Emma Marcela Hernandez Ríos
Académico 44 h, profesor titular
Universidad de Chile, Facultad de Odontología
SANTIAGO, Chile
Etiology and pathogenesis of periodontitis from periodontal and endodontic origin, their systemic complications and identification of biomarkers in oral fluids
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dental sciencies, UNIVERSITY OF HELSINKI. Finlandia, 2012
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Dental Sciences Mention Oral Pathology, UNIVERSIDAD DE CHILE. Chile, 2006
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SPECIALIST IN ORAL PATHOLOGY AND MEDICINE, UNIVERSIDAD DE CHILE. Chile, 2012
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DENTIST, UNIVERSIDAD DE CHILE. Chile, 1998
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Dentistry, UNIVERSIDAD DE CHILE. Chile, 1998
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Profesor titular Full Time
UNIVERSIDAD DE CHILE
ODONTOLOGIA
SANTIAGO, Chile
2001 - At present
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Associate researcher Part Time
Universidad Autónoma de Chile
Cs. de la Salud
Santiago, Chile
2016 - 2019
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Member of the study group medicine G2-G3 National fund of scientific and technological development Part Time
FONDECYT
Santiago, Chile
2016 - At present
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Director of the Doctorate Program of dental sciences Full Time
UNIVERSIDAD DE CHILE
Santiago, Chile
2013 - 2019
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Chief of Anatomic Pathology Service Full Time
Universidad de Chile
Santiago, Chile
2017 - At present
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Specialist in Oral Pathology and Medicine Part Time
Hospital Clínico Universidad de Chile
Santiago, Chile
2019 - At present
Undergraduate thesis supervision
1. "Role of the O antigen of the lipopolysaccharide of Porphyromonas gingivalis in the profile of differentiation of macrophages". Student: Alfredo Ignacio Castro Martínez. 2019. Financing: FONDECYT 1160741.
2. Cardiovascular risk associated with systemic inflammation in patients with asymptomatic apical periodontitis. Student: Francisca Quinlan Binelli, year 2019. Financing: FONDECYT 1160741.
3. Levels of expression of toll-4 receptor (TLR-4), interleukin (IL) -10 and IL-12 in peripheral blood mononuclear cells of patients with asymptomatic apical periodontitis. Student: Lynn Barstow Melgarejo, year 2019. Financing: FONDECYT 1160741.
4. Role of the O antigen of the lipopolysaccharide of Porphyromonas gingivalis in the profile of differentiation of macrophages. Student: Alfredo Castro Martínez, year 2019. Financing: FONDECYT 1160741.
5. Immunolocalization of the signaling complex of interleukin-6 in periapical lesions of endodontic origin. Student: Catalina Schweitzer Gatica, year 2019. Financing: FONDECYT 1160741.
6. Prevalence of teeth treated endodontically in a Chilean subpopulation. Student: Macarena Becker Pinto, year 2018. Financing: FONDECYT 1160741. 2018.
7. "Humoral immune response and endotoxemia in endodontic infection with Porphyromonas endodontalis and Porphyromonas gingivalis in Asymptomatic Apical Periodontitis. "Dept. of Pathology and Oral Medicine. University of Chile. Student: student: Valeska Fariña Espinosa. Year 2015. Financing: FONDECYT 1120138.
8. "Morphological and Molecular Characterization of Mandibular Temporomal Ankylosis". Dept. of Pathology and Oral Medicine. University of Chile. Student: student Rubén Soto Galaz. Year 2015. Financing: FIOUCH13-004.
9. "Levels of Tartrate-Resistant Acid Phosphatase (TRAP), Ligand Activating Receptor for the Nuclear Factor NFkB (RANKL) and Osteoprotegerin (OPG) in Symptomatic and Asymptomatic Periapical Lesions of Endodontic Origin". Dept. of Pathology and Oral Medicine. University of Chile. Student: Macarena Salinas Muñoz. Year 2015. Financing: FONDECYT 1120138
10. Myeloperoxidase (MPO) levels in Periapical Lesions of Endodontic Origin. Dept. of Pathology and Oral Medicine. University of Chile. Student: Marcela Bolbarán Gómez. Main tutor Year 2014. FONDECYT financing 1120138.
11. C-Reactive Protein in Apical Lesions of Endodontic Origin. Department of Conservative Dentistry and Pathology and Oral Medicine. University of Chile. María José Bordagaray Principal Tutor. Year 2013. Financing FONDECYT 1120138.
12. "Association between Asymptomatic Apical Periodontitis and Modifiable Risk Factors of Cardiovascular Diseases" Germán Contreras Silva Associate Tutor. Financing FONDECYT 1120138. Year 2013.
13. "Levels of Myeloperoxidase (MPO) in Periapical Teeth Exudate with Asymptomatic Apical Periodontitis (PAA) Measured Pre and Post-Endodontic Medications with Calcium Hydroxide". Josefa Belén Castro Salas. Associate tutor. Year 2013. Financing FONDECYT 1120138.
14. Tissue Localization of Matrix Metalloproteinase -12 in Periapical Lesions Consecutive to Septic Pulp Necrosis and Healthy Periapical Tissue, Student: Pilar Jerez. School of Dentistry University of Chile. Associate tutor. Year 2012. Financing FONDECYT 1090461.
15. Levels of Myeloperoxidase (MPO) in Crevicular Gingival Fluid (FGC) of Teeth with Asymptomatic Apical Periodontitis (PAa). Student: Valentina Aranda González. Responsible tutor Year 2012. Financing FONDECYT 1090461.
16. Thesis Levels of Crosslinked Piridinoline of Type I Colloid Tipelactopeptide (ICTP) in Crevicular Gingival Fluid (FGC) of Teeth with Asymptomatic Apical Periodontitis (PAa). Student: Gianfranco Arce Salvi. Year 2012. Financing FONDECYT 1090461.
17. Levels of Vascular Endothelial Growth Factor (VEGF-A) in Periapical Lesions Consecutive Pulp Necrosis and Periodontal Ligament. Student: Magdalena Infante Figueroa. Year 2011. Financing FONDECYT 1090461.
18. Levels of Vascular Endothelial Growth Factor (VEGF) and Interleukin-1B in Gingival Crevicular Fluid (FCG) of Teeth with Asymptomatic Apical Periodontitis (PAa) Pre and Post Endodontic Treatment (2011). Student: Gustavo Pérez Serrano. Year 2011. Financing FONDECYT 1090461.
19. Levels of ICTP in Asymptomatic Apical Periodontitis and its Association with Periradicular Tissues. Student: Pamela Giralt Year 2011. Financing FONDECYT 1090461.
20. Levels of Cathepsin K in Crevicular Teeth Gingival Fluid with Asymptomatic Apical Periodontitis. Student: Loreto Espinoza. Year 2010. Financing FONDECYT 1090461.
21. Expression of Extracellular Matrix Metalloproteinase-13 (MMP-13) in Teeth with Asymptomatic Apical Periodontitis. Student: Andrea González. Year 2010. Financing FONDECYT 1090461.
Postgraduate Thesis (Master and Doctorate):
1. Polarization of macrophages in clinically symptomatic forms of apical periodontitis: Role of Lipopolysaccharide of Porphyromonas species on the expression of Toll-like receptors and their epigenetic regulation. Doctorate Program in Dental Sciences, University of Chile. Responsible tutor Student: Pablo Veloso Matta, year 2018. Financing FONDECYT 1160741. Status: Qualification exam approved.
2. Systemic inflammation and endodontic infection by Porphyromonas endodontalis in patients with asymptomatic apical periodontitis. Master's Program in Dental Sciences mention Periodontology, University of Chile. Responsible tutor Student: Patricia Huamán Chipana, year 2017. Financing FONDECYT 1120138.
3. Effects of the stimulation of human periodontal ligament fibroblasts with IL-6 on the synthesis of C-reactive protein (CRP) and proinflammatory cytokines. Master's Program in Dental Sciences mention Periodontology, University of Chile. Responsible tutor Student: Arnoldo Hernández Caldera, 2015. Funding FONDECYT 1120138.
4. Effect of stimulation with the different serotypes of Porphyromonas gingivalis and Aggregatibacter actinomycetencomitans on the activity of TCD4 + lymphocytes and bone resorption in vitro. Master's Program in Dental Sciences mention Periodontology, University of Chile. Associate tutor. Student: Student Melgar Samanta Rodríguez. Year 2014. FONDECYT 11100298.
5. Markers of bone metabolism in gingival crevicular fluid as a potential diagnostic tool for chronic inflammatory diseases of the marginal and apical periodontium. Master's Program in Odontological Sciences mention Oral Pathology. Principal tutor Student Mauricio Baeza Paredes 2014. Financing: FONDECYT 1120138.
6. Systemic inflammation in serum of patients with asymptomatic apical periodontitis. Master's Program in Odontological Sciences mention Oral Pathology. Principal tutor Student Fabián Obregón Miano year 2014. Financing: FONDECYT 1120138.
7. Effect of extracellular matrix metalloproteinases on TNF levels ?; IL-1 ?; SDF-1 / CXCL12 and VEGF in human periodontal ligament fibroblasts stimulated with hydrogen peroxide. Research work to qualify for the Master's degree in Dental Sciences. Program: Master in Cs. Dentistry mention Periodontology, University of Chile, Student: Franco Cavalla. 2013. Main tutor. Financing: FONDECYT 1090461.
8. Effect of H2O2 on the activity of alkaline phosphatase, cytokine and extracellular matrix metalloproteinase levels with osteolytic activity in human periodontal ligament fibroblasts, Magister in Cs. Dentistry mention Periodontology, University of Chile, Faculty of Dentistry. Student: Constanza Osorio 2012. Funding: FONDECYT 1090461.
9. Levels and Activity of Extracellular Matrix Metalloproteinases -2, -9, -13 and? 2-macroglobulin in teeth with Chronic Apical Periodontitis. Magister program in Cs. Dentistry mention Periodontology, University of Chile, Student (a): Verónica Mundi, 2012. Financing: FONDECYT 1090461.
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2012 Odontological Research Award
COLGATE PALMOLIVE CHILE S.A
Chile, 2012
Award for Dental Research 2012, Colgate-Palmolive Chile, Santiago Chile. December 19, 2012.
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Academic Recognition Germán Valenzuela Basterrica in Research". III Conference of Internal Reflection: Good Teaching Practices "Academic Direction
UNIVERSIDAD DE CHILE
Chile, 2012
Recognition in Dental Research awarded by academic peers
A quantitative point-of-care test for periodontal and dental peri-implant diseases |
MMP activation in diagnostics of periodontitis and systemic inflammation |
Role of IL-35, all-trans retinoic acid, and T regulatory-derived exosomes in inhibiting the tooth-supporting bone resorption during periodontitis through modulation of the Th17/Treg imbalance. |
Diseño de un screening post-natal para el diagnóstico temprano de preeclampsia basado en la detección de biomarcadores placentarios y endoteliales en fluidos orales de embarazadas |
Effect of the incorportation of copper and zinc nanoparticles into dental adhesives on their antimicrobial properties and dentinal matrix metalloproteinases activity=> from molecular basis to clinical trials |
Endodontic Pathogen-Induced Macrophage Responsiveness Profiles and their Epigenetic Regulation as Determinants for Systemic Inflammation and Treatment Response in Chronic Apical Periodontitis |
Fertility Status and Protoscolex Production in Hydatid Cysts of Echinococcus Granulosus in Ruminant Is Positively Modulated by Fasciola Hepatica Co-Infection |
Desarrollo de una plataforma de microtomografía computarizada (microCT) para el análisis de animales y especímenes experimentales con el propósito de fortalecer la investigación avanzada en ciencias odontológicas |
ROLE OF PERIODONTO-PATHOGENIC BACTERIAL SEROTYPES IN PROMOTING THE ALVEOLAR BONE RESORPTION DURING PERIODONTITIS THROUGH AN IMBALANCE OF TH1/TH 17 VERSUS TREG IMMUNE RESPONSES |
Adquisición de un microscopio electrónico de barrido y equipos auxiliares (sem-edx) para investigación avanzada en ciencias odontológicas |
Biological Plaque Control in Periodontal Diseases=> Understanding Variability of Microbiome/Immune Response and implementation of a conventional periodontal treatment combined with probiotics |
Caracterización de patrones morfológicos y biología de la anquilosis TM en humanos |
Crosstalk between local host response to endodontic infection and low-grade systemic inflammation in asymptomatic apical periodontitis=> Prospective study evaluating the effect of conservative endodontic treatment |
Characterization of oxidant status and MMP-mediated proteolysis during progression of apical periodontitis in gingival crevicular fluid=> A new tool in the search of early prognostic markers? |
The TH1 vs TREG imbalance in the pathogenesis of periodontitis=> New approach for dichotomy TH1 vs TH2 |
Caracterización del Fluido Gingival Crevicular de piezas dentarias con Lesiones Apicales y su aplicación en el monitoreo clínico |
Patrones de proteólisis asociados con la progresión de la periodontitis crónica y su relación con la actividad de la MMP-13 |