-1992 Inv. Responsable
Ayoreo ethnobotany Schmeda Hirschmann, G. Proyecto (1990)
Plant antivirals Schmeda Hirschmann, G. Proyecto (1990)
Química, actividad biológica y micropropagación de plantas medicinales Mapuches Schmeda Hirschmann, G.; Theoduloz, C. Proyecto (1990)
Química, actividad biológica y etnobotánica de las Mirtáceas de la VII Región, Maule Schmeda Hirschmann, G.; Theoduloz, C. Proyecto (1989)
Chemistry of Paraguayan medicinal Myrtaceae Schmeda Hirschmann, G. Proyecto (1988)
Natural Products as alternative in controlling Chagas' disease Schmeda Hirschmann, G.; Rojas de Arias, A. Proyecto (1987)
Natural Products as alternative in controlling Chagas' disease vectors Guillermo Schmeda Hirschmann; Antonieta Rojas de Aras Proyecto (1987)
Alexander von Humboldt Fellowship Schmeda Hirschmann, G. Proyecto (0)
Evaluación de Productos Naturales sobre Rhodnius neglectus y Tripanosoma cruzi, vector y causante de la enfermedad de Chagas Schmeda Hirschmann, G.; Rojas de Arias, A. Proyecto (0)


Bioactive Constituents from South American Prosopis and their Use and Toxicity Schmeda-Hirschmann G.; Theoduloz C.; JimÃ©nez-Aspee F.; EcheverrÃa J. Review ISI SCOPUS CURRENT PHARMACEUTICAL DESIGN (2020)

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Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

Samanta Thomas

Profesor Titular

Facultad de Farmacia

Universidad de Valparaíso

Valparaíso, Chile

Maria Theoduloz

Planta Profesional

UNIVERSIDAD DE TALCA

Talca, Chile

Cristina Quispe

ACADEMICO

FACULTAD DE CIENCIAS DE LA SALUD

UNIVERSIDAD ARTURO PRAT

IQUIQUE, Chile

margarita gutierrez

Proffesor

UNIVERSIDAD DE TALCA

Talca, Chile

Rodrigo Moore

Profesor Asociado

Bioquímica Clínica e Inmunohematología

UNIVERSIDAD DE TALCA

Talca, Chile

Marcelo Alarcón

Profesor

Bioquimica Clinica e Inmunahematologia

UNIVERSIDAD DE TALCA

Talca, Chile

Iván Palomo

Hematology Professor

Clinical Biochemistry and Immunohematology

UNIVERSIDAD DE TALCA

Talca, Chile

Felipe Avila

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

Alberto Burgos

Asistente de Investigación

Departamento de investigación

Universidad Nacional de Asunción

San Lorenzo, Paraguay

MARIANO PERTINO

Profesor conferenciante

UNIVERSIDAD DE TALCA, INSTITUTO DE QUÍMICA DE RECURSOS NATURALES

TALCA, Chile

Daniel Mieres

Postdoctorante

Instituto de Ciencias Biológicas

Universidad de Talca

Talca, Chile

Daniel Droguett

Profesor Conferenciante

Estomatología

Universidad de Talca

Talca, Chile

Gustavo Lobos

Associate Professor

Horticulture

FACULTDAD DE CIENCIAS AGRARIAS, UNIVERSIDAD DE TALCA

Talca, Chile

CLAUDIA MOGGIA

PROFESOR ASOCIADO

HORTICULTURA

UNIVERSITY OF TALCA

Talca, Chile

Jose Yuri

Profesor Titular y Director del Centro de Pomáceas

Producción Agrícola

UNIVERSIDAD DE TALCA

Talca, Chile

MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Ivanna Bravo

Docente

Instituto de Química de Recursos Naturales

Universidad de Talca

Talca, Chile

Luis Guzman

Profesor Asistente

Departamento Bioquímica Clínica e Inmunohematología

UNIVERSIDAD DE TALCA

Talca, Chile

MAURICIO LOLAS

Investigador

Producción Agrícola

Universidad de Talca

Talca, Chile

Javier Echeverría

Profesor Asistente e Investigador

Departamento de Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

Peter Caligari

Science Advisor

CGNA

Temuco, Chile

Jaime Valderrama

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Eduardo Aranda

Biochemist

Hematology

P. UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Gilda Carrasco

PROFESOR TITULAR

HORTICULTURA

UNIVERSIDAD DE TALCA

Talca, Chile

JEAN DE ANDRADE

Académico Docente

Departamento de Medicina Traslacional

Universidad Católica del Maule

Talca, Chile

Félix Urra

Profesor asistente

Facultad de Medicina, Instituto de Ciencias Biomédicas, Programa de Farmacología Molecular y Clínica

University of Chile

Santiago, Chile

Sebastián Fuentes

Investigador Postdoctoral

Institulo de Ciencias Biomédicas - Instituto de investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

Guillermo Schmeda Hirschmann

Líneas de Investigación

Educación

Bioquímico, Universidad Nacional de Asuncion, Paraguay. Paraguay, 1978

Organic Chemistry, TECHNISCHE UNIVERSITAT BERLIN. Alemania, 1984

Experiencia Académica

Profesor Investigador Full Time

Asesor Científico Part Time

Profesor Titular Full Time

Experiencia Profesional

Microbiólogo Full Time

Formación de Capital Humano

Premios y Distinciones

AvH Stipendium

Article (324)