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David Antonio Pezoa Aros

Académico Investigador

Universida de las Américas

Santiago, Chile

Sistemas de secreción tipo VI (T6SS) en Salmonella enterica. Resistencia Antimicrobiana en el contexto Una Salud.

Medicina Veterinaria, UNIVERSIDAD DE CHILE. Chile, 2010
Microbiología, UNIVERSIDAD DE CHILE. Chile, 2014
Licenciatura en Medicina Veterinaria, UNIVERSIDAD DE CHILE. Chile, 2006

Profesor Asociado Part Time

UNIVERSIDAD BERNARDO O'HIGGINS

2014 - A la fecha
Académico Investigador Full Time

Universidad de Las Américas

Facultad de Medicina Veterinaria y Agronomía

Santiago, Chile

2022 - A la fecha
Académico Regular Full Time

Universidad Mayor

Facultad de Medicina Veterinaria

Santiago, Chile

2018 - 2022

Tesista de pregrado

UNIVERSIDAD DE CHILE

Chile

2007 - 2008
Ayudante

UNIVERSIDAD DE CHILE

Chile

2003 - 2003
Estudiante de Doctorado en Unidad de Investigación

UNIVERSIDAD DE CHILE

Chile

2009 - 2010
Investigador en Visita (Pasantía Doctoral)

Texas A&M University

Estados Unidos

2011 - 2012
Monitor

UNIVERSIDAD DE CHILE

Chile

2003 - 2007
Docente Biología

Universidad Bernardo Ohiggins

Chile

2014 - A la fecha
Docente Microbiología

Universidad Bernardo Ohiggins

Chile

2014 - A la fecha
Profesor Unidad F-16 "Agentes Biológicos"

Universidad de Chile

Chile

2013 - 2013
Docente Fisiopatología

Universidad Bernardo Ohiggins

Chile

2015 - A la fecha
Docente Histoembriologìa

Universidad Bernardo Ohiggins

Chile

2015 - A la fecha
Docente Biología y Patología Molecular

Universidad Andrés Bello

Chile

2014 - 2015
Fulbright Fellow/Alumni

Texas A&M University

Estados Unidos

2012 - A la fecha

2010-2012 Tutor-guia de tesillas de “Microbiologia II”, carrera de Bioqui?mica Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile

2014-2015 Disen?o de una formulacio?n para uso farmace?utico efectiva para bacterias Fondef-Idea CA12I10110. Investigador asociado
2011-2013 Type Six Secretion Systems in Salmonella enterica: Role in pathogenicity and host specificity of serotypes Typhimurium, Dublin, Gallinarum and Enteritidis. Fondecyt 1100092. Universidad de Chile.
2011-2012 Research stay at Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A&M University System Health Science Center, College Station, Texas, USA. Under the supervision of Dr. Helene Andrews-Polymenis. Fulbright Fellowship
2008. Asistente de investigación. Bu?squeda de protei?nas que interactu?an con la Glutamil-tRNA reductasa en Acidithiobacillus ferrooxidans. Fondecyt 1070437

Premio al Me?rito Docente

UNIVERSIDAD BERNARDO O'HIGGINS

Chile, 2015

Premio docente
Beca de asistencia a curso de bioinformatica “Working with pathogen genomes” Montevideo, Uruguay

WELLCOME TRUST SANGER INSTITUTE

Uruguay, 2013

Curso de bioinformatica
Beca Termino de tesis

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2013

Becas para terminar la tesis doctoral
Beca de asistencia a congresos y eventos

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2012

Beca de asistencia a congresos y eventos
Beca de apoyo a la realizacio?n de tesis doctoral

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2013

Beca para realizar tesis doctoral
Comisio?n Fulbright para el intercambio educativo entre Chile y los Estados Unidos de Ame?rica

COMISION FULBRIGHT-CHILE

Chile, 2012

Intercambio
FULBRIGHT Fellowship for a Research Stay in USA

COMISION FULBRIGHT-CHILE

Estados Unidos, 2012

FULBRIGHT Fellowship for a Research Stay in USA
Beca CHILE de Pasanti?as Doctorales en el extranjero

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2012

Beca CHILE de Pasanti?as
Beca CONICYT para estudios de Doctorado en Chile

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2009

BECA DOCTORADO NACIONAL


Genomic analysis of Salmonella isolated from surface water and animal sources in Chile reveals new T6SS effector protein candidates Blondel, Carlos J.; Reyes-Mendez, Felipe; Toro, Magaly; Badilla, Consuelo; Santiviago, Carlos A. Article ISI FRONTIERS IN MICROBIOLOGY (2024)
Identification and distribution of new candidate T6SS effectors encoded in <i>Salmonella</i> Pathogenicity Island 6 Blondel, Carlos J.; Amaya, Fernando A.; Bustamante, Paloma; Santiviago, Carlos A.; Pezoa, David Article ISI FRONTIERS IN MICROBIOLOGY (2023)
Transfer of T6SS<sub>SPI-19</sub> from <i>Salmonella Gallinarum</i> to Salmonella Typhimurium Lacking T6SS<sub>SPI-6</sub> Complements its Colonization Defect in Mice Blondel, Carlos J. J.; Amaya, Fernando A. A.; Santiviago, Carlos A. A. Article ISI POLISH JOURNAL OF MICROBIOLOGY (2023)
Identification of Type VI Secretion Systems Effector Proteins That Contribute to Interbacterial Competition in Salmonella Dublin Amaya, Fernando A.; Blondel, Carlos J.; Barros-Infante, Maria F.; Santiviago, Carlos A. Article ISI FRONTIERS IN MICROBIOLOGY (2022)
Transduction as a Potential Dissemination Mechanism of a Clonal qnrB19-Carrying Plasmid Isolated From Salmonella of Multiple Serotypes and Isolation Sources Pezoa, David; Sepulveda, Vanessa; Reyes-Jara, Angelica; Toro, Magaly Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2019)
Two Phages of the Genera Felixunavirus Subjected to 12 Hour Challenge on Salmonella Infantis Showed Distinct Genotypic and Phenotypic Changes Hudson L.K.; Denes T.G. Article ISI SCOPUS VIRUSES-BASEL (2019)
Solid tumors provide niche- specific conditions that lead to preferential growth of Salmonella Cecilia Silva, Prerak Desai, Roberto Molina-Quiroz, David Pezoa , Yong Zhang, Steffen Porwollik Ming Zhao, Robert Hoffman, Ines Contreras, Carlos Santiviago, Michael McClelland Article ONCOTARGET (2016)
Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella Pezoa, D; Zhang, Y; Porwollik, S; Zhao, M; Contreras, I; Santiviago, C. A.; McClelland, M Article ISI SCOPUS ONCOTARGET (2016)
Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts Pezoa, D; Blondel CJ; Yang, HJ; Andrews-Polymenis, H; Santiviago, CA; Contreras, I Article ISI SCOPUS VETERINARY RESEARCH (2014)
The Type VI Secretion System Encoded in Salmonella Pathogenicity Island 19 Is Required for Salmonella enterica Serotype Gallinarum Survival within Infected Macrophages Blondel CJ; Jiménez, JC; Leiva, LE; Pinto, BI; Contreras F.; Pezoa, D; Santiviago, CA; Contreras, I Article ISI SCOPUS INFECTION AND IMMUNITY (2013)
The Type VI Secretion System Encoded in SPI-6 Plays a Role in Gastrointestinal Colonization and Systemic Spread of Salmonella enterica serovar Typhimurium in the Chicken Pezoa, D; Yang, HJ; Blondel CJ; Santiviago, CA; Andrews-Polymenis, HL; Contreras, I Article ISI SCOPUS PLOS ONE (2013)


The type VI secretion systems encoded in Salmonella pathogenicity islands SPI-6 and SPI-19 contribute to intestinal colonization of chickens and systemic spread by Salmonella enterica serotype Typhimurium Pezoa, D; Andrews-Polymenis, H; Blondel CJ; Leiva, L; Pinto, B.; Santiviago, CA; Contreras, LI Abstract ISI FEBS JOURNAL (2012)


“Contribution of the T6SSs encoded in SPI-6 and SPI-19 to Salmonella pathogenesis and the development of strategies to search for hypersecretion effector mutants”. C.J. Blondel, D. Pezoa, H. Yang, C.A. Silva, C. Valenzuela, H. Andrews-Polymenis, C.A. Santiviago, I. Contreras. ConferencePoster (2013)
“Contribution of type VI secretion systems to virulence of Salmonella enterica”. David Pezoa, Hee-Jeong Yang, Carlos J. Blondel, Helene Andrews-Polymenis, Carlos A. Santiviago, Luci?a I. Contreras. ConferencePoster (2013)
“Identification of novel genes involved in S. Typhimurium systemic colonization of Balb/c mice”. Cecilia A. Silva, P. Cheng. C.J. Blondel, D. Pezoa, R. Molina-Quiroz, M. Zhao, Y. Zhang, P. Desai, S. Porwollik, R. Hoffman, H. Andrews-Polymenis, I. Contreras, C.A. Santiviago, M. ConferencePoster (2013)
“Salmonella Gallinarum utilizes a type VI secretion system to survive within avian and murine macrophages”. C.J. Blondel, J.C. Jime?nez, L.E. Leiva, S.A. A?lvarez, B.I. Pinto, F. Contreras, D. Pezoa, C.A. Santiviago, I. Contreras. ConferencePoster (2013)
“The type VI secretion systems encoded in Salmonella pathogenesis islands SPI-6 and SPI-19 contribute to intestinal colonization of chickens and systemic spread by Salmonella enterica serotype Typhimurium”. David Pezoa, Helene Andrews-Polymenis, Carlos J.Blondel, Lorenzo Leiva, Bernardo Pinto, Sergio A. Alvarez, Carlos A. Santiviago, Luci?a Ine?s Contreras. ConferencePoster (2012)


The Type VI Secretion System Encoded in Salmonella Pathogenicity Island 19 Is Required for Salmonella enterica Serotype Gallinarum Survival within Infected Macrophages (vol 81, pg 1207, 2013) Blondel CJ; Jiménez, JC; Leiva, LE; Pinto, BI; Contreras F.; Pezoa, D; Santiviago, CA; Contreras, I Errata ISI SCOPUS Infection and Immunity (2015)


Functional and biochemical characterization of a putative antibacterial type VI secretion system effector of the foodborne pathogen Salmonella Dublin DAVID ANTONIO PEZOA AROS Proyecto (2024)
Collaborative initiative for the functional characterization of novel components of The Type Six Secretion System (T6SS)of the foodborne pathogen Campylobacter jejuni Blondel, Carlos; DAVID ANTONIO PEZOA AROS Proyecto (2020)
Desarrollo de un modelo agroecológico para el control de la coccidiosis aviar y creación de una red de innovación para su implementación en la agricultura familiar Anabel Rodriguez; Pezoa, David Proyecto (2020)
Diseño de una formulación para uso farmacéutico efectiva para bacterias multirresistentes de importancia médica FONDEF (CA12I10110) Proyecto 2012-2014 Personal técnico y/o de apoyo
Type Six Secretion Systems in Salmonella enterica=> Role in pathogenicity and host specificity of serotypes Typhimurium, Dublin, Gallinarum and Enteritidis FONDECYT (1100092) Proyecto 2010-2012 Tesista
PARTICIPACION DE LAS GLUTAMIL-tRNA SINTETASAS EN FUNCIONES ALTERNATIVAS A LA BIOSINTESIS DE PROTEINAS=> BIOSINTESIS DE TETRAPIRROLES Y/O GLUTAMINA. FONDECYT (1070437) Proyecto 2007-2011 Tesista


Deciphering the Salmonella T6SS toolkit: two decades of research decoding a versatile bacterial weapon Blondel, Carlos J.; Amaya, Fernando A.; Reyes-Mendez, Felipe; Soriano-Mora, Victoria; Vargas, Carla; Parra, Ayleen; Opazo, Maria C.; Toledo, Viviana; Barros-Infante, Maria F.; Santiviago, Carlos A.; et al. Review ISI JOURNAL OF BACTERIOLOGY (2025)