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Jordi Olloquequi González

Profesor Titular

UNIVERSIDAD AUTONOMA DE CHILE

Talca, Chile

Patología pulmonar; Inflamación; Inmunología; Neurodegeneración

Licenciado en Biología. Especialidad Biología Sanitaria, UNIVERSIDAD DE BARCELONA. España, 2006
DEA. Programa de doctorado de FISIOLOGIA, UNIVERSIDAD DE BARCELONA. España, 2008
Biología Celular, Universidad de Barcelona. España, 2010

Profesor Titular - Académico Docente Investigador (ADI) Full Time

Universidad Autónoma de Chile

Facultad de Ciencias de la Salud

Talca, Chile

2014 - A la fecha
Profesor Asociado Part Time

Universidad de Barcelona

Facultad de Biología

Barcelona, España

2011 - 2014

Investigador Júnior

Fundación Catalana de Pneumología (FUCAP)

España

2006 - 2007
Investigador Pre-Doctoral

Departamento de Biología Celular, Facultad de Biología, Universidad de Barcelona

España

2007 - 2010
Investigador Post-Doctoral

Departamento de Biología Celular, Facultad de Biología, Universidad de Barcelona

España

2011 - 2014
Profesor Asociado

Universidad de Barcelona

España

2011 - 2014


A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet Pont, Caterina; Munoz-Torrero, Diego Article ISI CELL AND BIOSCIENCE (2023)
Decreased Expression of EC-SOD and Fibulin-5 in Alveolar Walls of Lungs From COPD Patients Martin-Satue, Mireia; Texido, Laura Article ISI ARCHIVOS DE BRONCONEUMOLOGIA (2022)
Identification of Circulating lncRNAs Associated with Gallbladder Cancer Risk by Tissue-Based Preselection, Cis-eQTL Validation, and Analysis of Association with Genotype-Based Expression Blandino, Alice; Morales, Erik; Cortes, Analia; Ortega, Alejandro; Gabler, Fernando; Spencer, Loreto; Almau, Mauricio; Fernandez, Plinio; Bortolini, Maria Catira; Linares, Andres Ruiz Article ISI CANCERS (2022)
Impact of New Drugs for Therapeutic Intervention in Alzheimer's Disease Espinosa, Triana; Gudino-Cabrera, Graciela Article ISI FRONTIERS IN BIOSCIENCE-LANDMARK (2022)
Is adherence to the Mediterranean diet associated with healthy habits and physical fitness? A systematic review and meta-analysis including 565 421 youths Ezzatvar, Yasmin; Francisco Lopez-Gil, Jose Article ISI BRITISH JOURNAL OF NUTRITION (2022)
JNK1 and JNK3: divergent functions in hippocampal metabolic-cognitive function Cantero, Jose Luis Article ISI MOLECULAR MEDICINE (2022)
Peroxisomal Proliferator-Activated Receptor beta/delta Deficiency Induces Cognitive Alterations Article ISI FRONTIERS IN PHARMACOLOGY (2022)
Pharmacogenetic Variation and Its Clinical Relevance in a Latin American Rural Population Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Polymorphisms in the FRMD4A Gene Are Associated With Chronic Obstructive Pulmonary Disease Susceptibility in a Latin American Population Julia, Raul F. Article ISI ARCHIVOS DE BRONCONEUMOLOGIA (2022)
Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders Fortuna, Ana Article ISI BIOMEDICINE & PHARMACOTHERAPY (2022)
Specific miRNA Profile in Chronic Obstructive Pulmonary Disease Related to Biomass Smoke Exposure III, Howard Dean Hosgood Article ISI ARCHIVOS DE BRONCONEUMOLOGIA (2022)
Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer's disease in metabolically stressed APPswe/PS1dE9 mice Carrasco, Marina Article ISI CELL AND BIOSCIENCE (2021)
Dual Mkk4 and Mkk7 Gene Deletion in Adult Mouse Causes an Impairment of Hippocampal Immature Granule Cells Caruana, Pablo; Steele, Luke; Leighton, Kyra-Mae Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Gallstones, Body Mass Index, C-Reactive Protein, and Gallbladder Cancer: Mendelian Randomization Analysis of Chilean and European Genotype Data Ponce, Carol Barahona; Toro, Gonzalo; Morales, Erik; Ortega, Alejandro; Bertran, Maria Enriqueta; Gabler, Fernando; Spencer, Loreto; Guajardo, Macarena Fuentes Article ISI HEPATOLOGY (2021)
Is device-measured vigorous physical activity associated with health-related outcomes in children and adolescents? A systematic review and meta-analysis Article ISI JOURNAL OF SPORT AND HEALTH SCIENCE (2021)
Metformin a Potential Pharmacological Strategy in Late Onset Alzheimer's Disease Treatment Poor, Saghar Rabiei; Manzine, Patricia Regina Article ISI PHARMACEUTICALS (2021)
Pharmacological Strategies to Improve Dendritic Spines in Alzheimer's Disease Article ISI JOURNAL OF ALZHEIMERS DISEASE (2021)
The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies Rayatpour, Atefeh; Farhangi, Sahar; Urena, Jesus; Javan, Mohammad Article ISI PHARMACEUTICALS (2021)
ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans Baez Benavides, Pablo F.; de Toro, Gonzalo; Retamales, Javier; Morales, Erik; Loader, Denisse; Rivera, María Teresa; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Gabler, Fernando; et al. Article ISI SCOPUS Cancer Epidemiology (2020)
Amerindian Ancestry Influences Genetic Susceptibility to Chronic Obstructive Pulmonary Disease Dean Hosgood III, H.; Agust, Alvar Article ISI JOURNAL OF PERSONALIZED MEDICINE (2020)
Association analysis in a Latin American population revealed ethnic differences in rheumatoid arthritis-associated SNPs in Caucasian and Asian populations Article WOS SCIENTIFIC REPORTS (2020)
Association between Exercise-Induced Changes in Cardiorespiratory Fitness and Adiposity among Overweight and Obese Youth: A Meta-Analysis and Meta-Regression Analysis Faigenbaum, Avery Article ISI CHILDREN-BASEL (2020)
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia Article ISI SCOPUS (2020)
COVID-19 Susceptibility in chronic obstructive pulmonary disease Article ISI EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2020)
Environmental health literacy and household air pollution-associated symptoms in Kenya: a cross-sectional study Raufman, Jill; Lounsbury, David W.; Mwangi, Esther Wairimu Article ISI ENVIRONMENTAL HEALTH (2020)
Epigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice Article ISI SCOPUS MOLECULAR NEUROBIOLOGY (2020)
Excitotoxicity as a Target Against Neurodegenerative Processes Binvignat, Octavio Article ISI CURRENT PHARMACEUTICAL DESIGN (2020)
Healthy Lifestyle Behaviors and Their Association with Self-Regulation in Chilean Children Fernandez-Vergara, Omar Article ISI International #Journal of Environmental Research and Public Health (2020)
HLA-A, B, C and DRB1 alleles in a Chilean population from Talca Article ISI SCOPUS HLA (2020)
HLA-DRB1 ALLELES ARE ASSOCIATED WITH COPD IN A LATIN AMERICAN ADMIXED POPULATION Silva, Rafael Article WoS ARCHIVOS DE BRONCONEUMOLOGIA (2020)
HLA-DRB107:01 and08:02 Alleles Confer a Protective Effect Against ACPA-Positive Rheumatoid Arthritis in a Latin American Admixed Population Pinochet, Carmen Article ISI BIOLOGY-BASEL (2020)
Involvement of JNK1 in Neuronal Polarization During Brain Development Parcerisas, Antoni; Etchetto, Miren Article ISI CELLS (2020)
PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile Hosgood, H. Dean, III; Bermejo, Justo Lorenzo; Valdivia, Gonzalo; Silva, Rafael S. Article ISI RESPIRATION (2020)
The preclinical discovery and development of opicapone for the treatment of Parkinson's disease Article ISI EXPERT OPINION ON DRUG DISCOVERY (2020)
c-Jun N-terminal Kinase 1 ablation protects against metabolic-induced hippocampal cognitive impairments Article ISI SCOPUS JOURNAL OF MOLECULAR MEDICINE-JMM (2019)
Deficient pulmonary IFN-beta expression in COPD patients GarcÃa-Valero J.; MartÃn-SatuÃ© M.; TexidÃ³ L.; Sancho J.F. Article ISI SCOPUS PLOS ONE (2019)
JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy Landa J.; Rabaza M. Article ISI SCOPUS MOLECULAR NEUROBIOLOGY (2019)
Role of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model Eritja Ã€.; LÃ³pez B.M.; VÃ¡zquez-Carrera M. Article ISI SCOPUS JOURNAL OF NEUROCHEMISTRY (2019)
Triple GLP-1/GIP/glucagon receptor agonists, a potential novel treatment strategy in Alzheimer's disease Manzine, PR; Sureda, FX; Bullo, M Article ISI SCOPUS EXPERT OPINION ON INVESTIGATIONAL DRUGS (2019)
Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis García-Hermoso, Antonio; Ramírez-Vélez, Robinson; Izquierdo, Mikel Article ISI SCOPUS EXPERIMENTAL GERONTOLOGY (2018)
Comparative analysis of COPD associated with tobacco smoking, biomass smoke exposure or both Olloquequi, J; Jaime, S; Parra, V; Cornejo-Cordova, E; Valdivia, G; Agusti, A; Silva, R Article RESPIRATORY RESEARCH (2018)
Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimers Disease Abad, S.; Pedros, I.; Busquets, O; Pallas, M. Article ISI MOLECULAR NEUROBIOLOGY (2018)
Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications Cornejo-Córdova, Elizabeth; Verdaguer, Ester; Soriano, Francesc X; Auladell, Carme; Camins, Antoni Article ISI SCOPUS JOURNAL OF PSYCHOPHARMACOLOGY (2018)
Memantine for the Treatment of Dementia: A Review on its Current and Future Applications Folch, Jaume; Busquets, Oriol; Ettcheto, Miren; Sánchez-López, Elena; Castro-Torres, Ruben Dario; Verdaguer, Ester; Garcia, Maria Luisa; Beas-Zarate, Carlos; Pelegri, Carme; Vilaplana, Jordi; et al. Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2018)
The Implication of the Brain Insulin Receptor in Late Onset Alzheimers Disease Dementia Folch, Jaume; Ettcheto, Miren; Busquets, Oriol; Sánchez-López, Elena; Castro-Torres, Rubén; Verdaguer, Ester; Manzine, Patricia; Poor, Saghar; Beas-Zarate, Carlos; Auladell, Carme; et al. Article ISI SCOPUS PHARMACEUTICALS (2018)
Associations between the duration of active commuting to school and academic achievement in rural Chilean adolescents Ramírez-Vélez, R. Article ISI SCOPUS Environmental Health and Preventive Medicine (2017)
Biomass smoke as a risk factor for COPD: effects on innate immunity Olloquequi, J; Silva, RO Article ISI Innate Immunity (2017)
Caracterización general de los pacientes con EPOC de la Región del Maule=> resultados preliminares del estudio MaulEPOC Jordi Olloquequi G., Sergio Jaime J.; Viviana Parra R., Cintia Muñoz V.; Alejandra Muñoz G., Fabiola Lastra F.; Cristián Vergara E., Carolina Lara L.; Karen Czischke L., Pilar García N.; Elizabeth Cornejo C.,Rafael Silva O. Article Revista chilena de enfermedades respiratorias (2017)
Cardiorespiratory Fitness and Muscular Strength as Mediators of the Influence of Fatness on Academic Achievement Esteban-Cornejo I. Article ISI SCOPUS JOURNAL OF PEDIATRICS (2017)
Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways Pons L. Article ISI SCOPUS REDOX BIOLOGY (2017)
Effects of Exercise on Carotid Arterial Wall Thickness in Obese Pediatric Populations: A Meta-Analysis of Randomized Controlled Trials Article ISI SCOPUS CHILDHOOD OBESITY (2017)
Effects of Exercise on Carotid Arterial Wall Thickness in Obese Pediatric Populations: A Meta-Analysis of Randomized Controlled Trials. González-Ruiz K; Triana-Reina, HR; Olloquequi, J Article ISI Frontiers in Bioscience (Landmark Edition). (2017)
Neuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms Castro-Torres R.D. Article SCOPUS Molecular Neurobiology (2017)
Role of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration Article ISI SCOPUS Frontiers in Bioscience - Landmark (2017)
Role of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration. Auladell, C; de Lemos, L; Verdaguer, E; Ettcheto, M; Busquets, O; Lazarowski A; Olloquequi, J; Folch, J; Camins, A Article ISI Frontiers in Bioscience (Landmark Edition). (2017)
Biomass smoke as a risk factor for chronic obstructive pulmonary disease: effects on innate immunity. Olloquequi J, Sivla O R Article Innate Immunity (2016)
Current research therapeutic strategies for Alzheimer’s Disease treatment. Folch, J; Petrov, D; Abat S; Olloquequi, J; Beas- Zárate C; Auladell, C; Camins, A Article ISI Experimental gerontology (2016)
Cellular effectors of the inflammatory response in chronic obstructive pulmonary disease (COPD) Silva R.; Montes JF; Garcia-Valero, J; Olloquequi, J Article ISI REVISTA MEDICA DE CHILE (2015)
Cellular effectors of the inflammatory response in chronic obstructive pulmonary disease (COPD) [Efectores celulares de la respuesta inflamatoria en la enfermedad pulmonar obstructiva crónica] Silva O R.; Olloquequi, J Article SCOPUS Revista Medica de Chile (2015)
Masitinib for the treatment of mild to moderate Alzheimer’s disease. Folch, J; Petrov, D; Ettcheto, M; Abat S; Lazarowski A; Marin M.; Olloquequi, J; Auladell, C; Camins, A Article ISI Expert Review of Neurotherapeutics (2015)
Pathogenic Mechanisms in Chronic Obstructive Pulmonary Disease Due to Biomass Smoke Exposure Silva, Rafael Article WOS ARCHIVOS DE BRONCONEUMOLOGIA (2015)
Pathogenic Mechanisms in Chronic Obstructive Pulmonary Disease Due to Biomass Smoke Exposure. Silva, Rafael Article ISI (2015)
Review of the advances in the treatment for Alzheimer disease: Strategies for combating β-amyloid protein. Folch, J; Ettcheto, M; Petrov, D; Abat S; Marin M.; Olloquequi, J; Camins, A Article ISI Neurologia (2015)
Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis Verdaguer, E; Brox S; Petrov, D; Olloquequi, J; Romero R.; De Lemos ML; Camins, A; Auladell, C Article ISI Experimental gerontology (2015)
Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death Martorell-Riera, A; Segarra-Mondejar, M; Munoz, JP; Ginet V; Olloquequi, J; Perez-Clausell, J; Palacin, M; Reina M.; Puyal J; Zorzano, A; et al. Article ISI SCOPUS EMBO JOURNAL (2014)
Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death. Ginet V; Olloquequi, J; Pérez Clausell J; Reina M.; Puyal J; Zorzano, A; Soriano FX Article ISI EMBO JOURNAL (2014)
Lung CD57+ cell density is increased in very severe COPD. Olloquequi, J; Montero MA; Ferrer, J; Montes JF Article ISI HISTOLOGY AND HISTOPATHOLOGY (2012)
Significant increase of CD57+ cells in pulmonary lymphoid follicles of COPD patients. Olloquequi, J; Montes JF; Prats, A.; Montero MA; Ferrer, J Article ISI EUROPEAN RESPIRATORY JOURNAL (2011)
Differential lymphocyte infiltration in small airways and lung parenchyma in COPD patients. Olloquequi, J; Ferrer, J; Montes JF; Montero MA Article ISI RESPIRATORY MEDICINE (2010)


Modulación de la vía del receptor de insulina hipocampal como estrategia terapéutica para el tratamiento de la pérdida cognitiva. Ministerio de Economía, Industria y Competividad del Gobierno de España (SAF2017-84283-R) Proyecto 2018-2020 Investigador(a)
ALTERACIONES DEL METABOLISMO GLUCO-LIPIDICO Y DESARROLLO DE LA DEMENCIA DE ALZHEIMER Instituto de Salud Carlos Tercero (PI2016/01) Proyecto 2016-2018 Investigador(a)
Analysis of inflammatory and autoimmunity-related genes in Chilean individuals with Chronic Obstructive Pulmonary Disease FONDECYT (11150022) Proyecto 2015-2018 Inv. Responsable
ANALYSIS OF INFLAMMATORY AND AUTOIMMUNITY-RELATED GENES IN CHILEAN INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE Jordi Olloquequi Proyecto (2015)
IMPLICACIÓN DE LA VIA DE JNK EN EL CONTROL DE PROTEÍNAS ASOCIADAS A MICROTÚBULOS Y DE PROTEÍNAS DE UNIÓN AL CALCIO EN UN MODELO MURINO DE EPILEPSIA Becas Iberoamérica Jóvenes Investigadores. Santander Universidades. (BSIJ201520) Proyecto 2015-2016 Inv. Principal
Does COPD severety correlates with inflammatory activity? GlaxoSmithKline,S.A (GS089923) Proyecto 2010-2012 Postdoctorado
Study and manipulation of Mfn2 gene expression in excitotoxicity La Marató TV3 (111210) Proyecto 2010-2012 Investigador(a)
¿Existe una correlación entre la actividad inflamatoria y la gravedad de la EPOC? Fondo de Investigación Sanitaria - Instituto de Salud Carlos III (PI040635) Proyecto 2005-2007 Investigador(a)


Role of c-Jun N-Terminal Kinases (JNKs) in Epilepsy and Metabolic Cognitive Impairment Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Experimental models for aging and their potential for novel drug discovery SÃ¡nchez-LÃ³pez E. Review ISI SCOPUS (2018)
Review of the advances in treatment for Alzheimer disease: Strategies for combating beta-amyloid protein Folch, J; Ettcheto, M; Petrov, D; Abad, S.; Pedros, I.; Olloquequi, J; Camins, A Review ISI SCOPUS NEUROLOGIA (2018)
Biomass smoke as a risk factor for chronic obstructive pulmonary disease: effects on innate immunity Olloquequi, J; Rafael Silva O. Review ISI SCOPUS INNATE IMMUNITY (2016)
Current Research Therapeutic Strategies for Alzheimer's Disease Treatment Folch, J; Petrov, D; Ettcheto, M; Abad, S.; Sanchez-Lopez, E; Garcia, ML; Olloquequi, J; Beas-Zarate, C; Auladell, C; Camins, A Review ISI SCOPUS NEURAL PLASTICITY (2016)
Efectores celulares de la respuesta inflamatoria en la enfermedad pulmonar obstructiva crónica Rafael Silva O.; Juan F Montes; José García-Valero; Jordi Olloquequi Review SCIELO REVISTA MEDICA DE CHILE (2015)
Masitinib for the treatment of mild to moderate Alzheimer's disease Folch, J; Petrov, D; Ettcheto, M; Pedros, I.; Abad, S.; Beas-Zarate, C; Lazarowski A; Marin M.; Olloquequi, J; Auladell, C; et al. Review ISI SCOPUS Expert Review of Neurotherapeutics (2015)