Man

Sylvain Marcellini Liotaud

Associate Professor

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Líneas de Investigación


Control of gene expression during organogenesis. Transcriptomic analyses of gene expression during cell differentiation. Epigenomic analyses of chromatin status during cell differentiation. Dioxin-dependent AhR activation

Educación

  •  Genetics and Cell Biology, UNIVERSITE DE LA MEDITERRANEE : AIX-MARSEILLE II. Francia, 2002

Experiencia Académica

  •   Post-Doc Full Time

    University of Cambridge

    Cambridge, Reino Unido

    2003 - 2005

  •   Post-Doc Full Time

    Universidad de Concepcion

    Facultad de Ciencias Biologicas

    Concepcion, Chile

    2006 - 2007

  •   Associate Professor Full Time

    Universidad de Concepcion

    Facultad de Ciencias Biologicas

    Concepcion, Chile

    2008 - A la fecha

Experiencia Profesional

  •   Delegado de Relaciones Institucionales e Internacionales Full Time

    Facultad de Ciencias Biologicas, Universidad de Concepcion

    Chile

    2010 - A la fecha

  •   Evaluador Becas CHILE Part Time

    CONICYT

    Chile

    2010 - A la fecha

  •   Coordinador Comité de Biología Celular y Molecular (Formación de Capital Humano Avanzado) Part Time

    CONICYT

    Chile

    2011 - 2014

  •   Par Evaluador Part Time

    CNA

    Chile

    2014 - A la fecha

  •   Miembro del Grupo de Estudio Biologia 2 Part Time

    CONICYT - FONDECYT

    Chile

    2015 - 2017

  •   Tesorero Part Time

    Latin American Society for Developmental Biology (LASDB)

    Chile

    2017 - A la fecha

Formación de Capital Humano


PhD THESES
Adrian ROMERO (PhD thesis, TUTOR) “Regulatory architecture of the SCPP gene cluster”, Ongoing
David MUÑOZ (PhD thesis, TUTOR) “Evolutionary origin of the osteogenic role of the Osterix transcription factor”, Ongoing
Fret CERVANTES (PhD thesis, TUTOR) “Rewiring of the Sox9-dependent osteogenic regulatory network”, Ongoing
Gabriela Torro (PhD thesis, CO-TUTOR) “Role of Ric8 during neural crest formation”. Co-directed with the Dr. Marcela Torrejon, University of Concepcion. Finished in 2016.
Patricia HANNA (PhD thesis, TUTOR) “Transcriptional control of osteoblast and osteocyte-specific genes in Xenopus tropicalis”, Finished in 2014.
Ariana BERTIN (PhD thesis, CO-TUTOR) “Signaling pathways driving the propagation of the mineralization front in intramembraneous bone”, Co-directed with the Dr. Juan Pablo Henriquez, University of Concepcion. Finished in 2014.

MASTER THESES
Pedro CONTRERAS (Master thesis, TUTOR) “Role of repeated sequences embedded within osteoblastic transcriptional enhancers”, Finished in 2017
Hector CASTILLO (Master thesis, TUTOR), “An improved fluorescent in vivo bioassay to detect contamination of Chilean drinkable waters resources”, Finished in 2017
David MUNOZ (Master thesis, TUTOR) “Expression and regulation of the collagen genes in Xenopus tropicalis developing bones”, Finished in 2015
Gastón OTAROLA (Master thesis, TUTOR) “A novel biosensor system to detect contamination of Chilean drinkable waters resources”, Finished in 2014

UNDERGRADUATE THESES
Rodrigo MENDEZ (Undergraduate thesis, TUTOR) “Tissue-specific response to dioxins”, Ongoing
Francisca BERMEDO (Undergraduate thesis, CO-TUTOR), “Neuromuscular junction formation in Xenopus”. Finished in 2016
Pedro CONTRERAS (Undergraduate thesis, TUTOR) “Transcriptional regulation in skeletal cells”, Finished in 2016
David NAVARRO (Undergraduate thesis, TUTOR) “Evolution of the expression and function of the btg family members”, Finished in 2014
Alan FRITZ (Undergraduate thesis, TUTOR) “Morphological description of osteocytogenesis in the developing Xenopus tropicalis calvaria”, Finished in 2014
Gastón OTAROLA (Undergraduate thesis, TUTOR) “Generation of inducible transgenesis vector to study biological processes in Xenopus tropicalis”, Finished in 2012
Daniel ALDEA (Undergraduate thesis, TUTOR) “Evolution of the network forming collagen family”, Finished in 2012
Federico JARA (Undergraduate thesis, TUTOR) “Anatomical comparison of skeletal development between Xenopus tropicalis and Chilean endemic frog species”, Finished in 2011
Javier ESPINOZA (Undergraduate thesis, TUTOR) “An histological and molecular analysis of bone development in Xenopus tropicalis”, Finished in 2010
Mario SANCHEZ (Undergraduate thesis, TUTOR) “Molecular characterization of the Xenopus tropicalis osteocalcin promoter”, Finished in 2009


Premios y Distinciones

  •   Visiting Professor

    University of Paris 6

    Francia, 2013

    Visiting Professorship position from the University of Paris6, France, for one month during October 2013, at the UMR 7232 – Biologie Intégrative des Organismes Marins (BIOM), Observatoire Océanologique de Banyuls/Mer: -Collaboration with Dr. Hector Escriva (supervising of Daniel Aldea, a PhD student we are co-supervising, planning experiments, writing scientific articles together). -Collaboration with Dr. Laurent Sachs (scientific meetings, planning experiments, writing scientific articles togeher). -Seminar at the University of Paris 6 -Lectures for Master students (Genomics, Genetics)

  •   Visiting Professor

    University of Paris 6

    Chile, 2014

    Visiting Professorship position from the University of Paris6, France, for one month during October 2014, at the UMR 7232 – Biologie Intégrative des Organismes Marins (BIOM), Observatoire Océanologique de Banyuls/Mer: -Collaboration with Dr. Hector Escriva (supervising of Daniel Aldea, a PhD student we are co-supervising, planning experiments, writing scientific articles together). -Collaboration with Dr. Laurent Sachs (scientific meetings, planning experiments, writing scientific articles togeher). -Seminar at the University of Paris 6 -Lectures for Master students (Genomics, Genetics)


 

Article (25)

Genetic regulation of amphioxus somitogenesis informs the evolution of the vertebrate head mesoderm
Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates
Bone regeneration after traumatic skull injury in Xenopus tropicalis
Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families
The neuromuscular junction of Xenopus tadpoles: Revisiting a classical model of early synaptogenesis and regeneration
The Ric-8A/G?13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in xenopus
A Single Chance to Contact Multiple Targets: Distinct Osteocyte Morphotypes Shed Light on the Cellular Mechanism Ensuring the Robust Formation of Osteocytic Networks
Molecular footprinting of skeletal tissues in the catshark Scyliorhinus canicula and the clawed frog Xenopus tropicalis identifies conserved and derived features of vertebrate calcification
Cellular and molecular characterization of a novel primary osteoblast culture from the vertebrate model organism Xenopus tropicalis
A dynamic history of gene duplications and losses characterizes the evolution of the SPARC family in eumetazoans
Evolution of the vertebrate bone matrix: An expression analysis of the network forming collagen paralogues in amphibian osteoblasts
Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration
SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development
The vitamin C transporter SVCT2 is down-regulated during postnatal development of slow skeletal muscles
Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblasto]genesis
Two families of Xenopus tropicalis skeletal genes display well-conserved expression patterns with mammals in spite of their highly divergent regulatory regions
Vitamin D control of gene expression: Temporal and spatial parameters for organization of the regulatory machinery
An architectural perspective of vitamin D responsiveness
Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction
Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence
Two or four bristles: Functional evolution of an enhancer of scute in Drosophilidae
When Brachyury meets Smad1: the evolution of bilateral symmetry during gastrulation
A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor Poils-au-dos, a repressor of achaete-scute
achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila
Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria

EditorialMaterial (1)

Editorial: Evolution of Organismal Form: From Regulatory Interactions to Developmental Processes and Biological Patterns

Patent (1)

A bioassay based on the exogenous expressio of a highly sensitive AhR isoform for the detection of dioxins and similar compounds

Proyecto (6)

A Sox2/Sox9/FosL1 transcriptional code drives developmental and regenerative skull ossification
The evolution of the vertebrate head and the co-option of myogenic enhancers by the osteogenic regulatory network
Transcriptional enhancers invaded by highly repeated sequences: turning “junk DNA” into biologically relevant regulatory information
NEW ROLES OF RIC-8A: A PLEIOTROPIC REGULATOR OF CELL POLARITY AND MIGRATION DURING NEURAL CREST DEVELOPMENT
A fluorescence-based bioassay for the efficient detection of water ressources contaminated by toxic compunds
BIOCOP: A fast, sensitive and efficient detection of persistent organic pollutants

Review (4)

Aryl hydrocarbon receptor-based bioassays for dioxin detection: Thinking outside the box
Evolutionary Developmental Biology (Evo-Devo) Research in Latin America
Evolutionary origin of endochondral ossification: the transdifferentiation hypothesis
Control of osteogenesis by the canonical Wnt and BMP pathways in vivo
41
Sylvain Marcellini

Associate Professor

Department of Cell biology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

6
Marcela Torrejon

Associate Professor

Biochemistry and Molecular Biology

Biological Sciences Faculty

Concepcion, Chile

6
JUAN PABLO HENRIQUEZ

Associate Professor

Cell Biology

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPARTAMENTO DE BIOLOGÍA CELULAR

Concepción, Chile

5
David Muñoz

Investigador

Biologia Celular

Universidad de Concepción

Concepción, Chile

4
Martín Montecino

Director

Institute of Biomedical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

3
Fernando Cruzat

Profesor Asociado

Oceanografia

Universidad de Concepción

Concepción, Chile

2
Teresa Caprile

Associate profesor

DPTO. BIOLOGIA CELULAR,

UNIVERSIDAD DE CONCEPCIÓN

Concepcion, Chile

2
Jorge Ojeda

Académico investigador

Ciencias Básicas y Morfología

Universidad Católica de la Santisima Concepción

Concepción, Chile

2
Gloria Arriagada

Profesor Asociado-Investigador Principal

Instituto de Ciencias Biomédicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

1
Daniel Sandoval

Co-investigador

Ciencia Animal

UNIVERSIDAD DE CONCEPCIÓN

Chillán, Chile

1
Ariana Bertin

Investigadora

Departamento de Silvicultura

Universidad de Concepción

Concepción, Chile

1
Berta Henriquez

Profesor Asistente

Universidad San Sebastián

Santiago, Chile

1
Carola Bruna

Profesor Asociado

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS

Concepción, Chile

1
Nelson Osses

Associated Professor

Institute of Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO

Valparaíso, Chile

1
Soraya Gutierrez

Profesor Titular

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN

Concepcion, Chile

1
Nelson Osses

Profesor Titular

Instituto de Química

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile