Man

Eugenio Germán Spencer Ossa

DIRECTOR-INVESTIGADOR

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

Líneas de Investigación


InmunologÃa en salmoniformes y perciformes; Interacción patógeno-huésped en peces; Mecanismos moleculares asociados a resistencia a IPNV en salmón del atlántico; Biología molecular de virus animales responsables de patologías respiratorias y gastrointestinales; Patogenia de rotavirus, adenovirus y virus de la hepatitis A y C; Biología molecular y patogenia del virus ISA e IPN

Educación

  •  Molecular Biology, ALBERT EINSTEIN COLLEGE OF MEDICINE. Estados Unidos, 1979
  •  Bioquimica, ALBERT EINSTEIN COLLEGE OF MEDICINE. Estados Unidos, 1977

Experiencia Académica

  •   PROFESOR TITULAR Full Time

    UNIVERSIDAD DE SANTIAGO DE CHILE

    QUIMICA Y BIOLOGIA

    SANTIAGO, Chile

    1995 - A la fecha

Experiencia Profesional

  •   Director Científico Part Time

    ICTIO Biotechnologies

    Santiago, Chile

    2013 - A la fecha


 

Article (20)

Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant

Rivas-Aravena, A; Fuentes, Y; Cartagena, J; Brito, T; Poggio, V; La Torre, J; Mendoza, H; Gonzalez-Nilo, F; Sandino, AM; Spencer E.

Article ISI SCOPUS
Fish & Shellfish Immunology  (2015)

Development of a Reverse Genetic System for Infectious Salmon Anemia Virus: Rescue of Recombinant Fluorescent Virus by Using Salmon Internal Transcribed Spacer Region 1 as a Novel Promoter

Toro-Ascuy D.; Tambley, C; beltran, C; Mascayano, C; Sandoval, N.; Olivares, E.; Medina, R.A.; Spencer E.; Martina M.C.-S.

Article ISI SCOPUS
APPLIED AND ENVIRONMENTAL MICROBIOLOGY  (2015)

Ribavirin stimulates the immune response of Atlantic salmon

Rivas-Aravena, A; Guajardo, S; Valenzuela,B; Cartagena, J; Imarai M.I.; Spencer E.; Sandino, A.M.

Article ISI SCOPUS
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY  (2015)

Development of plaque assay for Chilean Infectious Salmon Anaemia Virus, application for virus purification and titration in salmon ASK cells

Castillo-Cerda M.T.; Cottet L.; Toro-Ascuy D.; Spencer E.; Cortez San Martín M.

Article ISI SCOPUS
JOURNAL OF FISH DISEASES  (2014)

Analysis of the use of codon pairs in the HE gene of the ISA virus shows a correlation between bias in HPR codon-pair use and mortality rates caused by the virus

Tello, M; Saavedra, JM; Spencer E.

Article ISI SCOPUS
Virology Journal  (2013)

Genomic adaptation of the ISA virus to Salmo salar codon usage

Tello, M; Vergara, F.; Spencer E.

Article ISI SCOPUS
Virology Journal  (2013)

Antiviral activity in vitro and in vivo of natural flavonoids isolated from Heliotropium sinuatum against infectious salmon anemia virus (ISAV)

Modak,B; Rivas, A; Vallejos, E.; Sandino, AM; Spencer E.

Article ISI
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS  (2012)

Evaluation of the immune response against immature viral particles of infectious pancreatic necrosis virus (IPNV): A new model to develop an attenuated vaccine

Rivas-Aravena, A; Martin M.C.S.; Galaz J.; Imarai M.; Miranda D.; Spencer E.; Sandino, A.M.

Article ISI SCOPUS
Vaccine  (2012)

Simultaneous detection of the IPN and ISA viruses in outbreaks of clinical disease and mortality in farmed Atlantic salmon, Salmo salar L., in Chile

Cortez San Martín M.; Rivas-Aravena, A; Guajardo, S; Castillo M.T.; Jashes, M.; Sandino, A.M.; Spencer E.

Article ISI SCOPUS
Journal of Fish Diseases  (2012)

Inhibitory effect of a nucleotide analog on infectious salmon anemia virus infection

Rivas-Aravena A.; Vallejos-Vidal E.; Martin M.C.-S.; Reyes-Lopez F.; Tello, M; Mora P.; Sandino, A.M.; Spencer E.

Article ISI SCOPUS
Journal of Virology  (2011)

Bioinformatic Analysis of the Genome of Infectious Salmon Anemia Virus Associated with Outbreaks with High Mortality in Chile

Cottet L.; Martin, MCS; Tello, M; Olivares, E.; Rivas-Aravena, A; Vallejos, E.; Sandino, AM; Spencer E.

Article ISI SCOPUS
JOURNAL OF VIROLOGY  (2010)

An ATPase activity associated with the rotavirus phosphoprotein NSP5

Bar-Magen, T; Spencer E.; Patton, JT

Article ISI SCOPUS
VIROLOGY  (2007)

Bioinformatic prediction of polymerase elements in the rotavirus VP1 protein

Carpio, RVD; Morales, JL; Barro, M; Ricardo, A.; Spencer E.

Article ISI SCIELO SCOPUS
BIOLOGICAL RESEARCH  (2006)

Differential usage of RNA templates by the rotavirus in vitro" replication system"

Barro, M; Bravo C.; Spencer E.

Article ISI SCOPUS
ARCHIVES OF VIROLOGY  (2004)

Role of the histidine triad-like motif in nucleotide hydrolysis by the rotavirus RNA-packaging protein NSP2

Del Carpio, RV; Gonzalez-Nilo, FD; Jayaram, H; Spencer E.; Prasad, BVV; Patton, JT; Taraporewala, ZF

Article ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2004)

Effect of neomycin B on rotavirus plus- and minus-strand RNA synthesis

Manchego, A; Spencer E.

Article ISI SCOPUS
ARCHIVES OF VIROLOGY  (2003)

NSP5 phosphorylation regulates the fate of viral mRNA in rotavirus infected cells

Chnaiderman J.; Barro, M; Spencer E.

Article ISI SCOPUS
ARCHIVES OF VIROLOGY  (2002)

Features of the 3'-consensus sequence of rotavirus mRNAs critical to minus strand synthesis

Chen, D.; Barros, M; Spencer E.; Patton, JT

Article ISI SCOPUS
VIROLOGY  (2001)

Identification of sequences in rotavirus mRNAs important for minus strand synthesis using antisense oligonucleotides

Barro, M; Mandiola, P; Chen, DY; Patton, JT; Spencer E.

Article ISI SCOPUS
VIROLOGY  (2001)

Specific subgroup B adenovirus diagnosis by PCR of the fibre gene

Bruzzone, MS; Fuentes, L; Spencer E.

Article ISI
JOURNAL OF INFECTION  (2000)

Abstract (3)

Antioxidant and immunostimulant evaluation of functional feed in Atlantic salmon under overcrowding stress

Reyes-Cerpa, S; Gonzalez-Bown, MJ; Carrasco-Malio, A; Dantagnan P.; Hernandez A.; Rodriguez, U; Borquez A.; Vidal, R; Spencer E.; Sandino, AM

Abstract ISI
FISH & SHELLFISH IMMUNOLOGY  (2013)

Evaluation of the immune and antioxidants response in Atlantic salmon fed with diets supplemented with yeast extract

Reyes-Cerpa, S; Gonzalez-Bown, MJ; Carrasco-Malio, A; Spencer E.; Sandino, AM

Abstract ISI
FISH & SHELLFISH IMMUNOLOGY  (2013)

The adjuvants have a key role improving the protection and immune response induced by recombinant protein vaccine against infectious salmon anemia virus ISAV in Atlantic salmon

Cortez San Martín M.; Cottet L.; Sandoval, N.; Toro-Ascuy D.; Rivas, A; Reyes-Cerpa, S; Acuna, C; Imarai M.; Sandino, AM; Spencer E.

Abstract ISI
FISH & SHELLFISH IMMUNOLOGY  (2013)

Review (4)

Infectious salmon anemia virus-Genetics and pathogenesis

Cottet L.; Rivas-Aravena, A; Cortez San Martín M.; Sandino, AM; Spencer E.

Review ISI SCOPUS
Virus Research  (2011)

Replication and transcription of the rotavirus genome

Patton, JT; Carpi, RVD; Spencer E.

Review ISI
CURRENT PHARMACEUTICAL DESIGN  (2004)

Identification of Adenovirus 7h Heterogeneity in the E3 Region

Bruzzone, M.; Barro, M; Spencer E.

Review ISI SCIELO SCOPUS
BIOLOGICAL RESEARCH  (2001)

Genome replication and packaging of segmented double-stranded RNA viruses

Patton, JT; Spencer E.

Review ISI
VIROLOGY  (2000)

27
Eugenio Spencer

DIRECTOR-INVESTIGADOR

BIOLOGIA

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

10
Ana Sandino

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

4
Luis Cottet

Investigador

Ciencias

Universidad Santo Tomas

Santiago, Chile

4
Mario Tello

Académico

Biología

Universidad de Santiago de Chile

Santiago, Chile

3
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Eduardo Olivares

Director area biomedicina

Diagnóstico molecular

Bioingentech

santiago, Chile

2
Julio Cartagena

2
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

1
Beatriz Valenzuela

Asistente de investigación/Profesor por Hora

Departamento de ciencias del ambiente

Universidad de Santiago de Chile

Santiago, Chile

1
Sergio Guajardo

Postdoctoral researcher

Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Carolina Beltrán

Postdoc

Virología

Universidad de Chile

Santiago, Chile

1
Rafael Medina

Associate Professor

Pediatrics

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Eva Vallejos

Profesor Asociado

Facultad de Medicina Veterinaria y Agronomía

Universidad de Las Américas

Santiago, Chile

1
Carolina Mascayano

Académico

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE QUÍMICA Y BIOLOGIA

santiago, Chile

1
Ruben Vidal

Profesor Asociado

Biologia

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
ADRIÁN HERNÁNDEZ

Profesor Asociado

Departamento de Ciencias Agropecuarias y Acuícolas

UNIVERSIDAD CATÓLICA DE TEMUCO, FACULTAD DE RECURSOS NATURALES

Temuco, Chile

1
Andrea Rivas

Investigadora

Universidad San Sebastián

Santiago, Chile

1
Brenda Modak

Directora Departamento de Ciencias del Ambiente

Departamento de Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
José Galaz

Estudiante de Posgrado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

1
Dante Miranda

Director de Extensión

Bioquímica y Biología Molecular

Universidad de Chile, Faculatd de Ciencias Químicas y Farmacéuticas

Santiago, Chile

1
Marcelo Cortez

Académico

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Jonas Chnaiderman

Profesor Asociado

Instituto de Ciencias Biomédicas

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Hegaly Mendoza

Académico

Universidad Andrés Bello

Santiago, Chile