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Felipe Esteban Jimenez Aspee

Profesor Conferenciante

UNIVERSIDAD DE TALCA

Talca, Chile

Líneas de Investigación


Isolation and structural elucidation of bioactive compounds; Pharmacology of bioactive products; Bioactive compounds from food and medicinal plants

Educación

  •  Doctor en Ciencias, mención Investigación y Desarrollo de Productos Bioactivos, UNIVERSIDAD DE TALCA. Chile, 2016

Experiencia Académica

  •   Profesor Conferenciante Full Time

    UNIVERSIDAD DE TALCA

    2016 - At present

Experiencia Profesional

  •   Ayudante de Cátedra

    Universidad de Valparaiso

    Chile

    2008 - 2011

  •   Ayudante de Cátedra

    Universidad de Valparaiso

    Chile

    2009 - 2010

  •   Ayudante de Cátedra

    Universidad de Valparaiso

    Chile

    2010 - 2011

  •   Alumno en Practica Profesional

    Instituto de Salud Publica de Chile

    Chile

    2011 - 2011

  •   Práctica Profesional

    Farmacias Cruz Verde

    Chile

    2010 - 2010

  •   Ayudante

    Universidad de Talca

    Chile

    2013 - 2016

Formación de Capital Humano


Carlos Albornoz Nuñez
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2017

Tamara Morgado Guzman
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2017

Francisca Mundaca Silva
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2017

Ivette Vásquez Salazar
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2017

Yoana Zurita Muñoz
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2017

Libia Campos Lepe
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Constanza López Troncoso
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Natalia Troncoso Bravo
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Camila Gonzalez Fernandez
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Barbara Prieto Ramirez
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Karen Navarro Galvez
Tesis de Pregrado (Nutrición y Dietética, Universidad de Talca)
Tutor: Felipe Jimenez Aspee
Terminada: 2018

Daniel Mieres Castro
Tesis de Doctorado en Ciencias, mención Investigación y Desarrollo de Productos Bioactivos (Universidad de Talca)
Co-tutor: Felipe Jimenez Aspee
Tutor: Guillermo Schmeda Hirschmann
Fecha de Termino: Marzo 2021


Difusión y Transferencia


2018 10th International Conference on Counter Current Chromatography. Braunschweig, Germany. August 1st-3rd. Oral Presentation.
2017 OCC World Congress 2015 and Annual SFRR-E Conference. Berlin, Germany. June 21st-24th. Poster Presentation.
2016 IX International Symposium on Natural Products Chemistry and Applications, Chillán, Chile. November 23-24th. Poster presentation.
2016 V tri-national meeting UTALCA UNICAMP UNCUYO, Campinas, Brazil. November 21-23rd. Oral Presentation.
2016 16th International Congress of Ethnopharmacology, Yulin, China, May 14-19th. Poster presentation.
2015 XIth Rubus and Ribes Symposium, Asheville, North Carolina, USA, June 21-24th. Poster presentation.
2014 14th International Congress of Ethnopharmacology, Puerto Varas, Chile, September 23-26th. Poster and Oral presentation.
2014 53rd Annual Meeting of the Phytochemical Society of North America, Raleigh, North Carolina, USA. August 9-13th. Poster presentation.
2013 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Hobart, Tasmania, Australia, November 18-21st.
Poster presentation.
2013 VIth International Conference on Polyphenols and Health, Buenos Aires, Argentina, October 16th -19th. Poster presentation.
2013 Sao Paulo Advanced School on Bioorganic Chemistry, Araraquara, Brazil, July 1st -5th. Poster presentation.
2012 VII International Symposium of Natural Products chemistry and their applications, Talca, Chile, November 5-8th. Poster presentation.
2012 VI Iberoamerican Conference on Alzheimer, Santiago, Chile, October 18th-20th. Oral presentation.
2012 XVII Chilean Conference of Clinical Chemistry, May 16th -18th. Poster presentation.

Training courses
2018 Workshop on Counter-current Chromatography (CCC) and Centrifugal Partition Chromatography (CPC), Technische Universität Braunschweig, Germany. July 30th-31st.
2016 9th International Metabolomics Workshop, University of Leiden, Netherlands, April 18-29th.
2013 Advanced HPLC method development using Quality by Design Short course, University of Tasmania, Hobart, Australia, November 17-18th.
2012 Free radicals, reactive species and antioxidants: from chemistry to physiopathology. FRAG-Chile, Santiago, Chile, Universidad Andrés Bello, December 4th.
2011 Human T-lymphotropic virus-1 (HTLV-1), Santiago, Chile. Chilean Institute of Public Health, March 8-9th.
2010 Human health and poultry chain. FANUS, Buenos Aires, Argentina. September 24th.
2010 Toxicology and Pesticide exposure surveillance: Chilean and Spanish experience. Health SEREMI, Valparaiso, Chile. June 30th.


Premios y Distinciones

  •   Alexander von Humboldt for Postdoctoral Studies

    ALEXANDER VON HUMBOLDT FOUNDATION

    Alemania, 2019

    Beca de Postdoctorado de la Fundacion Alexander von Humboldt

  •   Profesional Distinguido

    COLEGIO DE QUIMICO FARMACEUTICO DE CHILE A.G.

    Chile, 2019

    Profesional distinguido en el area de Investigación y Docencia Universitaria, Colegio Regional de Quimicos Farmaceuticos, sede Maule

  •   Young Scientist

    Lindau Nobel Laureate Foundation

    Chile, 2018

    Cientifico joven invitado a participar en la 67th Lindau Nobel Laureate Meeting on Chemistry

  •   Beca Iberoamerica Santander

    Banco Santander

    Chile, 2017

    Programa de Becas Iberoaméricas Santander para jovenes profesores e investigadores. Para realizar una pasantía de investigación en la Universidad de Castilla-La Mancha, España.

  •   Alumno destacado

    COLEGIO DE QUIMICO FARMACEUTICO DE CHILE A.G.

    Chile, 2013

    Mejor alumno graduado de la carrera de Química y Farmacia en el país

  •   Invited participant

    FUNDACION DE AMPARO A LA INVESTIGACION DEL ESTADO DE SAO PAULO

    Brasil, 2013

    Participante invitado al Sao Paulo Advanced School on Bioorganic Chemistry

  •   Dr. Ernesto Fernandez

    UNIVERSIDAD DE VALPARAISO

    Chile, 2012

    Al graduado con mejor promedio en Quimica Orgánica

  •   Alumno destacado

    FARMACIAS AHUMADA S.A.

    Chile, 2012

    Alumno destacado, con el mejor promedio en asignaturas de formación profesional

  •   Alumno destacado

    UNIVERSIDAD DE VALPARAISO

    Chile, 2012

    Alumno destacado generacion 2006-2012 de la carrera de "Quimica y Farmacia"

  •   Alumno destacado

    LABORATORIO SAVAL

    Chile, 2012

    Alumno destacado


 

Article (21)

Antioxidant activity and the isolation of polyphenols and new iridoids from Chilean Gaultheria phillyreifolia and G. poeppigii berries
Effect of simulated gastrointestinal digestion on polyphenols and bioactivity of the native Chilean red strawberry (Fragaria chiloensis ssp. chiloensis f. patagonica)
Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: in vitro and in silico studies
Changes in polyphenol composition and bioactivity of the native Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) after in vitro gastrointestinal digestion
Colonic fermentation of polyphenols from Chilean currants (Ribes spp.) and its effect on antioxidant capacity and metabolic syndrome-associated enzymes
Male sexual enhancers from the Peruvian Amazon
Polyphenolic profile and antioxidant activity of meristem and leaves from “chagual” (Puya chilensis Mol.), a salad from central Chile
Polyphenols from wild Chilean currants (Ribes spp.) increase the activity of intracellular antioxidant enzymes in human gastric AGS cells
Inhibition of pro-inflammatory enzymes by medicinal plants from the Argentinean highlands (Puna)
Qualitative and quantitative changes in polyphenol composition and bioactivity of Ribes magellanicum and R. punctatum after in vitro gastrointestinal digestion.
The native fruit Geoffroea decorticans from arid northern Chile: phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome-associated enzymes
Antioxidant activity and phenolic profiles of the wild currant Ribes magellanicum from Chilean and Argentinean Patagonia.
Chemical and functional characterization of seed, pulp and skin powder from chilto, an Argentine native fruit. Phenolic fractions affects key enzymes involved in metabolic syndrome and oxidative stress
Phenolics from the Patagonian currants Ribes spp.: Isolation, characterization and cytoprotective effect in human AGS cells
The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protectsagainst H2O2 and methylglyoxal-induced damage in AGS cells
Anti-inflammatory activity of Copao (Eulychnia acida Phil., Cactaceae) fruits
Antibacterial activity, antioxidant effect and chemical composition of propolis from the Region del MAule, central Chile
Chemical profiling and antioxidant activity of Bolivian propolis
Chilean Prosopis mesocarp flour: phenolic profiling and antioxidant activity
A new isoxazolic compound acts as alpha 7 nicotinic receptor agonists in human umbilical vein endothelial cells
Antioxidant activity and characterization of constituents in copao fruits (Eulychnia acida Phil., Cactaceae) by HPLC–DAD–MS/MSn

Proyecto (4)

Can the direct inoculation of Arbuscular mycorrhizal fungi modify the profiles and quantity of antioxdant compounds in flesh colored potatoes cropped under drought and P startvaton conditions
Polyphenolics: from analytical methods to health benefits
PHENOLIC CONTENT AND COMPOSITION FROM CHAURA BERRIES (GAULTHERIA PHILLYREIFOLIA AND G. POEPPIGII): ANTIOXIDANT ACTIVITY AND EFFECT ON CARBOHYDRATE METABOLISM USING CELL AND ENZYMATIC MODELS.
Phenolic metabolome of Chilean native nuts and seeds: antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome
13
Felipe Jimenez

Profesor Conferenciante

UNIVERSIDAD DE TALCA

Talca, Chile

3
Maria Theoduloz

Planta Profesional

UNIVERSIDAD DE TALCA

Talca, Chile

2
Katherine Márquez

Researcher

Researcher

Centro de Estudios en Alimentos Procesados

Talca, Chile

1
Samanta Thomas

Profesor Titular

Facultad de Farmacia

Universidad de Valparaíso

Valparaíso, Chile

1
Daniel Mieres

Postdoctorante

Instituto de Ciencias Biológicas

Universidad de Talca

Talca, Chile