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Rodrigo Alfonso Somoza Palacios

Senior Research Associate

Case Western Reserve University

Cleveland, Estados Unidos

- Somatic Stem Cell Biology - Cancer Metastasis - Tissue Engineering (scaffold design, stem cells applications) - Cell Therapy and Tissue Regeneration - Biosensor development - Reprogramming Technology (IPS) - Growth Factor Production

Researcher Other

Universidad del Desarrollo

Santiago, Chile

2007 - 2008
Researcher-PhD(c) Other

UNIVERSIDAD TECNICA FEDERICO SANTA MARIA

Valparaiso, Chile

2010 - 2012
Research Associate Full Time

CASE WESTERN RESERVE UNIVERSITY

Cleveland, Estados Unidos

2012 - 2015
Senior Research Associate, Director Cell Culture Facility, Director TR&D2 Program CCMECC Full Time

CASE WESTERN RESERVE UNIVERSITY

Cleveland, Estados Unidos

2015 - At present

Profesor de Cátedra Part Time

Universidad Andres Bello

Viña del Mar, Chile

2011 - 2012


Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1 Nossin, Yannick; Farrell, Eric; Koevoet, Wendy J. L. M.; Somoza, Rodrigo A.; Caplan, Arnold I.; Brachvogel, Bent; van Osch, Gerjo J. V. M. Article ISI FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Transcriptome dynamics of long noncoding RNAs and transcription factors demarcate human neonatal, adult, and human mesenchymal stem cell-derived engineered cartilage Vail, Daniel J.; Somoza, Rodrigo A.; Caplan, Arnold, I; Khalil, Ahmad M. Article ISI JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2020)
Analysis of-5p and-3p Strands of miR-145 and miR-140 During Mesenchymal Stem Cell Chondrogenic Differentiation Kenyon, Jonathan D.; Sergeeva, Olga; Somoza, Rodrigo A.; Li, Ming; Caplan, Arnold I.; Khalil, Ahmad M.; Lee, Zhenghong Article ISI TISSUE ENGINEERING PART A (2019)
Human mesenchymal stem cells induced to differentiate as chondrocytes follow a biphasic pattern of extracellular matrix production Sorrell, J. Michael; Somoza, Rodrigo A.; Caplan, Arnold I. Article ISI JOURNAL OF ORTHOPAEDIC RESEARCH (2018)
Nondestructive/Noninvasive Imaging Evaluation of Cellular Differentiation Progression During In Vitro Mesenchymal Stem Cell-Derived Chondrogenesis Correa, Diego; Somoza, Rodrigo A.; Caplan, Arnold I. Article ISI TISSUE ENGINEERING PART A (2018)
Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered Cartilage Somoza, Rodrigo A.; Correa, Diego; Labat, Ivan; Sternberg, Hal; Forrest, Megan E.; Khalil, Ahmad M.; West, Michael D.; Tesar, Paul; Caplan, Arnold I. Article ISI TISSUE ENGINEERING PART A (2018)
TGF beta 3 secretion by three-dimensional cultures of human dental apical papilla mesenchymal stem cells Somoza, R. A.; Acevedo, C. A.; Albornoz F; Luz-Crawford P.; Carrión F.; Young M.E.; Weinstein-Oppenheimer C. Article ISI SCOPUS JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)
Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases Dave, Maneesh; Menghini, Paola; Sugi, Keiki; Somoza, Rodrigo A.; Lee, Zhenghong; Jain, Mukesh; Caplan, Arnold; Cominelli, Fabio Article ISI JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2017)
Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche Correa, Diego; Somoza, Rodrigo A.; Lin, Paul; Schiemann, William P.; Caplan, Arnold I. Article ISI INTERNATIONAL JOURNAL OF CANCER (2016)
Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation Correa, D.; Somoza, R. A.; Lin, P.; Greenberg, S.; Rom, E.; Duesler, L.; Welter, J. F.; Yayon, A.; Caplan, A. I. Article ISI OSTEOARTHRITIS AND CARTILAGE (2015)
Chondrogenic Differentiation of Mesenchymal Stem Cells: Challenges and Unfulfilled Expectations Somoza, Rodrigo A.; Welter, Jean F.; Correa, Diego; Caplan, Arnold I. Article ISI TISSUE ENGINEERING PART B-REVIEWS (2014)
Improvement of human skin cell growth by radiation-induced modifications of a Ge/Ch/Ha scaffold Acevedo, CA; Somoza RA; Weinstein-Oppenheimer C.; Silva, S; Moreno, M.; Sanchez E.; Albornoz F; Young, ME; MacNaughtan, W; Enrione, J Article ISI SCOPUS Bioprocess and Biosystems Engineering (2013)
Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer Enrione, J; Osorio, F; López, D; Weinstein-Oppenheimer C.; Fuentes, MA; Ceriani, R.; Brown, DI; Albornoz F; Sanchez E.; Villalobos, P.; Somoza RA; Young, ME; Acevedo, CA Article ISI SCIELO SCOPUS ELECTRONIC JOURNAL OF BIOTECHNOLOGY (2010)
Growth factor production from fibrin-encapsulated human keratinocytes Acevedo, CA; Somoza RA; Weinstein-Oppenheimer C.; Brown, DI; Young, ME Article ISI SCOPUS Biotechnology Letters (2010)
Intranigral Transplantation of Epigenetically Induced BDNF-Secreting Human Mesenchymal Stem Cells: Implications for Cell-Based Therapies in Parkinson's Disease Somoza, R; Juri C.; Baes, M; Wyneken, U; Rubio, FJ Article ISI SCOPUS Biology of Blood and Marrow Transplantation (2010)
Neuropotency of human mesenchymal stem cell cultures: Clonal studies reveal the contribution of cell plasticity and cell contamination Somoza, R; Conget P.; Rubio, FJ Article ISI SCOPUS BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2008)


Cell therapy using induced pluripotent stem cells or somatic stem cells: This is the question Somoza, R. A.; Rubio F.J. Review ISI SCOPUS Current Stem Cell Research & Therapy (2012)