Man

Felipe Avila

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

Líneas de Investigación


Productos de glicación avanzada y su asociación con estrés oxidativo y enfermedades crónicas; Mecanismos moleculares de protección frente a estrés oxidativo

Educación

  •  Licenciatura en Química, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2005
  •  Doctorado en Química, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010
  •  Químico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2006

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE TALCA

    Facultad de Ciencias de la Salud

    Talca, Chile

    2018 - 2022

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE TALCA

    Facultad de Ciencias de la Salud

    Talca, Chile

    2022 - A la fecha

Experiencia Profesional

  •   Jefe de Unidad de Análisis

    Centro de Nutrición molecular y Enfermedades Crónicas / Pontificia Universidad Católica de Chile

    Chile

    2010 - 2011

  •   Investigador Postdoctorado

    Université Pierre et Marie Curie - Paris VI

    Francia

    2011 - 2013


 

Article (28)

Effect of the Chilean Bean Landrace Peumo on Metabolic Syndrome-Related Parameters in C57BL/6 Mice Fed With a High-Fat Diet

Avila, Felipe; Droguett, Daniel.; Theoduloz, Cristina; Schmeda-Hirschmann, G

Article WOS
MOLECULAR NUTRITION AND FOOD RESEARCH  (2025)

Effect of Thermal Treatment on the Extraction and Antioxidant and Antiglycation Activities of (Poly)phenols from Ribes magellanicum

Avila, Felipe; Martinez, Natalia; Mora, Nicolas; Marquez, Katherine; Jimenez-Aspee, Felipe

Article ISI
MOLECULES  (2025)

Thermal treatment under oxidative conditions increases the antioxidant and antiglycation activity of Chilean Tortola beans ( Phaseolus vulgaris)

Basoalto-Cubillos, Aracely

Article ISI
FOOD CHEMISTRY  (2025)

Chilean papaya (Vasconcellea pubescens A. DC.) residues as a source of bioactive compounds: Chemical composition, antioxidant capacity, and antiglycation effects

Pino, Liudis L.; Farias, Dafne Reyes; Olivares-Caro, Lia; Mitsi, Christina; Mardones, Claudia; ECHEVERRIA-MORGADO, JAVIER FELIPE; Avila, Felipe; GUTIERREZ-CABRERA, MARGARITA ISABEL

Article SCOPUS
Heliyon  (2024)

Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces

Fuentealba, Denis; Vejar-Vivar, Carmina

Article ISI
JOURNAL OF FUNCTIONAL FOODS  (2022)

Modulation of 1,2-Dicarbonyl Compounds in Postprandial Responses Mediated by Food Bioactive Components and Mediterranean Diet



Article ISI
ANTIOXIDANTS  (2022)

Oleuropein-Enriched Extract From Olive Mill Leaves by Homogenizer-Assisted Extraction and Its Antioxidant and Antiglycating Activities

Pardo, Ximena

Article ISI
FRONTIERS IN NUTRITION  (2022)

Antiglycating Effect of Phenolics from the Chilean Currant Ribes cucullatum under Thermal Treatment



Article ISI
ANTIOXIDANTS  (2021)

Phenolic composition, antioxidant capacity and alpha-glucosidase inhibitory activity of raw and boiled Chilean Araucaria araucana kernels



Article ISI
FOOD CHEMISTRY  (2021)

Effect of advanced glycation end products on platelet activation and aggregation: a comparative study of the role of glyoxal and methylglyoxal



Article ISI
PLATELETS  (2020)

Vitamin C Recycling Regulates Neurite Growth in Neurospheres Differentiated In Vitro

Espinoza, Francisca; Saldivia, Natalia; Jara, Nery

Article ISI
ANTIOXIDANTS  (2020)

3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism

Silva, Eduardo

Article ISI SCOPUS
FREE RADICAL BIOLOGY AND MEDICINE  (2019)

Additive effect of maqui (Aristotelia chilensis) and lemon (Citrus x limon) juice in the postprandial glycemic responses after the intake of high glycemic index meals in healthy men

Gómez, Carla; González, Ma Angélica

Article SCOPUS
NFS Journal  (2019)

Andean Prumnopitys Andina (Podocarpacae) Fruit Extracts: Characterization of Secondary Metabolites and Potential Cytoprotective Effect

Theoduloz, Cristina; Pormetter, Lisa; Mettke, Judith

Article ISI SCOPUS
MOLECULES  (2019)

Avocado Oil: Characteristics, Properties, and Applications

Saravia, Carolina; Valdes, Hugo

Article ISI SCOPUS
MOLECULES  (2019)

Oxidation of myofibrillar proteins induced by peroxyl radicals: Role of oxidizable amino acids



Article ISI SCOPUS
FOOD RESEARCH INTERNATIONAL  (2019)

Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases

Fuentes, Eduardo

Article ISI SCOPUS
MOLECULES  (2019)

The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose



Article ISI SCOPUS
MOLECULES  (2018)

A Chilean Berry Concentrate Protects against Postprandial Oxidative Stress and Increases Plasma Antioxidant Activity in Healthy Humans

Pérez, Druso; Trejo, Sebastián

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2017)

Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells

Cristina Theoduloz,2; Eva Dorta; Guillermo Schmeda-Hirschmann

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2017)

Oxidative Modifications in Crystallin Proteins and Lens Epithelial Cells Associated with Photosensitized Reactions Mediated by the Major Chromophore Arising from Glucose Degradation

Vargas F.; Friguet, B; Silva, E.; Avila, F

Article ISI SCOPUS
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY  (2016)

The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells

Jiménez-Aspee, F; Theoduloz, C; Avila, F; Thomas Valdes, S.; Mardones, C.; von Baer D.; Schmeda-Hirschmann, G

Article ISI SCOPUS
FOOD CHEMISTRY  (2016)

Photosensitizing Activity of Endogenous Eye Lens Chromophores=> An Attempt to Unravel Their Contributions to Photo-Aging and Cataract Disease.

Avila, Felipe; Friguet, Bertrand

Article
PHOTOCHEMISTRY AND PHOTOBIOLOGY  (2015)

Serum Ferritin Is Associated with Metabolic Syndrome and Red Meat Consumption

Felipe, A; Guadalupe, E; Druso, P; Carlos, M; Pablo, S; Oscar, C; Luis, V; Diego M.; Jaime, R; Ines, U; et al.

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2015)

Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome

Avila, F; Trejo, S.; Friguet, B; Silva, E.

Article ISI SCOPUS
Biochimica et Biophysica Acta - Molecular Basis of Disease  (2012)

Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C

Avila, F; Friguet, B; Silva, E.

Article ISI SCOPUS
Photochemical and Photobiological Sciences  (2010)

Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration.

Avila, Felipe; Matus, Alex; Fuentealba, Denis; Lissi, Eduardo; Friguet, Bertrand; Silva, Eduardo

Article
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology  (2008)

Comparative chemical composition of the trichome secreted exudates and of the waxy coating from Haplopappus velutinus, H. illinitus, H. shumanni and H. uncinatus



Article ISI
BIOCHEMICAL SYSTEMATICS AND ECOLOGY  (2004)

Proyecto (7)

Polyphenols from Chilean native berries as antiglycating agents submitted to thermal treatment conditions: a contribution to decrease deleterious effects mediated by dietary glycotoxins

Theoduloz, Maria Cristina

Proyecto
 (2022)

A metabolomic approach on the health promoting effect of phenolics and saponins from Chilean native beans and squash



Proyecto
 (2020)

Phenolic metabolome of Chilean native nuts and seeds=> antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome

FONDECYT (1170090)

Proyecto
2017-2020
Coinvestigador(a)

Photosensitized reactions mediated by novel chromophores arising from degradation of carbohydrates=> Do they play an important role in eye lens photo-aging and cataract disease?

FONDECYT (11150657)

Proyecto
2015-2018
Inv. Responsable

Berries chilenos para el control de enfermedades crónicas

Fundación COPEC Universidad Católica (6C029)

Proyecto
2010-2011
Investigador(a)

I CONCURSO DE PROYECTOS DE ALIMENTOS FUNCIONALES - 2010 - AF10I1014 DISEÑO Y CARACTERIZACIÓN FUNCIONAL DE ADITIVOS ALIMENTARIOS SALUDABLES, RICOS EN ANTIOXIDANTES Y FIBRA, OBTENIDOS DE BAGAZO DE VITIS VINIFERA, PARA LA PREVENCIÓN DE ENFERMEDADES CRÓNICAS

FONDEF (AF10I1014)

Proyecto
2010-2013
Investigador(a)

EFECTO DE LAS REACCIONES DE GLICACION SOBRE LOS SISTEMAS PROTEICOS DE DEFENSA DE LENTE OCULAR=> UNA CONTRIBUCION AL ENTENDIMIENTO DEL ENVEJECIMIENTO DE ESTE TEJIDO Y A SU PREVENCION O RETRASO

FONDECYT (1050965)

Proyecto
2005-2009
Tesista

1
Iván Palomo

Hematology Professor

Clinical Biochemistry and Immunohematology

UNIVERSIDAD DE TALCA

Talca, Chile

1
Dietrich von Baer

Profesor Titular

Análisis Instrumental

UNIVERSIDAD DE CONCEPCIÓN - FACULTAD DE FARMACIA

Concepción, Chile

1
Claudia Mardones

Académica

Departamento Análisis Instrumental

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2
Camilo López

prof. Asociado

Química Física

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

1
Maria Theoduloz

Planta Profesional

UNIVERSIDAD DE TALCA

Talca, Chile

2
Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

1
Nora Lutz

Directora Departamento Salud Pública

Salud Pública

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

1
Veronica Olate

Profesional experto

Departamento de Bioquímica Clínica e Inmunohematología

Universidad de Talca

TALCA, Chile

2
Denis Fuentealba

PROFESOR ASOCIADO

QUIMICA FISICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Marcos Flores

academico

de Horticultura

Universidad de Talca

TALCA, Chile

1
Hugo Valdés

Académico

Ingeniería Computación e Informática

UNIVERSIDAD CATÓLICA DEL MAULE

Talca, Chile

1
Eduardo Fuentes

Profesor Titular

Universidad de Talca

Talca, Chile

30
Felipe Avila

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

1
claudia vergara

PROFESOR ASISTENTE

Ciencias Básicas

Universidad Santo Tomás

TALCA, Chile

1
FRANCISCO VARGAS

1
Guadalupe Echeverría

Manager

Center for Molecular Nutrition and Chronic Diseases

Pontificia Universidad Católica de Chile

Santiago, Chile

1
oscar castillo

Director Escuela

Facultad de Medicina

Universidad Finis Terrae

Santiago, Chile

1
Luciano Ferrada

Investigador

Biología celular

Universidad de Concepción

Concepcion, Chile

2
Ines Urquiaga

Coordinador Cientifico

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Samanta Thomas

Profesor Titular

Facultad de Farmacia

Universidad de Valparaíso

Valparaíso, Chile

4
Katherine Márquez

Académico

Ingeniería en Alimentos

Universidad del Bío-Bío

Chillán, Chile

1
Eduardo Fuentes

Profesor Asistente

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Marta Ravello

1
Nadia Cruz

1
Nery Jara

Profesor Asistente

Departamento de Farmacología

Universidad de Concepción

Concepción, Chile

1
maria angelica gonzalez bravo

academica

ciencia de la salud

Universidad de Talca

talca, Chile

1
ALEJANDRO VALLEJOS

Profesor Asistente

Ciencia y Tecnología de los Alimentos

Universidad de Concepción

Concepcion, Chile

1
Francisca Espinoza

Investigadora postdoctoral

Facultad de Medicina

Universidad Católica de la Santisima Concepción

Concepción, Chile

1
Javier Antileo

Secretario de Estudios

Universidad San Sebastián

Valdivia, Chile

1
Carmina Vejar