Man

Bárbara Paz Pesce Reyes

Profesora Asistente

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Specialized in flow cytometry. I have developed in applying this technology to multiple fields of research. From immunology to fields as diverse as the study of signal transduction, pharmacology and cell biology. Autoinmune disease, Inmunology.

Educación

  •  Doctorado en Ciencias BIomédicas, UNIVERSIDAD DE CHILE. Chile, 2019
  •  Bioquimico, UNIVERSIDAD DE CHILE. Chile, 2007

Experiencia Académica

  •   Profesora Asistente Other

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2016 - At present

Experiencia Profesional

  •   Expert in Flow Cytometry Professional Full Time

    Universidad de Chile

    Santiago, Chile

    2015 - At present


 

Article (22)

TNF-alpha Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2

Pesce, Barbara; Ribeiro, Carolina H.; Larrondo, Milton; Ramos, Veronica; Soto, Lilian; Catalan, Diego; Aguillon, Juan Carlos

Article ISI
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2022)

Decreased invariant natural killer T-cell-mediated antitumor immune response in patients with gastric cancer

Ascui, Gabriel; Galvez-Jiron, Felipe; Kramm, Karina; Schafer, Carolina; Sina, Josefina; Pola, Victor; Cristi, Francisca; Hernandez, Carolina; Garrido-Tapia, Macarena; Pesce, Barbara; Bustamante, Marco; Fluxa, Paula; Molina, Maria C.; Ribeiro, Carolina H.

Article ISI
IMMUNOLOGY AND CELL BIOLOGY  (2020)

In vitro treatment of a murine mammary adenocarcinoma cell line with recombinant Trypanozoma cruzi calreticulin promotes inmunogenicity and phagocytosis.

Sosoniuk-Roche, Eduardo; Cruz P,; Maldonado I,; Duaso L,; Pesce B,; Michalak M,; Valck C,; Ferreira A.

Article
MOLECULAR IMMUNOLOGY  (2020)

Simvastatin improves cardiac function through Notch1 activation in BALB/c mice with chronic chagas cardiomyopathy

Guzman-Rivera D; Liempi A; Gonzalez-Herrera, F; Fuentes-Retamal, S.; Carrillo I; Abarca, P.; Castillo C.; Kemmerling U.; Pesce B,; Maya JD.

Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY  (2020)

Novel [1,2,3] triazolo[1,5-a]pyridine derivatives are trypanocidal by sterol biosynthesis pathway alteration

Lapier, Michel; Ballesteros-Garrido, Rafael; Guzman-Rivera, Daniela; Gonzalez-Herrera, Fabiola; Aguilera-Venegas, Benjamin; Moncada-Basualto, Mauricio; Ballesteros, Rafael; Abarca, Belen.; Pesce, Barbara; Kemmerling, Ulrike; Olea-Azar, Claudio; Maya, Juan D

Article ISI SCOPUS
FUTURE MEDICINAL CHEMISTRY  (2019)

Regulation of Tolerogenic Features on Dexamethasone-Modulated MPLA-Activated Dendritic Cells by MYC

Garcia-Gonzalez, Paulina A.; Maggi, Jaxaira; Schinnerling, Katina; Sepulveda-Gutierrez, Alejandro; Soto, Lilian; Neire, Oscar; Mehdi, Ahmed M.; Nel, Hendrik J.; Pesce, Barbara; Aravena, Octavio; Carmen Molina, Maria; Catalan, Diego; Thomas, Ranjeny; Verdugo, Ricardo A.; Carlos Aguillon, Juan

Article ISI SCOPUS
FRONTIERS IN IMMUNOLOGY  (2019)

Dexamethasone and Monophosphoryl lipid a induce a Distinctive Profile on Monocyte-Derived Dendritic cells through Transcriptional Modulation of genes associated With essential Processes of the immune response

Garcia-Gonzalez, PA; Schinnerling, K; Sepulveda-Gutierrez, A; Maggi, J; Mehdi, AM; Nel, HJ; Pesce, B; Larrondo, ML; Aravena, O; Molina, MC; Catalán, D; Thomas, R; Verdugo, RA; Aguillón, JC

Article ISI SCOPUS
Frontiers in immunology  (2017)

Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T cells

Maggi, J; Schinnerling, K; Pesce, B; Hilkens, CM; Catalán, D; Aguillón, JC

Article ISI SCOPUS
FRONTIERS IN IMMUNOLOGY  (2016)

Treatment with Dexamethasone and Monophosphoryl lipid a removes Disease-associated Transcriptional signatures in Monocyte-Derived Dendritic cells from rheumatoid arthritis Patients and confers Tolerogenic Features

Garcia-Gonzalez, PA; Schinnerling, K; Sepulveda-Gutierrez, A; Maggi, J; Hoyos, L; Morales, RA; Mehdi, AM; Nel, HJ; Soto, L; Pesce, B; Molina, MC; Cuchacovich, M; Larrondo, ML; Neira, O; Catalan, DF; Hilkens, CM; Thomas, R; Verdugo, RA; Aguillón, JC

Article ISI SCOPUS
FRONTIERS IN IMMUNOLOGY  (2016)

Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity

Cortes, LA; Castro L.; Pesce B,; Maya, JD; Ferreira J.; Castro-Castillo, V; Parra E.; Jara, JA; Lopez-Munoz, R

Article ISI SCOPUS
PLOS ONE  (2015)

Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin

Campos Estrada C; Liempi, A; Gonzalez-Herrera, F; Lapier, M.; Kemmerling U.; Pesce B,; Ferreira J.; Lopez-Munoz, R; Maya, JD

Article ISI SCOPUS
PLoS Neglected Tropical Diseases  (2015)

Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific T-Cell Responses and IgE Production

Escobar A.; Aguirre A.; Guzman, MA; González R.; Catalan, D; Acuna-Castillo, C; Larrondo M.; López MN; Pesce B,; Rolland J; O’hehir R.; Aguillón JC

Article ISI SCOPUS
PLOS ONE  (2014)

A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines

Garcia-Gonzalez, P; Morales R.; Hoyos L; Maggi, J; Campos J.; Pesce B,; Garate, D; Larrondo M.; González R.; Soto L.; Ramos, V; Tobar, P.; Molina, MC; Pino-Lagos, K; Catalan, D; Aguillón JC

Article ISI SCOPUS
Journal of Translational Medicine  (2013)

Blocking of p38 and transforming growth factor ss receptor pathways impairs the ability of tolerogenic dendritic cells to suppress murine arthritis

Garate, D; Rojas-Colonelli, N; Peña C; Salazar, L; Abello P; Pesce B,; Aravena, O; Garcia-Gonzalez, P; Ribeiro, CH; Molina, MC; Catalan, D; Aguillón JC

Article ISI SCOPUS
Arthritis and Rheumatism  (2013)

Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients

Pesce B,; Soto L.; Sabugo, F; Wurmann, P; Cuchacovich M.; López MN; Sotelo, PH; Molina, MC; Aguillón JC; Catalan, D

Article ISI SCOPUS
Clinical and Experimental Immunology  (2013)

A synthetic peptide homologous to IL-10 functional domain induces monocyte differentiation to TGF-beta plus tolerogenic dendritic cells

López MN; Pesce B,; Kurte, M; Pérez, C.; Segal G; Roa, J; Aguillón JC; Mendoza-Naranjo, A; Gesser B; Larsen C.; Villablanca A.; Choudhury A.; Kiessling R.; SALAZAR ONFRAY F

Article ISI SCOPUS
Immunobiology  (2011)

Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-gamma-producing NK cell and regulatory T cell subsets

Aravena, O; Pesce B,; Soto L.; Orrego, N.; Sabugo, F; Wurmann, P; Molina, MC; Alfaro, J; Cuchacovich M.; Aguillón JC; Catalan, D

Article ISI SCOPUS
Immunobiology  (2011)

Basal anti-cyclic citrullinated peptide (anti-CCP) antibody levels and a decrease in anti-CCP titres are associated with clinical response to adalimumab in rheumatoid arthritis

Cuchacovich M.; Catalan, D; Wainstein E.; Gatica H.; Soto L.; Aravena, O; Pesce B,; Sabugo, F; Aguillón JC

Article ISI SCOPUS
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY  (2008)

Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells

Salazar, L; Aravena, O; Abello P; Escobar A.; Contreras-Levicoy, J; Rojas-Colonelli, N; Catalan, D; Aguirre A.; Zúñiga R.; Pesce B,; González C; Cepeda R.; Cuchacovich M.; Molina, MC; SALAZAR ONFRAY F; Delgado M.; Toes, RE; Aguillón JC

Article ISI SCOPUS
ANNALS OF THE RHEUMATIC DISEASES  (2008)

Inflammation, synovial angiogenesis and chondroid apoptosis in the evolution of type II collagen-induced arthritis

González C; Abello P; Cepeda R.; Salazar, L; Aravena, O; Pesce B,; Catalan, D; Aguillón JC

Article ISI SCOPUS
European Cytokine Network  (2007)

Short-term lipopolysaccharide stimulation indeces differentiation of murine bone marrow-derived dentritic cells into tolerogenic phenotype

Salazar, L; Aravena, O; Contreras-Levicoy, J; Pesce B,; Catalan, D; Zúñiga R.; Iruretagoyena M.; Kalergis, AM; Aguillón JC

Article ISI SCOPUS
European Cytokine Network  (2007)

Multiple imputation procedures allow the rescue of missing data: An application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy

Schiattino, I; Villegas, R; Cruzat, A; Cuenca J.; Salazar, L; Aravena, O; Pesce B,; Catalan, D; Llanos, C.; Cuchacovich M.; Aguillón JC

Article ISI SCIELO SCOPUS
BIOLOGICAL RESEARCH  (2005)

Abstract (5)

In Vitro Generated Human Dendritic Cells Exposed to a Potent Maturation Melanoma Cell Lines Lysate Show a Tolerogenic-like Phenotype and Functionality When Exposed to Dexamethasone Prior to the Maturation Stimuli

Falcon-Beas, C; Tempio F.; Pesce B,; Aguillon, J.; Pereda, C; Saffie C; SALAZAR ONFRAY F; López MN

Abstract ISI
EUROPEAN JOURNAL OF CANCER  (2012)

ANTI-TNF THERAPY INDUCES CHANGES ON T CELLS AND NK CELLS SUB-POPULATIONS IN RHEUMATOID ARTHRITIS PATIENTS

Catalán DF; Pesce B,; Aravena, O; Orrego, N.; Soto L.; Sabugo, F; Wurmann, P; Cuchacovich M.; Aguillón JC

Abstract ISI
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY  (2011)

Adalimumab, a Tumor Necrosis Factor Blockade Therapy, Decreases Th1 and Th17 Populations in Rheumatoid Arthritis Patients

Pesce B,; Catalan, D; Orrego, N.; Aravena, O; Soto L.; Wurman, P; Sabugo, F; Cuchacovich M.; Aguillon, J.

Abstract ISI
CLINICAL IMMUNOLOGY  (2010)

Basal anti-cyclic citrullinated peptide (anti-ccp) antibodies levels and a decrease in anti-CCP titres are associated with clinical response to adalimumab therapy in rheumatoid arthritis patients

Cuchacovich M.; Catalan, D; Wainstein E.; Gatica H.; Soto L.; Aravena, O; Pesce B,; Sabugo, F; Aguillon, J.

Abstract ISI
ANNALS OF THE RHEUMATIC DISEASES  (2007)

Established murine collagen-induced arthritis and IL-17 production are specifically inhibited by a single inoculation of lipopolysaccharide-stimulated dendritic cells

Aguillón JC; Salazar, L; Araveno, O; González C; Abello P; Contreras-Levicoy, J; Pesce B,; SALAZAR ONFRAY F; Cuchacovich M.

Abstract ISI
CLINICAL IMMUNOLOGY  (2007)

Review (1)

Emergent therapies for rheumatoid arthritis

Aguillón JC; Cruzat, A; Contreras-Levicoy, J; Dotte, A; Pesce B,; Aravena, O; Salazar, L; Catalan, D; Abello P; Aguirre A.; Llanos, C.; Cuchacovich M.

Review ISI
REVISTA MEDICA DE CHILE  (2005)

28
Bárbara Pesce

Profesora Asistente

ICBM

Universidad de Chile

Santiago, Chile

18
Diego Catalán

Associate Professor

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

15
JUAN AGUILLON

PROFESSOR

IMMUNOLOGY PROGRAM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

13
OCTAVIO ARAVENA

Gestión I+D

I+D+i

Comisión Chilena de Energía Nuclear

Santiago, Chile

10
MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

8
Lilian Soto

Rheumatologist

Medicine

CLINICAL HOSPITAL OF UNIVERSIDAD DE CHILE

Santiago, Chile

7
Lorena Salazar

Profesora Asistente

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Lampa, Chile

6
Lorena Salazar

Academico

Instituto Cs Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

6
Maria Sabugo

Medico Reumatologo

Medicina

UNIVERSIDAD DE CHILE HOSPITAL CLÍNICO

Santiago, Chile

5
Paula Abello

Docente Adjunto

Ciencias Biológicas

Universidad San Sebastián

Santiago, Chile

4
Katina Schinnerling

Profesor Asistente

Departamento de Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

3
Paulina García

Investigador Postdoctoral

Programa de Inmunologia

Universidad de Chile

Santiago, Chile

3
Pamela Wurmann

reumatologa

medicina

universidad de chile

santiago, Chile

3
Ricardo Verdugo

Asistant Professor

Facultad de Medicina

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Alejandro Escobar

assistant professor

Institute for Research in Dental Sciences

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Rodrigo Lopez

Profesor Asociado

Facultad de Ciencias Veterinarias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Fabiola González

Investigadora Postdoctoral

Universidad de Chile

Santiago, Chile

2
Roberto Zúñiga

Investigador Asociado a Proyectos

Programa Disciplinario de Inmunologia

Universidad de Chile/ Facultad de Medicina

Santiago, Chile

2
Michel Lapier

Académico

Química y Farmacia

Universidad de Valparaíso

Valparaíso, Chile

2
Carolina Llanos

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Ulrike Kemmerling

Full Professor

ICBM

Facultad de Medicina, Universidad de Chile

Santiago, Chile

1
José Jara

Assistant Professor

Research Institute of Dental Sciences

Universidad de Chile

Santiago, Chile

1
Rodrigo Villegas

Jefe Programa de Bioestadística

Bioestadística

Universidad de Chile - Facultad de Medicina

Santiago, Chile

1
Karina Pino

Group Leader/Associate Professor

Centro de Investigación Biomédica

Universidad de los Andes

Santiago, Chile

1
Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Carolina Campos

Associate Professor

School of Chemistry and Pharmacy

Universidad de Valparaiso

Valparaíso, Chile

1
Mónica Kurte

Investigador

Laboratorio de Inmunologìa

Universidad de los Andes

Santiago, Chile

1
Eduardo Parra

ACADÉMICO - ESCUELA DE MEDICINA

MEDICINA

UNIVERSIDAD DE TARAPACA

Arica, Chile

1
Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

1
Juan Maya

Full Professor

Biomedical Sciences Institute

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Fabian Tempio

Asistente de Investigación

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

1
Mirentxu Iruretagoyena

Jefe Seccion Inmunologia

Laboratorio Clinico

Clinica Alemana de Santiago

Santiago, Chile

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
Ana Liempi

Investigador

Instituto de Ciencia Biomedica

Universidad de Chile, Facultad de Medicina

Santiago, Chile

1
Veronica Ramos

Bioquímico

Inmunologia, VIH y Alergias

Hospital Clínico Universidad de Chile

Santiago, Chile

1
Rodrigo Morales

Postdoctoral researcher

Dept. of Medicine Solna (MedS)

Karolinska Institutet

Stockholm, Suecia

1
Mauricio Moncada

1
Javier Campos

Gestor de Propiedad Intelectual

Universidad Tecnológica Metropolitana

Santiago, Chile

1
Felipe Galvez

Estudiante Doctorado

Universidad de La Frontera

Temuco, Chile

1
Jimena Cuenca

Investigador/profesor

Facultad de Medicina

Universidad de Los Andes

Santiago, Chile