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Juan Antonio Valdés Muñoz

Head lab

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Fish molecular endocrinology; skeletal muscle growth physiology; Biotechnology; Functional genomics; OMICs technologies

Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000
Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000
Biomedical science, UNIVERSIDAD DE CHILE. Chile, 2007
computer analyst and programmer, Escuela de asistentes Tecnicos. Chile, 1996

Assistant Professor Part Time

UNIVERSIDAD DE CHILE

Medicina Norte

Santiago, Chile

2006 - 2007
Associated Professor Full Time

UNIVERSIDAD ANDRES BELLO

Ciencias Biologicas

Santiago, Chile

2007 - At present
Profesor titular Full Time

UNIVERSIDAD ANDRES BELLO

Ciencias de la Vida

Santiago, Chile

2021 - At present

Academic Secretary, Engineering in Biotechnology School Full Time

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2007 - 2013
Director, Carrera Ingeniería en Biotecnología Full Time

Universidad Andres Bello

Santiago, Chile

2017 - At present

Nombre Alumno: Zuloaga, Rodrigo
Título tesis: "Regulación de la expresión génica de miostatina inducida por IGF-1 mediada por el factor de transcripción CREB durante la diferenciación de los mioblastos",
Institución: UNIVERSIDAD ANDRES BELLO, Magíster en Biotecnologia, 2013

Nombre Alumno: Retamales, Andrea
Título tesis: "Regulación de la vía de señalización Miostatina/Smad3 mediada por IGF-1/PI3K/Akt durante la diferenciación de mioblastos",
Institución: UNIVERSIDAD ANDRES BELLO, Magíster en Biotecnología, 2013

Nombre Alumno: Pino, Katherine;Estrada, Cristal; Fernandez, Macarena;Ortiz, Yarin
Título tesis: "Estudio del efecto de IGF-1 sobre la expresión de miostatina, a través de las vías de señalización Akt y ERK, en músculo esquelético",
Institución: UNIVERSIDAD ANDRES BELLO, Tecnología Medica, 2011

Nombre Alumno: Quezada, Andres
Título: "La vía de señalización IGF-I/Calcineurina/MEF2 participa en la regulación de la expresión génica de miostatina durante la diferenciación de los mioblastos",
Institución: UNIVERSIDAD ANDRES BELLO, Magíster en biotecnología, 2014

Nombre Alumno: Aedo, Jorge
Título: "Evaluación del efecto de estrés por manejo en la expresión de genes asociados al crecimiento muscular en Congrio colorado (Genypterus chilensis)",
Institución: UNIVERSIDAD ANDRES BELLO, Magíster en Bioquímica, 2014

Nombre Alumno: Fuentes, Eduardo
Título: "Molecular and Endocrine Mechanisms that Regulate Skeletal Muscle Growth in the Fine Flounder (Paralichthys adspersus) ",
Institución: UNIVERSIDAD ANDRES BELLO, Doctorado en Biotecnologia, 2012

Nombre Alumno: Lara, Hernan
Título: "Evaluación de los componentes de la vía ILPs (insulin like-peptides) durante restricción nutricional en Chorito Chileno (Mytilus chilensis) ",
Institución: UNIVERSIDAD ANDRES BELLO, Magister en Biotecnologia, 2017

Nombre Alumno: Aballai, Victor
Título: "Evaluación del efecto del estrés por manejo en la expresión de genes asociados a la regulación del sistema inmune de congrio colorado (Genypterus chilensis) mediante RNA-seq ",
Institución: UNIVERSIDAD ANDRES BELLO, Magister en Biotecnologia, 2017

Nombre Alumno: Antiqueo, Paulette
Título: "Caracterización del transcriptoma del erizo chileno (Loxechinus albus) utilizando secuenciación masiva. ",
Institución: UNIVERSIDAD ANDRES BELLO, Magister en Biotecnologia, 2017

Nombre Alumno: Donoso, Juan Pablo
Título: "Caracterización de microRNAs asociados a la respuesta a estrés por confinamiento en músculo esquelético del lenguado chileno Paralichthys adspersus"
Institución: UNIVERSIDAD ANDRES BELLO, Magister en Bioquímica, 2017

Nombre Alumno: Naour, Sebastian
Título: "Efecto de estrés por manejo en la expresión de genes involucrados en fibrosis del tejido hepático de congrio colorado (Genypterus chilensis)"
Institución: UNIVERSIDAD ANDRES BELLO, Ingenieria en Biotecnología, 2016

Nombre Alumno: Jorge Aedo
Título: Molecular mechanisms of the membrane-initiated cortisol actions on the teleost stress response
Institución: UNIVERSIDAD ANDRES BELLO, Doctorado en Biotecnología, 2020

Nombre Alumno: Denisse Alegria
Título: Análisis de la expresión de decorina en músculo esquelético de trucha arcoíris (Oncorhynchus mykiss) bajo tratamiento con cortisol
Institución: UNIVERSIDAD ANDRES BELLO, Ingenieria en Biotecnología, 2021

Nombre Alumno: Daniela Aravena
Título: Efectos de cortisol sobre la modulación temprana de atrogina-1 y murf1 en músculo esquelético de trucha arcoíris (Onchorynchus mykiss)
Institución: UNIVERSIDAD ANDRES BELLO, Ingenieria en Biotecnología, 2019

Revista Salmon Expert Nº 39 Año 5 Mayo 2016 “Mecanismos no-genómicos mediados por cortisol en la respuesta adaptativa frente al estrés en trucha arcoíris (Oncorhynchus mykiss).

Ph.D. Fellowship

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2003

Ph.D. Fellowship
Post-Doctoral research Fellowship

Centro de Estudios Moleculares de la Celula

Chile, 2007

FONDAP Post-Doc fellowship
Alberto Zanlungo Fellowship

UNIVERSIDAD DE SANTIAGO DE CHILE

Chile, 1997

Academic excelence fellowship


RNA-Seq-Based Analysis of Cortisol-Induced Differential Gene Expression Associated with Piscirickettsia salmonis Infection in Rainbow Trout (Oncorhynchus mykiss) Myotubes Zuloaga, Rodrigo; Dettleff, Phillip; Bastias-Molina, Macarena; Meneses, Claudio; Altamirano, Claudia; Antonio Valdes, Juan; Molina, Alfredo Article ISI Animals (2021)
Transcriptomic analysis reveals a Piscirickettsia salmonis-induced early inflammatory response in rainbow trout skeletal muscle Carrizo, Victoria; Valenzuela, Cristian A.; Aros, Camila; Dettleff, Phillip; Valenzuela-Munoz, Valentina; Gallardo-Escarate, Cristian; Altamirano, Claudia; Molina, Alfredo; Valdes, Juan Antonio Article ISI COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS PROTEOMICS (2021)
Identification and Evaluation of Long Noncoding RNAs in Response to Handling Stress in Red Cusk-Eel (Genypterus chilensis) via RNA-seq Dettleff P.; Hormazabal E.; Aedo, J.; Fuentes M.; Meneses C.; Molina A.; Valdes J.A. Article ISI SCOPUS MARINE BIOTECHNOLOGY (2020)
Early transcriptomic responses associated with the membrane-initiated action of cortisol in the skeletal muscle of rainbow trout (Oncorhynchus mykiss) Aedo, Jorge E; Zuloaga, Rodrigo; Bastias-Molina, Macarena; Meneses, Claudio; Boltaña, Sebastian; Molina, Alfredo; Valdes, Juan Antonio Article ISI SCOPUS PHYSIOLOGICAL GENOMICS (2019)
Membrane-initiated cortisol action modulates early pyruvate dehydrogenase kinase 2 (pdk2) expression in fish skeletal muscle Aedo J.E.; Zuloaga R.; BoltaÃ±a S.; Molina A.; ValdÃ©s J.A. Article ISI SCOPUS COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2019)
Stocking density induces differential expression of immune-related genes in skeletal muscle and head kidney of fine flounder (Paralichthys adspersus) Valenzuela C.A.; Escobar-Aguirre S.; Zuloaga R.; Vera-Tobar T.; Mercado L.; BjÃ¶rnsson B.T.; ValdÃ©s J.A.; Molina A. Article ISI SCOPUS VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2019)
Chronic stress inhibits growth and induces proteolytic mechanisms through two different nonoverlapping pathways in the skeletal muscle of a teleost fish Valenzuela, Cristian A.; Zuloaga, Rodrigo; Mercado, Luis; Eir Einarsdottir, Ingibjorg; Thrandur Bjornsson, Bjorn; Antonio Valdes, Juan; Molina, Alfredo Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)
Oceanographic upwelling conditions influence signaling pathways involved in muscle growth of intertidal fish Zuloaga, Rodrigo; Almarza, Oscar; Valdes, Juan A.; Molina, Alfredo; Pulgar, Jose Article ISI SCOPUS COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2018)
RNA-seq analysis of compensatory growth in the skeletal muscle of fine flounder (Paralichthys adspersus) Mendez, Katterinne N.; Zuloaga, Rodrigo; Valenzuela, Cristian A.; Bastias-Molina, Macarena; Meneses, Claudio.; Vizoso, Paula; Antonio Valdes, Juan; Molina, Alfredo Article ISI SCOPUS AQUACULTURE (2018)
Thermal Modulation of Monoamine Levels Influence Fish Stress and Welfare Sanhueza, Nataly; Donoso, Andrea; Aguilar, Andrea; Farlora, Rodolfo; Carnicero, Beatriz; Manuel Miguez, Jesus; Tort, Lluis; Antonio Valdes, Juan; Boltana, Sebastian Article ISI FRONTIERS IN ENDOCRINOLOGY (2018)
Cortisol Induces Reactive Oxygen Species Through a Membrane Glucocorticoid Receptor in Rainbow Trout Myotubes Espinoza, Marlen B.; Aedo, Jorge E.; Zuloaga, Rodrigo; Valenzuela, Cristian; Molina, Alfredo; Valdés, Juan A. Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
Cytotoxic activity of Flavobacterium psychrophilum in skeletal muscle cells of rainbow trout (Oncorhynchus mykiss) Iturriaga M.; Espinoza M.B.; Poblete-Morales M.; Feijoo C.G.; Reyes A.E.; Molina A.; Avendaño-Herrera R.; Valdés J.A. Article ISI SCOPUS VETERINARY MICROBIOLOGY (2017)
Fish skeletal muscle tissue is an important focus of immune reactions during pathogen infection Valenzuela, Cristián A.; Zuloaga, Rodrigo; Poblete-Morales, Matías; Vera-Tobar, Tamara; Mercado, Luis; Avendaño-Herrera, Ruben; Valdés, Juan Antonio; Molina, Alfredo Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2017)
Influences of thermal environment on fish growth Boltaña, Sebastián; Sanhueza, Nataly; Aguilar, Andrea; Gallardo-Escárate, Cristian; Arriagada, Gabriel; Valdés, Juan Antonio; Soto, Doris; Quiñones, Renato A. Article ISI SCOPUS ECOLOGY AND EVOLUTION (2017)
RNA-seq analysis of the head-kidney transcriptome response to handling-stress in the red tusk-eel (Genypterus chilensis) Aballai, Víctor; Aedo, Jorge E.; Maldonado, Jonathan; Bastias-Molina, Macarena; Silva, Herman; Meneses, Claudio; Boltaña, Sebastian; Reyes, Ariel; Molina, Alfredo; Valdés, Juan Antonio Article ISI SCOPUS COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS PROTEOMICS (2017)
Transcriptomic analysis of the hepatic response to stress in the red cusk-eel (Genypterus chilensis): Insights into lipid metabolism, oxidative stress and liver steatosis Naour, Sebastian; Espinoza, Brisa M.; Aedo, Jorge E.; Zuloaga, Rodrigo; Maldonado, Jonathan; Bastias-Molina, Macarena; Silva, Herman; Meneses, Claudio; Gallardo-Escárate, Cristian; Molina, Alfredo; Valdés, Juan Antonio; Chen, Tzong-Yueh Article ISI SCOPUS PLOS ONE (2017)
Upwelling-derived oceanographic conditions impact growth performance and growth-related gene expression in intertidal fish Fuentes E.N.; Zuloaga R.; Almarza O.; Mendez K.; Valdés J.A.; Molina A.; Pulgar J. Article ISI SCOPUS COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2017)
RNA interference in Haliotis rufescens myostatin evidences upregulation of insulin signaling pathway Carrera-Naipil, Crisleri; Valenzuela-Muñoz, Valentina; Valdés, Juan Antonio; Molina, Alfredo; Gallardo-Escárate, Cristian Article SCOPUS Agri Gene (2016)
Bacterial lipopolysaccharide induces rainbow trout myotube atrophy via Akt/FoxO1/Atrogin-1 signaling pathway Aedo, JE; Reyes, AE; Avendano-Herrera, R; Molina A.; Valdes, JA Article ISI SCOPUS Acta Biochimica et Biophysica Sinica (2015)
Insulin-like growth factor-1 suppresses the Myostatin signaling pathway during myogenic differentiation Retamales A.; Zuloaga R.; Valenzuela CA; Gallardo-Escarate, C; Molina A.; Valdes, JA Article ISI SCOPUS Biochemical and Biophysical Research Communications (2015)
mRNA-seq reveals skeletal muscle atrophy in response to handling stress in a marine teleost, the red cusk-eel (Genypterus chilensis) Aedo, JE; Maldonado J.; Aballai V.; Estrada, JM; Bastias-Molina, M; Meneses, C.; Gallardo-Escarate, C; Silva H.; Molina A.; Valdes, JA Article ISI BMC GENOMICS (2015)
Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio) Solis, CJ; Poblete-Morales, M; Cabral, S; Valdes, JA; Reyes, AE; Avendano-Herrera, R; Feijoo, CG Article ISI SCOPUS Journal of Immunology Research (2015)
The TORC1/P70S6K and TORC1/4EBP1 signaling pathways have a stronger contribution on skeletal muscle growth than MAPK/ERK in an early vertebrate: Differential involvement of the IGF system and atrogenes Fuentes E.N.; Einarsdottir I.E.; Paredes, R.; Hidalgo C.; Valdes J.A.; Bjornsson B.T.; Molina A. Article ISI SCOPUS GENERAL AND COMPARATIVE ENDOCRINOLOGY (2015)
Transcriptional dynamics of immune, growth and stress related genes in skeletal muscle of the fine flounder (Paralichthys adpersus) during different nutritional statuses Valenzuela CA; Escobar, D.; Perez, L.; Zuloaga R.; Estrada, JM; Mercado L.; Valdes, JA; Molina A. Article ISI SCOPUS Developmental & Comparative Immunology (2015)
Sequencing and de novo assembly of the red cusk-eel (Genypterus chilensis) transcriptome Aedo J.E.; Maldonado J.; Estrada J.M.; Fuentes E.N.; Silva H.; Gallardo-Escarate, C; Molina A.; Valdes J.A. Article ISI SCOPUS MARINE GENOMICS (2014)
Skeletal muscle plasticity induced by seasonal acclimatization in carp involves differential expression of rRNA and molecules that epigenetically regulate its synthesis Fuentes EN, Zuloaga R, Nardocci G, Fernandez de la Reguera C, Simonet N, Fumeron R, Valdes JA, Molina A, Alvarez M. Article ISI SCOPUS COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2014)
Skeletal muscle plasticity induced by seasonal acclimatization involves IGF1 signaling: Implications in ribosomal biogenesis and protein synthesis Fuentes EN, Zuloaga R, Valdes JA, Molina A, Alvarez M. Article ISI COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2014)
The vertebrate muscle-specific RING finger protein family includes MuRF4-A novel, conserved E3-ubiquitin ligase Macqueen, DJ; Fuentes, EN; Valdes, JA; Molina A.; Martin, SAM Article ISI SCOPUS FEBS LETTERS (2014)
IGF-1 induces IP3-dependent calcium signal involved in the regulation of myostatin gene expression mediated by NFAT during myoblast differentiation Valdes, JA; Flores, S; Fuentes, EN; Osorio-Fuentealba, C; Jaimovich E.; Molina A. Article ISI SCOPUS Journal of Cellular Physiology (2013)
Isolation and selection of suitable reference genes for real-time PCR analyses in the skeletal muscle of the fine flounder in response to nutritional status: assessment and normalization of gene expression of growth-related genes Fuentes, EN; Safian, D; Valdes, JA; Molina A. Article ISI SCOPUS Fish Physiology and Biochemistry (2013)
Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder Fuentes, EN; Safian, D; Einarsdottir, IE; Valdes, JA; Elorza, AA; Molina A.; Bjornsson, BT Article ISI SCOPUS General and Comparative Endocrinology (2013)
Regulation of skeletal muscle growth in fish by the growth hormone - Insulin-like growth factor system Fuentes, EN; Valdes, JA; Molina A.; Bjornsson, BT Article ISI SCOPUS General and Comparative Endocrinology (2013)
The cAMP Response Element Binding protein (CREB) is activated by Insulin-like Growth Factor-1 (IGF-1) and regulates myostatin gene expression in skeletal myoblast Zuloaga R.; Fuentes, EN; Molina A.; Valdes, JA Article ISI SCOPUS Biochemical and Biophysical Research Communications (2013)
Transient inactivation of myostatin induces muscle hypertrophy and overcompensatory growth in zebrafish via inactivation of the SMAD signaling pathway Fuentes, EN; Pino, K; Navarro, C.; Delgado, I; Valdes, JA; Molina A. Article ISI SCOPUS Journal of Biotechnology (2013)
Catabolic Signaling Pathways, Atrogenes, and Ubiquitinated Proteins Are Regulated by the Nutritional Status in the Muscle of the Fine Flounder Fuentes E.N.; Ruiz, P; Valdes J.A.; Molina A. Article ISI SCOPUS PLOS ONE (2012)
Dynamic transcriptional regulation of autocrine/paracrine igfbp1, 2, 3, 4, 5, and 6 in the skeletal muscle of the fine flounder during different nutritional statuses Safian, D; Fuentes E.N.; Valdes J.A.; Molina A. Article ISI SCOPUS Journal of Endocrinology (2012)
Inherent Growth Hormone Resistance in the Skeletal Muscle of the Fine Flounder Is Modulated by Nutritional Status and Is Characterized by High Contents of Truncated GHR, Impairment in the JAK2/STAT5 Signaling Pathway, and Low IGF-I Expression Fuentes E.N.; Einarsdottir I.E.; Valdes J.A.; Alvarez M.; Molina A.; Bjornsson B.T. Article ISI SCOPUS Endocrinology (2012)
Inherent growth hormone resistance in the skeletal muscle of the fine flounder is modulated by nutritional status and is characterized by high contents of truncated GHR, impairment in the JAK2/STAT5 signaling pathway, and low IGF-I expression. Fuentes E.N.; Einarsdottir I.E.; Valdes J.A.; Alvarez M.; Molina A.; BjÃ¶rnsson B.T. Article SCOPUS ENDOCRINOLOGY (2012)
Plasma leptin and growth hormone levels in the fine flounder (Paralichthys adspersus) increase gradually during fasting and decline rapidly after refeeding Fuentes E.N.; Kling P.; Einarsdottir I.E.; Alvarez M.; Valdes J.A.; Molina A.; Bjornsson B.T. Article ISI SCOPUS General and Comparative Endocrinology (2012)
High-Frequency Field Stimulation of Primary Neurons Enhances Ryanodine Receptor-Mediated Ca2+ Release and Generates Hydrogen Peroxide, Which Jointly Stimulate NF-kappa B Activity Riquelme, D.; Alvarez A.; Leal, N; Adasme, T.; Espinoza, I; Valdes, JA; Troncoso, N.; Hartel, S; Hidalgo J.; Hidalgo C.; Carrasco MA Article ISI SCOPUS Antioxidants and Redox Signaling (2011)
IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder Fuentes, Eduardo N.; Bjornsson, Bjorn Thrandur; Antonio Valdes, Juan; Einarsdottir, Ingibjorg Eir; Lorca, Belen; Alvarez, Marco; Molina, Alfredo Article ISI AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder Fuentes, EN; Bjornsson, BT; Valdes, JA; Einarsdottir, IE; Lorca B., Álvarez; M., Molina Article AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
Molecular cloning of IGF-1 and IGF-1 receptor and their expression pattern in the Chilean flounder (Paralichthys adspersus) Escobar, S; Fuentes, EN; Poblete E.; Valdes, JA; Safian, D; Reyes, AE; Alvarez M.; Molina A. Article ISI SCOPUS Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (2011)
Hypoxia stimulates via separate pathways ERK phosphorylation and NF-kappa B activation in skeletal muscle cells in primary culture Osorio-Fuentealba, C; Valdes, JA; Riquelme, D.; Hidalgo J.; Hidalgo C.; Carrasco MA Article ISI SCOPUS JOURNAL OF APPLIED PHYSIOLOGY (2009)
NFAT activation by membrane potential follows a calcium pathway distinct from other activity-related transcription factors in skeletal muscle cells Valdes, JA; Gaggero, E.; Hidalgo J.; Leal, N; Jaimovich E.; Carrasco MA Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
NF-kappa B activation by depolarization of skeletal muscle cells depends on ryanodine and IP3 receptor-mediated calcium signals Valdes, JA; Hidalgo J.; Galaz, JL; Puentes, N; Silva M.; Jaimovich E.; Carrasco MA Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Genome assembly and particle maturation of the birnavirus infectious pancreatic necrosis virus Villanueva, RA; Galaz, JL; Valdes, JA; Jashes, MM; Sandino, AM Article ISI SCOPUS JOURNAL OF VIROLOGY (2004)


IGF-1 induces myostatin expression through differential activation of the signaling pathways PI3K/Akt, Calcineurin/NFAT, ERK/CREB, CamK-MEF, Smad2/3 during myoblast proliferation and differentiation Flores, S; Zuloaga R.; Retamales A.; Andrade, C; Pino, K; Molina A.; Valdes, JA Abstract ISI NEUROMUSCULAR DISORDERS (2011)
Crosstalk between myostatin and IGF-1 signalling pathways during myoblast proliferation and differentiation Valdes, JA; Flores, S; Molina A. Abstract ISI NEUROMUSCULAR DISORDERS (2010)


Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder (vol 186, pg 172, 2013) Fuentes, EN; Safian, D; Einarsdottir, IE; Valdes, JA; Elorza, AA; Molina A.; Bjornsson, BT Errata ISI SCOPUS General and Comparative Endocrinology (2015)


Challenging the stress response paradigm in fish: role of cortisol membrane-initiated signaling in metabolic adaptations of skeletal muscle Valdés, Juan Antonio; Molina, Alfredo; Boltaña, Sebastian Proyecto (2017)
Pathogen-induced immune-like response of fish skeletal muscle: stress-induced immunosuppression and growth impairment. Molina, Alfredo; Valdés, Juan Antonio Proyecto (2017)
Effect of chronic stress response triggered by fish farming conditions on endocrine and molecular signaling pathways involved in muscle growth in the fine flounder Molina, Alfredo; Valdés, Juan Antonio Proyecto (2013)
Análisis de las vías de señalización gavilladas por el eje GH/IGF-I/miostatina en músculo de lenguado chileno: Efecto de la restricción nutricional y el crecimiento compensatorio. Molina, Alfredo; Valdés, Juan Antonio Proyecto (2009)
Cross talk between myostatin and IGF-1 signaling pathways during myogenesis Valdés, Juan Antonio Proyecto (0)
Desarrollo de la Tecnología para el Cultivo Intensivo del Congrio Colorado: Fase II engorda. Ramirez, Diego; Estrada, Juan Manuel; Valdés, Juan Antonio; Molina, Alfredo Proyecto (0)
Interdisciplinary Center for Aquaculture Research (INCAR). Quiñones, Renato; Gallardo, Cristian; Avendaño, Ruben; Figueroa, Jaime; Valdés, Juan Antonio; Molina, Alfredo Proyecto (0)

Juan Valdés

Head lab

Ciencias Biologicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Alfredo Molina

UNIVERSIDAD ANDRES BELLO

SANTIAGO, Chile

Jorge Aedo

Profesor Auxiliar

Biología y Química

Universidad Católica del Maule

Talca, Chile

Cristian Gallardo

Profesor Asociado

Departamento de Oceanografía

Universidad de Concepción

Concepcion, Chile

Eduardo Fuentes

Founder and CEO

BioPub

santiago, Chile

Sebastian Boltana

Profesor Asociado

Occeanografia

Universidad de Concepcion

Concpecion, Chile

Marco Alvarez

Full Professor

Department of Biological Science

Universidad Andres Bello

Viña del Mar, Chile

Claudio Meneses

Profesor Asociado

Facultad de Agronomía e Ingeniería Forestal/ Facultad de Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago, Chile

Herman Silva

Professor

Departamento de Produccion Agricola

Universidad de Chile

Santiago, Chile

Ruben Avendaño

Full Professor

UNIVERSIDAD ANDRÉS BELLO

Viña del Mar, Chile

LUIS MERCADO

Profesor Titular

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

JONATHAN MALDONADO

Postdoc CONICYT

Dpto. Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Phillip Dettleff

Profesor asistente

Escuela de Medicina Veterinaria, Pontificia Universidad Católica de Chile

Santiago, Chile

Matías Poblete

Head of Microbiology Development

R&D

Veterquimica S.a

Santiago, Chile

Juan Manuel Estrada

Director

Facultad de Ecología y Recursos Naturales

Universidad Andrés Bello

Quintay , Chile

Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Denise Riquelme

Adjunct Professor

Biology

Universidad de Santiago

Santiago, Chile

César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

José Galaz

Estudiante de Posgrado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

José Pulgar

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

Alvaro Elorza

FULL PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

sebastian escobar

PROFESOR ASISTENTE

CIENCIAS ANIMALES

Pontificia Universidad Católica de Chile

santiago, Chile

Cristián Valenzuela

Rodolfo Farlora

Full time professor

Instituto de Biología

Universidad de Valparaíso

Valparaiso, Chile

Mónica Silva

Lab Manager

Fisiología y Biofísica

Universidad de Chile

Santiago, Chile

Gabriel Arriagada

Profesor Asociado

Instituto de Ciencias Agroalimentarias, Animales y Ambientales (ICA3)

Universidad de O'Higgins

San Fernando, Chile

RODOLFO PAREDES

Medical Education and Clinical Simulation Director

Academic Vice Rectory

UNIVERDAD ANDRÉS BELLO

Santiago, Chile

Pamela Ruiz

Investigador

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

DORIS Soto

Investigador Principal

Oceanografia

Universidad de Concepcion

Puerto Montt, Chile

Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

PAULA VIZOSO

Researcher

Universidad Mayor

SANTIAGO, Chile

Camila Solís

Docente Hora / Investigador Lab. Inmunología en Peces

Biología

Universidad Andrés Bello

Santiago, Chile

Orozimba Delgado

Profesor Asociado

Facultad de Medicina Clinica Alemana Universidad del Desarrollo

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Italo Espinoza

Lab Manager

Centro de Biología Integrativa

Universidad Mayor de Chile

Santiago, Chile

Andrea Donoso

Investigadora y encargada de Gestión Tecnológica

Centro de Biotecnología

Universidad de Concepción

concepcion, Chile

Tatiana Adasme

Coordinadora de Estudios

Oficina de Apoyo a la Investigación Clínica

Universidad Chile

Santiago, Chile

Ana Sandino

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

Valentina Valenzuela

Investigador adjunto

Universidad de Concepcion

Concepción, Chile

Juan Antonio Valdés Muñoz

Líneas de Investigación

Educación

Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000

Biochemistry, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2000

Biomedical science, UNIVERSIDAD DE CHILE. Chile, 2007

computer analyst and programmer, Escuela de asistentes Tecnicos. Chile, 1996

Experiencia Académica

Assistant Professor Part Time

Associated Professor Full Time

Profesor titular Full Time

Experiencia Profesional

Academic Secretary, Engineering in Biotechnology School Full Time

Director, Carrera Ingeniería en Biotecnología Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Ph.D. Fellowship

Post-Doctoral research Fellowship

Alberto Zanlungo Fellowship

Article (47)

Abstract (2)

Errata (1)

Proyecto (7)