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JHON JAIRO LÓPEZ VILLA

Assistant Professor

Universidad de Concepción

Concepción, Chile

• Diseño y síntesis de ligandos bioactivos para el receptor nicotínico de acetilcolina (RnACo). • Estudios de simulación molecular del RnACo.

Magister en Química, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2013
Doctor en Química, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2016
Químico, UNIVERSIDAD DE CORDOBA. Colombia, 2006

Docente de Química Part Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Química y Farmacia

Santiago, Chile

2015 - 2018

Docente de Química y Biología Full Time

Colegio el Hogar

Cali, Colombia

2008 - 2010
Docente de Química Part Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2015 - 2018
Profesor Asistente Full Time

Universidad de Concepción

Concepción, Chile

2018 - At present
Postdoctorado Other

Universidad de Chile

Santiago, Chile

2017 - 2018
Postdoctorado Other

Universidad de Concepción

Concepción, Chile

2019 - 2020


New convergent one pot synthesis of amino benzyl ethers bearing a nitrogen-containing bicycle LÃ³pez J.J.; PÃ©rez E.G. Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2019)
Methylpiperidinium Iodides as Novel Antagonists for alpha 7 Nicotinic Acetylcholine Receptors Lopez, JJ; Garcia-Colunga, J; Perez, EG; Fierro, A Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2018)
Copper-Catalyzed Intermolecular Aminooxygenation of Styrenes using N-Fluorobenzenesulfonimide and Simple Alcohols Herrera-Leyton C.; Madrid-Rojas, M; López J.J.; Cañete Á.; Hermosilla-Ibáñez P; Pérez E.G. Article ISI SCOPUS CHEMCATCHEM (2016)
Copper-catalyzed intermolecular and regioselective aminofluorination of styrenes: facile access to beta-fluoro-N-protected phenethylamines Saavedra-Olavarria, J; Arteaga G.C.; López J.J.; Pérez E.G. Article ISI SCOPUS CHEMICAL COMMUNICATIONS (2015)
Dual effects of a 2-benzylquinuclidinium derivative on alpha 7-containing nicotinic acetylcholine receptors in rat hippocampal interneurons Lopez, JJ; Perez, EG.; Garcia-Colunga, J Article ISI SCOPUS Neuroscience Letters (2015)
Gramicidin conformational changes during riboflavin photosensitized oxidation in solution and the effect of N-methylation of tryptophan residues Fuentealba, D; Lopez, JJ; Palominos, M; Salas, CO; Soto-Arriaza, MA Article ISI SCOPUS Photochemical and Photobiological Sciences (2015)
The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of alpha 7 Nicotinic Acetylcholine Receptors in Mice Bagdas, D; Targowska-Duda, KM; Lopez, JJ; Perez, EG.; Arias, HR; Damaj, MI Article ISI ANESTHESIA AND ANALGESIA (2015)
Novel 1-(1-benzyl-1H-indol-3-yl)-N,N,N-trimethylmethanaminium iodides are competitive antagonists for the human alpha 4 beta 2 and alpha 7 nicotinic acetylcholine receptors Perez, EG.; Ocampo, C; Feuerbach D.; Lopez, JJ; Morelo, GL; Tapia, RA; Arias, HR Article ISI SCOPUS MedChemComm (2013)
Novel 2-(substituted benzyl)quinuclidines inhibit human alpha 7 and alpha 4 beta 2 nicotinic receptors by different mechanisms Arias, HR; Lopez, JJ; Feuerbach D.; Fierro, A.; Ortells, MO; Perez, EG. Article ISI SCOPUS International Journal of Biochemistry and Cell Biology (2013)


DISEÑO Y SÍNTESIS DE LIGANDOS DIRIGIDOS A UN NUEVO RECEPTOR NICOTÍNICO DE ACETILCOLINA (RNACO) HETEROMÉRICO ALFA7BETA2 López Jhon Jairo Proyecto (2017)
Insecticidas de nueva generación Fundación Copec-UC (R.2013.33) Proyecto 2014-2017 Personal técnico y/o de apoyo
Design, synthesis and evaluation of possible selective agonists of alpha9 and alpha9alpha10 nicotinic acetylcholine receptor subtypes. FONDECYT (1130079) Proyecto 2013-2016 Tesista
"DESIGN, SYNTHESIS AND EVALUATION OF POSSIBLE SUBTYPE-SELECTIVE ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS" FONDECYT (11090120) Proyecto 2010-2012 Tesista