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Efrain Andres Polo Cuadrado

Docente

Universidad de Talca

Talca, Chile

Sintesis y bioactividad de pirazolopiridinas Diseño y sintesis de Biomateriales para la liberacion controlada de farmacos

Quimica Organica, UNIVERSIDAD DE TALCA. Chile, 2020
Quimico, Universidad del Atlantico. Colombia, 2012

Docente de Laboratorio Part Time

Universidad de Talca

Talca, Chile

2013 - 2013
Tutor academico- Programa CIVE Full Time

Universidad de Talca

Chile

2018 - At present
Profesor Asistente Full Time

Universidad de Concepcion

Concepcion, Chile

2024 - At present


Crystal structure, quantum chemical insights, and molecular docking studies of <i>N</i>aryl-2-(<i>N</i>-<sub>disubstituted</sub>) acetamide compounds: potential inhibitors for neurodegenerative enzymes Camargo-Ayala, Lorena; Bedoya, Mauricio; Prent-Penaloza, Luis; Polo-Cuadrado, Efrain; Osorio, Edison; Brito, Ivan; Delgado, Gerzon E.; Gonzalez, Wendy; Gutierrez, Margarita Article ISI RSC ADVANCES (2024)
Nonlinear optical and spectroscopic properties, thermal analysis, and hemolytic capacity evaluation of quinoline-1,3-benzodioxole chalcone Polo-Cuadrado, Efrain; Osorio, Edison; Acosta-Quiroga, Karen; Camargo-Ayala, Paola Andrea; Brito, Ivan; Rodriguez, Jany; Alderete, Joel B.; Forero-Doria, Oscar; Blanco-Acuna, Edgard Fabian; Gutierrez, Margarita Article ISI RSC ADVANCES (2024)
Comprehensive analysis of crystal structure, spectroscopic properties, quantum chemical insights, and molecular docking studies of two pyrazolopyridine compounds: potential anticancer agents Polo-Cuadrado, Efrain; Lopez-Cuellar, Lorena; Acosta-Quiroga, Karen; Rojas-Pena, Cristian; Brito, Ivan; Cisterna, Jonathan; Trilleras, Jorge; Alderete, Joel B.; Duarte, Yorley; Gutierrez, Margarita Article ISI RSC ADVANCES (2023)
Piperonal chalcone derivative incorporating the pyrazolo[3,4-b]pyridine moiety; crystal structure, spectroscopic characterization and quantum chemical investigations Polo-Cuadrado, Efrain; Ferrer, Karoll; Osorio, Edison; Brito, Ivan; Cisterna, Jonathan; Espinoza, Luis; Alderete, Joel B.; Gutierrez, Margarita Article ISI RSC ADVANCES (2023)
Design, synthesis, theoretical study, antioxidant, and anticholinesterase activities of new pyrazolo-fused phenanthrolines Polo-Cuadrado, Efrain; Rojas-Pena, Cristian; Acosta-Quiroga, Karen; Camargo-Ayala, Lorena; Brito, Ivan; Cisterna, Jonathan; Moncada, Felix; Trilleras, Jorge; Rodriguez-Nunez, Yeray A.; Gutierrez, Margarita Article ISI RSC ADVANCES (2022)
Molecular modeling and structural analysis of some tetrahydroindazole and cyclopentanepyrazole derivatives as COX-2 inhibitors Polo-Cuadrado, Efrain; Acosta-Quiroga, Karen; Rojas-Pena, Cristian; Rodriguez-Nunez, Yeray A.; Duarte, Yorley; Brito, Ivan; Cisterna, Jonathan; Gutierrez, Margarita Article ISI ARABIAN JOURNAL OF CHEMISTRY (2022)
Single crystal structure, thermal stability and theoretical studies of ethyl 4-(4-(dimethylamino)phenyl)-3,6-dimethyl-1-phenyl-1 H-pyrazolo[3,4-b ]pyridine-5-carboxylate Polo-Cuadrado, Efrain; Ferrer, Karoll; Forero-Doria, Oscar; Morales-Bayuelo, Alejandro; Brito, Ivan; Cisterna, Jonathan; Espinoza, Luis; Sanchez-Marquez, Jesus; Gutierrez, Margarita Article ISI JOURNAL OF MOLECULAR STRUCTURE (2022)
Synthesis multicomponent based on o-tolyl-isocyanide; cholinesterase inhibitors and computational studies Camargo-Ayala, Lorena; Polo-Cuadrado, Efrain; Osorio, Edison; Soto-Delgado, Jorge; Duarte, Yorley; Prent-Penaloza, Luis; Gutierrez, Margarita Article ISI JOURNAL OF MOLECULAR STRUCTURE (2022)
Synthesis, characterization, crystal and molecular structure and theoretical study of N-(naphthalen-1-yl)-2-(piperidin-1-yl) acetamide, a selective butyrylcholinesterase inhibitor Camargo-Ayala, Lorena; Prent-Penaloza, Luis; Polo-Cuadrado, Efrain; Ivan, Brito; Cisterna, Jonathan; Osorio, Edison; Gonzalez, Wendy; Gutierrez, Margarita Article ISI JOURNAL OF MOLECULAR STRUCTURE (2022)
Antimicrobial properties of novel ionic liquids derived from imidazolium cation with phenolic functional groups Guzman, Luis; Parra-Cid, Cristobal; Guerrero-Munoz, Etiennette; Pena-Varas, Carlos; Polo-Cuadrado, Efrain; Duarte, Yorley; Castro, Ricardo I.; Nerio, Luz Stella; Araya-Maturana, Ramiro; Asefa, Tewodros; Echeverria, Javier; Ramirez, David; Forero-Doria, Oscar Article ISI BIOORGANIC CHEMISTRY (2021)
Crystal structure, Hirshfeld surface analysis and DFT studies of <i>N</i>-(4-acetylphenyl)quinoline-3-carboxamide Polo-Cuadrado, Efrain; Ferrer, Karoll; Osorio, Edison; Brito, Ivan; Cisterna, Jonathan; Gutierrez, Margarita Article ISI JOURNAL OF MOLECULAR STRUCTURE (2021)
Microwave-assisted synthesis, biological assessment, and molecular modeling of aza-heterocycles: Potential inhibitory capacity of cholinergic enzymes to Alzheimer's disease Polo, Efraín Article JOURNAL OF MOLECULAR STRUCTURE (2021)
Use of Poly(vinyl alcohol)-Malic Acid (CLHPMA) Hydrogels and Chitosan Coated Calcium Alginate (CCCA) Microparticles as Potential Sorbent Phases for the Extraction and Quantitative Determination of Pesticides from Aqueous Solutions Valdes, Cristian; Valdes, Oscar; Bustos, Daniel; Abril, Diana; Cabrera-Barjas, Gustavo; Pereira, Alfredo; Villasenor, Jorge; Polo-Cuadrado, Efrain; Carreno, Gustavo; Duran-Lara, Esteban F.; Marican, Adolfo Article ISI POLYMERS (2021)
Data of preparation and evaluation of supramolecular hydrogel based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties Polo, Efrain Article DATA IN BRIEF (2020)
Supramolecular hydrogels based on cellulose for sustained release of therapeutic substances with antimicrobial and wound healing properties Polo, Efrain Article CARBOHYDRATE POLYMERS (2020)
Crystal structure and theoretical studies of 2-bromo-N-(2,4-difluorobenzyl)benzamide; intermediate for the synthesis of phenanthridinone Polo, Efraín; Morales-Bayuelo, Alejandro; Orozco-Ugarriza, Mauricio E.; Henao, José A.; Galdámez, Antonio; Gutierrez, Margarita Article SCOPUS Chemical Data Collections (2019)
Synthesis of Pyrazolo-Fused 4-Azafluorenones in an Ionic Liquid. Mechanistic Insights by Joint Studies Using DFT Analysis and Mass Spectrometry Polo, Efrain; Arce-Parada, Valentina; Lopez-Cortes, Xaviera A.; Sanchez-Marquez, Jesus; Morales-Bayuelo, Alejandro; Forero-Doria, Oscar; Gutierrez, Margarita Article ISI SCOPUS CATALYSTS (2019)
Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors Polo, Efraín; Ibarra-Arellano, Nicol; Prent-Peñaloza, Luis; Morales-Bayuelo, Alejandro; Henao, José; Galdámez, Antonio; Gutiérrez, Margarita Article ISI SCOPUS BIOORGANIC CHEMISTRY (2019)
Microwave-assisted one-pot synthesis in water of carbonylpyrazolo[3,4-b] pyridine derivatives catalyzed by InCl3 and sonochemical assisted condensation with aldehydes to obtain new chalcone derivatives containing the pyrazolopyridinic moiety Polo, E; Ferrer-Pertuz, K; Trilleras, J; Quiroga, J; Gutierrez, M Article ISI SCOPUS JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2017)
N-{4-[(2E)-3-(2H-1,3-Benzodioxol-5-yl)prop-2-enoyl]phenyl}quinoline-3-carboxamide Polo, E; Trilleras, J; Cabrera, MG Article WOS-ESCI SCOPUS MolBank (2017)
Efficient MW-Assisted Synthesis, Spectroscopic Characterization, X-ray and Antioxidant Properties of Indazole Derivatives Polo, E; Trilleras, J; Ramos, J; Galdamez, A; Quiroga, J; Gutierrez, M Article ISI SCOPUS MOLECULES (2016)
Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives Polo, Efrain Article APPLIED SCIENCES-BASEL (2013)


Spirocyclic derivatives as antioxidants: a review Acosta-Quiroga, Karen; Rojas-Pena, Cristian; Nerio, Luz Stella; Gutierrez, Margarita; Polo-Cuadrado, Efrain Review ISI RSC ADVANCES (2021)