Man

Jose Mauricio Sarmiento Vargas

Assistant Professor

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Líneas de Investigación


Signal transduction; Inflammation; Structural Biology; Immunology; Cellular Biology; Immune system; adaptive Immune response; Chronobiology

Educación

  •  Molecular and Cell Biology, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2005
  •  Bioquimico, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1997

Experiencia Académica

  •   Assistan Professor Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Medicine

    Valdivia, Chile

    2005 - A la fecha

Experiencia Profesional

  •   Technical Academic Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    1999 - 2005

Formación de Capital Humano


2014
"Rol de los Mastocitos en la Inflamación Crónica Alérgica de las Vías Aéreas"
Amber R. Philp
Para optar al título profesional de Bioquímico (en desarrollo)

“Caracterización de mastocitos STAT6 knock out”
Rodrigo Gonzalez Kindley.
Para optar a Licenciatura y Grado de Tecnología Médica.
Universidad Austral de Chile.

“Subclonamiento del promotor de músculo liso SMP8 para la generación del
animal SMP8-TMEM16A+/+/TMEM16A-/-”
José Álvarez Iturra.
Para optar a Licenciatura y Grado de Tecnología Médica.
Universidad Austral de Chile.

“Rol de KCNN4 en neutrófilos”
Daniel Vera Díaz.
Para optar a Licenciatura y Grado de Tecnología Médica.
Universidad Austral de Chile.

"Rol del óxido nítrico sobre la permeabilidad microvascular mediada por Interleuquina-8”
Anita Hilda Luisa Guequen Cardenas
Para optar al grado de Bioquímico y Título Profesional de Bioquímico
Universidad Austral de Chile.

2013
“Generación del animal SMP8-TMEM16A+/+/TMEM16A-/- y estudio de la
distribución del canal TMEM16A en tejidos de ratón.”
José Arellano Ruiz.
Para optar a Licenciatura y Grado de Tecnología Médica.
Universidad Austral de Chile.

“Regulación de mastocitos en la fibrosis quística por el canal KCNN4.”
Texia Riquelme Mora.
Para optar a Licenciatura y Grado de Tecnología Médica.
Universidad Austral de Chile.


Premios y Distinciones

  •   Short Term Grant MECE Competitive Fund AUSMECESUP Project 006

    UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON

    Chile, 2002

    Short Term Grant MECE Competitive Fund AUSMECESUP Project 006 Institution: UNIVERSITY OF TEXAS MEDICAL BRANCH Country of Studies: ESTADOS UNIDOS DE AMERICA Year awarded: 2002

  •   Becas Chile

    UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON

    Estados Unidos, 2008

    Postdoctoral Position at the Department of Neuroscience and Cell Biology Institution: UNIVERSITY OF TEXAS MEDICAL BRANCH Country of Studies: ESTADOS UNIDOS DE AMERICA Year awarded: 2008


 

Article (33)

Interleukin-8 Secreted by Glioblastoma Cells Induces Microvascular Hyperpermeability Through NO Signaling Involving S-Nitrosylation of VE-Cadherin and p120 in Endothelial Cells
Long-Term Effects of Altered Photoperiod During Pregnancy on Liver Gene Expression of the Progeny
Tamoxifen induces apoptotic neutrophil efferocytosis in horses
Tamoxifen inhibits chemokinesis in equine neutrophils
In Vitro effects of tamoxifen on equine neutrophils.
Modulatory role of regulatory T cells in a murine model of severe equine asthma.
S-nitrosylation of VASP at Cysteine 64 Mediates Inflammation Stimulated Increase in Microvascular Permeability.
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease
S-nitrosylation regulates VE-cadherin phosphorylation and internalization in microvascular permeability.
S-nitrosylation regulates VE-cadherin phosphorylation and internalization in microvascular permeability.
Tamoxifen as a new therapeutic tool for neutrophilic lung inflammation
The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils
Expression and bioregulation of the kallikrein-related peptidases family in the human neutrophil
Kinin B-1 receptor regulates interactions between neutrophils and endothelial cells by modulating the levels of Mac-1, LFA-1 and intercellular adhesion molecule-1
Bioregulation of Kallikrein-related Peptidases 6, 10 and 11 by the Kinin B-1 Receptor in Breast Cancer Cells
Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the Kinin b1 receptor in breast cancer cells
Kinin B1 receptor regulates interactions between neutrophils and endothelial cells by modulating the levels of Mac-1, LFA-1 and intercellular adhesion molecule-1.
Participation of T regulatory cells in equine recurrent airway obstruction
SVCT2 transporter expression is post-natally induced in cortical neurons and its function is regulated by its short isoform
Apoptotic effects of tamoxifen on leukocytes from horse peripheral blood and bronchoalveolar lavage fluid
Chemokine CXCL1 dimer is a potent agonist for the CXCR2 receptor
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
Diverging Mechanisms of Activation of Chemokine Receptors Revealed by Novel Chemokine Agonists
The Splice Variant of the V2 Vasopressin Receptor Adopts Alternative Topologies
Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors
Adenovirus mediated expression "in vivo" of the chemokine receptor CXCR1
Postnatal expression of V-2 vasopressin receptor splice variants in the rat cerebellum
Activation of kinin B(1) receptor triggers differentiation of cultured human keratinocytes
Vasopressin up-regulates the expression of growth-related immediate-early genes via two distinct EGF receptor transactivation pathways
Differential distribution of the vasopressin V-2 receptor along the rat nephron during renal ontogeny and maturation
Novel down-regulatory mechanism of the surface expression of the vasopressin V-2 receptor by an alternative splice receptor variant
Polarized expression of the GFP-tagged rat V-1a vasopressin receptor
Environmental acclimatization of the carp modulates the transcription of beta-actin

Abstract (2)

Kinins and their receptors, a new autocrine-paracrine signaling pathway that contributes to breast cancer malignancy
Kinin-induced filaggrin expression is enhanced after blocking EGF receptor transactivation in human keratinocytes

Proyecto (9)

EFFECTS OF TAMOXIFEN ON PRO-RESOLUTIVE MECHANISMS OF INFLAMMATION IN HORSES WITH RECURRENT AIRWAY OBSTRUCTION
Gestational chronodisruption=> a novel determinant for allergic asthma in the adulthood?
SIGNALING MECHANISMS REGULATED BY ENOS-S-NITROSATION AT THE ONSET OF THE INFLAMMATORY PROCESS.
USE OF TAMOXIFEN AS A NEW THERAPEUTIC TOOL FOR HORSES WITH RECURRENT AIRWAY OBSTRUCTION
Mecanismos fisiopatológicos de enfermedades crónicas del adulto impuestas por la alteración circadiana prenatal=> valor terapéutico del tratamiento con melatonina a la madre expuesta a turnos nocturnos durante la gestación
ROL DE LA OLIGOMERIZACION EN LA MADURACION DE LOS RECEPTORES V2 DE VASOPRESINA.
FORMACION DE OLIGOMEROS DE RECEPTORES DE VASOPRESINA Y SU PAPEL EN LA MODULACION DE LOS MECANISMOS EN TRANSDUCCION, ESPECIFICAMENTE, AQUELLOS RELACIONADOS CON PROLIFERACION CELULAR
Formación de multímeros en la isoforma V2 de receptores de Vasopresina
ESTRUCTURA Y FUNCION DE RECEPTORES, CARACTERIZACION DE SUS MECANISMOS DE TRANSDUCCION Y SU ROL EN PROLIFERACION Y DIFERENCIACION CELULAR
31
Jose Sarmiento

Assistant Professor

Physiology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

8
INGRID EHRENFELD

ASSOCIATE PROFESSOR

ANATOMIA; HISTOLOGIA & PATOLOGIA

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

6
Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

5
María García

Profesor Titular

Biología Celular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

4
Claudio Henríquez

Auxiliar Professor

Farmacology and Morphophysiology

Universidad Austral de Chile

Valdivia, Chile

3
BENJAMIN UBERTI

Assistant Professor

Facultad de Ciencias Veterinarias

Universidad Austral de Chile

Valdivia, Chile

3
CAROLINA AÑAZCO

Associate Professor

Preclinical Sciences

Universidad Católica del Maule

TALCA, Chile

2
MARIANNE BRENET

Investigador

SymbiOx Inc.

Macul, Chile

1
Priscilla Brebi

Profesor Asociado

Departamento de Anatomía Patológica.

Universidad de La Frontera

Temuco, Chile

1
Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

1
Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

1
Juan Tapia

Profesor

UNIVERSIDAD DE TALCA

Talca, Chile

1
Fernando Martinez

Assistant Professor

Cell Biology

Universidad de Concepción

Concepción, Chile

1
Diego Halabi

Profesor Auxiliar

Escuela de Odontología

Universidad Austral de Chile

Valdivia, Chile

1
Fabiola Sánchez

Associate Profesor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
César Trigo

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

1
Natalia Mendez

Profesor Auxiliar

UNIVERSIDAD AUSTRAL DE CHILE

valdivia, Chile

1
Hans Richter

Profesor Titular

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

1
MARIA HIDALGO

Associate professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Katterine Salazar

Associate Professor

Cell Biology

University of Concepcion

Concepción, Chile

1
Claudia Torres

Full Professor

Instituto de Anatomía, Histología y Patología

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Ángelo Torres

Postdoctorado/Profesor Adjunto

Microbiología y Bioquímica

Universidad Austral de Chile

Valdivia, Chile

1
Lida Fuentes

Researcher

Centro Regional de Estudios en Alimentos Saludables

Valparaiso, Chile

1
Gabriel Moran

Associate Professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Anita Guequen

Asistente de investigación

Biología

Centro Estudios Científicos (CECs)

Valdivia, Chile

1
Hugo Folch

Professor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Jaime Figueroa

Profesor Titular

Bioquimica y Microbiologia

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile