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Rina Jemile Ortiz Diban

Académica

Universidad Vina del Mar

Viña del Mar, Chile

Bionanotecnología en el diagnóstico de cáncer Ingeniería de tejidos Biología celular del cáncer

Licenciatura en Biología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Doctorado en Farmacología, UNIVERSIDAD DE CHILE. Chile, 2015
Bióloga con especialidad en bioprocesos, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008

Profesora investigadora Full Time

UNIVERSIDAD TECNICA FEDERICO SANTA MARIA

Valparaíso, Chile

2019 - 2020
Instructor adjunto Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biológicas

Santiago, Chile

2008 - Sin Información
Académica Full Time

Universidad Viña del Mar

Viña del Mar, Chile

2024 - A la fecha
Docente Part Time

Universidad Bernardo O'Higgins

Santiago, Chile

2015 - 2016

Instructor adjunto Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2008 - 2008
Professional trainee-Gerencia Medio Ambiente Full Time

Compañía Minera Doña Inés de Collahuasi

Iquique, Chile

2008 - 2008
Profesora de Fisiología Part Time

Universidad Bernardo O´Higgins

Santiago, Chile

2015 - 2016
Docente Jefa catedra Farmacología Part Time

Universidad Iberoamericana de Ciencias y Tecnología

Santiago, Chile

2012 - 2012
Ayudante del curso Biología de la Célula Part Time

Pontificia Universida Católica de Chile

Santiago, Chile

2007 - 2008
Ayudante del curso Reproducción Animal Part Time

Pontificia Universida Católica de Chile

Santiago, Chile

2007 - 2008
Ayudante del curso Biología Animal Part Time

Pontificia Universida Católica de Chile

Santiago, Chile

2007 - 2007
Ayudante del curso Bioquímica y Fisiología Vegetal Part Time

Pontificia Universida Católica de Chile

Santiago, Chile

2006 - 2006
Ayudante del curso Reproducción Sexual en Mamíferos-programa PENTA UC Part Time

Pontificia Universida Católica de Chile

Santiago, Chile

2004 - 2004
Profesora investigadora Full Time

Universidad Técnica Federico Santa María

Valparaiso, Chile

2019 - 2020
Post doctorado Full Time

Universidad Técnica Federico Santa María

Valparaiso, Chile

2017 - 2019
Evaluador Comité Biotecnología Part Time

ANID

Santiago, Chile

2019 - A la fecha
Asistente de investigación-proyecto FONDECYT Part Time

Universidad Técnica Federico Santa María

Valparaiso, Chile

2016 - 2018
Asistente de investigación Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2008 - 2008
Académica Full Time

Universidad Viña del Mar

Viña del Mar, Chile

2024 - A la fecha
Administradora Full Time

Comercializadora Farmaceutica Los Copihues

Viña del Mar, Chile

2021 - 2023

Best image prize

Advanced Center for Chronic Deseases (ACCDiS)

Chile, 2016

Premio a la mejor imágen en cáncer del ACCDiS Cancer Spring Symposium, 2016


Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response Diaz, Maria I.; Diaz, Paula; Bennett, Jimena Castillo; Urra, Hery; Ortiz, Rina; Orellana, Pamela Contreras; Hetz, Claudio; Quest, Andrew F. G. Article ISI CELL DEATH & DISEASE (2020)
Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells Ortiz, Rina; Diaz, Jorge; Diaz-Valdivia, Natalia; Martinez, Samuel; Simon, Layla; Contreras, Pamela; Lobos-Gonzalez, Lorena; Guerrero, Simon; Leyton, Lisette; Quest, Andrew F. G. Article ISI BIOCHEMICAL PHARMACOLOGY (2020)
Design of a biodegradable UV-irradiated gelatin-chitosan/nanocomposed membrane with osteogenic ability for application in bone regeneration Acevedo C.A.; OlguÃn Y.; BriceÃ±o M.; Forero J.C.; Osses N.; DÃaz-CalderÃ³n P.; Jaques A.; Ortiz R. Article ISI SCOPUS MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)
The 12-HHT/BLT2/NO Axis Is Associated to the Wound Healing and Skin Condition in Different Glycaemic States Leguina-Ruzzi, Alberto; Ortiz, Rina; Velarde, Victoria Article Medical Sciences (2019)
A novel biomaterial based on salmon-gelatin and its in vivo evaluation as sterile wound-dressing Enrione, J; Pino, K; Pepczynska, M; Brown, DI; Ortiz, R; Sanchez, E; Acevedo, CA Article ISI SCOPUS MATERIALS LETTERS (2018)
The streptozotocin-high fat diet induced diabetic mouse model exhibits severe skin damage and alterations in local lipid mediators Leguina-Ruzzi A.; Ortiz R.; Velarde V. Article ISI SCOPUS Biomedical Journal (2018)
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis Ortiz, Rina; Díaz, Jorge; Díaz, Natalia; Lobos-Gonzalez, Lorena; Cárdenas, Areli; Contreras, Pamela; Díaz, María Inés; Otte, Ellen; Cooper-White, Justin; Torres, Vicente; Leyton, Lisette; Quest, Andrew Frederick. Article Oncotarget (2016)
Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells Wehinger, S; Ortiz, R; Diaz M.I.; Aguirre, A; Valenzuela, M; Llanos, P; Mc Master C.; Leyton L; Quest, A. F. G. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion Diaz J; Mendoza P; Ortiz, R; Diaz N; Leyton L; Stupack, D.; Quest AF; Torres VA Article JOURNAL OF CELL SCIENCE (2014)
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells Mendoza P; Ortiz, R; Diaz J; Quest, AFG; Leyton L; Stupack, D.; Torres VA Article JOURNAL OF CELL SCIENCE (2013)
Caveolin-1-Enhanced Motility and Focal Adhesion Turnover Require Tyrosine-14 but Not Accumulation to the Rear in Metastatic Cancer Cells Urra, H; Torres, V.A.; Ortiz R.J.; Lobos, L; Díaz M.I.; Díaz N; Hartel, S; Leyton, L; Quest, A.F.G. Article ISI SCOPUS PLOS ONE (2012)
A molecular evaluation of germ cell death induced by etoposide in pubertal rat testes Ortiz, Rina; Lizama, Carlos; Codelia, Verónica; Moreno, Ricardo. Article MOLECULAR HUMAN REPRODUCTION (2009)


Caveolae-independent Caveolin-1 translocation to focal adhesions upon melanoma adhesion and spreading. Ortiz, R; Cardenas, A; Leyton, L; Quest, AF Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2016)


MICRODEVICE DESIGN FOR EARLY CANCER DIAGNOSIS BASED ON LAB-ON-A-CHIP APPROACH Ortiz, Rina Proyecto (2020)
A FOOD ENGINEERING APPROACH TO CULTURE IN-VITRO MEAT USING MICROPATTERNED FILMS Acevedo, Cristian; Ortiz, Rina; Sánchez, Elizabeth Proyecto (2019)
BIOINTERFAZ: EN LA BÚSQUEDA DE LA CONEXIÓN HOMBRE-MÁQUINA Ortiz, Rina Proyecto (2019)
DESIGN OF AN INTEGRATED BIODEVICE WITH OSTEOGENIC ABILITY FOR APPLICATION IN BONE REGENERATION. Ortiz, Rina Proyecto (2017)
ELUCIDATION OF THE MECHANISMS UNDERLYING RAB5 MEDIATED FOCAL ADHESION DISASSEMBLY, CANCER CELL MIGRATION AND INVASION FONDECYT (1140907) Proyecto 2014-2018 Tesista
CAVEOLIN-1-DEPENDENT MIGRATION AND METASTASIS OF CANCER CELLS REQUIRES TYR14 PHOSPHORYLATION, SEQUESTRATION OF P85A AND ACTIVATION OF THE RAB5-RAC1 PATHWAY, WHICH ARE INHIBITED BY EXPRESSION OF E-CADHERIN FONDECYT (1130250) Proyecto 2013-2017 Tesista
PRO-INFLAMMATORY STIMULI INCREASE ALPHAVBETA3 INTEGRIN EXPRESSION IN ASTROCYTES, WHICH UPON ENGAGEMENT OF NEURONAL THY-1 TRIGGERS BIDIRECTIONAL-SIGNALING EVENTS REQUIRED FOR ASTROCYTE MIGRATION AND AXONAL RETRACTION. FONDECYT (1110149) Proyecto 2011-2015 Tesista
ROLE OF RAB5 IN CELL MIGRATION AND METASTASIS FONDECYT (11100287) Proyecto 2010-2013 Tesista
SUPPRESSION OF TUMOR GROWTH BY CAVEOLIN-1 INVOLVES INHIBITION OF THE UNFOLDED PROTEIN RESPONSE FONDECYT (1090071) Proyecto 2010-2015 Tesista
PAPEL DE LA TACE/ADAM17 EN LA APOPTOSIS DEPENDIENTE DE P53 DURANTE LA ESPERMATOGENESIS DE MAMIFEROS. FONDECYT (1070360) Proyecto 2007-2011 Tesista
REGULACION DEL NUMERO DE ESPERMATOGONIAS POR MUERTE CELULAR PROGRAMADA=> POSIBLE PAPEL DE C-KIT Y FAS EN LA REGULACION DE LA ACTIVACION DE LAS CASPASAS FONDECYT (1040800) Proyecto 2004-2007 Tesista


Current Evidence for the Use of Smoflipid® Emulsion in Critical Care Patients for Parenteral Nutrition Leguina-Ruzzi A.A.; Ortiz R. Review WOS-ESCI SCOPUS (2018)