Computer-Aided Drug Design, Bioinformatics, Biophysics of potassium channels, Molecular Dynamics simulations, Molecular Modeling, Protein-ligand interactions, Machine Learning

Direction of undergraduate theses:

I)
Student: Enzo Tomás Viera Fica
Thesis title: Comparative molecular study of the nitrate and auxin binding sites present in the NRT1.1 transceiver
Year: 2015
Career / University: Bioinformatics Engineering / University of Talca.

II)
Student: Maira Vidal Valenzuela
Thesis title: Prediction of protonation states in proteins by molecular modeling
Year: 2021
Career / University: Biotechnology Engineering / Universidad Católica del Maule.

III)
Student: Paulina Valenzuela Hormazabal
Thesis title: Implementación de una estrategia basada en métodos teórico-computacionales para la búsqueda de nuevos inhibidores en la enzima ureasa de Helicobacter pylori
Year: 2022
Career / University: Bioinformatics Engineering / Universidad Católica del Maule.

IV)
Student: Gabriela Urra Gajardo
Thesis title: Reposicionamiento de fármacos y proteómica sustractiva en Pseudomonas aeruginosa
Year: 2022-2023
Career / University: Biotechnology Engineering / Universidad Católica del Maule.

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Direction of Master theses:

I)
Student: Natalia Morales Rosales
Thesis title: Propiedades fisicoquímicas utilizadas como criterios de filtrado para construir clasificadores basados en algoritmos de aprendizaje automático: inhibidores de ureasa como caso de estudio
Year: 2021-2022
Program / University: Magíster en Ciencias de la Computación / Universidad Católica del Maule.

II)
Student: Jaime González Díaz
Thesis title: Reposicionamiento de Drogas en el Canal Iónico TRPV1 Mediante un Enfoque Computacional
Year: 2021-2022
Program / University: Magíster en Ciencias de la Computación / Universidad Católica del Maule.

III)
Student: Verónica Leddermann Gutiérrez
Thesis title: Implementación de diferentes estrategias de funciones multiparámetros aplicados al diseño de fármacos.
Year: 2022-2023
Program / University: Magíster en Ciencias de la Computación / Universidad Católica del Maule.

VI)
Student: Camila Flores Morales
Thesis title: Análisis del espacio químico de los inhibidores en proteínas escenciales para la sobrevivencia de Helicobacter pylori.
Year: 2022-2023
Program / University: Magíster en Ciencias de la Computación / Universidad Católica del Maule.

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Direction of PhD. theses:

Student: Elizabeth Valdés Muñoz
Thesis title: Diseño de fármacos antimicrobianos
Year: 2022-2025
Program / University: Doctorado en Biotecnología Traslacional / Universidad Católica del Maule.

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Professional practices:

I)
Student: Paulina Valenzuela Hormazabal
Practice title: Structural characterization of coumarins with inhibitory potential in Helicobacter pylori ureases
Year: 2021
Career / University: Bioinformatics Engineering / Universidad Católica del Maule

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Thesis evaluation:

I)
Student: Javier Riquelme Pizarro
Master's thesis title: Efficient kNN query processing on a multi-node / multi-GPU platform
Years: 2021
Program / University: Master in Computer Science / Universidad Católica del Maule.

I) Co-creation of the Bioinformatics and Computational Chemistry Laboratory (Laboratorio de Bioinformática y Química Computacional, LBQC), Facultad de Medicina, Universidad Católica del Maule.

II) Participation as an expert consulted in the field of Bioinformatics for the creation of the Medical Bioengineering career, as well as the contribution to the formation of thematic programs and contents of the courses of Mathematics and Computing I and II, Biophysics, Bioinformatics and Artificial Intelligence.

III) Oral presentation at the First Online Symposium on Bionformatics at the Universidad Católica del Maule, Talca, Chile, 2020.

IV) Presentation at the Society for Biochemistry and Molecular Biology of Chile, Iquique, Chile, 2018.

V) Organizer and speaker of the cycle of talks "Ciencias computacionales al servicio de problemáticas en química medicinal y ambiental"