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Maria Cristina Theoduloz Lafuente

Planta Profesional

UNIVERSIDAD DE TALCA

Talca, Chile

Chemistry of Natural Products; Structural modification of natural compounds; Biological activity of natural and semisynthetic compounds; Biological activity of naturally occurring and synthetic compounds; Action mechanisms of bioactive compounds in human cell cultures; Cytotoxicity and antiproliferative activity in human cell cultures

Licenciado en Biologia, UNIVERSIDAD DE CONCEPCION. Chile, 1981

Planta Profesional Full Time

UNIVERSIDAD DE TALCA

Ciencias de la Salud

Chile

1989 - At present

Asistente de investigacion Full Time

Universidad Nacional de Asuncion

Asuncion, Paraguay

1985 - 1988

Ivana Patricia Bravo Carrión
Tesis de Doctorado en Ciencias, mención Investigación y Desarrollo de Productos Bioactivos (Universidad de Talca)
Co-tutora: Cristina Theoduloz Lafuente
Tutor: Guillermo Schmeda Hirschmann
Terminada: 2014

Daniela Carolina Valenzuela Briceño
Tesis de Pregrado (Tecnología Médica, Universidad de Talca)
Tutora: Cristina Theoduloz Lafuente
Terminada: 2012

Fernanda Bustamante Troncoso
Tesis de Pregrado (Tecnología Médica, Universidad de Talca)
Tutores: Cristina Theoduloz Lafuente, Guillermo Schmeda Hirschmann
Terminada: 2012

Solange Cádiz Castillo
Tesis de Pregrado (Tecnología Médica, Universidad de Talca)
Tutores: Cristina Theoduloz Lafuente, Guillermo Schmeda Hirschmann
Terminada: 2012

Jesús Rodríguez Rodríguez
Tesis de Pregrado (Tecnología Médica, Universidad de Talca)
Tutora: Cristina Theoduloz Lafuente
Terminada: 2015


Arylated analogues of cypronazole: fungicidal effect and activity on human fibroblasts. Docking analysis and molecular dynamics simulations. Herrera Cano N., Andujar S.A., Theoduloz C., Wunderlin D.A., Santiago A.N., Schmeda-Hirschmann G., Enriz R.D., Feresin G.E. Article Natural Products and Bioprospecting (2022)
Iridoids and polyphenols from chilean Gaultheria spp. berries decrease the glucose uptake in Caco-2 cells after simulated gastrointestinal digestion Mieres-Castro, Daniel; Theoduloz, Cristina; Sus, Nadine; Burgos-Edwards, Alberto; Schmeda-Hirschmann, Guillermo; Frank, Jan; Jimenez-Aspee, Felipe Article ISI FOOD CHEMISTRY (2022)
Phenolic Composition and alpha-Glucosidase Inhibition of Leaves from Chilean Bean Landraces Alarcon-Esposito, Jazmin; Nina, Nelida; Theoduloz, Cristina; Burgos-Edwards, Alberto; Paillan, Hernan; Schmeda-Hirschmann, Guillermo Article ISI PLANT FOODS FOR HUMAN NUTRITION (2022)
Antiglycating Effect of Phenolics from the Chilean Currant Ribes cucullatum under Thermal Treatment Avila, Felipe; Ravello, Natalia; Manriquez, Camila; Jimenez-Aspee, Felipe; Schmeda-Hirschmann, Guillermo; Theoduloz, Cristina Article ISI ANTIOXIDANTS (2021)
Phenolic composition, antioxidant capacity and α-glucosidase inhibitory activity of raw and boiled Chilean Araucaria araucana kernels Schmeda-Hirschmann, Guillermo; Antileo-Laurie, Javier; Theoduloz, Cristina; Jiménez-Aspee, Felipe; Avila, Felipe; Burgos-Edwards, Alberto; Olate-Olave, Verónica Article FOOD CHEMISTRY (2021)
Thermal treatment of phenolics from the Patagonian currant Ribes cucullatum: effects on its antiglycating activity. Ávila, F., Ravello, N., Manriquez, C., Jiménez-Aspee, F., Schmeda-Hirschmann, G., Theoduloz, C. Article Antioxidants (2021)
Bioactive constituents from South American Prosopis and their use and toxicity. Schmeda-Hirschmann, G., Theoduloz, C., Jiménez-Aspee, F., Echeverría, J. Article CURRENT PHARMACEUTICAL DESIGN (2020)
Effects of gastrointestinal digested polyphenolic enriched extracts of Chilean currants (Ribes magellanicum and Ribes punctatum) on in vitro fecal microbiota. Burgos-Edwards, A., Fernández-Romero, A., Carmona, M., Thuissard-Vasallo, I., Schmeda-Hirschmann, G., Larrosa, M. Article FOOD RESEARCH INTERNATIONAL (2020)
Iridoids and amino acid derivatives from the Paraguayan crude drug Adenocalymma marginatum (ysypó hu). Schmeda-Hirschmann, G., Burgos-Edwards, A., Jimenez-Aspee, F., Mieres-Castro. D., Theoduloz, C., Pormetter. L., Fogel, R., Céspedes, C., Soria, N., Valdez, S. Article MOLECULES (2020)
Isolation and characterization of secondary metabolites from Gaultheria tenuifolia berries. Mieres-Castro, D., Schmeda-Hirschmann, G., Theoduloz, C., Rojas, A., Piderit, D., Jiménez-Aspee, F. Article JOURNAL OF FOOD SCIENCE (2020)
Phenolics from the Bolivian Highlands food plant Ombrophytum subterraneum (Aspl.) B. Hansen (Balanophoraceae): antioxidant and α-glucosidase inhibitory activity. Nina, N., Theoduloz, C., Giménez, A., Schmeda-Hirschmann, G. Article FOOD RESEARCH INTERNATIONAL (2020)
Andean Prumnopitys andina (Podocarpaceae) fruit extracts: characterization of secondary metabolites and potential cytoprotective effect. Jiménez-Aspee, F., Theoduloz, C., Pormetter, L., Mettke, J., Avila, F., Schmeda-Hirschmann, G. Article MOLECULES (2019)
Anti-inflammatory effect of polyphenols from Chilean currants (Ribes magellanicum and R. punctatum) after in vitro gastrointestinal digestion on Caco-2 cells. Larrosa, M., Burgos-Edwards, A., Martín Pérez, L., Jiménez-Aspee, F., Theoduloz, C., Schmeda Hirschmann, G. Article Joural of Functional Foods (2019)
Antioxidant activity and the isolation of polyphenosls and new iridoids from Chilean Gaultheria phillyreifolia and G. poeppigii berries. Mieres-Castro, D. Schmeda-Hirschmann, G., Theoduloz, C., Gómez-Alonso, S., Pérez-Navarro, J., Marquez, K., Jiménez-Aspee, F. Article FOOD CHEMISTRY (2019)
Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs Castro-Castillo, V., Fuentes-Retamal, S., Yañez, C., Ferreira, J., Cassels, B., Catalán, M., Cabezas, D., Suarez-Rozas, C., Theoduloz, C., Mella-Raipán, J., Simpson, S. Article Toxicology in vitro : an international journal published in association with BIBRA. (2019)
Effect of simulated gastrointestinal digestion on polyphenols and bioactivity of the native Chilean red strawberry (Fragaria chiloensis spp. chiloensis f. patagonica). Thomas-Valdés, S., Theoduloz, C., Jiménez-Aspee, F., Schmeda-Hirschmann, G. Article FOOD RESEARCH INTERNATIONAL (2019)
Effect of simulated gastrointestinal digestion on polyphenols and bioactivity of the native Chilean red strawberry (Fragaria chiloensis ssp. chiloensis f. patagonica) Thomas-Valdés, Samanta; THEODULOZ, CRISTINA; Jiménez-Aspee, Felipe; Schmeda-Hirschmann, Guillermo Article ISI SCOPUS FOOD RESEARCH INTERNATIONAL (2019)
Fabiana imbricata Ruiz et Pav. (Solanaceae), a review of an important Patagonian medicinal plant. Schmeda-Hirschmann G., Theoduloz C. Article JOURNAL OF ETHNOPHARMACOLOGY (2019)
Male sexual enhancers from the Peruvian Amazon. Schmeda-Hirschmann, G., Burgos-Edwards, A., Theoduloz, C., Jiménez-Aspee, F., Vargas-Arana, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2019)
Patagonian berries as native food and medicine. Schmeda-Hirschmann, G., Jimenez-Aspee, F., Theoduloz, C., Ladio, A.H. Article JOURNAL OF ETHNOPHARMACOLOGY (2019)
Phenolic, oxylipin and fatty acid profiles of the Chilean hazelnut(Gevuina avellana): Antioxidant activity and inhibition of pro-inflammatory and metabolic syndrome-associated enzymes. Pino Ramos, L., Jiménez-Aspee, F., Theoduloz, C., Burgos-Edwards, A., Domínguez-Perles, R., Oger, C., Durand, T., Gil-Izquierdo, A., Bustamante, L., Mardones, C., Márquez, K., Contreras, D., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2019)
Polyphenol composition and (bio)activity of Berberis species and wild strawberry from the Argentinean Patagonia. Chamorro, M., Reiner, G., Theoduloz, C., Ladio, A., Schmeda-Hirschmann, G., Gómez-Alonso, S., Jiménez-Aspee, F. Article MOLECULES (2019)
Changes in polyphenol composition and bioactivity of the native Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) after in vitro gastrointestinal digestion. Thomas-Valdés S., Theoduloz C., Jiménez-Aspee F., Burgos-Edwards A., Schmeda-Hirschmann G. Article FOOD RESEARCH INTERNATIONAL (2018)
Cholinesterase inhibition activity, alkaloid profiling and molecular docking of Chilean Rhodophiala (Amaryllidaceae). Tallini L.R., Bastida J., Cortes N, Osorio E.H., Theoduloz C., Schmeda-Hirschmann G. Article Molecules (2018)
Colonic fermentation of polyphenols from Chilean currants (Ribes spp.) and its effect on antioxidant activity and metabolic syndrome-associated enzymes. Burgos-Edwards, A., Jiménez-Aspee, F., Theoduloz, C., Schmeda-Hirschmann, G. Article Food Chemistry (2018)
Effect of polyphenols from wild Chilean currants (Ribes spp.) on the activity of intracellular antioxidant enzymes in human gastric cells. Theoduloz, C., Burgos-Edwards, A., Schmeda-Hirschmann, G., Jiménez-Aspee, F. Article Food Bioscience (2018)
Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: in vitro and in silico studies. Theoduloz, C., Alzate-Morales, J., Jiménez-Aspee, F., Isla, Alberto, M.R., Pertino, M.W., Schmeda-Hirschmann, G. Article Chemical Biology & Drug Design (2018)
Neuroprotective effects of ferruginol, jatrophone, and junicedric acid against Aβ injury in hippocampal neurons. Zolezzi, J.M., Lindsay, C.B., Serrano, F.G., Ureta, R.C., Theoduloz, C., Schmeda-Hirschmann, G., Inestrosa, N.C. Article ISI Journal of Alzheimer's Disease (2018)
Oligostilbenoids in Pinot Noir Grape Cane Extract: Isolation, Characterization, Antioxidant Capacity and in vitro Anti-proliferative Effect on Cancer Cells. Sáez V., Pastene E., Vergara C., Mardones C., Hermosín-Gutiérrez I., Gómez-Alonso S., Gómez M.V., Theoduloz C., von Baer D. Article FOOD CHEMISTRY (2018)
Polyphenolic profile and antioxidant activity of meristem and leaves from “chagual” (Puya chilensis Mol.), a salad from central Chile. Jiménez-Aspee F., Theoduloz C.; Gómez-Alonso S., Article FOOD RESEARCH INTERNATIONAL (2018)
Access to new cytotoxic quinone-amino acid conjugates linked through a vinylic spacer from 2- acylnaphthoquinones and methyl 3-aminocrotonate. [107] Valderrama J.A., Garrido J., Delgado V., Benites J., Theoduloz C. Article MOLECULES (2017)
Cytoprotective mechanisms mediated by polyphenols from Chilean native berries against free radical-induced damage on AGS cells. Ávila F., Theoduloz C., López-Alarcón C., Dorta E., Schmeda-Hirschmann G. Article Oxidative Medicine and Cellular Longevity (2017)
Qualitative and quantitative changes in polyphenol composition and bioactivity of Ribes magellanicum and R. punctatum after in vitro gastrointestinal digestion Burgos-Edwards A., Jiménez-Aspee F., Thomas-Valdés S., Schmeda-Hirschmann G., Theoduloz C. Article ISI SCOPUS FOOD CHEMISTRY (2017)
The Native Fruit Geoffroea decorticans from the Arid Northern Chile: Phenolic Composition, Antioxidant Activities and In Vitro Inhibition of Pro-Inflammatory and Metabolic Syndrome-Associated Enzymes. Jiménez-Aspee F., Theoduloz C., Soriano M.D.P.C., Ugalde-Arbizu M., Alberto M.R., Zampini I.C., Isla M.I., Simirigiotis M.J., Schmeda-Hirschmann G. Article Molecules (2017)
Antioxidant activity and phenolic profiles of the wild currant Ribes magellanicum from Chilean and Argentinean Patagonia. Jiménez-Aspee F., Thomas-Valdés S., Schulz A., Ladio A., Theoduloz C., Schmeda-Hirschmann G. Article Food Science & Nutrition (2016)
Antiproliferative activity and chemical composition of the venom from the Amazonian toad Rhinella marina (Anura: Bufonidae). Schmeda-Hirschmann G, Quispe C, Vargas Arana G, Theoduloz C, Urra FA, Cárdenas C. Article TOXICON (2016)
Chemical profiling and antioxidant activity of Bolivian propolis. Nina V., Quispe C., Jimenez-Aspee F., Theoduloz C., Gimenez A., Schmeda-Hirschmann G. Article ISI JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2016)
Phenolics from the Patagonian currants Ribes spp.: Isolation, characterization and cytoprotective effect in human AGS cells. Jiménez-Aspee F., Theoduloz C., Neves Vieira M., Rodríguez-Werner M.A., Schmalfuss E., Winterhalter P., Schmeda-Hirschmann G. Article JOURNAL OF FUNCTIONAL FOODS (2016)
Synthesis and Cytotoxic Activity on Human Cancer Cells of Novel Isoquinolinequinone-Amino Acid Derivatives Valderrama, JA; Delgado, V; Sepulveda, S; Benites, J; Theoduloz, C; Calderon, PB; Muccioli, GG Article ISI SCOPUS MOLECULES (2016)
Synthesis and cytotoxic activity on human cancer cells of novel isoquinolinequinone-amino acid derivatives. Valderrama JA, Delgado V, Sepúlveda S, Benites J, Theoduloz C, Buc Calderon P, Muccioli GG. Article Molecules (2016)
The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 or methylglyoxal-induced damage in AGS cells. Jiménez-Aspee, F., Theoduloz, C., Avila, F., Thomas-Valdés, S., Mardones, C., von Baer, D., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2016)
Anti-inflammatory activity of Copao (Eulychnia acida Phil., Cactaceae) fruits. Jimenez-Aspee, F., Alberto, M.R., Quispe, C., Soriano, M. del P.C., Theoduloz, C., Isla, M.I., Schmeda-Hirschmann, G. Article Plant Foods for Human Nutrition (2015)
Anti-inflammatory activity of Copao (Eulychnia acida Phil., Cactaceae) fruits. Jimenez-Aspee, F., Alberto, M.R., Quispe, C., Soriano, M. del P.C., Theoduloz, C., Isla, M.I., Schmeda-Hirschmann, G. Article ISI PLANT FOODS FOR HUMAN NUTRITION (2015)
Antibacterial activity, antioxidant effect and chemical composition of propolis from Región del Maule, central Chile. Nina, V., Quispe, C., Jimenez-Aspee, F., Theoduloz, C., Leiva, E., Feresin, G.E., Lima, B., Schmeda-Hirschmann, G. Article ISI Molecules (2015)
Chilean Prosopis Mesocarp Flour: Phenolic Profiling and Antioxidant Activity Schmeda-Hirschmann G., Quispe C., Soriano MPDC, Theoduloz C, Jiménez-Aspée F, Pérez MJ, Cuello AS, Isla MI Article ISI MOLECULES (2015)
Chilean Prosopis Mesocarp Flour: Phenolic Profiling and Antioxidant Activity. Guillermo Schmeda-Hirschmann, Cristina Quispe, Maria del Pilar C. Soriano, Cristina Theoduloz, Felipe Jiménez-Aspée, Maria Jorgelina Pérez, Ana Soledad Cuello and Maria Inés Isla. Article Molecules (2015)
Efficacy of quercetin against chemically induced murine oral squamous cell carcinoma. Droguett D., Castillo C., Leiva E., Theoduloz C., Schmeda-Hirschmann G., Kemmerling U. Article ONCOLOGY LETTERS (2015)
Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic acid and carnosol derivatives. Pertino, M.W., Theoduloz, C., Butassi, E., Zacchino, S., Schmeda-Hirschmann, G. Article MOLECULES (2015)
Topical Anti-inflammatory Activity of New Hybrid Molecules of Terpenes and Synthetic Drugs. Theoduloz C., Delporte C., Valenzuela-Barra G., Silva X., Cadiz S., Bustamante F., Pertino M.W., Schmeda Hirschmann G. Article Molecules (2015)
Topical Anti-inflammatory Activity of New Hybrid Molecules of Terpenes and Synthetic Drugs. Theoduloz C., Delporte C., Valenzuela-Barra G., Silva X., Cadiz S., Bustamante F., Pertino M.W., Schmeda Hirschmann G. Article MOLECULES (2015)
Antioxidant activity and characterization of constituents in copao fruits (Eulychnia acida Phil., Cactaceae) by HPLC-DAD-MS/MSn Jimenez-Aspee, F; Quispe C.; Soriano, MDPC; Gonzalez, JF; Haneke, E; Theoduloz, C; Schmeda-Hirschmann G. Article FOOD RESEARCH INTERNATIONAL (2014)
Antioxidant activity and characterization of constituents in Copao fruits(Eulychnia acida Phil., Cactaceae) by HPLC-DAD-MS/MS. Felipe Jiménez-Aspee, Cristina Quispe, Maria del Pilar C. Soriano, Jaime Fuentes Gonzalez, Eva Hünecke, Cristina Theoduloz, Guillermo Schmeda-Hirschmann. Article Food International Research (2014)
Antioxidant effect and characterization of South American Prosopis pods syrup. Quispe C., Petroll K., Theoduloz C., Schmeda Hirschmann G. Article Food International Research (2014)
Antioxidant effect and characterization of South American Prosopis pods syrup. Quispe C., Petroll K., Theoduloz C., Schmeda Hirschmann G. Article Food Research International (2014)
Antiproliferative activity and new argininyl bufadienolide esters from the "cururu" toad Rhinella (Bufo) schneideri Schmeda-Hirschmann G.; Quispe C.; Theoduloz, C; De Sousa, PT; Parizotto, C Article JOURNAL OF ETHNOPHARMACOLOGY (2014)
Antiproliferative activity and new argininyl bufadienolide esters from the “Cururú” toad Rhinella (Bufo) schneideri. Guillermo Schmeda-Hirschmann, Cristina Quispe, Cristina Theoduloz, Paulo Teixeira de Sousa Jr., Carlos Parizotto. Article JOURNAL OF ETHNOPHARMACOLOGY (2014)
Gastroprotective Mechanisms of Action of Semisynthetic Carnosic Acid Derivatives in Human Cells Theoduloz, C; Pertino M.W.; Schmeda-Hirschmann G. Article Molecules (2014)
Gastroprotective mechanisms of action of semisynthetic carnosic acid derivatives in human cells. Theoduloz, C., Pertino, M.W., Schmeda-Hirschmann, G. Article MOLECULES (2014)
Synthesis and antiproliferative activity of novel triazole derivatives from dehydroabietic acid. Mariano Walter Pertino, Valery Verdugo, Cristina Theoduloz, Guillermo Schmeda-Hirschmann. Article MOLECULES (2014)
Synthesis and Antiproliferative Activity of Some Novel Triazole Derivatives from Dehydroabietic Acid Pertino, MW; Verdugo V.; Theoduloz, C; Schmeda-Hirschmann G. Article Molecules (2014)
Synthesis and antiproliferative evaluation of new isomeric ellipticine quinones. Valderrama J., Ibacache A., Theoduloz C. Article BLACPMA (2014)
Synthesis and antiproliferative evaluation of new isomeric ellipticine quinones. Valderrama J., Ibacache A., Theoduloz C. Article BLACPMA (2014)
Synthesis and in vitro antiproliferative evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones Rios, D; Benites, J; Torrejon, F; Theoduloz, C; Valderrama, JA Article MEDICINAL CHEMISTRY RESEARCH (2014)
Synthesis and in vitro antiproliferative evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones David Ríos, Julio Benites, Felipe Torrejón, Cristina Theoduloz, Jaime A. Valderrama. Article MEDICINAL CHEMISTRY RESEARCH (2014)
Synthesis, Half-Wave Potentials and Antiproliferative Activity of 1-Aryl-substituted Aminoisoquinolinequinones Ibacache J.A.; Delgado, V; Benites, J; Theoduloz, C; Arancibia V.; Muccioli G.G.; Valderrama J.A. Article Molecules (2014)
Synthesis, half-wave potentials and antiproliferative activity of 1-aryl-substituted aminoisoquinolinequinones. J.A. Ibacache, V. Delgado, J. Benites, C. Theoduloz, V. Arancibia, G. G. Muccioli, J. A. Valderrama. Article MOLECULES (2014)
Annulation of substituted anthracene-9,10-diones yields promising selectively antiproliferative compounds. V. Castro, C. Suarez, N. Castro, C. Theoduloz, B. Cassels. Article ISI EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
1,2,3-Triazole-substituted oleanolic acid derivatives: synthesis and antiproliferative activity. Mariano Pertino, Cecilia Lopez, Cristina Theoduloz, Guillermo Schmeda-Hirschmann. Article MOLECULES (2013)
Dimeric labdane diterpenes: synthesis and antiproliferative effect. Mariano Pertino, Cristina Theoduloz, Marco Bastias, Guillermo Schmeda-Hirschmann Article MOLECULES (2013)
Diterpenylquinone Hybrids: Synthesis and Assessment of Gastroprotective Mechanisms of Action in Human Cells Theoduloz, C; Bravo, I; Pertino, MW; Schmeda-Hirschmann G. Article Molecules (2013)
Diterpenylquinone Hybrids: Synthesis and Assessment of Gastroprotective Mechanisms of Action in Human Cells. Theoduloz, C.; Bravo, I.; Pertino, M.W.; Schmeda-Hirschmann, G. Article MOLECULES (2013)
Synthesis and in Vitro Antiproliferative Activity of New Phenylaminoisoquinolinequinones against Cancer Cell Lines Delgado, V; Ibacache, A; Arancibia V.; Theoduloz, C; Valderrama, JA Article Molecules (2013)
Synthesis and in vitro antiproliferative activity of new phenylaminoisoquinolinequinones against cancer cell lines. Virginia Delgado, Andrea Ibacache, Verónica Arancibia, Cristina Theoduloz, Jaime Valderrama. Article MOLECULES (2013)
. Potential gastroprotective effect of novel cyperenoic acid-quinone derivatives in human cell cultures. C. Theoduloz, I. Bravo Carrión, M. Pertino, D. Valenzuela, G. Schmeda-Hirschmann. Article PLANTA MEDICA (2012)
Argentinean Amaryllidaceae Wild, a New Renewable Source of Acetylcholinesterase Inhibitor Galanthamine and Other Alkaloids. J.E. Ortiz, S. Berkov, N. B. Pigni, C. Theoduloz, G. Roitman, A. Tapia, J. Bastida, G.E. Feresin. Article MOLECULES (2012)
Biological activities and correlations tendency of electrochemical properties of some indolizino[1,2-b]quinoline derivatives. A. Cañete, F. Armijo, M. A. Del Valle, R.A. Tapia, C. Theoduloz, C. D. Pessoa, G. Recabarren. Article Journal of the Chilean Chemical Society (2012)
New Gastroprotective Labdeneamides from (4S,9R,10R) methyl 18-carboxi-labda-8,13(E)-diene-15-oate. Olate V., Pertino M.W., Theoduloz C., Yesilada E., Monsalve F., González P., Droguett D., Richomme P., Hadi A.H.A., Schmeda-Hirschmann G. Article PLANTA MEDICA (2012)
Synthesis and antitumor evaluation of 6-aryl-substituted benzo j phenanthridine- and benzo gpyrimido4,5-c isoquinolinequinones. J. Iribarra, D. Vásquez, C. Theoduloz, J. Benites, D. Ríos, J.A. Valderrama. Article MOLECULES (2012)
Synthesis and in vitro cytotoxic evaluation of aminoquinones structurally related to marine isoquinolinequinones. V. Delgado, A. Ibacache, C. Theoduloz, J.A. Valderrama. Article MOLECULES (2012)
Gastroprotective effect and cytotoxicity of labdeneamides with amino acids. Schmeda-Hirschmann G, Rodríguez JA, Theoduloz C, Yáñez T, Valderrama J. Article PLANTA MEDICA (2011)
Gastroprotective Effect of Carnosic Acid Derivatives. Theoduloz C, Pertino M, Rodríguez JA, Schmeda-Hirschmann G. Article PLANTA MEDICA (2011)
Studies on Quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents. Valderrama J., Ibacache A, Theoduloz C, Benitez-Vilchez J. Article EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Synthesis and pharmacological activity of diterpenylnaphthoquinone derivatives. Pertino, M.W., Theoduloz, C., Palenzuela, J.A., Afonso, M. del M., Yesilada, E., Monsalve, F., González, P., Droguett, D., Schmeda-Hirschmann, G. Article MOLECULES (2011)
Gastroprotective effect of carnosic acid γ-lactone derivatives. Pertino M, Theoduloz C, Rodríguez JA, Yáñez T, Lazo V, Schmeda-Hirschmann G. Article JOURNAL OF NATURAL PRODUCTS (2010)
Studies on Quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimido-isoquinolinequinones. Vasquez D., Rodríguez J., Theoduloz C., Buc Calderón P., Valderrama J. Article ISI EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis of Lakshminine and Antiproliferative Testing of Related Oxoisoaporphines Castro-Castillo, V; Rebolledo-Fuentes, M; Theoduloz, C; CASSELS, BK Article ISI SCOPUS Journal of Natural Products (2010)
Synthesis, Gastroprotective Effect and Cytotoxicity of New Amino Acid Diterpene Monoamides and Diamides Schmeda-Hirschmann, G; Pertino, MW; Rodriguez JA.; Monsalve, F; Droguett, D.; Theoduloz, C Article ISI SCOPUS MOLECULES (2010)
Antiproliferative activity of arborescidine alkaloids and derivatives. Santos S. L., Theoduloz C., Pilli R.A., Rodríguez, JA. Article EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
Antiproliferative activity of the diterpenes jatrophone and jatropholone and their derivatives. Theoduloz C., Rodríguez J.A., Pertino M, Schmeda-Hirschmann G. Article PLANTA MEDICA (2009)
Comparison of phenolic composition and antioxidant properties of two native Chilean and one domestic strawberry genotypes. Simirgiotis, M.J., Theoduloz, C., Caligari, P.D.S., Schmeda-Hirschmann, G. Article FOOD CHEMISTRY (2009)
Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean lamiaceae Sphacele chamaedryoides (Balbis) Briq. Areche C., Schmeda-Hirschmann G., Theoduloz, C., Rodriguez J. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2009)
Studies on Quinones. Part 45. Novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines. Valderrama J.A., Ibacache A.J., Arancibia V., Rodríguez J.A., Theoduloz C. Article BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Synthesis and Antitumor evaluation of 8-phenylaminopyrimido [4,5-c]isoquinolinequinones. Vásquez D., Rodriguez J.A. Theoduloz C., Verrax J., Buc Calderon P, Valderrama J.A. Article BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2009)
Synthesis and Antitumor Evaluation of Thiophene Analogues of Kigelinone Valderrama J.A., Espinoza O., Rodríguez J., Theoduloz C. Article Letters in Organic Chemistry (2009)
Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. Backhouse N., Rosales L., Apablaza C., Goity L., Erazo S., Negrete R., Theoduloz C., Rodríguez J., Delporte C. Article JOURNAL OF ETHNOPHARMACOLOGY (2008)
Cycloaspeptide A and pseurotin A from the endophytic fungus Penicillium janczewskii. Schmeda-Hirschmann, G., Hormazabal, E., Rodríguez, J., Theoduloz, C. Article Zeitschrift zur Naturforschung C (2008)
Gastroprotective activity of ferruginol in mice and rats: effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls. Areche C, Theoduloz C, Yáñez T, Souza-Brito ARM, Barbastefano V, de Paula D, Ferreira AL, Schmeda-Hirschmann G, Rodríguez JÁ. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2008)
New gastroprotective effect with selective cytotoxicity againstgastric cancer cells. Espinoza M., Santos L.S., Theoduloz C., Schmeda-Hirschmann G., Rodríguez J.A. Article PLANTA MEDICA (2008)
Studies on quinones. Part 43: Synthesis and cytotoxic evaluation of polyoxyethilene-containing 1,4-napthoquinones. Valderrama J., Leiva H., Rodríguez J.A., Theoduloz C., Schmeda-Hirschmann G. Article BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Studies on Quinones. Part 44. Novel Angucyclinone N-Heterocyclic Analogues Endowed with Antitumoral Activity. J.A. Valderrama, P. Colonelli, D. Vásquez, M.F. González, J. A. Rodríguez, C. Theoduloz. Article BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Biotransformation of Jatrophone by Aspergillus niger ATCC 16404. Pertino M, Schmeda-Hirschmann G, Santos S L, Rodríguez JA, Theoduloz C. Article Zeitschrift zur Naturforschung B (2007)
Biotransformation of Imbricatolic Acid by Aspergillus niger, Cunninghamella echinulata and Rhizopus nigricans Cultures. Schmeda-Hirschmann G, Aranda C, Kurina M, Rodríguez JA, Theoduloz C. Article MOLECULES (2007)
Free radical scavengers from Cymbopogon citratus (DC.) Stapf. plants cultivated in bioreactors by the temporary immersion (TIS)-principle. Tapia A, Cheel J, Theoduloz C, Rodríguez JA, Schmeda-Hirschmann G, Gerth A, Wilken D, Jordan M, Jiménez-González E, Gomez-Kosky R, Quiala Mendoza E. Article Zeitschrift zur Naturforschung C (2007)
Free radical scavenging activity and phenolic content in achenes and thalamus from Fragaria chiloensis ssp. chiloensis (f. chiloensis), F. chiloensis ssp. chiloensis (f. patagonica), F. vesca and F. ananassa cv. Chandler. Cheel J, Theoduloz C, Rodríguez JA, PDS Caligari, Schmeda-Hirschmann G. Article FOOD CHEMISTRY (2007)
Free radical scavenging activity and secondary metabolites from in vitro cultures of Sanicula graveolens. Cheel J, Schmeda-Hirschmann G, Jordan M, Theoduloz C, Rodríguez JA, Gerth A, Wilken D. 2007. Article Zeitschrift zur Naturforschung C (2007)
Gastroprotective and cytotoxic effect of semisynthetic ferruginol derivatives. Areche C, Rodríguez JA, Razmilic I, Yánez T, Theoduloz C, Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Gastroprotective effect and cytotoxicity of labdenamides. Izquierdo R, Astudillo L, Rodríguez JA, Theoduloz C, Palenzuela JA, Schmeda-Hirschmann G. Article PLANTA MEDICA (2007)
Gastroprotective effect and cytotoxicity of semisynthetic jatropholone derivatives. Pertino M, Schmeda-Hirschmann G, Rodríguez JA, Theoduloz C. Article PLANTA MEDICA (2007)
Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug “yagua rova” (Jatropha isabelli). Pertino M, Schmeda-Hirschmann G, Rodríguez JA, Theoduloz C. Article JOURNAL OF ETHNOPHARMACOLOGY (2007)
Gastroprotective activity of cyperenoic acid derivatives. Pertino M, Rodríguez JA, Theoduloz C, Razmilic I, Schmeda-Hirschmann G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models. Rodríguez, J.A., Theoduloz, C., Yánez, T., Becerra, J., Schmeda-Hirschmann, G. Article LIFE SCIENCES (2006)
Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships. M. Sánchez, C. Theoduloz, G. Schmeda-Hirschmann, I. Razmilic, T. Yánez, J.A. Rodríguez. Article LIFE SCIENCES (2006)
Studies on Quinones. Part 40. Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products. Valderrama J, Espinoza O, Gonzalez F, Tapia R, Rodríguez JA, Theoduloz C, Schmeda-Hirschmann G. Article TETRAHEDRON (2006)
Synthesis and Cytotoxic Activity of Isoquinoline-containing Polycyclic Quinones. Valderrama JA, González MF, Pessoa-Mahana D, Tapia RA, Fillion H, Pautet F, Rodríguez JA, Theoduloz C, Schmeda-Hirschmann G. Article BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Bioactive Metabolites from the Fungus Nectria galligena, the Main Apple Canker Agent in Chile. M. Gutiérrez, C. Theoduloz, J.A. Rodríguez, M. Lolas, G. Schmeda-Hirschmann. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
E-cinnamic acid derivatives and phenolics from the Chilean strawberry fruits, Fragaria chiloensis ssp.chiloensis. J. Cheel, C. Theoduloz, J.A. Rodríguez, G. Saud, P.D.S. Caligari, G. Schmeda-Hirschmann. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
Free radical scavengers and antioxidants from Lemongrass (Cymbopogon citratus)(DC.) Stapf. Cheel, J., Theoduloz, C., Rodríguez, J., Schmeda-Hirschmann, G. Article JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
Gastroprotective activity of a new semisynthetic solidagenone derivative. Rodríguez, J., Theoduloz, C., Sánchez, M., Yáñez, T., Razmilic, I., Schmeda-Hirschmann, G. Article JOURNAL OF PHARMACY AND PHARMACOLOGY (2005)
Gastroprotective Activity of Sesquiterpene Derivatives from Fabiana imbricata. Reyes, M., Schmeda-Hirschmann, G., Razmilic, I., Theoduloz, C., Yañez, T., Rodríguez, J. Article PHYTOTHERAPY RESEARCH (2005)
Gastroprotective and cytotoxic effect of dehydroabietic acid derivatives. B. Sepúlveda, L. Astudillo, J.A. Rodríguez, T. Yáñez, C. Theoduloz, G. Schmeda-Hirschmann. Article PHARMACOLOGICAL RESEARCH (2005)
Gastroprotective and ulcer-healing effect of new solidagenone derivatives in human cell cultures. Rodríguez, J., Theoduloz, C., Sánchez, M., Razmilic, I., Schmeda-Hirschmann, G. Article LIFE SCIENCES (2005)
Gastroprotective effect and cytotoxicity of natural and semisynthetic labdane diterpenes from Araucaria araucana. Schmeda-Hirschmann G, Astudillo SL, Sepúlveda VB, Rodríguez CJ, Theoduloz C, Yáñez T, Palenzuela JA. Article Zeitschrift zur Naturforschung C (2005)
Gastroprotective effect of the Mapuche crude drug Araucaria araucana resin and its main constituents. G. Schmeda-Hirschmann, L. Astudillo, Jaime Rodríguez, C. Theoduloz, T. Yáñez. Article JOURNAL OF ETHNOPHARMACOLOGY (2005)
Involvement of ethylene in stress-induced expression of the TLC1.1 retrotransposon from Lycopersicon chilense. Tapia G., Verdugo I., Yañez M., Ahumada I., Theoduloz C., Cordero C., Poblete F., González E., Ruiz-Lara S. Article PLANT PHYSIOLOGY (2005)
Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum. Hormazábal, E., Schmeda-Hirschmann, G., Astudillo, L., Rodriguez, J., Theoduloz, C. Article Zeitschrift zur Naturforschung C (2005)
Proximate composition and free radical scavening activity of edible fruits from the argentinian Yungas. Guillermo Schmeda Hirschmann, Gabriela Feresin, Alejandro Tapia, Norma Hilgert, Cristina Theoduloz Article JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2005)
Secondary metabolites from endophytic fungi isolated from the Chilean gymnosperm Prumnopitys andina(Lleuque). Schmeda-Hirschmann, G., Hormazabal, E., Astudillo, L., Rodriguez, J., Theoduloz, C. Article World Journal of Microbiology and Biotechnology (2005)
Synthesis of tricyclic analogs of stephaoxocanidine and their evaluation as acetycholinesterase inhibitors. Bianchi, D., Schmeda-Hirschmann, G., Theoduloz, C., Bracca, A., Kaufmann, T. Article BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2005)
Free radical Scavengers and Antioxidants from Baccharis grisebachii. Tapia, A., Rodriguez, J. A., Theoduloz, C., López, S., Feresin, G., Schmeda-Hirschmann, G. Article JOURNAL OF ETHNOPHARMACOLOGY (2004)
Free radical scavengers and antioxidants from Tagetes mendocina. G. Schmeda-Hirschmann, A. Tapia, C. Theoduloz, J. Rodríguez, S. López y G. E. Feresin. Article Zeitschrift zur Naturforschung C (2004)
Bioactive alkyl phenols and embelin from Oxalis erythrorhiza. G.E. Feresin, A. Tapia, M Sortino, S. Zacchino, A.R. Arias, A. Inchausti, G. Yaluff, J. Rodriguez, C. Theoduloz y G. Schmeda-Hirschmann. Article JOURNAL OF ETHNOPHARMACOLOGY (2003)
Expression of a -endotoxin cry1Ab gene in Bacillus subtilis and Bacillus licheniformis strains that naturally colonize the phylloplane of tomato plants. C. Theoduloz, A. Vega, M. Salazar, E. González, y L. Meza-Basso. Article JOURNAL OF APPLIED MICROBIOLOGY (2003)
Free radical scavengers and antioxidants from Peumus boldus Mol. ("Boldo"). G. Schmeda-Hirschmann, L. Astudillo, C. Theoduloz, J. Rodríguez, G. Feresin y A. Tapia. Article FREE RADICAL RESEARCH (2003)
RFLP-PCR identification of endemic Chilean species belonging to genus Rhagoletis. M. Salazar, C. Theoduloz, A. Vega, F. Poblete, E. González, R. Badilla y L. Meza-Basso. Article BULLETIN OF ENTOMOLOGICAL RESEARCH (2002)
Biologically active alkaloids and a free radical scavenger from Prosopis species. A. Tapia, G. Feresin, D. Bustos, L. Astudillo, C. Theoduloz, y G. Schmeda-Hirschmann. Article JOURNAL OF ETHNOPHARMACOLOGY (2000)
Relative toxicity of native Chilean Bacillus thuringiensis strains against Scrobipalpuloides absoluta (Lepidoptera: Gelechiidae). C. Theoduloz, P. Román, J. Bravo, C. Padilla, C. Vásquez y L. Meza-Basso. Article JOURNAL OF APPLIED MICROBIOLOGY (1997)
Biological activity of medicinal plants of Ica (Perú). S. Klinar, P. Castillo, A. Chang, G. Schmeda-Hirschmann, S. Reyes, C. Theoduloz, I. Razmilic. Article FITOTERAPIA (1995)
Effect of Fabiana imbricata constituents on Rhopalosiphon padi and Heliothis zea. G. Schmeda-Hirschmann, P. Román, C. Theoduloz, C. Donoso y L. Corcuera. Article PHYTOTHERAPY RESEARCH (1995)
Specificity and insecticidal activity of chilean strains of Bacillus thuringiensis. M. Vásquez, C. Parra, E. Hubert, P. Espinoza, C. Theoduloz y L. Meza-Basso. Article JOURNAL OF INVERTEBRATE PATHOLOGY (1995)
Hypotensive and diuretic effect of Equisetum bogotense and Fuchsia magellanica extracts in rats and micropropagation of E. bogotense. J. Rodríguez, P. Pacheco, I. Razmilic, J.I. Loyola, G. Schmeda-Hirschmann y C. Theoduloz. Article PHYTOTHERAPY RESEARCH (1994)
Chilean potato germplasm with resistance to potato viruses Y and S. J. Sáez-Vásquez, C. Theoduloz, F. Poblete, A. Contreras, E. Hubert y L. Meza-Basso. Article EUPHYTICA (1993)
Rutin and scopoletin content and micropropagation of Fabiana imbricata. I. Razmilic, G. Schmeda-Hirschmann, M. Dutra-Behrens, S. Reyes, I. López y C. Theoduloz. Article PLANTA MEDICA (1993)
The incidence of potato viruses X, Y and S in the Chilota Potato Collection. C. Theoduloz, J. Sáez-Vásquez, F. Poblete, A. Contreras, E. Hubert y L. Meza.Basso. Article American Potato Journal (1992)
Xanthine oxidase inhibitory activity of Chilean Myrtaceae. C. Theoduloz, P. Pacheco y G. Schmeda-Hirschmann. Article JOURNAL OF ETHNOPHARMACOLOGY (1991)
Xanthine oxidase inhibitory activity of Paraguayan Myrtaceae. C. Theoduloz, L. Franco, E. Ferro y G. Schmeda-Hirschmann. Article JOURNAL OF ETHNOPHARMACOLOGY (1988)
Preliminary pharmacologycal studies on Eugenia uniflora leaves: xanthine oxidase inhibitory activity. G. Schmeda-Hirschmann, C. Theoduloz, L. Franco, E. Ferro y A. Rojas de Arias. Article JOURNAL OF ETHNOPHARMACOLOGY (1987)
Pyrrolizidine alkaloid content in some Senecio grisebachii populations. G. Schmeda-Hirschmann, E. Ferro, C. Céspedes, L. Recalde y C. Theoduloz. Article FITOTERAPIA (1987)
Pyrrolizidine alkaloids from Senecio brasiliensis populatinos. G. Schmeda-Hirschmann, E. Ferro, L. Franco, L. Recalde y C. Theoduloz. Article JOURNAL OF NATURAL PRODUCTS (1987)
Desmidiceas (Saccodermae y Placodermae) de Chile. IV. Demidiaceas del sistema de lagos de la Cordillera del Paine y alrededores. C. Theoduloz y O. Parra. Article Scielo GAYANA BOTANICA (1984)


Cytoprotective effects of Chilean wild currants (Ribes spp.) against oxidative stress mediated by enhancing the activity of cellular antioxidant enzymes Jimenez-Aspee, F; Theoduloz, C; Schmeda-Hirschmann, G Abstract ISI FREE RADICAL BIOLOGY AND MEDICINE (2017)


Ethnopharmacology as a basis for medicinal chemistry studies: combining natural products and semisynthesis for gastroprotective agents Schmeda-Hirschmann, G., Theoduloz, C.; Mukherjee, P. ConferencePaper (2014)


Polyphenols from Chilean native berries as antiglycating agents submitted to thermal treatment conditions: a contribution to decrease deleterious effects mediated by dietary glycotoxins Avila, Felipe Proyecto (2022)
A metabolomic approach on the health promoting effect of phenolics and saponins from Chilean native beans and squash Schmeda-Hirschmann, Guillermo; THEODULOZ, CRISTINA; Avila, Felipe; DROGUETT, DANIEL Proyecto (2021)
Cape Horn International Center for Global Change Studies and Biocultural Conservation (CHIC) Rozzi, Ricardo Proyecto (2021)
Multidisciplinary studies on bioactive compounds from the Chilean Phaseolus vulgaris L. landraces and their potential effects in the prevention of non-communicable chronic diseases Carrasco, Basilio Alejandro Proyecto (2020)
Phenolic metabolome of Chilean native nuts and seeds: antioxidant activity and inhibitory effect on key enzymes associated with metabolic syndrome. Schmeda-Hirschmann, Guillermo; THEODULOZ, CRISTINA Proyecto (2017)
Metabolomics of Chilean Native Fruits. SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (2012)
Novel hybrid terpene-naphthoquinone gastroprotective compounds: synthesis and assessment of action mechanisms using human cell culture models. Theoduloz, C. Proyecto (2011)
Phenstatin analogues and donor-acceptor naphthoquinones: Synthesis via solar-chemical photo-Friedel-Craft reaction and antitumor evaluation. Valderrama J.A.; Theoduloz, C. Proyecto (2010)
Semisynthesis of new gastroprotective labdane diterpenes: structure-activity relationships. SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (2008)
Estudio del mecanismo gastroprotector de diterpenos naturales y hemisintéticos derivados del ferruginol y carnosol, utilizando modelos animales y cultivo de células epiteliales gástricas humanas. Rodriguez, J.A.; Theoduloz, C. Proyecto (2006)
Antioxidantes, antifúngicos y antiparasitarios de Protousnea poepigii, Tagetes mendocina, Usnea florida y Zucccagnia punctata. SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (2000)
Atrapadores de radicales libres e inhibidores enzimáticos de plantas aromáticas y medicinales sudamericanas. SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (2000)
Actividad insecticida de bacterias modificadas del filoplano del tomate como complemento para el control de la plaga “polilla del tomate”. Meza Basso, L.; Theoduloz, C. Proyecto (1999)
Determinación sexual en la planta dioica Melandrium album. Identificación de genes involucrados en el programa de diferenciación masculino. González, E.; Theoduloz, C. Proyecto (1995)
Caracterización de cepas nativas de Bacillus thuringiensis y optimización de la expresión de los genes codificadores de sus -endotoxinas Meza Basso, L.; Theoduloz, C. Proyecto (1994)
Análisis, comprensión y manipulación de la respuesta de vegetales al estrés ambiental. Meza Basso, L. y Caligari, P.D.S.; Theoduloz, C. Proyecto (1991)
Molecular genetics and breeding for resistance and stress tolerance in potatoes. Meza Basso, L.; Theoduloz, C. Proyecto (1991)
Obtención de plantas transformadas que expresen la -endotoxina de cepas locales de Bacillus thuringiensis. Meza Basso, L.; Theoduloz, C. Proyecto (1991)
Química, actividad biológica y micropropagación de plantas medicinales mapuches. SCHMEDA-HIRSCHMANN, G.; Theoduloz, C. Proyecto (1990)
Resistencia a virosis en papa: desarrollo de plantas resistentes a los virus PVX, PVY, PVS y PLRV mediante técnicas de cultivo in vitro y biología molecular. Meza Basso, L.; Theoduloz, C. Proyecto (1988)
Transformación genética de maíz y caña de azúcar para la obtención de plantas resistentes al ataque de insectos. Luis Meza Basso; Theoduloz, Cristina Proyecto (1988)