Man

Jaime Eugenio Figueroa Valverde

Profesor Titular

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Líneas de Investigación


Molecular Biology of Fish; Fish immunology; Genomics of salmonid bacterial pathogens; Effect of the environment on gene expression (Endocrinology).

Educación

  •  Biologia, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1980
  •  Biologia Molecular, UNIVERSIDAD DE CHILE. Chile, 1985
  •  Biologia celular y Molecular, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1995

Experiencia Académica

  •   Profesor Titular Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Ciencias

    Valdivia, Chile

    1990 - A la fecha

Experiencia Profesional

  •   Becario DAAD en programa de doctorado

    Universidad de Hamburgo

    Alemania

    1988 - 1990

  •   Profesor Titular Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    1990 - A la fecha

Formación de Capital Humano


Direccion de tesis de Pregrado (32)
Direccion de tesis de Postgrado (12)
Direccion de Postdoctorados (2)


Premios y Distinciones

  •   Beca Doctorado en Alemania

    Beca DAAD

    Alemania, 1987

    beca del DAAD (Servicio aleman de intercambio academico) para realizar programa de doctorado en Alemania. Beca sandwich, tesis en Alemania, grado academico entregado por universidad Austral de Chile.


 

Article (60)

BIOINFORMATIC ANALYSIS OF GENOMIC ISLANDS IN WHOLE GENOMES OF PISCIRICKETTSIA SALMONIS STRAINS
Ongoing diversification of the global fish pathogen Piscirickettsia salmonis through genetic isolation and transposition bursts
Proteomic and toxicological analysis of the response of dinoflagellate Alexandrium catenella to changes in NaNO3 concentration
Health Status of Mytilus chilensis from Intensive Culture Areas in Chile Assessed by Molecular, Microbiological, and Histological Analyses
Mytilus chilensis from intensive culture areas in Chile assessed by molecular, microbiological, and histological analyses.
Analysis of genes encoding for proteolytic enzymes and cytotoxic proteins as virulence factors of Piscirickettsia salmonis in SHK-1 cells
characterization of the gut microbiome associated with Mytilus chilensis collected at a mussel farm and from a natural environment in Chile
Development of a Multiplex PCR Assay for Genotyping the Fish Pathogen Piscirickettsia salmonis Through Comparative Genomics
Full recombinant flagellin B from Vibrio anguillarum (rFLA) and its recombinant D1 domain (rND1) promote a pro-inflammatory state and improve vaccination against P. salmonis in Atlantic salmon (S. salar)
Protein-Based Vaccine Protect Against Piscirickettsia salmonis in Atlantic Salmon (Salmo salar)
Biochemical and Genomic Characterization of the Cypermethrin-Degrading and Biosurfactant-Producing Bacterial Strains Isolated from Marine Sediments of the Chilean Northern Patagonia
Biofilm Produced In Vitro by Piscirickettsia salmonis Generates Differential Cytotoxicity Levels and Expression Patterns of Immune Genes in the Atlantic Salmon Cell Line SHK-1
Prolactin peptide (pPRL) induces anti-prolactin antibodies, ROS and cortisol but suppresses specific immune responses in rainbow trout
Transcriptional analysis of metabolic and virulence genes associated with biofilm formation in Piscirickettsia salmonis strains
Addressing viral and bacterial threats to salmon farming in Chile: historical contexts and perspectives for management and control
Analysis of single nucleotide polymorphisms (SNPs) associated with antibiotic resistance genes in Chilean Piscirickettsia salmonis strains
Early life stage bottlenecks of carnivorous molluscs under captivity: a challenge for their farming and contribution to seafood production
Multilocus sequence typing detects new Piscirickettsia salmonis hybrid genogroup in Chilean fish farms: Evidence for genetic diversity and population structure
BK potassium channel mRNA level changes in gills of Atlantic salmon after brackish water transfer
Comparative Pan-Genome Analysis of Piscirickettsia salmonis Reveals Genomic Divergences within Genogroups
Consecutive emamectin benzoate and deltamethrin treatments affect the expressions and activities of detoxification enzymes in the rainbow trout (Oncorhynchus mykiss)
Identification of genomic islands in Chilean Piscirickettsia salmonis strains and analysis of gene expression involved in virulence
New immunomodulatory role of neuropeptide Y (NPY) in Salmo salar leucocytes.
Search and analysis of genes involved in antibioticresistance in Chilean strains of Piscirickettsia salmonis
Immunostimulatory effect of salmon prolactin on expression of Toll-like receptors in Oncorhynchus mykiss infected with Piscirickettsia salmonis
Immunostimulatory effects of prolactin on TLR1 and TLR5M in SHK-1 cells infected with Piscirickettsia salmonis
Molecular cloning of Salmo salar Toll-like receptors (TLR1, TLR22, TLR5M and TLR5S) and expression analysis in SHK-1 cells during Piscirickettsia salmonis infection
Differential response of two somatolactin genes to zinc or estrogen in pituitary of Cyprinus carpio
Effectiveness of egg yolk immunoglobulin against the intracellular salmonid pathogen Piscirickettsia salmonis
Identification and genetic characterization of Piscirickettsia salmonis in native fish from southern Chile
Broth microdilution protocol for minimum inhibitory concentration (MIC) determinations of the intracellular salmonid pathogen Piscirickettsia salmonis to florfenicol and oxytetracycline
Draft Genome Sequence of Virulent Strain AUSTRAL-005 of Piscirickettsia salmonis, the Etiological Agent of Piscirickettsiosis
Identification of the clpB and bipA genes and an evaluation of their expression as related to intracellular survival for the bacterial pathogen Piscirickettsia salmonis
Immunomodulatory effect of prolactin on Atlantic salmon (Salmo salar) macrophage function
Two novel blood-free solid media for the culture of the salmonid pathogen Piscirickettsia salmonis
A new liquid medium for the pathogen Piscirickettsia salmonis
Broth medium for the successful culture of the fish pathogen Piscirickettsia salmonis
Prolactin-induced activation of phagocyte NADPH oxidase in the teleost fish gilthead seabream involves the phosphorylation of p47phox by protein kinase C
Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar
Structurally conserved C-RFa revealed prolactin releasing activity in vitro and gene expression changes in pituitary of seasonally acclimatized carp
Glandular kallikrein in the innate immune system of Atlantic salmon (Salmo salar)
Novel gene isolated from Caligus rogercresseyi: A promising target for vaccine development against sea lice
At least two expressed genes for transcription factors Pitx2 and Rpx are present in common carp and are upregulated during winter acclimatization
Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism
Copeptin, derived from isotocin precursor, is a probable prolactin releasing factor in carp
Cloning of the prepro C-RFa gene and brain localization of the active peptide in Salmo salar
Modular changes of cis-regulatory elements from two functional pit1 genes in the duplicated genome of Cyprinus carpio
Tissue expression of glandular kallikrein and its response to 17 beta-estradiol in the acclimatized carp
Andrographolide interferes with binding of nuclear factor-kappa B to DNA in HL-60-derived neutrophilic cells
Kinin B2 receptor-coupled signal transduction in human cultured keratinocytes
Seasonal modulation of growth hormone mRNA and protein levels in carp pituitary: evidence for two expressed genes
Use of reporter cell lines for detection of endocrine-disrupter activity
Whole-genome duplications in South American desert rodents (Octodontidae)
Glandular kallikreins in the teleost Cyprinus carpio: tissue distribution, possible involvement in prolactin processing, and effect of 17 beta-estradiol in vivo
Environmental reprogramming of the expression of protein kinase CK2 beta subunit in fish
In situ hybridization of somatolactin transcripts in the pituitary glands from acclimatized carp (Cyprinus carpio)
Environmental acclimatization of the carp modulates the transcription of ?-actin
Environmental acclimatization of the carp modulates the transcription of beta-actin
Seasonal adaptation modulates the expression of the protein kinase CK2 beta subunit gene in the carp
Genomic and proteomic aspects of p57 protein from Renibacterium salmoninarum: Characteristics in virulence patterns

Abstract (11)

Characterization and expressional analysis of Salmo salar heat shock proteins in response to Piscirickettsia salmonis infection under a cohabitation challenge
Identification and expression analysis of interleukin-8 from Atlantic salmon
Neuropeptide Y (NPY) revealed biological activity in leucocytes of Salmo salar
Cloning and characterization of cortisol receptor from Salmo salar and analyses of its role in fish leukocytes
Differential spatial expression of metal responsive transcription factor MTF-1 is related to functional organization of pituitary cells in Cyprinus carpio
Effect of prolactin on the immune system of S-salar challenged with Piscirickettsia salmonis
Identification of novel prolactin releasing peptide receptors of Cyprinus carpio and Salmo salar expressed in the pituitary gland
Kinin B1 but not B2 receptor agonists induce human neutrophil chemotaxis
Expression of CD40 and the mitogenic peptide hormone receptors vasopressin V1 and kinin B1 and B2 receptors in psoriatic epidermis
Molecular mechanisms involved in the modulation of nucleolar gene expression during the acclimatization of the carp fish
Growth hormone expression in carp pituitary during acclimatisation

Letter (1)

Resistance-nodulation-division efflux pump acrAB is modulated by florfenicol and contributes to drug resistance in the fish pathogen Piscirickettsia salmonis

Proyecto (15)

Desarrollo de un prototipo de vacuna proteica contra Renibacterium salmoninarum, causante del BKD (Bacterial Kidney Disease) en Salmo salar.
ESTUDIO INTEGRAL DE LAS BASES BIOLÓGICAS Y MOLECULARES DEL CICLO DE VIDA DE PISCIRICKETTSIA SALMONIS EN EL CONTEXTO DE UNA APROXIMACIÓN EPIDEMIOLÓGICA PARA DESARROLLAR ESTRATEGIAS QUE PERMITAN SU CONTROL
Estudio integral de las bases biológicas y moleculares del ciclo de vida de Piscirickettsia salmonis en el contexto de una aproximación epidemiológica para desarrollar estrategias que permitan su control
Programa para la Gestión Sanitaria en la Acuicultura (FIE)
RELATION BETWEEN IMMUNOSUPPRESSION EFFECT INDUCED BY CONFINEMENT STRESS AND SUSCEPTIBILITY TO BACTERIAL PATHOGENS IN SALMONID FISH=> STUDY OF CORTISOL MEDIATED MODULATION OF THE IMMUNE RESPONSE TO Piscirickettsia salmonis INFECTION IN STRESSED Salmo salar
Centro Interdisciplinario de Investigación en Acuicultura Sustentable (INCAR) Interdisciplinary Center for Aquaculture Research
Charaterization of the genes related to invasivity and intrecellular survival of P. salmonis=> An in vitro study of new virulence markers in chilean isolates of the causal agent of SRS
PROGRAMA DE VIGILANCIA EPIDEMIOLÓGICA Y CONTROL DE LA PISCIRICKETTSIOSIS (SRS) PARA LA COMPETITIVIDAD DE LA SALMONICULTURA CHILENA
Identification of the molecular mechanism envolved in Emamectin benzoate and pyretroids resistance in salmonid caligus infestations
Caracterización serológica, genómica y proteómica de los subtipos de Piscirickettsia salmonis presentes en la salmonicultura nacional=> Bases biotecnológicas para asegurar el desarrollo sustentable y competitivo de la industria salmonera.
Desarrollo y producción de una vacuna oral y de un fármaco inocuo en base a anticuerpos IgY para disminuir la mortalidad de salmones asociada a Piscirickettsia salmonis aumentando la competitividad y sustentabilidad de la industria salmonera
Interacción del sistema neuroendocrino e inmune en peces salmonídeos=> Estudio de la participación de NPY, C-Rfa y cortisol en la regulación de la actividad de macrófagos frente a infecciones bacterianas
evaluación del impacto ambiental sobre la expresión de factores hipotálamo-hipofisiarios de Cyprinus carpio
Prolactina y sus formas menores como inmunomoduladores de la respuesta de Salmo salar, frente a patógenos bacterianos
Regulación de la liberación de prolactina en pituitaria del pez C. carpio=> Efecto del copeptin asociado al precursor de arginina vasotocina
72
Jaime Figueroa

Profesor Titular

Bioquimica y Microbiologia

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

19
Alex Romero

Profesor Asociado

Facultad de Ciencias Veterinarias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

14
Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

12
Denise Haussmann

Profesora Titular

Departamento de Ciencias Básicas

Universidad Santo Tomás

Valdivia, Chile

9
Ruben Avendaño

Full Professor

UNIVERSIDAD ANDRÉS BELLO

Viña del Mar, Chile

7
Adolfo Isla

Asistente de investigacion Proyecto FONDAP-INCAR

Facultad de Ciencias

Universidad Austral de Chile

Valdivia, Chile

7
Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

4
Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

3
Claudio Alvarez

Investigador Titular

Corporación Centro de Estudios Avanzados en Zonas Aridas

Coquimbo, Chile

3
Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

3
Cristian Oliver

Investigador asociado a Proyecto

UNIVERSIDAD AUSTRAL DE CHILE

Chile

3
Hugo Silva

Asistente Científico

Cargill Innovation Centre

Cargill

Calbuco, Chile

3
Claudio Alvarez

Investigador Titular

Laboratorio FIGEMA

Centro de Estudios Avanzados en Zonas Aridas

Coquimbo, Chile

3
Roxana Gonzalez

Investigador Senior

Fundación Arturo López Pérez

Santiago, Chile

3
INGRID EHRENFELD

FULL PROFESSOR

ANATOMIA; HISTOLOGIA & PATOLOGIA

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

2
RENE MANRIQUEZ

Investigador Asociado

Universidad de Atacama

COPIAPO, Chile

2
Sergio Contreras

Jefe Departamento

Salud Hidrobiológica

Instituto de Fomento Pesquero

Puerto Montt, Chile

2
Augusto Manubens

Director

Tecnical Support

BIOSONDA S.A.

Santiago, Chile

2
Pamela Ruiz

Investigador

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

2
Patricio Sánchez

Asistente de Investigación

Departamento de Biología

Centro de Estudios Científicos

Valdivia, Chile

2
Luis Vargas

Full Professor

Universidad Austral de Chile

Valdivia, Chile

2
Juan Pontigo

Academico-Investigador

Medicina Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

2
Derie Fuentes

Director

Center For Systems Biotechnology

Universidad Andrés Bello

Santiago, Chile

1
Ana Farias

académico

Instituto de Acuicultura

UNIVERSIDAD AUSTRAL DE CHILE

Puerto Montt, Chile

1
Miguel del Campo

Investigador Adjunto Proyecto FONDECYT 151337

Fundación Ciencia y Tecnología para el Desarrollo

Santiago, Chile

1
Enrique Montiel

Profesor Asistente

Ciencias Básicas

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Rodrigo Montefusco

Profesor Auxiliar

Instituto de Aparato Locomotor y Rehabilitación

Universidad Austral de Chile

Valdivia, Chile

1
Leyla Cardenas

full professor

Instituto de ciencias ambientales y evolutivas

Universidad Austral de Chile

valdivia, Chile

1
Iker Uriarte

Académico Profesor Titular

Instituto de Acuicultura

UNIVERSIDAD AUSTRAL DE CHILE

Puerto Montt, Chile

1
Marcos Mancilla

Director Cientifico

Investigación y desarrollo

ADL Diagnostic Chile Ltda

Puerto Montt, Chile

1
Marcela Astorga

Full Professor (Profesor Titular)

UNIVERSIDAD AUSTRAL DE CHILE

Puerto Montt, Chile

1
Carolina Salazar

Profesor agregado

Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Jorge Navarro

Profesor Titular

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Kurt Paschke

profesor titular

Instituto de Acuicultura

UNIVERSIDAD AUSTRAL DE CHILE

Puerto Montt, Chile

1
Fabian Salazar

Postdoctoral Research Fellow

Biosciences

MRC Centre for Medical Mycology, University of Exeter

Exeter, Reino Unido

1
Jorge Toro

Full Professor

Instituto de Ciencias Marinas y Limnológicas

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Mauricio Hernandez

Subdirector Cientifico

Proteogenomica

MELISA Institute

San Pedro de la Paz, Chile

1
Nicolas Ojeda

Investigador Post-Doctoral

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Marcos Cortés

Tecnico

Instituto de Bioquímica y Microbiología

UACh/Veterquímica

Valdivia, Chile

1
VICTOR OLAVARRIA

PROFESOR ASOCIADO

BIOQUMICA Y MICROBIOLOGIA

Universidad Austral de Chile

valdivia, Chile

1
Franz Villarroel

Jefe Laboratorio - PI

Departamento de Investigación del Cáncer

Fundación Arturo López Pérez

Santiago, Chile

1
Marco Alvarez

Full Professor

Department of Biological Science

Universidad Andres Bello

Viña del Mar, Chile

1
Marcos Godoy

Director de Investigacion

Universidad San Sebastian

Puerto Montt, Chile

1
Carola Millan

Profesor

de Ciencias

UNIVERSIDAD ADOLFO IBAÑEZ FACULTAD DE ARTES LIBERALES

Viña del Mar, Chile

1
Sebastian Brauchi

Associate Professor

Physiology

Universidad Austral de Chile

Valdivia, Chile

1
MARIA HIDALGO

Associate professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Desmond MacLeod-Carey

Associate Professor

Facultad de Ingeniería

Universidad Autónoma de Chile

Santiago, Chile

1
Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

1
Monica Saldarriaga

Investigadora

Vicerrectoría de Vinculación con el medio e investigación

Universidad Bernardo O'Higgins

Santiago, Chile

1
Jannel Acosta

Profesor Asociado

Fisiopatología

Universidad de Concepción, Facultad de Ciencias Biológicas

Concepcion, Chile

1
Guillermo Valenzuela

Investigador Posdoctoral

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

1
María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

1
Marco Paredes

Profesor Asociado

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

1
Alvaro Muñoz

Profesor Titular

Universidad San Sebastián

Santiago, Chile

1
Victor Enríquez

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Julio Retamales

Profesor Investigador

Facultad de Medicina Veterinaria y Agronomía

Universidad d elas Américas

Viña del Mar, Chile

1
carlos molinet

ACADEMICO

INSTITUTO DE ACUICULTURA

UNIVERSIDAD AUSTRAL DE CHILE

Puerto Montt, Chile

1
Héctor Venegas

Profesor Titular asociado al Centro

Universidad Diego Portales

Santiago, Chile

1
Rafael Burgos

FULL PROFESSOR

PHARMACOLOGY AND MORPHOPHYSIOLOGY

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

1
GLADYS ASENCIO

Investigadora Asociada

CENTRO I-MAR, UNIV. DE LOS LAGOS

Pto Montt, Chile

1
PATRICIA AGUILA

Profesor Auxiliar categoria 3

Universidad Austral (UACH)

Puerto Montt, Chile

1
Ignacio Moreno

Full Professor

Facultad de Ciencias

Universidad Austral de Chile

Valdivia, Chile

1
René Vidal

Profesor Asistente

Universidad Mayor

Santiago, Chile

1
Paola Olmos

Jefe de Laboratorio

Vicerrectoría de Investigación y Doctorados

Universidad San Sebastián

Puerto Montt, Chile

1
Sharin Valdivia

Profesor Adjunto Adhonorem

Facultad de Ciencias

Universidad Austral de Chile

Valdivia, Chile

1
Jose Sarmiento

Assistant Professor

Physiology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Jorge Hernández

Investigador adjunto

Sede Puerto Montt

Universidad Austral de Chile

Puerto Montt, Chile