Man

RICARDO CASTRO LOPEZ

Jefe de unidad

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Outcomes clínicos del paciente crítico Shock séptico

Educación

  •  Public Health, UNIVERSITY OF PITTSBURGH. Estados Unidos, 2011
  •  Medico Cirujano, UNIVERSIDAD DE CONCEPCION. Chile, 1995
  •  Medicine, ERASMUS UNIVERSITY ROTTERDAM. Holanda, 2025

Experiencia Académica

  •   Profesor Asistente Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2006 - A la fecha

Experiencia Profesional

  •   Profesor Asociado Full Time

    Pontificia Universidad Catolica de Chile

    Chile

    2006 - A la fecha


 

Article (49)

Critical closing pressure in the circulation: Understanding the vascular waterfall phenomenon
Endothelial dysfunction in critically ill patients with sepsis and COVID-19 using the albumin transudation rate: A pilot study
What every intensivist should know about the biphasic kinetics of lactate in septic shock
Bayesian analysis of a randomized controlled trial: mathematical and clinical aspects
Capillary refill time response to a fluid challenge or a vasopressor test: an observational, proof-of-concept study
Coexistence of a fluid responsive state and venous congestion signals in critically ill patients: a multicenter observational proof-of-concept study
Differential Cardiac Responses after Passive Leg Raising
Dynamic changes of hepatic vein Doppler velocities predict preload responsiveness in mechanically ventilated critically ill patients
Fluid Responsiveness Is Associated with Successful Weaning after Liver Transplant Surgery
Preload responsiveness-guided fluid removal in mechanically ventilated patients with fluid overload: A comprehensive clinical-physiological study
The impact of norepinephrine dose reporting heterogeneity on mortality prediction in septic shock patients
Hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial study protocol
Ressuscitação direcionada ao tempo de enchimento capilar baseada em fenótipo hemodinâmico no choque séptico precoce: protocolo de estudo do ensaio clínico randomizado ANDROMEDA-SHOCK-2
Secondary respiratory early and late infections in mechanically ventilated patients with COVID-19
The emerging concept of fluid tolerance: A position paper
Blood volume and albumin transudation in critically ill COVID-19 patients
Early versus deferred anti-SARS-CoV-2 convalescent plasma in patients admitted for COVID-19: A randomized phase II clinical trial
Fallacy of the last bed dilemma
Intubation timing as determinant of outcome in patients with acute respiratory distress syndrome by SARS-CoV-2 infection
A lactate-targeted resuscitation strategy may be associated with higher mortality in patients with septic shock and normal capillary refill time: a post hoc analysis of the ANDROMEDA-SHOCK study
Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial
Ethical guidelines for medical decision-making during COVID-19 pandemic in Chile
Hypoxia-related parameters during septic shock resuscitation: Pathophysiological determinants and potential clinical implications
Optimal target in septic shock resuscitation
The seven Ts of capillary refill time: more than a clinical sign for septic shock patients
Early rise in central venous pressure during a spontaneous breathing trial: A promising test to identify patients at high risk of weaning failure?
The impact of a better coordination between emergency and intensive care units in the care of critically ill patients
What is the role of corticosteroids in the management of sepsis?
What is the role of recombinant activated protein C in the management of sepsis?
Posttraumatic stress disorder symptoms in close relatives of intensive care unit patients: Prevalence data resemble that of earthquake survivors in Chile
Management of the potential organ donor
When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring
Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study
Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients
Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study
Light and the outcome of the critically ill: an observational cohort study
Natriuretic peptide type-B can be a marker of reperfusion in patients with pulmonary thromboembolism subjected to invasive treatment
Persistent sepsis-induced hypotension without hyperlactatemia: A distinct clinical and physiological profile within the spectrum of septic shock
Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study
Persistent sepsis-induced hypotension without hyperlactatemia: Is it really septic shock?
The effect of light on critical illness
Diagnostic yield of CT pulmonary angiography and venography for thromboembolic disease
Diagnostic yield of CT pulmonary angiography and venography for thromboembolic disease Evaluación prospectiva de la venografía mediante angio TC en el diagnóstico de enfermedad tromboembólica
Evaluación prospectiva de la venografía mediante angioTC en el diagnóstico de enfermedad tromboembólica
Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study
An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock
Intra-abdominal hypertension: Incidence and association with organ dysfunction during early septic shock
Pro- and anti-inflammatory balance of septic patients is associated with severity and outcome
High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock

Abstract (7)

Is Gamma (P.1) Variant Associated with a Higher Severity in ICU Patients with SARS-CoV-2 Infection
RELATIONSHIP OF SYSTEMIC, HEPATOSPLANCHNIC AND MICROCIRCULATORY PERFUSION PARAMETERS WITH SIX-HOUR LACTATE CLEARANCE IN HYPERDYNAMIC SEPTIC SHOCK PATIENTS: AN ACUTE CLINICAL-PHYSIOLOGICAL PILOT STUDY
EFFECTS OF DOBUTAMINE ON MICROCIRCULATION, REGIONAL AND PERIPHERAL PERFUSION IN SEPTIC SHOCK PATIENTS: A RANDOMIZED DOUBLE BLIND CROSSOVER TRIAL. PRELIMINARY REPORT
THE RELATIONSHIP BETWEEN MICROCIRCULATORY FLOW ABNORMALITIES AND SYSTEMIC HEMODYNAMIC VARIABLES IN SEPTIC SHOCK PATIENTS. A MULTICENTRE CROSS-SECTIONAL STUDY
EARLY NORMALIZATION OF CENTRAL VENOUS O-2 SATURATION AFTER EMERGENCY INTUBATION IN SEPTIC PATIENTS DOES NOT ASSURE AN IMPROVEMENT IN GLOBAL DYSOXIA
SEPTIC SHOCK: HETEROGENEOUS DISEASE OR INAPPROPRIATE DEFINITIONS
High frequency of cholestatic variant in Chilean patients with autoimmune hepatitis

EditorialMaterial (1)

I wished she had meningoencephalitis

Letter (10)

Venous waterfalls mainly buffer backward pressure transmission
Capillary refill time as an additional triage criterion to decide ICU admission of deteriorating obstetric patients
Comment on: 'presentation of a novel method to estimate analog mean systemic filling pressure based on cardiac power' -on correlation, coupling, and physiological meaning
Reply to: Co-existence of congestion and preload-dependence identified by pulse pressure respiratory variations: right ventricular afterload might be the key
Comment on the article Physiological effects and safety of bed verticalization in patients with acute respiratory distress syndrome, from Bouchant et al.
Author's response: The emerging concept of fluid tolerance: A position paper
Reply to: What is meant by “fluid tolerance ?”
A combination of Bohr and Haldane effects provide a physiologic explanation for the increase in arterial oxygen saturation when a face mask is added to a high-flow nasal cannula in severely hypoxemic COVID-19 patients
Immediate cardiac arrest resuscitation skills are acquired in 8th grade students during normal class hours with a low-cost, short-term, self-instruction video
Reply to letter: Teaching and outcomes standards in community-based CPR training programs: Walking one step at a time

Review (4)

Can we reliably use pulse pressure as a surrogate for stroke volume? Physiological background and potential clinical implications for shock resuscitation
Venous congestion from a vascular waterfall perspective: reframing congestion as a dynamic Starling resistor phenomenon
Current practice and evolving concepts in septic shock resuscitation
The holistic view on perfusion monitoring in septic shock
1
MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Jaime Pereira

Jefe

Hematología-Oncología

ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Marcela Ferres

Head of Department

Pediatric Infectious Diseases and Immunology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Patricio Downey

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE DEPARTAMENTO DE NEFROLOGIA

SANTIAGO, Chile

3
Rodrigo Cornejo

Jefe de Servicio

Medicina

UNIVERSAIDAD DE CHILE-HOSPITAL CLINICO UNIVERSIDAD DE CHILE

Santiago, Chile

2
maría carrasco

PONTIFICIA UNIVERSIDAD CATÓLICA FACULTAD DE FILOSOFÍA

Santiago, Chile

1
MARIO CALVO

Profesor Asociado

Instituto de Medicina

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

1
Luis Cortínez

Profesor Titular

DIVISIÓN DE ANESTESIOLOGÍA

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

2
Samuel Cordova

ESCUELA DE MEDICINA, PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Franz Villarroel

Jefe Laboratorio - PI

Departamento de Investigación del Cáncer

Fundación Arturo López Pérez

Santiago, Chile

1
Ricardo Soto

PROFESOR ASOCIADO

FACULTAD DE MEDICINA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

16
Alejandro Bruhn

Profesor Titular. Director de Investigación y Postgrado, Facultad de Medicina

Departamento de Medicina Intensiva

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
María Balcells

Associate Professor

Department of Infectious Diseases of the Adult

Pontificia Universidad Catolica de Chile

Santiago, Chile

3
Orlando Diaz

Profesor Asociado

Enfermedades Respiratorias

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Monique Le Corre

Assistant Professor

Faculty of medicine, Pediatric division

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Manuel Espinoza

Profesor Asociado

Salud Pública

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

8
Max Andresen

profesor asociado categoria ordinaria

medicina Intensiva

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

7
Jaime Retamal

Profesor Asociado

Medicina Intensiva

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

5
Guillermo Bugedo

Staff Medicina Intensiva

Medicina Intensiva

Pontifica Universidad Catolica de Chile

Santiago, Chile

4
luis rojas

Profesor asistente

Medicina Interna

Pontificia Universidad católica de Chile. Facultad de Medicina, Escuela de Medicina

Santiago, Chile

3
Arnoldo Riquelme

Director UDA Ciencias de la Salud (Carreras de Nutrición y dietética, Fonoaudiología y Kinesiología)

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

8
María Vera

Académico

Medicina Intensiva

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Ronald Pairumani

Médico intensivista

UCI

Hospital Barros Luco

Santiago, Chile

4
Leyla Alegria

Profesor Asistente

Medicina Intensiva

Pontificia Universidad Católica de Chile

Santiago, Chile

72
RICARDO CASTRO

Jefe de unidad

Pontificia Universidad Católica de Chile

Santiago, Chile

14
Alejandro Bruhn

Jefe Unidad de Paciente Critico

Hospital Clinico de la Universidad Catolica

Santiago, Chile

1
Andres Aquevedo

Instructor Adjunto

Medicina Intensiva

Pontificia Universidad Católica de Chile

Santiago, Chile

20
Eduardo Kattan

Profesor Asistente

Medicina Intensiva

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile

1
Catalina Pardo

Profesor Asistente

Dpto. de Salud del Niño y Adolescente

Pontificia Universidad Católica de Chile

Region Metropolitana, Chile

1
Sebastián Dubo

Profesor Asociado

Kinesiología

Universidad de Concepción

Concpeción, Chile

2
Christian Labra

kinesiólogo

kinesiología

Hospital red de salud UC

santiago, Chile

2
leticia clede .

staff

anestesia

hospital La Florida

santiago, Chile

2
Alberto Sarfatis

Profesor Clínico Asistente

Medicina Interna

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Carolina Ruiz

Medico Jefe UPC

Unidad de Paciente Crítico

Complejo Asistencial Sotero del Rio

Santiago, Chile

1
Elizabeth Rivas

Lab manager

Trasplante y Perfusión Ex vivo

Instituto de Ingenieria Biologica y Médica

Santiago, Chile

2
Vanessa Oviedo

ENFERMERA DE INVESTIGACIÓN

DEPARTAMENTO DE MEDICINA INTENSIVA

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
María Elena Ceballos

Profesor Asistente

Enfermedades Infecciosas del Adulto

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Patricio Ross

Instructor Adjunto

Enfermedades Infecciosas del Adulto

Pontificia Universidad Católica de Chile

Santiago, Chile

1
María Domínguez

Profesora asistente adjunta

Departamento de Salud Pública

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Jenniffer Angulo

Profesos Asistente

Enfermedades Infecciosas e Inmunología Pediátricas

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Carolina Selman

Subdirectora

Unidades de Diagnóstico

Fundación Arturo Lopez Perez

Santiago, Chile

1
Macarena Amthauer

Enfermera de Investigación

Medicina Intensiva

Pontificia Universidad Católica de Chile

Santiago, Chile

5
cesar pedreros

médico intensivista

centro paciente critico

clinica las condes

santiago, Chile

2
César Santis

Médico

Unidad Cuidados Intensivos

Hospital Barros Luco

Santiago, Chile