Man

Jorge Alejandro Gonzalez Cortes

Profesor Titular

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

Líneas de Investigación


Invasión celular en Trypanosoma cruzi; Transducción de señales en protozoos parásitos; Bioquímica celular de protozoos parásitos; Búsqueda y evaluación de compuestos con actividad tripanocida; Proteómica de Trypanosoma cruzi

Educación

  •  Tecnologo Médico, UNIVERSIDAD DE CHILE. Chile, 1980
  •  Ciencias, Universidad Federal Paulista. Brasil, 1991

Experiencia Académica

  •   Profesor Titular Full Time

    UNIVERSIDAD DE ANTOFAGASTA

    Ciencias de la Salud

    Antofagasta, Chile

    1980 - A la fecha


 

Article (65)

Observational cross-sectional study of Trichomonas tenax in patients with periodontal disease attending a Chilean university dental clinic
Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of and spiders.
Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes.
Decreased cruzipain and gp85/trans-sialidase family protein expression contributes to loss of Trypanosoma cruzi trypomastigote virulence
Phospholipase D from Loxosceles laeta Spider Venom Induces IL-6, IL-8, CXCL1/GRO-α, and CCL2/MCP-1 Production in Human Skin Fibroblasts and Stimulates Monocytes Migration.
Role of the Ubiquitin-Proteasome Systems in the Biology and Virulence of Protozoan Parasites
A cytoplasmic new catalytic subunit of calcineurin in Trypanosoma cruzi and its molecular and functional characterization.
Aromatic glycosyl disulfide derivatives: Evaluation of their inhibitory activities against Trypanosoma cruzi..
Role of gap junctions and hemichannels in parasitic infections.
In vitro and in vivo trypanocidal activity of native plants from the Yucatan Peninsula.
A protein phosphatase 1 gamma (PP1γ) of the human protozoan parasite Trichomonas vaginalis is involved in proliferation and cell attachment to the host cell.
Extensive Genetic Diversity, Unique Population Structure and Evidence of Genetic Exchange in the Sexually Transmitted Parasite Trichomonas vaginalis.
How to invade, replicate, and escape from host organisms. A challenge in defining virulence factors for parasites.
Metabolites from the leaf extract of Serjania yucatanensis with trypanocidal activityagainst Trypanosoma cruzi.
Virulence factors of Trypanosoma cruzi: who is who?
N,N'-Dithiobisphthalimide, a disulfide aromatic compound, is a potent spermicide agent in humans.
Two new phospholipase D isoforms of Loxosceles laeta: Cloning, heterologous expression, functional characterization, and potential biotechnological application.
Tetracycline and penicillin resistant Clostridium perfringens isolated from the fangs and venom glands of Loxosceles laeta: its implications in loxoscelism treatment.
Effectiveness of a repellent paint against the spider Loxosceles laeta
Molecular characterization and intracellular distribution of the alpha 5 subunit of Trypanosoma cruzi 20S proteasome.
Calcineurin B of human protozoan parasite Trypanosoma cruzi is involved in the cell invasión.
Descenlace fatal por loxoscelismo cutáneo visceral.
A novel protein phosphatase 2A (PP2A) is involved in the transformation of human protozoan parasite Trypanosoma cruzi.
Diterpenoids from Azorella compacta (Umbelliferae) active on Trypanosoma cruzi.
Azorellane diterpenoids from Lareta acaulis, and its toxoplasmacidal activity
Diterpenoids from Azorella yareta and their trichomonicidal activities
La enseñanza de postgrado en la Facultad de Ciencias de la Salud.
Nuevos casos de infección humana por Diphyllobothrium pacificum (Nybelin, 1931) Margolis, 1956 in el Norte de Chile, probablemente relacionados con el fenómeno de El Niño, 1975-2000.
The ubiquitin-proteasome pathway plays an essential role in proteolysis during Trypanosoma cruzi remodeling
Diphyllobothriosis humana por infección por Diphyllobothrim pacificum en un niño de 3 años en Antofagasta.
Fosforilación en células eucarióticas. Papel de fosfatasas y quinasas en la biología, patogenia y control de protozoosis tisulares y sanguíneas.
Mepraia spinolai in the southeastern pacific ocean coast (Chile)-First insular record and feeding pattern on the Pan de Azúcar Island.
Enteroparasitosis in the north of Chile. II. Coproparasitological survey in children of altiplanic communities.
Proteosomes, un complejo enzimático multicatalítico en busca de nuevas funciones.
Proteasome function is required for encystation of Entamoeba invadens
Vigilancia serológica de la transmisión congénita de la enfermedad de Chagas en Antofagasta-Chile.
Anti- gal antibodies in chilean population infected by Trypanosoma cruzi.
Proteasome activity is required for the stage-specific transformation of a protozoan parasite.
Serum antibodies to Trypanosoma cruzi antigen in atacamenos patients from highlands of northern.
Biochemical, immunological and biological characterization of Trypanosoma cruzi populations of the Andean north of Chile.
Chagas’ disease in northern Chile. Serological prevalence in pregnance women from Antofagasta city, 1991-1993.
The 35/50 kDa surface antigen of Trypanosoma cruzi metacyclic trypomastigote, an adhesion molecule involved in host cell invasion.
Participation of antibodies in the protection against Trypanosoma cruzi infection.
Algunas reflexiones acerca de la investigación cientifica en las universidades derivadas.
In vitro activity of natural products against the trypomastigote forms of Trypanosoma cruzi
Resistance to acute Trypanosoma cruzi infection resulting from immunization of mice with a 90-kilodalton antigen from metacyclic trypomastigote
Proteosome-dependent cyst formation and stage-specific ubiquitin mRNA accumulation in Entamoeba invadens.
The stage-specific 90 kilodalton surface antigen of metacyclic trypomastigotes of Trypanosoma cruzi
Metacyclic neutralizing effect of monoclonal antibody 10D8 directed to the 35 and 50 kilodalton surface glycoconjugate of Trypanosoma cruzi
A new method for the aethiological diagnosis of human scabies.
Chagasic cardiomyopathy in Chilean highland.
Cryptosporidiosis in the north of Chile. I. Prevalence in domestic, synantropic and wild animals.
Cryptosporidiosis in the north of Chile. II Prevalence in infants with acute diarrhea.
First report of Anisakis simplex (Rudolphi, 1809, det Krabbe 1878) from the dolphin Tursiops truncatus (Montagu, 1821), stranded at Antofagasta, Chile.
Trypanosoma cruzi infection among habitants of non Andean plateau areas in the second region-Antofagasta (1983-1985).
An evaluation of the direct agglutination test for diagnosis of Chagas’ disease.
Chagas’ disease in Chile. Seroepidemiological study in 5 blood banks from the II region, Antofagasta. Antofagasta -1985
ELISA test for the diagnosis of American trypanosomiasis. Limit absorbances for reacting and non reacting sera.
Enteroparasitosis in the north of Chile. I. Prevalence in fishers of several port of the II region. Antofagasta.
Yielding of SAF method modification for enteroparasitological diagnosis.
Yielding of the indirect hemagglutination test for the diagnosis of Chagas’ disease in sera and filter paper eluates
Diagnosis of trichomoniasis: Evaluation of techniques for collection and transport of samples.
Epidemiological survey of toxoplasmosis by an intradermal test in universitary students
Chagasic seropositivity in a blood bank in a endemic area. Some epidemiological aspects of the blood donors.
Enteroparasitological survey among foods manipulators in Antofagasta city.

Abstract (3)

POPULATION GENOMICS OF TRICHOMONAS VAGINALIS REVEALS A GLOBALLY DISTRIBUTED TWO-PHYLOTYPE POPULATION STRUCTURE
POPULATION GENOMICS OF THE SEXUALLY TRANSMITTED HUMAN PATHOGEN TRICHOMONAS VAGINALIS
The COP9 signalosome of Trypanosoma cruzi

BookSection (1)

Role of Proteomics in the Study of Trypanosoma cruzi

ComunicacionBreve (1)

Nuevos casos de infección humana por Diphyllobothrium pacificum (Nybelin, 1931) Margolis, 1956 en Chile y su probable relación con el fenómeno de El Niño, 1975-2000

Review (3)

Role of the Ubiquitin-Proteasome Systems in the Biology and Virulence of Protozoan Parasites
Role of Gap Junctions and Hemichannels in Parasitic Infections
Phosphorylation in eukaryotic cells. Role of phosphatases and kinases in biology, pathogenesis and control of intracellular and bloodstream protozoa
12
Jorge Gonzalez

Profesor Titular

Departamento de Tecnología Médica

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

6
Jorge Araya

Profesor Asociado

Departamento de Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

2
Christian Muñoz

Profesor Asistente

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Héctor Varela

PROFESOR TITULAR

MATEMATICAS

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile

1
Alejandro Catalán

Academico Jornada Completa

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
AURELIO SAN MARTIN

Profesor Asociado (media jornada)

de Ciencias y Recursos Naturales

FACULTAD DE CIENCIAS

Punta Arenas, Chile

1
Joel Bravo

Profesor Asociado

Odontología

Universidad de Antofagasta

Antofagasta, Chile