Man

Miguel Ignacio del Campo Zaldívar

Investigador Adjunto Proyecto FONDECYT 151337

Fundación Ciencia y Tecnología para el Desarrollo

Santiago, Chile

Líneas de Investigación


Bioquímica; Compuestos naturales; Toxicología

Educación

  •  Doctorado en Bioquímica, UNIVERSIDAD DE CHILE. Chile, 2014
  •  Bioquímico , UNIVERSIDAD DE CHILE. Chile, 2007

Experiencia Académica

  •   Alumno doctoral Full Time

    UNIVERSIDAD DE CHILE

    2011 - 2014

Experiencia Profesional

  •   Investigador Adjunto Proyecto Fondecyt 105-0150

    Biosonda S.A

    Chile

    2006 - 2009

  •   Investigador Adjunto Proyecto COPEC-PUCSC0014

    Fundación Ciencia y Tecnología para el Desarrollo

    Chile

    2008 - 2010

  •   Investigador Adjunto Proyecto Fondecyt 1110651

    Fundación Ciencia y Tecnología para el Desarrollo

    Chile

    2014 - 2014

  •   Investigador Adjunto Proyecto FONDECYT 151337

    Fundación Ciencia y Tecnología para el Desarrollo

    Chile

    2015 - A la fecha

  •   Investigador Adjunto Proyecto INNOVA 13IDL2-18697

    Fundación Ciencia y Tecnología para el Desarrollo

    Chile

    2014 - A la fecha


 

Article (23)

C-type lectin receptors MR and DC-SIGN are involved in recognition of hemocyanins, shaping their immunostimulatory effects on human dendritic cells
Nerve Growth Factor: A Dual Activator of Noradrenergic and Cholinergic Systems of the Rat Ovary
In vivo blockade of ovarian sympathetic activity by Neosaxitoxin prevents polycystic ovary in rats
Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages
Effect of Superior Ovarian Nerve and Plexus Nerve Sympathetic Denervation on Ovarian-Derived Infertility Provoked by Estradiol Exposure to Rats
Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer.
Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer.
Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside
Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model
Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model.
Sublethal doses of dinophysistoxin-1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells=> Negative health consequences.
The oxygen-binding properties of hemocyanin from the mollusk Concholepas concholepas.
Antibacterial effect of kaempferol and (?)-epicatechin on Helicobacter pylori
Determination of the toxic variability of lipophilic biotoxins in marine bivalve and gastropod tissues treated with an industrial canning process.
Gonyautoxins: First evidence in pain management in total knee arthroplasty
Hemocyanins stimulate innate immunity by inducing different temporal patterns of proinflammatory cytokine expression in macrophages
A Novel Immunomodulatory Hemocyanin from the Limpet Fissurella latimarginata Promotes Potent Anti-Tumor Activity in Melanoma
Okadaic Acid Toxin at Sublethal Dose Produced Cell Proliferation in Gastric and Colon Epithelial Cell Lines
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects
Hemocyanins as immunostimulants
Hemocyanins as immunostimulants Hemocianinas, una herramienta inmunológica de la biomedicina actual
Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism
Immunodominant role of CCHA subunit of Concholepas hemocyanin is associated with unique biochemical properties

Abstract (4)

Novel hemocyanin from the Fissurella latimarginata exhibits an outstanding immunogenicity and non-specific immunomodulatory effects in a melanoma model
Exceptional Immunological and Anticancer Properties of a New Hemocyanin from Fissurella Latimarginata (FLH)
Antitumor Effect of Concholepas Concholepas Hemocyanin (CCH) Using B16-F10 Mouse Melanoma Cells as a Model
Biochemical and Immunomodulatory Properties From Concholepas Hemocyanin (CCH) and Their Isolated Subunits

Proyecto (9)

AUTONOMIC NEURAL CONTROL OF OVARY FUNCTION. PARTICIPATION IN THE POLYCYSTIC OVARY DEVELOPMENT AND FERTILITY.
Prototype development of an enzymatic inhibition assay of Protein Phosphatase 2A for detection and quantification of diarrhetic toxins in fresh and canned extracts shellfish
Mollusk hemocyanins as immunomodulatory proteins with beneficial clinical outcomes=> Elucidating the role of C-type lectin receptors in these effects.
Diarrheic shellfish toxins=> biochemical and toxicological mechanism as tumor promoters
Identificación de péptidos antimicrobianos desde moluscos litorales chilenos y potencial uso biotecnológico
DOCTORADO EN BIOQUIMICA
Immunological basis involved in the immunomodulatory effects of mollusk hemocyanins in the immune system of mammals
ESTUDIO DE LA ESTRUCTURA DE LA HEMOCIANINA DE MOLUSCOS EN RELACION A SUS MECANISMOS DE INMUNOESTIMULACION EN MAMIFEROS.
Desarrollo de productos inmunoestimulantes en base a hemocianinas de C. concholepas.
20
Miguel del Campo

Investigador Adjunto Proyecto FONDECYT 151337

Fundación Ciencia y Tecnología para el Desarrollo

Santiago, Chile

11
María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

10
Augusto Manubens

Director

Tecnical Support

BIOSONDA S.A.

Santiago, Chile

6
Fabian Salazar

Postdoctoral Research Fellow

Biosciences

MRC Centre for Medical Mycology, University of Exeter

Exeter, Reino Unido

6
Sergio Arancibia

Medical Science Liaison

Medical Affairs

Johnson & Johnson (Janssen Pharmaceutical)

Santiago, Chile

5
Pablo De Ioannes

Associate research scientist

Structural Biology

NYU Medical Center

NEW YORK, Estados Unidos

3
Nestor Lagos

Full Professor

Fisiología y Biofísica

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

SANTIAGO, Chile

2
Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

1
Matias Guerra

Investigador

Banco de recursos Genéticos Microbianos

INIA Quilamapu

Chillan, Chile

1
Julia Guerrero

académico

Programa Disciplinario Fisiologia y Biofisica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
Tamara Bustamante

Asistente de Investigación

Fisiología y Biofísica

Facultad de Medicina Universidad de Chile

Santiago, Chile

1
Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Eric Tapia

Investigador

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1
Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

1
Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Fernando Faunes

Profesor Asistente

Universidad Andrés Bello

Viña del Mar, Chile

1
Jaime Hinzpeter

Staff Departamento

Ortopedia y Traumatología

Hospital Clínico U. de Chile

Santiago, Chile

1
Héctor Venegas

Profesor Titular asociado al Centro

Universidad Diego Portales

Santiago, Chile

1
Jaime Figueroa

Profesor Titular

Bioquimica y Microbiologia

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Denise Haussmann

Profesora Titular

Departamento de Ciencias Básicas

Universidad Santo Tomás

Valdivia, Chile

1
María Gleisner

INVESTIGADORA

ICBM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile