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Claudio Enrique Villota Arcos

Profesor/investigador Asociado

Universidad Bernardo O'Higgins

Santiago, Chile

mitochonrial RNAs; cancer diagnostic; Cancer; Virologia; biologia molecular, nutricion

biologia molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Bioquimico, UNIVERSIDAD DE CHILE. Chile, 2001

Profesor asistente Part Time

otra

Salud

Santiago, Chile

2005 - 2016
profesor invitado Other

universidad de los Andes

Salud

Santiago, Chile

2015 - 2018
Profesor asistente Part Time

otra

Salud

Santiago, Chile

2019 - At present

Investigador asociado Full Time

Fundacion Ciencia para la Vida

Santiago, Chile

2001 - 2019
Profesor asistente Part Time

Universidad Andres Bello

Santiago, Chile

2005 - 2017
Profesor/Investigador asociado Part Time

Universidad Bernardo O'Higgins

Santiago, Chile

2019 - At present

Participacion en programa explora

Mejor expositor joven

otra

Canada, 2005

fue reconocido como el mejor expositor joven en International Papillomavirus Society, Vancouver, Canada
Beca post-doc

otra

Chile, 2007

Fundación Instituto Milenio-UNAB me beco con beca de post-doc


Characterization of nutritional status and cardiovascular risk and its relationship with the Mediterranean diet in older adults from the metropolitan region of Chile Caracterización de estado nutricional y riesgo cardiovascular y su relación con dieta mediterránea en adultos mayores de la región metropolitana de Chile Villota, Claudio A.; Luna, Jhoavana M.; Quiroz, Sofia P.; Salvo, O. Nicole; Salvo, Nicole O.; Rodriguez, Ximena P. Article ISI SCOPUS Nutricion Clinica y Dietetica Hospitalaria (2023)
Estado nutricional y consumo de frutas, verduras, legumbres, alimentos procesados y ultraprocesados en adultos de Santiago de Chile Rodríguez, X., Villota, C., Toledo, Álvaro, Salva, R., & Cortés, V. Article Revista Española De Nutrición Humana Y Dietética (2023)
Intermittent Fasting and Reduction of Inflammatory Response in a Patient with Ulcerative Colitis Roco-Videla, Angel; Villota-Arcos, Claudio; Pino-Astorga, Carolina; Mendoza-Puga, Daniela; Bittner-Ortega, Mauricio; Corbeaux-Ascui, Tatiana Article ISI MEDICINA-LITHUANIA (2023)
Dietary intake and eating behavior in the Chilean population during the COVID-19 lockdown Rodríguez, Ximena; Pino, C.; Villota, Claudio; Riveros, Constanza; Toledo, Álvaro; Pinunuri, Raul Article SCIELO Revista chilena de nutrición (2022)
Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors Borgna, Vincenzo; Lobos-Gonzalez, Lorena; Guevara, Francisca; Landerer, Eduardo; Bendek, Maximiliano; Avila, Rodolfo; Silva, Veronica; Villota, Claudio; Araya, Mariela; Rivas, Alexis; Lopez, Constanza; Socias, Teresa; Castillo, Jorge; Alarcon, Luis; Burzio, Luis O.; Burzio, Veronica A.; Villegas, Jaime Article ISI SCOPUS JOURNAL OF CANCER (2020)
HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes Villota, Claudio; Varas-Godoy, Manuel; Jeldes, Emanuel; Campos, America; Villegas, Jaime; Borgna, Vincenzo; Burzio, Luis O.; Burzio, Veronica A. Article ISI SCOPUS AGING-US (2019)
Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors Fitzpatrick, Christopher; Bendek, Maximiliano F.; Briones, Macarena; Farfan, Nicole; Silva, Valeria A.; Nardocci, Gino; Montecino, Martin; Boland, Anne; Deleuze, Jean-Francois; Villegas, Jaime; Villota, Claudio; Silva, Veronica; Lobos-Gonzalez, Lorena; Borgna, Vincenzo; Barrey, Eric; Burzio, Luis O.; Burzio, Veronica A. Article ISI SCOPUS CELL DEATH & DISEASE (2019)
In vivo knockdown of antisense non-coding mitochondrial RNAs by a lentiviral-encoded shRNA inhibits melanoma tumor growth and lung colonization. Varas-Godoy, Manuel; Lladser, Alvaro; Farfan, Nicole; Villota, Claudio; Villegas, Jaime; Tapia, Julio C; Burzio, Luis O; Burzio, Veronica A; Valenzuela, Pablo D T Article Pigment cell & melanoma research (2018)
Cervical cancer, human papillomavirus and vaccines=> assessment of the information retrieved from general knowledge websites in Chile Lopez, C.; Krauskopf, E; Villota, C; Burzio, L.O; Villegas, J Article PUBLIC HEALTH (2017)
Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model. Borgna, Vincenzo; Villegas, Jaime; Burzio, Verónica A; Belmar, Sebastián; Araya, Mariela; Jeldes, Emanuel; Lobos-González, Lorena; Silva, Verónica; Villota, Claudio; Oliveira-Cruz, Luciana; Lopez, Constanza; Socias, Teresa; Castillo, Octavio; Burzio, Luis O Article Oncotarget (2017)
Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors. Lobos-González, Lorena; Silva, Verónica; Araya, Mariela; Restovic, Franko; Echenique, Javiera; Oliveira-Cruz, Luciana; Fitzpatrick, Christopher; Briones, Macarena; Villegas, Jaime; Villota, Claudio; Vidaurre, Soledad; Borgna, Vincenzo; Socias, Miguel; Valenzuela, Sebastián; Lopez, Constanza; Socias, Teresa; Varas, Manuel; Díaz, Jorge; Burzio, Luis O; Burzio, Verónica A Article Oncotarget (2016)
Down-regulation of the Antisense Mitochondrial Non-coding RNAs (ncRNAs) Is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy Vidaurre S.; Fitzpatrick, C; Burzio, VA; Briones, M.; Villota, C; Villegas, J; Echeñique J.; Oliveira-Cruz, L; Araya M.; Borgna, V; Socias, T; López C.; Ávila R.; Burzio, LO Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer Rivas, A; Burzio V; Landerer, E.; Borgna, V; Gatica, S; Ávila R.; López C.; Villota, C; De La Fuente R.; Echeñique J.; Burzio L.O.; Villegas, J Article ISI SCOPUS BMC Urology (2012)
Expression of Mitochondrial Non-coding RNAs (ncRNAs) Is Modulated by High Risk Human Papillomavirus (HPV) Oncogenes Villota, C; Campos A.; Vidaurre S.; Oliveira-Cruz, L; Boccardo, E; Burzio, V.A.; Varas, M; Villegas, J; Villa L.L.; Valenzuela P.D.T.; Socias, M; Roberts, S.; Burzio L.O. Article ISI SCOPUS Journal of Biological Chemistry (2012)
Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells Landerer, E.; Villegas, J; Burzio, VA; Oliveira L.; Villota, C; López C.; Restovic, F; Martínez R.; Castillo O.; Burzio, LO Article ISI SCOPUS Cellular Oncology (2011)
Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells Burzio, VA; Villota, C; Villegas, J; Landerer, E.; Boccardo, E; Villa, LL; Martínez R.; López C.; Gaete, F; Toro V.; Rodríguez X; Burzio, LO Article ISI SCOPUS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Expression of a novel non-coding mitochondrial RNA in human proliferating cells Villegas, J; Burzio V; Villota, C; Landerer, E.; Martínez R.; Santander, M; Pinto, R; Vera, MI; Boccardo, E; Villa, LL; Burzio, LO Article ISI NUCLEIC ACIDS RESEARCH (2007)
Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in seronegative tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) patients Ramírez E.; Fernandez, J; Cartier, L; Villota, C; Rios M. Article ISI SCOPUS VIRUS RESEARCH (2003)
Genetic characterization and phylogeny of human T-cell lymphotropic virus type I from Chile Ramírez E.; Cartier, L; Villota, C; Fernandez, J Article ISI SCOPUS VIRUS RESEARCH (2002)


Mitochondrial non-coding RNAs as therapeutic target in cervical cancer Ávila R.; Farfan, N; Lobos, L; Silva, V.; Villota, C; Burzio, LO; Villegas, J Abstract ISI FEBS JOURNAL (2014)
Non Coding Mitochondrial RNAs as Novel Teragnostic Molecular Tool in Cervix Cancer Villegas, J; Ávila R.; Dadlani, K; Socias, M; Zapata L.; Villota, C; Burzio V; Oliveira-Cruz, L; Bustamante, E; Burzio, LO Abstract ISI EUROPEAN JOURNAL OF CANCER (2012)
The antisense non-coding mitochondrial RNA as a molecular therapeutic target for a murine model of melanoma Burzio V; Vidaurre S.; Villegas, J; Villota, C; Echeñique J.; Burzio, LO Abstract FEBS JOURNAL (2011)
Sense and antisense noncoding mitochrondrial RNA differentiate normal from tumor cells Landerer, E.; Villegas, J; Burzio V; Villa, L.; Boccardo, E; Socias, M; Gaete, F; Toro V.; Burzio, L; Villota, C Abstract ISI ACTA CYTOLOGICA (2007)


Long Noncoding mitochondrial RNAs (LncmtRNAs) as target for cancer therapy Villegas J, Burzio VA, Borgna V, Bobos L, Araya M, Guevara F, Villota C, Burzio LO BookSection (2018)
Horizons in cancer research. Vol 65: Non-coding mitochondrial RNAs in gynecoligal and urinary malignancies: Universal targets for development of an efficient therapy? V. Borgna, L. lobos-Gonzalez, V. Burzio, M. Araya, R. Avila, E. Jeldes, V. Silva, M. Briones, T.Socias, F. Guevara, C. Lopez, C. Villota, E. Bustamante, M. bendex, C. Fitzpatrick, LO Burzio and J. Villegas BookSection (2017)


Human papillomavirus and non-coding RNAs: From basics to diagnostic Villota, C; Cifuentes-Muñoz N; Burzio L.O. BookWhole SCOPUS Materials Science and Technology Conference and Exhibition 2014, MS and T 2014 (2013)


Validacion de terapia antisentido para cáncer cervicouterino in vivo FONDECYT (D10E1090) Proyecto 2017-2018 Subdirector(a)
Determinación de la región de E2 del Virus del Papiloma Humano de alto riesgo responsable de inducir la baja expresión del RNA mitocondrial no codificante Antisentido Universidad Andres Bello (DI-100-12/R) Proyecto 2012-2013 Inv. Principal
Desarrollo de una terapia selectiva contra cáncer cervicouterino FONDAP (D10I1090) Proyecto 2011-2014 Coinvestigador(a)
Determinación de la expresión de los RNAs mitocondriales no codificantes durante la transformación celular inducida por el virus del Papiloma Humano tipo 16 y detección precoz del cáncer de cuello de útero Universidad Andres Bello (DI-100-09/R) Proyecto 2009-2011 Inv. Principal
Determination of the expression of non-coding mitochondrial RNAs during cell transformation induced by HPV-16 and early detection of cervical cancer FONDECYT (11090060) Proyecto 2009-2012 Inv. Principal