PDI - Resultado de Búsqueda

Andreas Peter Schüller

Assistant Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Bioinformatics, cheminformatics, computational chemogenomics, prediction of protein-ligand interactions, prediction of protein-DNA interactions, computer-aided drug design, rational protein engineering, molecular modelling

Biochemistry, JOHANN WOLFGANG GOETHE UNIVERSITAT FRANKFURT. Alemania, 2004
Chemistry, JOHANN WOLFGANG GOETHE UNIVERSITAT FRANKFURT. Alemania, 2009

Postdoctoral Fellow Full Time

National University of Singapore

Duke-NUS Graduate Medical School

Singapur, Singapur

2008 - 2010
Postdoctorado FONDECYT Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biológicas

Santiago, Chile

2010 - 2012
Postdoctorado Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Intituto Milenio en Inmunologi?a e Inmunoterapia

Santiago, Chile

2012 - 2014

Investigador Adjunto Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2011 - 2015
Assistant Professor Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2015 - A la fecha
Independent Contractor Part Time

Merz Pharma GmbH & Co. KGaA

Frankfurt am Main, Alemania

2008 - 2008

PREGRADO

Claudio Ponce Acosta: "DETECTION OF PROTEIN-LIGAND BINDING SITE RESIDUES BY A PHYSICOCHEMICAL AND SPATIAL UNIQUENESS APPROACH", tesista bioquímica, Programa de Pregrado, Facultad de Ciencias Biológicas, UC. Inicio: 2018. Titulado: 2019

POSTGRADO

Daniela Herrera Toro: “Cambio en la selectividad y especificidad de la enzima resveratrol O-metiltransferasa (VvROMT) mediante ingeniería racional de proteínas y su aplicación en la biosíntesis de estilbenos”. Programa de Doctorado en Ciencias de la Ingeniería UC, Área Química y Bioprocesos. Inicio: 2016. Candidatura aprobada: 9 de enero de 2018. Tesis en cruso.

Andrés Ibacache Chia: "Diseño de inhibidores de transportadores de monocarboxilatos 1 y 4 mediante cribado virtual basado en ligandos y modelamiento por homología". Programa de Doctorado en Ciencias Biológicas UC, Mención Genética Molecular y Microbiología. Inicio: 2019.

Joaquín Gutiérrez Benavente: "Predicción de blancos biológicos por similitud química y estructural". Programa de Doctorado en Ciencias Biológicas UC, Mención Genética Molecular y Microbiología. Inicio: 2020.

Propiedad Intelectual - Registro de software
F. Melo, M. Lima, D. Bustamante, A. Schüller, F. Rodriguez, J. Cares, L. Almonacid: Sistema de Postulación en Línea a Programas de Postgrado – SPEL. Pontificia Universidad Católica de Chile. Departamento de Derechos Intelecuales, Inscripción Nº 252895, April 2015.


Calculation of accurate interatomic contact surface areas for the quantitative analysis of non-bonded molecular interactions Ribeiro, Judemir; Ríos-Vera, Carlos; Melo, Francisco; Schüller, Andreas Article ISI SCOPUS BIOINFORMATICS (2019)
Exploring DNA dynamics within oligonucleosomes with coarse-grained simulations: SIRAH force field extension for protein-DNA complexes Brandner, Astrid; Schüller, Andreas; Melo, Francisco; Pantano, Sergio Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3 beta: autoregulation of GSK-3 beta in vivo Tapia-Rojas, C; Schuller, A; Lindsay C.B.; Ureta R.C.; Mejias-Reyes C.; Hancke, J; Melo F.; Inestrosa, N. C. Article ISI SCOPUS BIOCHEMICAL JOURNAL (2015)
PDIviz: analysis and visualization of protein-DNA binding interfaces Ribeiro J.; Melo F.; Schuller, A Article ISI SCOPUS Bioinformatics (2015)
Tetrahydrohyperforin: a neuroprotective modified natural compound against Alzheimer's disease Montecinos-Oliva, C; Schuller, A; Inestrosa, NC Article ISI SCOPUS Neural Regeneration Research (2015)
Effects of Tetrahydrohyperforin in Mouse Hippocampal Slices: Neuroprotection, Long-term Potentiation and TRPC Channels Montecinos-Oliva, C.; Schueller, A.; Parodi, J.; Melo, F.; Inestrosa, N. C. Article ISI CURRENT MEDICINAL CHEMISTRY (2014)
Exploring the binding of peptidic West Nile virus NS2B-NS3 protease inhibitors by NMR Kang, CB; Gayen, S; Wang, WL; Severin, R; Chen, AS; Lim, HA; Chia, CSB; Schuller, A; Doan, DNP; Poulsen, A; Hill J.; Vasudevan, SG; Keller, TH Article ISI SCOPUS Antiviral Research (2013)
Computer-Based Annotation of Putative AraC/XylS-Family Transcription Factors of Known Structure but Unknown Function Schuller, A; Slater, A.W.; Norambuena, T; Cifuentes J.J.; Almonacid, L.I.; Melo F. Article ISI SCOPUS Journal of Biomedicine and Biotechnology (2012)
Structure-guided fragment-based in silico drug design of dengue protease inhibitors Knehans, T; Schuller, A; Doan, DN; Nacro, K; Hill J.; Guntert, P; Madhusudhan, MS; Weil, T; Vasudevan, SG Article ISI JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2011)
Tripeptide inhibitors of dengue and West Nile virus NS2B-NS3 protease Schuller, A; Yin Z.; Chia, CSB; Doan, DNP; Kim, HK; Shang, LQ; Loh, TP; Hill J.; Vasudevan, SG Article ISI SCOPUS Antiviral Research (2011)
Adaptive Combinatorial Design of Focused Compound Libraries Schneider, Gisbert; Schueller, Andreas; Roque, ACA Article ISI NEISSERIA MENINGITIDIS (2010)
Amino Derivatives of Indole As Potent Inhibitors of Isoprenyleysteine Carboxyl Methyltransferase Go, ML; Leow, JL; Gorla, SK; Schuller, AP; Wang, M; Casey, PJ Article ISI JOURNAL OF MEDICINAL CHEMISTRY (2010)
Isozyme-Specific Fluorescent Inhibitor of Glutathione S-Transferase Omega 1 Son, J; Lee, JJ; Lee, JS; Schuller, A; Chang, YT Article ISI ACS CHEMICAL BIOLOGY (2010)
Quantitative Structure-Fluorescence Property Relationship Analysis of a Large BODIPY Library Schuller, A; Goh, GB; Kim, H; Lee, JS; Chang, YT Article ISI MOLECULAR INFORMATICS (2010)
Concept of combinatorial De novo design of drug-like molecules by particle swarm optimization Hartenfeller, Markus; Proschak, Ewgenij; Schueller, Andreas; Schneider, Gisbert Article ISI CHEMICAL BIOLOGY & DRUG DESIGN (2008)
Identification of hits and lead structure candidates with limited resources by adaptive optimization Schueler, Andreas; Schneider, Gisbert Article ISI JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA Schueller, Andreas; Suhartono, Marcel; Fechner, Uli; Tanrikulu, Yusuf; Breitung, Sven; Scheffer, Ute; Goebel, Michael W.; Schneider, Gisbert Article ISI JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2008)
Molecular query language (MQL) - A context-free grammar for substructure matching Proschak, Ewgenij; Wegner, Joerg K.; Schueller, Andreas; Schneider, Gisbert; Fechner, Uli Article ISI JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)
SmiLib v2.0: A Java-based tool for rapid combinatorial library enumeration Schueller, Andreas; Haehnke, Volker; Schneider, Gisbert Article ISI QSAR COMBINATORIAL SCIENCE (2007)
A pseudo-ligand approach to virtual screening Schueller, Andreas; Fechner, Uli; Renner, Steffen; Franke, Lutz; Weber, Lutz; Schneider, Gisbert Article ISI COMBINATORIAL CHEMISTRY HIGH THROUGHPUT SCREENING (2006)
SMILIB: Rapid assembly of combinatorial libraries in SMILES notation Schuller, A; Schneider, G; Byvatov, E Article ISI QSAR COMBINATORIAL SCIENCE (2003)