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Natalia Andrea Salvadores Bersezio

Profesora Asistente

Universidad Mayor de Chile

Temuco, Chile

Molecular basis of neurodegenerative diseases; Early diagnosis of neurodegenerative diseases; Alzheimer´s disease; Parkinson´s disease.

Licenciado en Bioquímica, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2008
Biomedical Sciences, UNIVERSITY OF EDINBURGH. Reino Unido, 2016
Bioquímico, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2008

Profesora Asistente Full Time

UNIVERSIDAD MAYOR

Facultad de Ciencias

Temuco, Chile

2022 - A la fecha

Asistente de investigación Full Time

Aquagestión S.A.

Puerto Montt, Chile

2007 - 2007
Research Associate Full Time

University of Texas Medical Branch

Galveston, Estados Unidos

2008 - 2008
Research Associate Full Time

University of Texas Health Science Center

Houston, Estados Unidos

2009 - 2010
investigador postdoctoral Full Time

Universidad Mayor

Santiago, Chile

2016 - 2021

AXA research fund

UNIVERSITY OF EDINBURGH

Francia, 2011

Financiamiento por tres años para realización de doctorado.
Becas Chile, CONICYT

UNIVERSITY OF EDINBURGH

Chile, 2011

Beca para realización de doctorado en el extranjero
Scottish Overseas Research students Award Scheme

UNIVERSITY OF EDINBURGH

Reino Unido, 2011

Beca para realización de doctorado
Charles Darwin Postgraduate Research Scholarship

UNIVERSITY OF EDINBURGH

Reino Unido, 2011

Beca para realización de doctorado
Fondecyt Postdoctorado

UNIVERSIDAD MAYOR

Chile, 2018

Financiamiento por tres años para realización de proyecto postdoctoral


A beta oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease Salvadores, Natalia; Moreno-Gonzalez, Ines; Gamez, Nazaret; Quiroz, Gabriel; Vegas-Gomez, Laura; Escandon, Marcela; Jimenez, Sebastian; Vitorica, Javier; Gutierrez, Antonia; Soto, Claudio; Court, Felipe A. Article ISI ACTA NEUROPATHOLOGICA COMMUNICATIONS (2022)
Editorial: Novel mechanisms involved in aging and neurodegeneration: Seeking potential therapeutic targets for neurodegenerative diseases Sanhueza, Mario; Manso, Yasmina; Soto, Claudio; Salvadores, Natalia Article ISI FRONTIERS IN AGING NEUROSCIENCE (2022)
Axonal Degeneration in AD: The Contribution of A beta and Tau Salvadores, Natalia; Geronimo-Olvera, Cristian; Court, Felipe A. Article ISI FRONTIERS IN AGING NEUROSCIENCE (2020)
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease Onate, Maritza; Catenaccio, Alejandra; Salvadores, Natalia; Saquel, Cristian; Martinez, Alexis; Moreno-Gonzalez, Ines; Gamez, Nazaret; Soto, Paulina; Soto, Claudio.; Hetz, Claudio; Court, Felipe A. Article ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2020)
The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade? Salvadores, Natalia; Court, Felipe A. Article ISI EXPERT OPINION ON THERAPEUTIC TARGETS (2020)
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis HernÃ¡ndez D.E.; Salvadores N.A.; Moya-Alvarado G.; CatalÃ¡n R.J.; Bronfman F.C.; Court, F. A. Article ISI SCOPUS Journal of Cell Science (2018)
Chronic cerebral hypoperfusion alters amyloid-Î² peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice. Salvadores, Natalia; Searcy, James L; Holland, Philip R; Horsburgh, Karen Article Clinical science (London, England => 1979) (2017)
Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism. Mukherjee, Abhisek; Morales-Scheihing, Diego; Salvadores, Natalia; Moreno-Gonzalez, Ines; Gonzalez, Cesar; Taylor-Presse, Kathleen; Mendez, Nicolas; Shahnawaz, Mohammad; Gaber, A Osama; Sabek, Omaima M; Fraga, Daniel W; Soto, Claudio Article The Journal of experimental medicine (2017)
Molecular interaction between type 2 diabetes and Alzheimer's disease through cross-seeding of protein misfolding Moreno-Gonzalez, I; Edwards III, G; Salvadores, N; Shahnawaz, M; diaz-espinoza, R; Soto, C Article ISI SCOPUS MOLECULAR PSYCHIATRY (2017)
Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease Holland, Philip R.; Searcy, James L.; Salvadores, Natalia; Scullion, Gillian; Chen, Guiquan; Lawson, Greig; Scott, Fiona; Bastin, Mark E.; Ihara, Masafumi; Kalaria, Rajesh; Wood, Emma R.; Smith, Colin; Wardlaw, Joanna M.; Horsburgh, Karen Article ISI JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
Detection of misfolded Abeta oligomers for sensitive biochemical diagnosis of Alzheimer's disease Salvadores, Natalia; Shahnawaz, Mohammad; Scarpini, Elio; Tagliavini, Fabrizio; Soto, Claudio Article Cell Reports (2014)
Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice Searcy, James L.; Le Bihan, Thierry; Salvadores, Natalia; McCulloch, James; Horsburgh, Karen Article ISI PLOS ONE (2014)
Neuronal cytoskeletal dynamic modification and neurodegeneration induced by infection with herpes simplex virus type 1 Zambrano, A; Solís L.; Salvadores N.; Cortes, M; Lerchundi R.; Otth, C Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2008)
Axonal degeneration during aging and its functional role in neurodegenerative disorders Salvadores, Natalia; Sanhueza, Mario; Manque, Patricio; Court, Felipe Article Frontiers in Neurosciences (0)


Evaluación de muestras no invasivas para el diagnóstico de la enfermedad de Parkinson usando la técnica RT-QuIC en pacientes chilenos. Salvadores, Natalia Proyecto (2022)
Center for Geroscience, Brain Health and Metabolism FONDAP (15150012) Proyecto 2015-2020 Postdoctorado
Amyloid-beta and chronic cerebral hypoperfusion in the early pathogenesis of Alzheimer’s disease PFCHA (72120282) Proyecto 2011-2015 Tesista
Pathogenesis of Alzheimer’s disease=> The link between aging, vascular disease and cognitive decline AXA Research Fund (CT-0588) Proyecto 2011-2013 Inv. Responsable
Alteración del citoesqueleto neuronal inducida por la infección in vitro del virus herpes simple tipo I Fundación Andes (C-14060/5) Proyecto 2006-2007 Tesista


Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders Salvadores N.; Sanhueza M.; Manque P.; Court F.A. Review ISI SCOPUS FRONTIERS IN NEUROSCIENCE (2017)