Man

Cinthya Ruiz-Tagle

Research Assistant

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Tuberculosis diagnosis, Tuberculosis biomarkers

Educación

  •  Bachelor in Bioengineering, UNIVERSIDAD DE CONCEPCION. Chile, 2008
  •  Bioengineering, UNIVERSIDAD DE CONCEPCION. Chile, 2009
  •  Master in Biochemistry and Bioinformatics, UNIVERSIDAD DE CONCEPCION. Chile, 2010
  •  PhD in Molecular Biosciences, UNIVERSIDAD ANDRES BELLO. Chile, 2016
  •  Biostatistics, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2021

Experiencia Académica

  •   Instructor Part Time

    UNIVERSIDAD ANDRES BELLO

    Faculty of Biological Sciences

    Santiago, Chile

    2011 - 2012

  •   Teaching assistant Part Time

    UNIVERSIDAD DE CONCEPCION

    Faculty of Biological Sciences

    Concepción, Chile

    2009 - 2009

Experiencia Profesional

  •   Research Assistant Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2017 - A la fecha

Premios y Distinciones

  •   National Doctoral Fellowship

    CONICYT

    Chile, 2010

    Scholarship to finance doctoral studies at Chilean universities.

  •   Scholarship to support the doctoral thesis

    CONICYT

    Chile, 2012

    Scholarship to finance the development of the doctoral thesis - CONICYT 24120956.

  •   Scholarship to support the doctoral thesis

    UNIVERSIDAD ANDRES BELLO

    Chile, 2012

    Scholarship to finance the development of the doctoral thesis - UNAB DI-72-12 / I.

  •   Exchange program (EULAMDIMA)

    EULAMDIMA

    Chile, 2014

    Scholarship to finance the internships of the Exchange program (EULAMDIMA) at the University of Heidelberg (Mannheim, Germany).


 

Article (7)

Humoral immune-response to a SARS-CoV-2-BNT162b2 booster in inflammatory arthritis patients who received an inactivated virus vaccine
Reduced immune response to inactivated SARS-CoV-2 vaccine in a cohort of immunocompromised patients in Chile
Vitamin D and cathelicidin levels and susceptibility to Mycobacterium tuberculosis infection acquisition in household contacts
Systematic screening of adult household contacts of patients with active pulmonary tuberculosis reveals high rates of new infections during follow-up
Unraveling the Role of MicroRNAs in Mycobacterium tuberculosis Infection and Disease: Advances and Pitfalls
Diagnostic performance of GM-CSF and IL-2 in response to long-term specific-antigen cell stimulation in patients with active and latent tuberculosis infection
Recruitment and subnuclear distribution of the regulatory machinery during 1 alpha,25-dihydroxy vitamin D-3-mediated transcriptional upregulation in osteoblasts

ConferencePoster (13)

Immune response to inactivated vaccine against SARS-CoV-2 in a cohort of immunocompromised patients in Chile.
Detection of antibodies against specific antigens of Mycobacterium tuberculosis in saliva samples in patients with active pulmonary tuberculosis, a pilot study
Active and prolonged screening reveals high number of secondary cases of tuberculosis in adult contacts
Antibody detection against Mycobacterium tuberculosis antigens in saliva from patients with active pulmonary tuberculosis
MiRNAs differential expression pattern distinguishes uninfected household contacts from those with newly acquired latent tuberculosis infection
Early tuberculosis infections assessed by serial QuantiFERON TB-Gold Plus testing in a prospective cohort of household contacts
Association of VDR with the nuclear matrix: Identification of specific domains
Domains in the Vitamin D receptor that mediate interactions with the nuclear matrix in osteoblasts
Developing methodologies to obtain soluble nuclear matrix protein components associated with vitamin D-mediated transcriptional response in osteoblasts
Differential contribution of p160/SRC and DRIP/TRAP co-activator complexes during vitamin D-dependent up-regulation of target genes in osteoblastic cell
Differential contribution of p160/SRC and DRIP/TRAP co-activator complexes during vitamin D-dependent up-regulation of target genes in osteoblastic cells
Optimization of methodologies for the production and analysis of the vitamin D receptor obtained by the baculovirus system
Recruitment and subnuclear distribution of the regulatory machinery during 1α,25-dihydroxyvitamin D3-mediated transcriptional activation in osteoblastic cells

Proyecto (5)

STRENGTHENING OF AIRBORNE PREVENTIVE MEASURES INSIDE HOUSEHOLDS OF PULMONARY TB CASES AS A TOOL TO REDUCE NEW INFECTIONS IN CLOSE CONTACTS. A PILOT, CONTROLLED, PRE-POST STUDY
EVALUATION OF THE IMMUNE RESPONSE TO THE INACTIVATED SARS-COV-2 VACCINE IN A COHORT OF ADULT PATIENTS WITH SEVERE ACQUIRED IMMUNOSUPPRESSION
DETERMINANTS FOR TUBERCULOSIS INFECTION ACQUISITION IN CONTACTS: EXPLORING THE ROLE OF NASOPHARYNGEAL MUCOSAL ENVIRONMENT
C/EBPBETA-MEDIATED CONTROL OF TRANSCRIPTION DURING OSTEOBLAST DIFFERENTIATION
MECHANISMS THAT CONTROL TRANSCRIPTIONAL RESPONSIVENESS TO 1a,25-DIHYDROXY VITAMIN D3 IN OSTEOBLASTS
25
Cinthya Ruiz-Tagle

Research Assistant

Department of Infectious Disease

Pontificia Universidad Católica de Chile

Santiago, Chile

2
María Balcells

Associate Professor

Department of Infectious Diseases of the Adult

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Rodrigo Naves

Associate Professor

Program of Immunology

Universidad de Chile

Santiago, Chile

1
Monique Le Corre

Assistant Professor

Faculty of medicine, Pediatric division

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Martín Montecino

Director

Institute of Biomedical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Berta Henriquez

Profesor Asistente

Universidad San Sebastián

Santiago, Chile

1
Gloria Arriagada

Profesor Asociado-Investigador Principal

Instituto de Ciencias Biomédicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile