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Patricio Alejandro Rojas Montecinos

Assistant Professor

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Cellular Neurophysiology; Ion Channel Biophysics; GABAA Channels and Chloride Dynamics; Neurociencia; FisiologÃa; BiofÃsica; Estructura y funciÃ³n de canales TRP; RegulaciÃ³n de canales iÃ³nicos; FisiologÃa sensorial

Cellular and Molecular Biology and Neuroscience, UNIVERSIDAD DE CHILE. Chile, 2005
Biology, UNIVERSIDAD DE CHILE. Chile, 1996

Assistant Professor Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Facultad de Quimica y Biologia

Santiago, Chile

2010 - At present
Researcher Part Time

Centro de Estudios de Zonas Aridas (CEAZA)

La Serena, Chile

2009 - Not Available

Post-Doctoral fellow Dpt Anatomy and Neurobiology Full Time

Washington University in St. Louis

St Louis, Estados Unidos

2005 - 2008
Post-Doctoral fellow Dpt Psychiatry Full Time

Washington University in St. Louis

Saint Louis, Estados Unidos

2008 - 2009

- Marilyn Gatica. Thesis for Mathematical Engineering, Universidad de Santiago de Chile
- Javier Palma. Thesis for Electrical Engineering, Universidad de Santiago de Chile
- Enrique Lorca. Thesis for Biochemist, Universidad de Santiago de Chile
- Marcelo Lara. Thesis for Biotechnology, Universidad de Santiago de Chile


Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory Moraga-Amaro, R; GONZALEZ, H; Ugalde, V.; Donoso-Ramos, JP; Quintana-Donoso, D; Lara, M; Morales, B; Rojas P.; Pacheco R.; Stehberg, J Article ISI SCOPUS NEUROPHARMACOLOGY (2016)
MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression Benoist, M; Palenzuela, R; Rozas C.; Rojas P.; Tortosa E.; Morales, B; Gonzalez-Billault, C; Avila J.; Esteban, JA Article ISI SCOPUS EMBO Journal (2013)
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability Fritz, E.; Izaurieta, P; Weiss, A; Mir, FR; Rojas P.; González D; Rojas F.; Brown, RH; Madrid R.; van Zundert, B Article ISI SCOPUS Journal of Neurophysiology (2013)
Acutely applied MDMA enhances long-term potentiation in rat hippocampus involving D1/D5 and 5-HT2 receptors through a polysynaptic mechanism Rozas C.; Loyola S; Ugarte, G.; Zeise M.L.; Reyes-Parada, M; Pancetti F.; Rojas P.; Morales, B Article ISI SCOPUS EUROPEAN NEUROPSYCHOPHARMACOLOGY (2012)
K+ Channels: Function-Structural Overview González C; Baez-Nieto, D; Valencia I.; Oyarzun, I; Rojas P.; Naranjo, D; Latorre R. Article ISI SCOPUS Comprehensive Physiology (2012)
Differential Effects of Axon Initial Segment and Somatodendritic GABA(A) Receptors on Excitability Measures in Rat Dentate Granule Neurons Rojas P.; Akrouh A.; Eisenman, LN; Mennerick S. Article ISI SCOPUS Journal of Neurophysiology (2011)
Na+-activated K+ channels express a large delayed outward current in neurons during normal physiology Budelli G.; Hage T.A.; WeiÃŸ A.; Rojas P.; Ivy Jong Y.-J.; O'Malley K.; Salkoff, L Article SCOPUS NATURE NEUROSCIENCE (2009)
Structural determinants for functional coupling between the ? and ? subunits in the Ca2+-activated K+ (BK) channel Orio, P; Torres Y.; Rojas P.; Carvacho I.; Latorre R.; Garcia, M. L.; Toro, L.; Valverde M.A. Article JOURNAL OF GENERAL PHYSIOLOGY (2006)
Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel Orio, P; Torres Y.; Rojas P.; Carvacho I.; Garcia, ML; Toro, L.; Valverde, MA; Latorre R. Article ISI SCOPUS JOURNAL OF GENERAL PHYSIOLOGY (2006)
Dissection of K+ currents in Caenorhabditis elegans muscle cells by genetics and RNA interference Santi, CM; Yuan, A; Fawcett, G; Wang, ZW; Butler A.; *Nonet ML; WeiÃŸ A.; Rojas P.; Salkoff, L Article ISI SCOPUS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
New disguises for an old channel: MaxiK channel ?-subunits Orio, P; Rojas P.; Ferreira, G; Latorre R. Article SCOPUS NEWS IN PHYSIOLOGICAL SCIENCES (2002)
New disguises for an old channel: MaxiK channel beta-subunits Orio, P; Rojas P.; Ferreira, G; Latorre R. Article ISI NEWS IN PHYSIOLOGICAL SCIENCES (2002)
Kinetic characterization of calcium uptake by the rat liver Golgi apparatus Rojas P.; Surroca, A; Orellana, A; Wolff, D Article ISI SCOPUS CELL BIOLOGY INTERNATIONAL (2000)
Acute activation of Maxi-K channels (hSlo) by estradiol binding to the ? subunit Valverde M.A.; Rojas P.; Amigo, J; Cosmelli, D; Orio, P; Bahamonde M.I.; Vergara C.; Latorre R.; Mann G.E. Article SCIENCE (1999)


Molecular basis of BK modulation by beta subunits and channel activation by estrogens. Rojas P.; Orio, P; Carvacho I.; Torres Y.; Brauchi, S.; Garcia, ML; Toro, L.; Valverde, MA; Latorre R. Abstract BIOPHYSICAL JOURNAL (2003)
Domains of beta subunit involved in modulation of MaxiK channel modulation Rojas P.; Orio, P; Toro, L.; Garcia, ML; Latorre R. Abstract BIOPHYSICAL JOURNAL (2002)
MaxiK channel activation by estradiol and tamoxifen: Role of the extracellular domain of the beta 1-subunit Orio, P; Rojas P.; Toro, L.; Latorre R. Abstract BIOPHYSICAL JOURNAL (2002)


Signal transduction-dependent channels Latorre R.; González C; Rojas P. BookWhole SCOPUS Neuroscience in the 21st Century: From Basic to Clinical (2013)


The epithelial sodium channel delta-subunit: new notes for an old song Giraldez T.; Rojas P.; Jou J.; Flores C.; de la Rosa D.A. Review ISI SCOPUS American Journal of Physiology - Renal Physiology (2012)