Man

Felipe Avila

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

Líneas de Investigación


Productos de glicación avanzada y su asociación con estrés oxidativo y enfermedades crónicas; Mecanismos moleculares de protección frente a estrés oxidativo

Educación

  •  Licenciatura en Química, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2005
  •  Doctorado en Química, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010
  •  Químico, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2006

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE TALCA

    Facultad de Ciencias de la Salud

    Talca, Chile

    2018 - 2022

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE TALCA

    Facultad de Ciencias de la Salud

    Talca, Chile

    2022 - A la fecha

Experiencia Profesional

  •   Jefe de Unidad de Análisis

    Centro de Nutrición molecular y Enfermedades Crónicas / Pontificia Universidad Católica de Chile

    Chile

    2010 - 2011

  •   Investigador Postdoctorado

    Université Pierre et Marie Curie - Paris VI

    Francia

    2011 - 2013


 

Article (24)

Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces

Avila, Felipe; Cruz, Nadia; Alarcon-Esposito, Jazmin; Nina, Nelida; Paillan, Hernan; Marquez, Katherine; Fuentealba, Denis; Burgos-Edwards, Alberto; Theoduloz, Cristina; Vejar-Vivar, Carmina; Schmeda-Hirschmann, Guillermo

Article ISI
JOURNAL OF FUNCTIONAL FOODS  (2022)

Modulation of 1,2-Dicarbonyl Compounds in Postprandial Responses Mediated by Food Bioactive Components and Mediterranean Diet

Cruz, Nadia; Flores, Marcos; Urquiaga, Ines; Avila, Felipe

Article ISI
ANTIOXIDANTS  (2022)

Oleuropein-Enriched Extract From Olive Mill Leaves by Homogenizer-Assisted Extraction and Its Antioxidant and Antiglycating Activities

Marquez, Katherine; Marquez, Nicole; avila, Felipe; Cruz, Nadia; Burgos-Edwards, Alberto; Pardo, Ximena; Carrasco, Basilio

Article ISI
FRONTIERS IN NUTRITION  (2022)

Antiglycating Effect of Phenolics from the Chilean Currant Ribes cucullatum under Thermal Treatment

Avila, Felipe; Ravello, Natalia; Manriquez, Camila; Jimenez-Aspee, Felipe; Schmeda-Hirschmann, Guillermo; Theoduloz, Cristina

Article ISI
ANTIOXIDANTS  (2021)

Phenolic composition, antioxidant capacity and alpha-glucosidase inhibitory activity of raw and boiled Chilean Araucaria araucana kernels

Schmeda-Hirschmann, Guillermo; Antileo-Laurie, Javier; Theoduloz, Cristina; Jimenez-Aspee, Felipe; Avila, Felipe; Burgos-Edwards, Alberto; Olate-Olave, Veronica

Article ISI
FOOD CHEMISTRY  (2021)

Effect of advanced glycation end products on platelet activation and aggregation: a comparative study of the role of glyoxal and methylglyoxal

Arriagada-Petersen, C.; Fernandez, P.; Gomez, M.; Ravello, N; Palomo, I.; Fuentes, E.; Ávila, F.

Article ISI
PLATELETS  (2020)

Vitamin C Recycling Regulates Neurite Growth in Neurospheres Differentiated In Vitro

Espinoza, Francisca; Magdalena, Rocio; Saldivia, Natalia; Jara, Nery; Martinez, Fernando; Ferrada, Luciano; Salazar, Katterine; Avila, Felipe; Nualart, Francisco

Article ISI
ANTIOXIDANTS  (2020)

3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism

Avila, Felipe; Ravello, Natalia; Zanocco, Antonio L.; Gamon, Luke F.; Davies, Michael J.; Silva, Eduardo

Article ISI SCOPUS
FREE RADICAL BIOLOGY AND MEDICINE  (2019)

Additive effect of maqui (Aristotelia chilensis) and lemon (Citrus x limon) juice in the postprandial glycemic responses after the intake of high glycemic index meals in healthy men

Ávila, Felipe; Jiménez-Aspee, Felipe; Cruz, Nadia; Gómez, Carla; González, Ma Angélica; Ravello, Natalia

Article SCOPUS
NFS Journal  (2019)

Andean Prumnopitys Andina (Podocarpacae) Fruit Extracts: Characterization of Secondary Metabolites and Potential Cytoprotective Effect

Jimenez-Aspee, Felipe; THEODULOZ, CRISTINA; Pormetter, Lisa; Mettke, Judith; Avila, Felipe; Schmeda-Hirschmann, Guillermo

Article ISI SCOPUS
MOLECULES  (2019)

Avocado Oil: Characteristics, Properties, and Applications

Flores, Marcos; Saravia, Carolina; Vergara, Claudia E.; Avila, Felipe; Valdes, Hugo; Ortiz-Viedma, Jaime

Article ISI SCOPUS
MOLECULES  (2019)

Oxidation of myofibrillar proteins induced by peroxyl radicals: Role of oxidizable amino acids

Dorta, E.; Avila, F.; Fuentes-Lemus, E.; Fuentealba, D.; Lopez-Alarcon, C.

Article ISI SCOPUS
FOOD RESEARCH INTERNATIONAL  (2019)

Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases

Lutz, Mariane; FUENTES, EDUARDO; Avila, Felipe; Alarcon, Marcelo; Palomo, Ivan

Article ISI SCOPUS
MOLECULES  (2019)

The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose

Avila, F; Schmeda-Hirschmann, G; Silva, E

Article ISI SCOPUS
MOLECULES  (2018)

A Chilean Berry Concentrate Protects against Postprandial Oxidative Stress and Increases Plasma Antioxidant Activity in Healthy Humans

Urquiaga, Inés; Ávila, Felipe; Echeverría, Guadalupe; Pérez, Druso; Trejo, Sebastián; Leighton, Federico

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2017)

Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells

Felipe Ávila; Cristina Theoduloz,2; Camilo López-Alarcón; Eva Dorta; Guillermo Schmeda-Hirschmann

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2017)

Oxidative Modifications in Crystallin Proteins and Lens Epithelial Cells Associated with Photosensitized Reactions Mediated by the Major Chromophore Arising from Glucose Degradation

Vargas F.; Becker, MI; Friguet, B; Silva, E.; Ávila F.

Article ISI SCOPUS
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY  (2016)

The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells

Jimenez-Aspee, F; Theoduloz, C; Ávila F.; Thomas-Valdes, S; Mardones, C.; von Baer, D.; Schmeda-Hirschmann, G

Article ISI SCOPUS
FOOD CHEMISTRY  (2016)

Photosensitizing Activity of Endogenous Eye Lens Chromophores=> An Attempt to Unravel Their Contributions to Photo-Aging and Cataract Disease.

Avila, Felipe; Friguet, Bertrand

Article
PHOTOCHEMISTRY AND PHOTOBIOLOGY  (2015)

Serum Ferritin Is Associated with Metabolic Syndrome and Red Meat Consumption

Felipe, A; Guadalupe, E; Druso, P; Carlos, M; Pablo S.; Oscar, C; Luis, V; Diego M.; Jaime, R; Ines, U; Federico, L

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2015)

Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome

Ávila F.; Trejo, S.; Baraibar M.A.; Friguet, B; Silva, E.

Article ISI SCOPUS
Biochimica et Biophysica Acta - Molecular Basis of Disease  (2012)

Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C

Ávila F.; Friguet, B; Silva, E.

Article ISI SCOPUS
Photochemical and Photobiological Sciences  (2010)

Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration.

Avila, Felipe; Matus, Alex; Fuentealba, Denis; Lissi, Eduardo; Friguet, Bertrand; Silva, Eduardo

Article
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology  (2008)

Comparative chemical composition of the trichome secreted exudates and of the waxy coating from Haplopappus velutinus, H. illinitus, H. shumanni and H. uncinatus

Urzua, A; Contreras, R; Jara, P; Avila, F; Suazo, M

Article ISI
BIOCHEMICAL SYSTEMATICS AND ECOLOGY  (2004)

Proyecto (7)

Polyphenols from Chilean native berries as antiglycating agents submitted to thermal treatment conditions: a contribution to decrease deleterious effects mediated by dietary glycotoxins

Avila, Felipe; López-Alarcón, Camilo; Theoduloz, Maria Cristina; Schmeda-Hirschmann, Guillermo

Proyecto
 (2022)

A metabolomic approach on the health promoting effect of phenolics and saponins from Chilean native beans and squash

Schemeda-Hirschman, Guillermo; THEODULOZ, CRISTINA; Avila, Felipe; Droguett, Daniel

Proyecto
 (2020)

Phenolic metabolome of Chilean native nuts and seeds=> antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome

FONDECYT (1170090)

Proyecto
2017-2020
Coinvestigador(a)

Photosensitized reactions mediated by novel chromophores arising from degradation of carbohydrates=> Do they play an important role in eye lens photo-aging and cataract disease?

FONDECYT (11150657)

Proyecto
2015-2018
Inv. Responsable

Berries chilenos para el control de enfermedades crónicas

Fundación COPEC Universidad Católica (6C029)

Proyecto
2010-2011
Investigador(a)

I CONCURSO DE PROYECTOS DE ALIMENTOS FUNCIONALES - 2010 - AF10I1014 DISEÑO Y CARACTERIZACIÓN FUNCIONAL DE ADITIVOS ALIMENTARIOS SALUDABLES, RICOS EN ANTIOXIDANTES Y FIBRA, OBTENIDOS DE BAGAZO DE VITIS VINIFERA, PARA LA PREVENCIÓN DE ENFERMEDADES CRÓNICAS

FONDEF (AF10I1014)

Proyecto
2010-2013
Investigador(a)

EFECTO DE LAS REACCIONES DE GLICACION SOBRE LOS SISTEMAS PROTEICOS DE DEFENSA DE LENTE OCULAR=> UNA CONTRIBUCION AL ENTENDIMIENTO DEL ENVEJECIMIENTO DE ESTE TEJIDO Y A SU PREVENCION O RETRASO

FONDECYT (1050965)

Proyecto
2005-2009
Tesista

26
Felipe Avila

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

3
Marta Ravello

2
Camilo López

prof. Asociado

Química Física

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Ines Urquiaga

Coordinador Cientifico

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Katherine Márquez

Researcher

Researcher

Centro de Estudios en Alimentos Procesados

Talca, Chile

2
Marcos Flores

academico

de Horticultura

Universidad de Talca

TALCA, Chile

2
Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

1
Denis Fuentealba

PROFESOR ASOCIADO

QUIMICA FISICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Luciano Ferrada

Investigador

Biología celular

Universidad de Concepción

Concepcion, Chile

1
Nery Jara

Profesor Asistente

Departamento de Farmacología

Universidad de Concepción

Concepción, Chile

1
Maria Theoduloz

Planta Profesional

UNIVERSIDAD DE TALCA

Talca, Chile

1
Hugo Valdés

Académico

Ingeniería Computación e Informática

UNIVERSIDAD CATÓLICA DEL MAULE

Talca, Chile

1
Samanta Thomas

Profesor Titular

Facultad de Farmacia

Universidad de Valparaíso

Valparaíso, Chile

1
Francisca Espinoza

Investigadora postdoctoral

Facultad de Medicina

Universidad Católica de la Santisima Concepción

Concepción, Chile

1
maria angelica gonzalez bravo

academica

ciencia de la salud

Universidad de Talca

talca, Chile

1
Veronica Olate

INVESTIGADOR ASISTENTE

Departamento de Investigaciones Interdisciplinarias

Universidad de Talca

TALCA, Chile

1
Nadia Cruz

1
Eduardo Fuentes

Profesor Asistente

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Javier Antileo

Secretario de Estudios

Universidad San Sebastián

Valdivia, Chile

1
Iván Palomo

Hematology Professor

Clinical Biochemistry and Immunohematology

UNIVERSIDAD DE TALCA

Talca, Chile

1
Eduardo Fuentes

Profesor Titular

Universidad de Talca

Talca, Chile

1
Nora Lutz

Directora Departamento Salud Pública

Salud Pública

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

1
Carmina Vejar

1
oscar castillo

Director Escuela

Facultad de Medicina

Universidad Finis Terrae

Santiago, Chile

1
Guadalupe Echeverría

Manager

Center for Molecular Nutrition and Chronic Diseases

Pontificia Universidad Católica de Chile

Santiago, Chile

1
FRANCISCO VARGAS

1
María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

1
Dietrich von Baer

Profesor Titular

Análisis Instrumental

UNIVERSIDAD DE CONCEPCIÓN - FACULTAD DE FARMACIA

Concepción, Chile

1
Claudia Mardones

Académica

Departamento Análisis Instrumental

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile