Man

Carolina Andrea Sanchez Doñas

Assistant Professor, Faculty of Science; Principal Investigator of Advanced Genomics Laboratory; Head of DNA Sequencing Core of the Center for Genomics and Bioinformatics

Universidad Mayor

Santiago, Chile

Líneas de Investigación


Plant Genomics and Biotechnology; Applications of Next Generation Sequencing in many fields related to the biological sciences; Develop, improve and adapt strategies based on Next Generation Sequencing; Pharmacogenomics and Personalized Medicine

Educación

  •  Biochemistry, Licenciado. Chile, 1999
  •  Biotechnology, UNIVERSIDAD TECNICA FEDERICO SANTA MARIA. Chile, 2008
  •  Biochemical, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD MAYOR

    Faculty of Science

    Santiago, Chile

    2011 - At present

  •   Professor of the Integrative Genomics PhD Program Other

    UNIVERSIDAD MAYOR

    Faculty of Science

    Santiago, Chile

    2014 - At present

  •   Member of the Curriculum Committee of the Biotechnology Career Other

    UNIVERSIDAD MAYOR

    Faculty of Science

    Santiago, Chile

    2017 - 2017

  •   Internal Professor Invited as Evaluator of Competences Graduate level of the Biotechnology Degree Other

    UNIVERSIDAD MAYOR

    Faculty of Science

    Santiago, Chile

    2015 - 2018

  •   Member of the Accreditation Review Committee of the Integrative Genomics PhD Program Other

    UNIVERSIDAD MAYOR

    Faculty of Science

    Santiago, Chile

    2014 - 2014

Experiencia Profesional

  •   Assistant Research Full Time

    Saint Louis University

    Saint Louis, Estados Unidos

    2010 - 2010

  •   Assistant Research Other

    Washington University

    Saint Louis, Estados Unidos

    2009 - 2009

  •   Graduate Research Full Time

    Biotechnology Center “Dr. Daniel Alkalay Lowitt”. Universidad Técnica Federico Santa María

    Valparaíso, Chile

    2004 - 2006

  •   Graduate Research Fellowship Other

    Albrecht-von-Haller-Institute for Plant Sciences, Dept. for Plant Biochemistry, Georg-August-University of Goettingen.

    Goettingen, Alemania

    2006 - 2006

  •   Research Assistant Other

    Biotechnology Center “Dr. Daniel Alkalay Lowitt”. Universidad Técnica Federico Santa María

    Valparaíso, Chile

    2002 - 2003

  •   Lab manager/Research Assistant Full Time

    Plant Physiology & Plant Molecular Genetics Laboratory, Faculty of Sciences. Universidad de Chile

    Santiago, Chile

    2000 - 2001

  •   Undergraduate Research/Teaching Assistant Full Time

    Plant Physiology and Molecular Biology Laboratory, Chemistry and Biology Faculty at Universidad de Santiago de Chile

    Santiago, Chile

    1998 - 1999

  •   Management and development of the Next Generation Sequencing process of lung cancer samples Full Time

    Universidad Mayor/Genoma Mayor and CEMP

    Santiago, Chile

    2015 - 2017

  •   Head of Sequencing Core Full Time

    Universidad Mayor/Center for Genomics and Bioinformatics

    Santiago, Chile

    2011 - At present

  •   Asistant Professor/Advanced Genomics Laboratory Full Time

    Universidad Mayor/Center for Genomics and Bioinformatics

    Santiago, Chile

    2011 - At present

Formación de Capital Humano


1. Co-Director of the undergraduate Thesis "Search of clinical predictors for the diagnosis of Epidermolysis bullosa (EB): emphasis on infection and wound closure". Biotechnology career, School of Biotechnology, Universidad Mayor. 1 student.
2.2018-2019. Director of the undergraduate Thesis "Genetic analysis of the extinct plant Sophora toromiro as a first step to its reinsertion in Rapa Nui". Biotechnology career, School of Biotechnology, Universidad Mayor. 1 student.
3. 2019. Management of candidate PhD student. March-November. Medicine career, Universidad de Chile. 1 student.
4.2019. Management of Professional practice. January-March. Biotechnology career, School of Biotechnology, Universidad Mayor. 1 student.
5. 2019. Management of students of Summer Internships. December-January. Biotechnology career, School of Biotechnology, Universidad Mayor. 3 students.
6. 2018. Mangement of students of Summer Internships. January. Biotechnology career, School of Biotechnology, Universidad Mayor. 2 students.
7. 2018. Tutor Professor: Course in Precision Medicine and Genomics, II Semester. Doctorate in Integrative Genomics. 48 hours. Theoretical and Applied Teaching. 1 student.
8. 2018. Professor in charge of Research Seminar I. Doctorate in Integrative Genomics. II Semester. 48 hours. Supervision and development of a PhD student research project. 1 student.
9. 2018. Participation in the Evaluation Committee of the Undergraduate Thesis "Role of regulatory modules miR156 / SPL and miR172 / AP2 during nitrogen deficit in root of Arabidopsis thaliana root".
10. 2018. Participation in the Evaluation Committee of the Undergraduate Thesis "Study of the expression of genes related to the metabolism of malic acid in table grapes (Vitis vinifera L.).


Difusión y Transferencia


7-18 January 2019. Summer Course: "Microbes on your cell phone? You stick them! An analysis of the microbiota shared with our telephone devices?. Developed in conjunction with the School of Biotechnology / Major Genome. Talent School U Major 2019.

October 24-28, 2018. Visit to the Universidad Mayor / Genoma Mayor University of the Andes of Colombia. University of the Andes. Bogota Colombia.

September 2018. Participation in a program of scientific dissemination, Explorers: from the atom to the cosmos. Channel 24 hours. How has genomics impacted in medicine? .Https: //www.youtube.com/watch? V = bUGgYwvLZEo.

May 31, 2018. Daily publication El Mostrador. Title: They seek to reverse the extinction of the sacred tree Rapa Nui by rebuilding its genetic fingerprint http://www.elmostrador.cl/cultura/2018/05/31/buscan-revertir-extincion-de-arbol-sagrado-rapa-nui-reconstruyendo- your-genetic-footprint /.

May 30 2018. Daily publication The Latest News. Pag: 10, Art 2. Title: Seek to sequence the shrub genome that became extinct in Easter Island, http: //www.lun.com/Pages/NewsDetail.aspx? Dt = 2018-05-30 & PaginaId = 10 & bodyid = 0.

April 25, 2018. 2nd Meeting of the Toromiro Technical Group/Conaf/JBN. Meeting Room, Badajoz 130, Las Condes, Universidad Mayor. Santiago.

February 19, 2018. La Tercera daily publication. Title: They seek to decipher genetics of the extinct Easter Island tree. http://www.latercera.com/tendencias/noticia/buscan-descifrar-genetica-extinto-arbol-islapascua/72337/.

2 February 2018. Publication RedBionova. Title: Scientific project will clarify the genetic situation of the toromiro, extinct endemic tree of Easter Island. http://www.redbionova.com/proyecto-cientifico-esclarecera-la-situacion-genetica-del-toromiro-arbol-endemico-extinto-isla-pascua/.

October 19, 2017. Participation as a reviewer of written projects and poster format in the XII Regional School Congress of Science and Technology Explora, organized by the PAR Explore of CONICYT South East Metropolitan Region of the University of Chile. Faculty of Physical and Mathematical Sciences of the University of Chile. Beaucheff 851, Santiago.

19-20 July 2017. Meeting of the International University of the Andes of Colombia and Genoma Mayor. Sequencing Unit-Major Genome, Huechuraba Campus, Universidad Mayor.

November 9, 2016. Participation in the "One Day with One Scientist" initiative for the Explora Regional Associative Project RM Zona Sur Oriente.


Premios y Distinciones

  •   Graduate Research Fellowship, Foreign Research Centers

    Mecesup

    Chile, 2006

    Fellowship to do an internship in a Foreign Research Centers. I went to Albrecht-von-Haller-Institute for Plant Sciences, Dept. for Plant Biochemistry, Georg-August-University of Goettingen. Determined oxylipins levels by combinations of HPLC, GC, GC/MS and LC/MS.


 

Article (5)

Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
Draft Genome Sequences of Five Enterococcus Species Isolated from the Gut of Patients with Suspected Clostridium difficile Infection
High quality RNA extraction from Maqui berry for its application in next-generation sequencing
Deep Sequencing Reveals the Complete Genome and Evidence for Transcriptional Activity of the First Virus-Like Sequences Identified in Aristotelia chilensis (Maqui Berry)
Draft genome of Chilean honeybee (Apis mellifera) gut strain Lactobacillus kunkeei MP2

Proyecto (9)

Clinical Exome Sequencing for Genetic Identification of West Syndrome.
GENETIC ANALYSIS OF THE EXTINCT TOROMIRO TREE AS A FIRST APPROACH TO ITS REINTRODUCTION IN RAPA NUI.
TECHNOLOGICAL CONTRACTS FOR INNOVATION
Clinical, imaging, histological and genetic characterization of a family with CADASIL in CHILE.
Methylation of MGMT (o6-methylguanine-dna methyltransferase) in patients with glioblastoma multiforme.
Non-Interventional Multicenter Study for the Validation of Molecular Diagnostic Technology in Patients with Non-Small Cell Lung Cancer.
A Study of Genotyping of bovine
Genomic analysis of the extinct plant in its natural habitat Sophora toromiro for the identification of species and hybrids as a first step to its conservation and reintroduction in Rapa Nui.
Molecular profiling in glioblastoma

Review (1)

Involvement of jasmonic acid and derivatives in plant responses to pathogens and insects and in fruit ripening
15
Carolina Sanchez

Assistant Professor, Faculty of Science; Principal Investigator of Advanced Genomics Laboratory; Head of DNA Sequencing Core of the Center for Genomics and Bioinformatics

Center for Genomics and Bioinformatics

Universidad Mayor

Santiago, Chile

2
Víctor Polanco

Vicerrector de Investigación, Creación Artística y Doctorado

Vicerrectoría de Investigación, Creación Artística y Doctorado

Universidad Finis Terrae

Santiago, Chile

2
Vinicius Ramos Henriques

Associate Professor

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

1
FERNANDO DORTA

APOYO ACADÉMICO

CENTRO DE BIOTECNOLOGIA

Universidad Técnica Federico Santa María

VALPARAÍSO, Chile

1
Maria Matus

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

1
Mario Moreno

Estudiante doctoral

Facultad de Ciencias

Centro GEMA -Genómica, Ecología y Medio Ambiente

Santiago, Chile

1
Eduardo Castro

Professor

Departamento de Microbiología

Universidad de Talca

Talca, Chile

1
Jose Matamala

Assistant Professor of Neurology

Department of Neurological Science

University of Chile

Santiago, Chile

1
Patricio Manque

VICE PRESIDENT FOR RESEARCH AND FULL PROFESSOR

UNIVERSIDAD MAYOR

Santiago, Chile

1
Sandro Valenzuela

Bioinformático

Bioinformática

Multiplex SpA

Santiago, Chile

1
Elizabeth Sanchez

INVESTIGADOR

UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

ValparaísO, Chile